Brief Information of the Compound and Protein
Compound Name
9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-ol
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PubChem ID
CID: 123836
SID: 15420766
Canonical SMILES
COc1cc2CCN3CC(CC(C)C)C(O)CC3c2cc1OC
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Compound Formula C19H29NO3
Compound Structure
Protein Name
Synaptic vesicular amine transporter
Protein Classification
Transporter
>
Electrochemical transporter
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SLC superfamily of solute carriers
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SLC18 family of vesicular amine transporters
Uniprot ID
Q05940
Gene Name
SLC18A2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  5
1
IC50 = 28.1 nM
   TI
   LI
   LO
   TS
2
Kd = 71 nM
   TI
   LI
   LO
   TS
3
Ki = 70 nM
   TI
   LI
   LO
   TS
4
Ki = 152 nM
   TI
   LI
   LO
   TS
5
Ki > 10000 nM
   TI
   LI
   LO
   TS