| Compound ID |
Compound Name |
Compound Formula |
|
CP0035720
|
(-)-reserpine
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|
C33H40N2O9
|
5
|
| 1 |
IC50 = 13.2 nM
|
|
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| 2 |
Kd = 8 nM
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| 3 |
Ki = 5.26 nM
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| 4 |
Ki = 410 nM
|
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| 5 |
Ki = 630 nM
|
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CP0542828
|
ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-phenylpiperidine-3-carboxylate
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|
C24H27N3O4
|
4
|
| 1 |
IC50 = 19.7 nM
|
|
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| 2 |
Ki = 70 nM
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|
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| 3 |
Ki = 287 nM
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| 4 |
Ki > 7700 nM
|
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CP0485162
|
9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-ol
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|
C19H29NO3
|
5
|
| 1 |
IC50 = 28.1 nM
|
|
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| 2 |
Kd = 71 nM
|
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| 3 |
Ki = 70 nM
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| 4 |
Ki = 152 nM
|
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| 5 |
Ki > 10000 nM
|
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CP0262735
|
ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-(4-fluorophenyl)piperidine-3-carboxylate
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|
C24H26FN3O4
|
4
|
| 1 |
IC50 = 39.4 nM
|
|
|
| 2 |
Ki = 74 nM
|
|
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| 3 |
Ki = 161 nM
|
|
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| 4 |
Ki > 7400 nM
|
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|
|
CP0391815
|
ethyl (3S,4R)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-(4-fluorophenyl)piperidine-3-carboxylate
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|
C24H26FN3O4
|
4
|
| 1 |
IC50 = 85.5 nM
|
|
|
| 2 |
Ki = 176 nM
|
|
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| 3 |
Ki = 750 nM
|
|
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| 4 |
Ki = 1150 nM
|
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|
CP0370076
|
ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-thiophen-2-ylpiperidine-3-carboxylate
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|
C22H25N3O4S
|
4
|
| 1 |
IC50 = 101 nM
|
|
|
| 2 |
Ki = 450 nM
|
|
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| 3 |
Ki = 900 nM
|
|
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| 4 |
Ki = 6160 nM
|
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CP0368363
|
ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-[3-(trifluoromethyl)phenyl]piperidine-3-carboxylate
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|
C25H26F3N3O4
|
4
|
| 1 |
IC50 = 125 nM
|
|
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| 2 |
Ki = 350 nM
|
|
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| 3 |
Ki = 990 nM
|
|
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| 4 |
Ki > 10000 nM
|
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|
|
CP0329619
|
ethyl (3S,4S)-4-(2,3-dihydro-1,4-benzodioxin-5-yl)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]piperidine-3-carboxylate
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|
C26H29N3O6
|
4
|
| 1 |
IC50 = 142 nM
|
|
|
| 2 |
Ki = 652 nM
|
|
|
| 3 |
Ki = 700 nM
|
|
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| 4 |
Ki > 7900 nM
|
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CP0391814
|
2-ethyl-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol
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|
C21H33NO3
|
4
|
| 1 |
IC50 = 154 nM
|
|
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| 2 |
Ki = 64 nM
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| 3 |
Ki = 83 nM
|
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| 4 |
Ki = 1932 nM
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CP0055933
|
3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione
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|
C22H22FN3O3
|
4
|
| 1 |
IC50 = 180 nM
|
|
|
| 2 |
Ki = 77 nM
|
|
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| 3 |
Ki = 353 nM
|
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| 4 |
Ki = 1190 nM
|
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|
|
CP0001238
|
14C-5-hydroxy tryptamine creatinine disulfate
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|
C10H12N2O
|
3
|
| 1 |
IC50 = 1430 nM
|
|
|
| 2 |
Ki = 2290 nM
|
|
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| 3 |
Ki = 7690 nM
|
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CP0391812
|
ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-(4-methylphenyl)piperidine-3-carboxylate
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|
C25H29N3O4
|
4
|
| 1 |
IC50 = 2700 nM
|
|
|
| 2 |
Ki = 452 nM
|
|
|
| 3 |
Ki > 10000 nM
|
|
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| 4 |
Ki > 9100 nM
|
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|
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CP0472846
|
ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylate
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|
C25H26F3N3O4
|
3
|
| 1 |
IC50 = 2900 nM
|
|
|
| 2 |
Ki = 720 nM
|
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| 3 |
Ki > 10000 nM
|
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|
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CP0468811
|
(R)Methyl-(1-methyl-2-phenyl-ethyl)-amine
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|
C10H15N
|
3
|
| 1 |
IC50 = 3620 nM
|
|
|
| 2 |
Ki = 6400 nM
|
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| 3 |
Ki = 24500 nM
|
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|
|
CP0011881
|
(-)-lobeline
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|
C22H27NO2
|
4
|
| 1 |
IC50 = 4200 nM
|
|
|
| 2 |
Ki = 1840 nM
|
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| 3 |
Ki = 1950 nM
|
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| 4 |
Ki > 10000 nM
|
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CP0329617
|
ethyl (3S,4S)-4-[4-(dimethylamino)phenyl]-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]piperidine-3-carboxylate
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|
C26H32N4O4
|
3
|
| 1 |
IC50 = 5800 nM
|
|
|
| 2 |
Ki = 1960 nM
|
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| 3 |
Ki > 10000 nM
|
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CP0329618
|
ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-(4-ethoxycarbonylphenyl)piperidine-3-carboxylate
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|
C27H31N3O6
|
3
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
Ki = 1660 nM
|
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| 3 |
Ki > 10000 nM
|
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CP0417151
|
ethyl (3S,4S)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-(4-phenylphenyl)piperidine-3-carboxylate
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|
C30H31N3O4
|
3
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
Ki = 3770 nM
|
|
|
| 3 |
Ki > 10000 nM
|
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|
|
CP0115748
|
ethyl 1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-(4-fluorophenyl)piperidine-3-carboxylate
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|
C24H26FN3O4
|
2
|
| 1 |
Kd = 93 nM
|
|
|
| 2 |
Ki = 290 nM
|
|
|
|
CP0391813
|
1,2-ditritioethyl (3R,4R)-1-[2-(2,4-dioxo-1H-quinazolin-3-yl)ethyl]-4-(4-fluorophenyl)piperidine-3-carboxylate
Show/Hide
|
C24H26FN3O4
|
1
|
| 1 |
Kd = 93 nM
|
|
|
