Brief Information of the Compound and Protein
Compound Name
(-)-reserpine
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PubChem ID
CID: 5770
SID: 16543090
Canonical SMILES
CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)c1cc(OC)c(OC)c(OC)c1
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Compound Formula C33H40N2O9
Compound Structure
Protein Name
Synaptic vesicular amine transporter
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC18 family of vesicular amine transporters
Uniprot ID
Q05940
Gene Name
SLC18A2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  5
1
IC50 = 13.2 nM
   TI
   LI
   LO
   TS
2
Kd = 8 nM
   TI
   LI
   LO
   TS
3
Ki = 5.26 nM
   TI
   LI
   LO
   TS
4
Ki = 410 nM
   TI
   LI
   LO
   TS
5
Ki = 630 nM
   TI
   LI
   LO
   TS