Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT00948 , Prostaglandin E2 receptor EP2 subtype
Gene Name PTGER2
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P43116
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT00948
 
Compound ID Compound Name Compound Formula
CP0168917
Omidenepag
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C23H22N6O4S
 2
1
EC50 = 1.1 nM
   TI
   LI
   LO
   TS
2
IC50 = 10 nM
   TI
   LI
   LO
   TS
CP0847243
5-{(R)-1-[4-(1-Hydroxy-heptyl)-phenyl]-5-oxo-pyrrolidin-2-ylmethoxymethyl}-thiophene-2-carboxylic acid
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C24H31NO5S
 3
1
EC50 = 1.6 nM
   TI
   LI
   LO
   TS
2
Ki = 10 nM
   TI
   LI
   LO
   TS
3
Ki = 190 nM
   TI
   LI
   LO
   TS
CP0870431
5-(3-{(S)-1-[4-(1-Hydroxy-hexyl)-phenyl]-5-oxo-pyrrolidin-2-yl}-propyl)-thiophene-2-carboxylic acid
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C24H31NO4S
 2
1
EC50 = 1.6 nM
   TI
   LI
   LO
   TS
2
Ki = 15 nM
   TI
   LI
   LO
   TS
CP0394034
2-[[6-[[(4-pyridin-2-ylphenyl)methyl-pyridin-3-ylsulfonylamino]methyl]pyridin-2-yl]amino]acetic acid
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C25H23N5O4S
 1
1
EC50 = 1.6 nM
   TI
   LI
   LO
   TS
CP0870239
5-(3-((1R,2S)-2-(4-(1-hydroxyhexyl)phenyl)-5-oxocyclopentyl)propyl)thiophene-2-carboxylic acid
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C25H32O4S
 2
1
EC50 = 2 nM
   TI
   LI
   LO
   TS
2
Ki = 54 nM
   TI
   LI
   LO
   TS
CP0946462
(6-((Biphenyl-4-ylmethyl)(pyridin-3-ylsulfonyl)aminomethyl)-pyridin-2-ylamino)acetic Acid Hydrochloride
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C26H25ClN4O4S
 1
1
EC50 = 2 nM
   TI
   LI
   LO
   TS
CP0401695
2-[(2R,4aR,5S,6R,7aS)-6-hydroxy-5-[(2,3,4-trichlorophenoxy)methyl]-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C19H18Cl3NO5S
 1
1
EC50 = 2.3 nM
   TI
   LI
   LO
   TS
CP0401697
2-[(2R,4aR,5S,6R,7aS)-5-[(4-chloro-3,5-dimethylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C21H24ClNO5S
 1
1
EC50 = 2.3 nM
   TI
   LI
   LO
   TS
CP0468701
2-[[6-[[[4-(1-methylcyclopropyl)phenyl]methyl-pyridin-3-ylsulfonylamino]methyl]pyridin-2-yl]amino]acetic acid;hydrochloride
   Show/Hide
C24H27ClN4O4S
 1
1
EC50 = 2.6 nM
   TI
   LI
   LO
   TS
CP0539129
2-[[6-[[(4-tert-butylphenyl)methyl-(4-fluorophenyl)sulfonylamino]methyl]pyridin-2-yl]amino]acetic acid;hydrochloride
   Show/Hide
C25H29ClFN3O4S
 1
1
EC50 = 2.7 nM
   TI
   LI
   LO
   TS
CP0575238
2-[[6-[[(4-tert-butylphenyl)methyl-pyridin-2-ylsulfonylamino]methyl]pyridin-2-yl]amino]acetic acid;hydrochloride
   Show/Hide
C24H29ClN4O4S
 1
1
EC50 = 2.7 nM
   TI
   LI
   LO
   TS
CP0538158
2-[[6-[[(4-tert-butylphenyl)methyl-pyridin-3-ylsulfonylamino]methyl]pyridin-2-yl]amino]acetic acid;hydrochloride
   Show/Hide
C24H29ClN4O4S
 1
1
EC50 = 2.8 nM
   TI
   LI
   LO
   TS
CP0538161
2-[[6-[[1-benzothiophen-2-ylmethyl(pyridin-3-ylsulfonyl)amino]methyl]pyridin-2-yl]amino]acetic acid;hydrochloride
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C22H21ClN4O4S2
 1
1
EC50 = 3.4 nM
   TI
   LI
   LO
   TS
CP0401696
2-[(2R,4aR,5S,6R,7aS)-6-hydroxy-5-[(2,4,5-trichlorophenoxy)methyl]-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C19H18Cl3NO5S
 1
1
EC50 = 3.7 nM
   TI
   LI
   LO
   TS
CP0434757
2-[[6-[[benzenesulfonyl-[(4-tert-butylphenyl)methyl]amino]methyl]pyridin-2-yl]amino]acetic acid;hydrochloride
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C25H30ClN3O4S
 1
1
EC50 = 4.3 nM
   TI
   LI
   LO
   TS
CP0436871
2-[[6-[[(4-tert-butylphenyl)methyl-(4-chlorophenyl)sulfonylamino]methyl]pyridin-2-yl]amino]acetic acid;hydrochloride
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C25H29Cl2N3O4S
 1
1
EC50 = 4.4 nM
   TI
   LI
   LO
   TS
CP0482823
2-[[6-[[[4-(1-ethylcyclopropyl)phenyl]methyl-pyridin-3-ylsulfonylamino]methyl]pyridin-2-yl]amino]acetic acid
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C25H28N4O4S
 1
1
EC50 = 4.5 nM
   TI
   LI
   LO
   TS
CP0866241
5-(3-{(S)-1-[4-(1-Hydroxy-heptyl)-phenyl]-5-oxo-pyrrolidin-2-yl}-propyl)-thiophene-2-carboxylic acid
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C25H33NO4S
 2
1
EC50 = 5 nM
   TI
   LI
   LO
   TS
2
Ki = 8 nM
   TI
   LI
   LO
   TS
CP0440481
2-[[6-[[1-benzofuran-2-ylmethyl(pyridin-3-ylsulfonyl)amino]methyl]pyridin-2-yl]amino]acetic acid;hydrochloride
   Show/Hide
C22H21ClN4O5S
 1
1
EC50 = 5.6 nM
   TI
   LI
   LO
   TS
CP0468700
2-[[6-[[(4-tert-butylphenyl)methyl-(3-fluorophenyl)sulfonylamino]methyl]pyridin-2-yl]amino]acetic acid;hydrochloride
   Show/Hide
C25H29ClFN3O4S
 1
1
EC50 = 6.1 nM
   TI
   LI
   LO
   TS
CP0847236
5-{(R)-1-[4-(1-Hydroxy-hexyl)-phenyl]-5-oxo-pyrrolidin-2-ylmethoxymethyl}-thiophene-2-carboxylic acid
   Show/Hide
C23H29NO5S
 2
1
EC50 = 8 nM
   TI
   LI
   LO
   TS
2
Ki = 115 nM
   TI
   LI
   LO
   TS
CP0377164
2-[(2R,4aR,5S,6R,7aS)-6-hydroxy-5-[[3-(trifluoromethyl)phenoxy]methyl]-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C20H20F3NO5S
 1
1
EC50 = 9 nM
   TI
   LI
   LO
   TS
CP0377163
2-[(2R,4aR,5S,6R,7aS)-6-hydroxy-5-[[2-(trifluoromethyl)phenoxy]methyl]-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C20H20F3NO5S
 1
1
EC50 = 11 nM
   TI
   LI
   LO
   TS
CP0482824
2-[[6-[[[4-(1-ethylcyclobutyl)phenyl]methyl-pyridin-3-ylsulfonylamino]methyl]pyridin-2-yl]amino]acetic acid
   Show/Hide
C26H30N4O4S
 1
1
EC50 = 13 nM
   TI
   LI
   LO
   TS
CP0870434
7-((1R,2S,3R,5R)-3,5-dichloro-2-(4-(1-hydroxyhexyl)phenyl)cyclopentyl)hept-5-enoic acid
   Show/Hide
C24H34Cl2O3
 2
1
EC50 = 15 nM
   TI
   LI
   LO
   TS
2
Ki = 25 nM
   TI
   LI
   LO
   TS
CP0080235
4-(2-((R)-2-((S)-3-hydroxyhept-1-enyl)-5-oxopyrrolidin-1-yl)ethyl)benzoate
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C20H27NO4
 2
1
EC50 = 16 nM
   TI
   LI
   LO
   TS
2
Ki = 125.5 nM
   TI
   LI
   LO
   TS
CP0847237
5-{3-[(S)-1-(4-Hexanoyl-phenyl)-5-oxo-pyrrolidin-2-yl]-propyl}-thiophene-2-carboxylic acid
   Show/Hide
C24H29NO4S
 2
1
EC50 = 16 nM
   TI
   LI
   LO
   TS
2
Ki = 31 nM
   TI
   LI
   LO
   TS
CP0539128
C-533,536-02
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C25H27N2NaO5S
 2
1
EC50 = 17 nM
   TI
   LI
   LO
   TS
2
Ki = 16 nM
   TI
   LI
   LO
   TS
CP0466688
2-[[6-[[[4-(1-propan-2-ylcyclopropyl)phenyl]methyl-pyridin-3-ylsulfonylamino]methyl]pyridin-2-yl]amino]acetic acid
   Show/Hide
C26H30N4O4S
 1
1
EC50 = 18 nM
   TI
   LI
   LO
   TS
CP0458129
2-[[6-[[(4-tert-butylphenyl)methyl-(4-methoxyphenyl)sulfonylamino]methyl]pyridin-2-yl]amino]acetic acid;hydrochloride
   Show/Hide
C26H32ClN3O5S
 1
1
EC50 = 19 nM
   TI
   LI
   LO
   TS
CP0452767
4-(2-((R)-2-(3-methylocta-1,3-dienyl)-5-oxopyrrolidin-1-yl)ethyl)benzoic acid
   Show/Hide
C22H29NO3
 2
1
EC50 = 23 nM
   TI
   LI
   LO
   TS
2
Ki = 29 nM
   TI
   LI
   LO
   TS
CP0847242
5-[(R)-1-(4-tert-Butyl-phenyl)-5-oxo-pyrrolidin-2-ylmethoxymethyl]-thiophene-2-carboxylic acid
   Show/Hide
C21H25NO4S
 4
1
EC50 = 27 nM
   TI
   LI
   LO
   TS
2
EC50 = 1343 nM
   TI
   LI
   LO
   TS
3
Ki = 27 nM
   TI
   LI
   LO
   TS
4
Ki = 501 nM
   TI
   LI
   LO
   TS
CP0539130
2-[[6-[[(4-cyclohexylphenyl)methyl-pyridin-3-ylsulfonylamino]methyl]pyridin-2-yl]amino]acetic acid
   Show/Hide
C26H30N4O4S
 1
1
EC50 = 29 nM
   TI
   LI
   LO
   TS
CP0866746
7-((1R,2S,3R)-2-(4-hexanoylphenyl)-3-hydroxy-5-oxocyclopentyl)hept-5-enoic acid
   Show/Hide
C24H32O5
 2
1
EC50 = 31 nM
   TI
   LI
   LO
   TS
2
Ki = 111 nM
   TI
   LI
   LO
   TS
CP0899507
7-((1S,2S,3R,5R)-5-cyano-3-hydroxy-2-(4-(1-hydroxyhexyl)phenyl)cyclopentyl)hept-5-enoic acid
   Show/Hide
C25H35NO4
 2
1
EC50 = 34 nM
   TI
   LI
   LO
   TS
2
Ki = 1252 nM
   TI
   LI
   LO
   TS
CP0452766
4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrrolidin-1-yl)ethyl)benzoic acid
   Show/Hide
C22H29NO3
 2
1
EC50 = 35 nM
   TI
   LI
   LO
   TS
2
Ki = 60 nM
   TI
   LI
   LO
   TS
CP0901193
(6-((4'-Fluorobiphenyl-4-ylmethyl)(pyridin-3-ylsulfonyl)-aminomethyl)pyridin-2-ylamino)acetic Acid Hydrochloride
   Show/Hide
C26H24ClFN4O4S
 1
1
EC50 = 35 nM
   TI
   LI
   LO
   TS
CP0468695
2-[[6-[[pyridin-3-ylsulfonyl-[[4-(1,2,4-triazol-1-yl)phenyl]methyl]amino]methyl]pyridin-2-yl]amino]acetic acid
   Show/Hide
C22H21N7O4S
 1
1
EC50 = 43 nM
   TI
   LI
   LO
   TS
CP0394031
2-[[6-[[(4-tert-butylphenyl)methyl-(2-fluorophenyl)sulfonylamino]methyl]pyridin-2-yl]amino]acetic acid;hydrochloride
   Show/Hide
C25H29ClFN3O4S
 1
1
EC50 = 45 nM
   TI
   LI
   LO
   TS
CP0377162
2-[(2R,4aR,5S,6R,7aS)-6-hydroxy-5-[[3-(trifluoromethoxy)phenoxy]methyl]-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C20H20F3NO6S
 1
1
EC50 = 69 nM
   TI
   LI
   LO
   TS
CP0882301
(6-((4'-Chlorobiphenyl-4-ylmethyl)(pyridin-3-ylsulfonyl)-aminomethyl)pyridin-2-ylamino)acetic Acid Hydrochloride
   Show/Hide
C26H24Cl2N4O4S
 1
1
EC50 = 75 nM
   TI
   LI
   LO
   TS
CP0434756
3-[[6-[[(4-tert-butylphenyl)methyl-pyridin-3-ylsulfonylamino]methyl]pyridin-2-yl]amino]propanoic acid;hydrochloride
   Show/Hide
C25H31ClN4O4S
 1
1
EC50 = 83 nM
   TI
   LI
   LO
   TS
CP0458128
2-[[6-[[(4-tert-butylphenyl)methyl-methylsulfonylamino]methyl]pyridin-2-yl]amino]acetic acid;hydrochloride
   Show/Hide
C20H28ClN3O4S
 1
1
EC50 = 91 nM
   TI
   LI
   LO
   TS
CP0924067
7-((1R,2S,3R)-2-(4-tert-butylphenyl)-3-hydroxy-5-oxocyclopentyl)heptanoic acid
   Show/Hide
C22H32O4
 1
1
EC50 = 102 nM
   TI
   LI
   LO
   TS
CP0558990
2-[[6-[[(3-tert-butylphenyl)methyl-pyridin-3-ylsulfonylamino]methyl]pyridin-2-yl]amino]acetic acid;hydrochloride
   Show/Hide
C24H29ClN4O4S
 1
1
EC50 = 109 nM
   TI
   LI
   LO
   TS
CP0866254
7-((1R,2S,3R,5R)-2-(4-tert-butylphenyl)-5-chloro-3-hydroxycyclopentyl)hept-5-enoic acid
   Show/Hide
C22H31ClO3
 1
1
EC50 = 118 nM
   TI
   LI
   LO
   TS
CP0574584
2-[[6-[[5-phenylpentyl(pyridin-3-ylsulfonyl)amino]methyl]pyridin-2-yl]amino]acetic acid;hydrochloride
   Show/Hide
C24H29ClN4O4S
 1
1
EC50 = 118 nM
   TI
   LI
   LO
   TS
CP0394032
2-[[6-[[pyridin-3-ylsulfonyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]pyridin-2-yl]amino]acetic acid;hydrochloride
   Show/Hide
C21H20ClF3N4O4S
 1
1
EC50 = 119 nM
   TI
   LI
   LO
   TS
CP0885328
5-[(R)-1-(4-tert-Butyl-phenyl)-5-oxo-pyrrolidin-2-ylmethoxymethyl]-furan-2-carboxylic acid
   Show/Hide
C21H25NO5
 4
1
EC50 = 189 nM
   TI
   LI
   LO
   TS
2
EC50 = 442 nM
   TI
   LI
   LO
   TS
3
Ki = 189 nM
   TI
   LI
   LO
   TS
4
Ki = 4000 nM
   TI
   LI
   LO
   TS
CP0483781
4-(2-((R)-2-(octa-1,3-dienyl)-5-oxopyrrolidin-1-yl)ethyl)benzoic acid
   Show/Hide
C21H27NO3
 2
1
EC50 = 197 nM
   TI
   LI
   LO
   TS
2
Ki = 88 nM
   TI
   LI
   LO
   TS
CP0380277
2-[(2R,4aR,5S,6R,7aS)-5-[(2-chlorophenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C19H20ClNO5S
 1
1
EC50 = 203 nM
   TI
   LI
   LO
   TS
CP0850988
5-{(R)-1-[4-(1-Hydroxy-pentyl)-phenyl]-5-oxo-pyrrolidin-2-ylmethoxymethyl}-thiophene-2-carboxylic acid
   Show/Hide
C22H27NO5S
 2
1
EC50 = 212 nM
   TI
   LI
   LO
   TS
2
Ki = 387 nM
   TI
   LI
   LO
   TS
CP0847238
5-[(R)-1-(4-Hexanoyl-phenyl)-5-oxo-pyrrolidin-2-ylmethoxymethyl]-thiophene-2-carboxylic acid
   Show/Hide
C23H27NO5S
 2
1
EC50 = 215 nM
   TI
   LI
   LO
   TS
2
Ki = 163 nM
   TI
   LI
   LO
   TS
CP0464527
4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrrolidin-1-yl)ethyl)benzoic acid
   Show/Hide
C22H29NO3
 2
1
EC50 = 222 nM
   TI
   LI
   LO
   TS
2
Ki = 134 nM
   TI
   LI
   LO
   TS
CP0895715
5-(3-((2R)-1-(4-(1-hydroxyhexyl)phenyl)-5-oxopyrrolidin-2-yl)allyl)thiophene-2-carboxylic acid
   Show/Hide
C24H29NO4S
 2
1
EC50 = 226 nM
   TI
   LI
   LO
   TS
2
Ki = 1382 nM
   TI
   LI
   LO
   TS
CP0866433
7-((1R,2S,3R,5R)-2-(4-tert-butylphenyl)-5-chloro-3-hydroxycyclopentyl)heptanoic acid
   Show/Hide
C22H33ClO3
 1
1
EC50 = 264 nM
   TI
   LI
   LO
   TS
CP0863098
2-(3-(((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(3-(hydroxy(1-propylcyclobutyl)methyl)phenyl)cyclopentyl)methyl)phenoxy)acetic acid
   Show/Hide
C28H35ClO5
 2
1
EC50 = 266 nM
   TI
   LI
   LO
   TS
2
IC50 = 5200 nM
   TI
   LI
   LO
   TS
CP0387031
2-[[6-[[(4-tert-butylphenyl)methyl-pyridin-3-ylsulfonylamino]methyl]pyridin-2-yl]-methylamino]acetic acid;hydrochloride
   Show/Hide
C25H31ClN4O4S
 1
1
EC50 = 283 nM
   TI
   LI
   LO
   TS
CP0174264
7-[(1R,2S)-2-[4-(1-hydroxyhexyl)phenyl]-5-oxocyclopentyl]heptanoic acid
   Show/Hide
C24H36O4
 2
1
EC50 = 284 nM
   TI
   LI
   LO
   TS
2
Ki = 871 nM
   TI
   LI
   LO
   TS
CP0538160
2-[[6-[[(4-pyridazin-4-ylphenyl)methyl-pyridin-3-ylsulfonylamino]methyl]pyridin-2-yl]amino]acetic acid;hydrochloride
   Show/Hide
C24H23ClN6O4S
 1
1
EC50 = 307 nM
   TI
   LI
   LO
   TS
CP0869429
7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(3-(hydroxy(1-propylcyclobutyl)methyl)phenyl)cyclopentyl)hept-5-enoic acid
   Show/Hide
C26H37ClO4
 1
1
EC50 = 322 nM
   TI
   LI
   LO
   TS
CP0888285
7-((1R,2S)-2-(4-(2-hydroxyhexyl)phenyl)-5-oxocyclopentyl)heptanoic acid
   Show/Hide
C24H36O4
 2
1
EC50 = 343 nM
   TI
   LI
   LO
   TS
2
Ki = 700 nM
   TI
   LI
   LO
   TS
CP0055947
(15S)-prostaglandin E2
   Show/Hide
C20H32O5
 5
1
EC50 = 346 nM
   TI
   LI
   LO
   TS
2
IC50 = 2.6 nM
   TI
   LI
   LO
   TS
3
IC50 = 4 nM
   TI
   LI
   LO
   TS
4
Ki = 1.03 nM
   TI
   LI
   LO
   TS
5
Ki = 4.9 nM
   TI
   LI
   LO
   TS
CP0558989
2-[[4-[[(4-tert-butylphenyl)methyl-pyridin-3-ylsulfonylamino]methyl]-1,3-thiazol-2-yl]amino]acetic acid;hydrochloride
   Show/Hide
C22H27ClN4O4S2
 1
1
EC50 = 360 nM
   TI
   LI
   LO
   TS
CP0850987
5-{(R)-1-[4-(1-Hydroxy-hexyl)-phenyl]-5-oxo-pyrrolidin-2-ylmethoxymethyl}-furan-2-carboxylic acid
   Show/Hide
C23H29NO6
 2
1
EC50 = 388 nM
   TI
   LI
   LO
   TS
2
Ki = 2028 nM
   TI
   LI
   LO
   TS
CP0866434
7-((1R,2S,3R,5R)-5-chloro-2-(4-(cyclohexyl(hydroxy)methyl)phenyl)-3-hydroxycyclopentyl)hept-5-enoic acid
   Show/Hide
C25H35ClO4
 1
1
EC50 = 392 nM
   TI
   LI
   LO
   TS
CP0866283
7-((1R,2S,3R)-3-hydroxy-2-(1-hydroxy-2,3-dihydro-1H-inden-5-yl)-5-oxocyclopentyl)hept-5-enoic acid
   Show/Hide
C21H26O5
 2
1
EC50 = 405 nM
   TI
   LI
   LO
   TS
2
IC50 = 2281 nM
   TI
   LI
   LO
   TS
CP0847234
5-{(R)-1-[4-(1-Hydroxy-butyl)-phenyl]-5-oxo-pyrrolidin-2-ylmethoxymethyl}-thiophene-2-carboxylic acid
   Show/Hide
C21H25NO5S
 2
1
EC50 = 426 nM
   TI
   LI
   LO
   TS
2
Ki = 1639 nM
   TI
   LI
   LO
   TS
CP0866287
7-((1R,2S,3S,5R)-3,5-dichloro-2-(4-(1-hydroxyhexyl)phenyl)cyclopentyl)hept-5-enoic acid
   Show/Hide
C24H34Cl2O3
 2
1
EC50 = 427 nM
   TI
   LI
   LO
   TS
2
Ki = 504 nM
   TI
   LI
   LO
   TS
CP0856816
7-((1R,2S,3R)-2-(4-(cyclohexyl(hydroxy)methyl)phenyl)-3-hydroxy-5-oxocyclopentyl)heptanoic acid
   Show/Hide
C25H36O5
 1
1
EC50 = 450 nM
   TI
   LI
   LO
   TS
CP0866427
7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(1-hydroxy-2-methylpropyl)phenyl)cyclopentyl)hept-5-enoic acid
   Show/Hide
C22H31ClO4
 1
1
EC50 = 497 nM
   TI
   LI
   LO
   TS
CP0852835
7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(1-hydroxycyclobutyl)phenyl)cyclopentyl)hept-5-enoic acid
   Show/Hide
C22H29ClO4
 1
1
EC50 = 513 nM
   TI
   LI
   LO
   TS
CP0866768
7-((1R,2S,3R)-3-hydroxy-2-(4-(1-hydroxy-2-methylpropan-2-yl)phenyl)-5-oxocyclopentyl)heptanoic acid
   Show/Hide
C22H32O5
 2
1
EC50 = 526 nM
   TI
   LI
   LO
   TS
2
IC50 = 18735 nM
   TI
   LI
   LO
   TS
CP0852857
7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(1-hydroxy-2,3-dihydro-1H-inden-5-yl)cyclopentyl)heptanoic acid
   Show/Hide
C21H29ClO4
 2
1
EC50 = 529 nM
   TI
   LI
   LO
   TS
2
IC50 = 13139 nM
   TI
   LI
   LO
   TS
CP0852840
7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(3-(hydroxy(1-propylcyclobutyl)methyl)phenyl)cyclopentyl)heptanoic acid
   Show/Hide
C26H39ClO4
 1
1
EC50 = 546 nM
   TI
   LI
   LO
   TS
CP0552130
2-[[6-[[(4-tert-butylphenyl)methyl-(3-chlorophenyl)sulfonylamino]methyl]pyridin-2-yl]amino]acetic acid;hydrochloride
   Show/Hide
C25H29Cl2N3O4S
 1
1
EC50 = 620 nM
   TI
   LI
   LO
   TS
CP0866252
7-((1R,2S,3R)-3-hydroxy-2-(3-(hydroxy(1-propylcyclobutyl)methyl)phenyl)-5-oxocyclopentyl)heptanoic acid
   Show/Hide
C26H38O5
 1
1
EC50 = 635 nM
   TI
   LI
   LO
   TS
CP0468691
2-[[6-[[(4-tert-butylcyclohexyl)methyl-pyridin-3-ylsulfonylamino]methyl]pyridin-2-yl]amino]acetic acid;hydrochloride
   Show/Hide
C24H35ClN4O4S
 1
1
EC50 = 649 nM
   TI
   LI
   LO
   TS
CP0895714
7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(1-hydroxy-2-methylpropan-2-yl)phenyl)cyclopentyl)heptanoic acid
   Show/Hide
C22H33ClO4
 2
1
EC50 = 708 nM
   TI
   LI
   LO
   TS
2
IC50 = 8950 nM
   TI
   LI
   LO
   TS
CP0866243
4-{(R)-1-[4-(1-Hydroxy-hexyl)-phenyl]-5-oxo-pyrrolidin-2-ylmethoxy}-benzoic acid
   Show/Hide
C24H29NO5
 2
1
EC50 = 728 nM
   TI
   LI
   LO
   TS
2
Ki = 22726 nM
   TI
   LI
   LO
   TS
CP0900745
7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(1-hydroxycyclobutyl)phenyl)cyclopentyl)heptanoic acid
   Show/Hide
C22H31ClO4
 1
1
EC50 = 743 nM
   TI
   LI
   LO
   TS
CP0869414
7-((1R,2R,5S)-2-chloro-5-(5-(1-hydroxyhexyl)thiophen-2-yl)cyclopentyl)heptanoic acid
   Show/Hide
C22H35ClO3S
 2
1
EC50 = 769 nM
   TI
   LI
   LO
   TS
2
Ki = 600 nM
   TI
   LI
   LO
   TS
CP0888315
7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(1-hydroxy-2,2-dimethylpropyl)phenyl)cyclopentyl)hept-5-enoic acid
   Show/Hide
C23H33ClO4
 2
1
EC50 = 779 nM
   TI
   LI
   LO
   TS
2
IC50 = 1537 nM
   TI
   LI
   LO
   TS
CP0938030
7-((1R,2S,3R,5R)-5-chloro-2-(2,3-dihydro-1H-inden-5-yl)-3-hydroxycyclopentyl)heptanoic acid
   Show/Hide
C21H29ClO3
 2
1
EC50 = 818 nM
   TI
   LI
   LO
   TS
2
IC50 = 6251 nM
   TI
   LI
   LO
   TS
CP0866431
methyl 7-((1R,2S,3R)-2-(4-tert-butylphenyl)-3-hydroxy-5-oxocyclopentyl)heptanoate
   Show/Hide
C23H34O4
 1
1
EC50 = 936 nM
   TI
   LI
   LO
   TS
CP0852855
7-((1R,2S)-2-(4-(1-hydroxyhexyl)phenyl)-5-oxocyclopentyl)hept-5-enoic acid
   Show/Hide
C24H34O4
 2
1
EC50 = 1011 nM
   TI
   LI
   LO
   TS
2
Ki = 700 nM
   TI
   LI
   LO
   TS
CP0866286
7-((1R,2S)-2-(4-tert-butylphenyl)-5-oxocyclopentyl)hept-5-enoic acid
   Show/Hide
C22H30O3
 1
1
EC50 = 1050 nM
   TI
   LI
   LO
   TS
CP0847240
5-{(R)-1-[4-(1-Hydroxy-2-phenyl-ethyl)-phenyl]-5-oxo-pyrrolidin-2-ylmethoxymethyl}-furan-2-carboxylic acid
   Show/Hide
C25H25NO6
 2
1
EC50 = 1228 nM
   TI
   LI
   LO
   TS
2
Ki = 2293 nM
   TI
   LI
   LO
   TS
CP0856827
7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(1-hydroxy-2,2-dimethylpropyl)phenyl)cyclopentyl)heptanoic acid
   Show/Hide
C23H35ClO4
 2
1
EC50 = 1265 nM
   TI
   LI
   LO
   TS
2
IC50 = 3630 nM
   TI
   LI
   LO
   TS
CP0921736
7-((1R,2R,5S)-2-chloro-5-(4-(1-hydroxypentyl)phenyl)cyclopentyl)heptanoic acid
   Show/Hide
C23H35ClO3
 2
1
EC50 = 1409 nM
   TI
   LI
   LO
   TS
2
Ki = 1400 nM
   TI
   LI
   LO
   TS
CP0423796
4-[2-[3,5-dichloro-2-(3-hydroxyoctyl)-6-oxopyridin-1-yl]ethyl]benzoic acid
   Show/Hide
C22H27Cl2NO4
 1
1
EC50 = 1500 nM
   TI
   LI
   LO
   TS
CP0863099
2-(4-((2S,3R,5R)-5-chloro-2-(4-(cyclohexyl(hydroxy)methyl)phenyl)-3-hydroxycyclopentyl)but-2-ynyloxy)acetic acid
   Show/Hide
C24H31ClO5
 1
1
EC50 = 1550 nM
   TI
   LI
   LO
   TS
CP0870234
7-((1R,2S)-2-(4-((R)-cyclohexyl(hydroxy)methyl)phenyl)-5-oxocyclopentyl)hept-5-enoic acid
   Show/Hide
C25H34O4
 1
1
EC50 = 1640 nM
   TI
   LI
   LO
   TS
CP0866304
7-((1R,2S,3R)-2-(4-tert-butylphenyl)-3-hydroxy-5-oxocyclopentyl)hept-5-enoic acid
   Show/Hide
C22H30O4
 1
1
EC50 = 1709 nM
   TI
   LI
   LO
   TS
CP0847239
5-{(R)-1-[4-(1-Hydroxy-propyl)-phenyl]-5-oxo-pyrrolidin-2-ylmethoxymethyl}-thiophene-2-carboxylic acid
   Show/Hide
C20H23NO5S
 2
1
EC50 = 1812 nM
   TI
   LI
   LO
   TS
2
Ki = 5731 nM
   TI
   LI
   LO
   TS
CP0866249
7-((1R,2S)-2-(4-(cyclohexyl(hydroxy)methyl)phenyl)-5-oxocyclopentyl)hept-5-enoic acid
   Show/Hide
C25H34O4
 1
1
EC50 = 2101 nM
   TI
   LI
   LO
   TS
CP0856833
methyl 7-((1R,2S)-2-(4-(1-hydroxyhexyl)phenyl)-5-oxocyclopentyl)heptanoate
   Show/Hide
C25H38O4
 2
1
EC50 = 2162 nM
   TI
   LI
   LO
   TS
2
Ki = 4677 nM
   TI
   LI
   LO
   TS
CP0870418
7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(hydroxy(1-propylcyclobutyl)methyl)phenyl)cyclopentyl)hept-5-enoic acid
   Show/Hide
C26H37ClO4
 1
1
EC50 = 2270 nM
   TI
   LI
   LO
   TS
CP0870435
7-((1R,2S)-2-(3-((R)-hydroxy(1-propylcyclobutyl)methyl)phenyl)-5-oxocyclopentyl)hept-5-enoic acid
   Show/Hide
C26H36O4
 1
1
EC50 = 2657 nM
   TI
   LI
   LO
   TS
CP0866258
7-((1R,2S,3R,5R)-5-chloro-2-(4-(cyclohexyl(hydroxy)methyl)phenyl)-3-hydroxycyclopentyl)heptanoic acid
   Show/Hide
C25H37ClO4
 1
1
EC50 = 2813 nM
   TI
   LI
   LO
   TS
CP0866395
7-((1R,2S,3R)-3-hydroxy-5-oxo-2-p-tolylcyclopentyl)heptanoic acid
   Show/Hide
C19H26O4
 1
1
EC50 = 3128 nM
   TI
   LI
   LO
   TS
CP0888298
7-((1R,2S)-2-(3-(hydroxy(1-propylcyclobutyl)methyl)phenyl)-5-oxocyclopentyl)heptanoic acid
   Show/Hide
C26H38O4
 1
1
EC50 = 3407 nM
   TI
   LI
   LO
   TS
CP0852831
7-((1R,2S,3R,5R)-5-chloro-2-(4-(cyclohexylmethyl)phenyl)-3-hydroxycyclopentyl)heptanoic acid
   Show/Hide
C25H37ClO3
 1
1
EC50 = 3445 nM
   TI
   LI
   LO
   TS
CP0856836
7-((1R,2S,3R)-3-hydroxy-2-(3-(hydroxy(1-propylcyclobutyl)methyl)phenyl)-5-oxocyclopentyl)hept-5-enoic acid
   Show/Hide
C26H36O5
 1
1
EC50 = 3723 nM
   TI
   LI
   LO
   TS
CP0866278
2-(4-((1R,2S,3R,5R)-5-chloro-2-(4-(cyclohexyl(hydroxy)methyl)phenyl)-3-hydroxycyclopentyl)but-2-enyloxy)acetic acid
   Show/Hide
C24H33ClO5
 1
1
EC50 = 3844 nM
   TI
   LI
   LO
   TS
CP0866744
7-[(S)-1-(4-tert-Butyl-phenyl)-5-oxo-pyrrolidin-2-yl]-heptanoic acid
   Show/Hide
C21H31NO3
 2
1
EC50 = 4121 nM
   TI
   LI
   LO
   TS
2
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0380281
2-[(2R,4aR,5S,6R,7aS)-6-hydroxy-5-[[4-(trifluoromethoxy)phenoxy]methyl]-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C20H20F3NO6S
 1
1
EC50 = 4500 nM
   TI
   LI
   LO
   TS
CP0437308
4-[2-[3,5-dichloro-2-[(E)-3-hydroxy-3-methyloct-1-enyl]-6-oxopyridin-1-yl]ethyl]benzoic acid
   Show/Hide
C23H27Cl2NO4
 1
1
EC50 = 4700 nM
   TI
   LI
   LO
   TS
CP0957655
7-((5S)-5-(4-(1-hydroxyhexyl)phenyl)cyclopent-1-enyl)heptanoic acid
   Show/Hide
C24H36O3
 2
1
EC50 = 4877 nM
   TI
   LI
   LO
   TS
2
Ki = 2811 nM
   TI
   LI
   LO
   TS
CP0866285
methyl 7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(1-hydroxy-2,2-dimethylpropyl)phenyl)cyclopentyl)heptanoate
   Show/Hide
C24H37ClO4
 1
1
EC50 = 4995 nM
   TI
   LI
   LO
   TS
CP0888286
methyl 7-((1R,2R,5S)-2-chloro-5-(5-(1-hydroxyhexyl)thiophen-2-yl)cyclopentyl)heptanoate
   Show/Hide
C23H37ClO3S
 2
1
EC50 = 7100 nM
   TI
   LI
   LO
   TS
2
Ki = 7100 nM
   TI
   LI
   LO
   TS
CP0870416
5-{(R)-1-[4-(1-Hydroxy-2-methyl-propyl)-phenyl]-5-oxo-pyrrolidin-2-ylmethoxymethyl}-furan-2-carboxylic acid
   Show/Hide
C21H25NO6
 2
1
EC50 = 7669 nM
   TI
   LI
   LO
   TS
2
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0457559
4-(2-((R)-2-oxo-5-(4-phenylpenta-1,3-dienyl)pyrrolidin-1-yl)ethyl)benzoic acid
   Show/Hide
C24H25NO3
 2
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
2
Ki = 749 nM
   TI
   LI
   LO
   TS
CP0380278
2-[(2R,4aR,5S,6R,7aS)-6-hydroxy-5-(phenoxymethyl)-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C19H21NO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0380280
2-[(2R,4aR,5S,6R,7aS)-5-[(4-chlorophenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C19H20ClNO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0391092
2-[(2R,4aR,5S,6R,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-oxazole-4-carboxylic acid
   Show/Hide
C20H22ClNO6
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0391098
4-[(2R,4aR,5S,6R,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]thiophene-2-carboxylic acid
   Show/Hide
C21H23ClO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0401698
2-[(2R,4aR,5S,6S,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-methoxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C21H24ClNO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0401699
2-[(2R,4aR,5S,6R,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C20H22ClNO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0401700
2-[(2R,4aR,5S,6S,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C20H22ClNO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0401702
2-[(2R,4aR,5S,6S,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-fluoro-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C20H21ClFNO4S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0407410
4-[(2R,4aR,5S,6R,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]furan-2-carboxylic acid
   Show/Hide
C21H23ClO6
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0407431
2-[(2R,4aR,5S,6R,7aS)-5-[(4-chloro-3-methoxyphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C20H22ClNO6S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0414542
2-[(2R,4aR,5S,6R,7aS)-5-[(4-chloro-3-propan-2-ylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C22H26ClNO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0414599
2-[(2R,4aR,5S,6R,7aS)-5-[(3,4-dimethylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C21H25NO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0434442
2-[(2R,4aR,5S,6R,7aS)-5-[(4-chloro-3-ethylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C21H24ClNO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0434444
5-[(2R,4aR,5S,6R,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]furan-2-carboxylic acid
   Show/Hide
C21H23ClO6
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0483476
2-[(2R,4aR,5S,6R,7aS)-6-hydroxy-5-[[3-methyl-4-(trifluoromethyl)phenoxy]methyl]-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C21H22F3NO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0498080
2-[(2R,4aR,5S,6R,7aS)-5-[(3,4-dichlorophenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C19H19Cl2NO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0508797
2-[(2R,4aR,5S,6R,7aS)-5-[[4-chloro-3-(trifluoromethyl)phenoxy]methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C20H19ClF3NO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0377166
2-[(2R,4aR,5S,6R,7aS)-6-hydroxy-5-[(4-methylphenoxy)methyl]-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C20H23NO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0380283
2-[(2R,4aR,5S,6R,7aS)-5-[(2-fluorophenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C19H20FNO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0380284
2-[(2R,4aR,5S,6R,7aS)-5-[(3-chlorophenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C19H20ClNO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0409741
2-[(2R,4aR,5R,6R,7aS)-6-hydroxy-5-(5-phenoxypentyl)-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C23H29NO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0424625
2-[(2R,4aR,5S,6R,7aS)-6-hydroxy-5-[[4-(trifluoromethyl)phenoxy]methyl]-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C20H20F3NO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0428589
2-[(2R,4aR,5S,6R,7aS)-5-[(3-fluorophenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C19H20FNO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0452553
2-[(2R,4aR,5S,6R,7aS)-6-hydroxy-5-[(3-methylphenoxy)methyl]-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C20H23NO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0847318
2-{(2R,4aR,5R,6R,7aS)-6-hydroxy-5-[(1E)-3-phenoxy-1-propen-1-yl]octahydrocyclopenta[b]pyran-2-yl}-1,3-thiazole-4-carboxylic acid
   Show/Hide
C21H23NO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0847319
2-{(2R,4aR,5R,6R,7aS)-5-[(4-fluorophenoxy)methyl]-6-hydroxyoctahydrocyclopenta[b]pyran-2-yl}-1,3-thiazole-4-carboxylic acid
   Show/Hide
C19H20FNO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0847320
2-[(2R,4aR,5R,6R,7aS)-6-hydroxy-5-(2-phenoxyethyl)octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C20H23NO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0847322
2-{(2R,4aR,5R,6R,7aS)-6-hydroxy-5-[(1E)-5-phenoxy-1-penten-1-yl]octahydrocyclopenta[b]pyran-2-yl}-1,3-thiazole-4-carboxylic acid
   Show/Hide
C23H27NO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0862926
2-{(2R,4aR,5R,6R,7aS)-6-hydroxy-5-[(1E)-4-phenoxy-1-buten-1-yl]octahydrocyclopenta[b]pyran-2-yl}-1,3-thiazole-4-carboxylic acid
   Show/Hide
C22H25NO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0870958
2-[(2R,4aR,5R,6R,7aS)-6-hydroxy-5-(3-phenoxypropyl)octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
   Show/Hide
C21H25NO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0847233
3-{(R)-1-[4-(1-Hydroxy-hexyl)-phenyl]-5-oxo-pyrrolidin-2-ylmethoxymethyl}-benzoic acid
   Show/Hide
C25H31NO5
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0847241
3-[(R)-1-(4-tert-Butyl-phenyl)-5-oxo-pyrrolidin-2-ylmethoxymethyl]-benzoic acid
   Show/Hide
C23H27NO4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0852829
methyl 7-((1R,2S,3R,5R)-2-(4-tert-butylphenyl)-5-chloro-3-hydroxycyclopentyl)hept-5-enoate
   Show/Hide
C23H33ClO3
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0852830
methyl 7-((1R,2S,3R,5R)-2-(4-tert-butylphenyl)-5-chloro-3-hydroxycyclopentyl)heptanoate
   Show/Hide
C23H35ClO3
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0852841
methyl 7-((1R,2S,3R)-3-hydroxy-2-(3-(hydroxy(1-propylcyclobutyl)methyl)phenyl)-5-oxocyclopentyl)heptanoate
   Show/Hide
C27H40O5
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0856820
7-((1R,2S,3R)-3-hydroxy-2-(4-(1-hydroxycyclobutyl)phenyl)-5-oxocyclopentyl)heptanoic acid
   Show/Hide
C22H30O5
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0856822
methyl 7-((1R,2S,3R)-3-hydroxy-5-oxo-2-p-tolylcyclopentyl)heptanoate
   Show/Hide
C20H28O4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0863084
methyl 7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(3-(hydroxy(1-propylcyclobutyl)methyl)phenyl)cyclopentyl)hept-5-enoate
   Show/Hide
C27H39ClO4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0863766
methyl 7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(1-hydroxycyclobutyl)phenyl)cyclopentyl)hept-5-enoate
   Show/Hide
C23H31ClO4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0866245
7-((1R,2S)-2-(4-((R)-hydroxy(1-propylcyclobutyl)methyl)phenyl)-5-oxocyclopentyl)hept-5-enoic acid
   Show/Hide
C26H36O4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0866247
methyl 7-((1R,2S)-2-(4-((R)-cyclohexyl(hydroxy)methyl)phenyl)-5-oxocyclopentyl)hept-5-enoate
   Show/Hide
C26H36O4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0866253
N-ethyl-7-((1R,2S,3R)-3-hydroxy-2-(3-(hydroxy(1-propylcyclobutyl)methyl)phenyl)-5-oxocyclopentyl)hept-5-enamide
   Show/Hide
C26H37NO4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0866291
7-((1R,2S,3R)-2-(4-(cyclohexyl(hydroxy)methyl)phenyl)-3-hydroxy-5-oxocyclopentyl)hept-5-enoic acid
   Show/Hide
C25H34O5
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0866292
methyl 7-((1R,2S,3R)-2-(4-(cyclohexyl(hydroxy)methyl)phenyl)-3-hydroxy-5-oxocyclopentyl)heptanoate
   Show/Hide
C26H38O5
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0866303
7-((1R,2S,3R)-3-hydroxy-2-(4-(1-hydroxycyclobutyl)phenyl)-5-oxocyclopentyl)hept-5-enoic acid
   Show/Hide
C22H28O5
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0866394
methyl 7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(1-hydroxy-2-methylpropan-2-yl)phenyl)cyclopentyl)hept-5-enoate
   Show/Hide
C23H33ClO4
 2
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
2
IC50 = 48765 nM
   TI
   LI
   LO
   TS
CP0866430
methyl 7-((1R,2S,3R)-2-(4-tert-butylphenyl)-3-hydroxy-5-oxocyclopentyl)hept-5-enoate
   Show/Hide
C23H32O4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0870436
methyl 7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(1-hydroxycyclobutyl)phenyl)cyclopentyl)heptanoate
   Show/Hide
C23H33ClO4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0882892
methyl 7-((1R,2S,3R)-2-(2,3-dihydro-1H-inden-5-yl)-3-hydroxy-5-oxocyclopentyl)heptanoate
   Show/Hide
C22H30O4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0883084
5-[(R)-1-(4-tert-Butyl-phenyl)-5-oxo-pyrrolidin-2-ylmethoxy]-pentanoic acid
   Show/Hide
C20H29NO4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0888283
7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(hydroxymethyl)phenyl)cyclopentyl)heptanoic acid
   Show/Hide
C19H27ClO4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0888287
7-((1R,2S)-2-(4-(1-hydroxycyclobutyl)phenyl)-5-oxocyclopentyl)heptanoic acid
   Show/Hide
C22H30O4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0888294
methyl 7-((1R,2S,3R)-3-hydroxy-2-(3-(hydroxy(1-propylcyclobutyl)methyl)phenyl)-5-oxocyclopentyl)hept-5-enoate
   Show/Hide
C27H38O5
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0888316
methyl 7-((1R,2S)-2-(4-(cyclohexyl(hydroxy)methyl)phenyl)-5-oxocyclopentyl)heptanoate
   Show/Hide
C26H38O4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0899422
methyl 7-((1R,2S,3R)-2-(4-(cyclohexyl(hydroxy)methyl)phenyl)-3-hydroxy-5-oxocyclopentyl)hept-5-enoate
   Show/Hide
C26H36O5
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0900747
7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(1-hydroxy-2-methylpropyl)phenyl)cyclopentyl)heptanoic acid
   Show/Hide
C22H33ClO4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0920861
methyl 7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(hydroxymethyl)phenyl)cyclopentyl)hept-5-enoate
   Show/Hide
C20H27ClO4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0920862
methyl 7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(1-hydroxy-2-methylpropyl)phenyl)cyclopentyl)hept-5-enoate
   Show/Hide
C23H33ClO4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0928827
methyl 7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(1-hydroxy-2-methylpropan-2-yl)phenyl)cyclopentyl)heptanoate
   Show/Hide
C23H35ClO4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0966505
methyl 7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(1-hydroxy-2-methylpropyl)phenyl)cyclopentyl)heptanoate
   Show/Hide
C23H35ClO4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0420325
4-[2-[3,5-dichloro-2-[(E)-3-hydroxyoct-1-enyl]-6-oxopyridin-1-yl]ethyl]benzoic acid
   Show/Hide
C22H25Cl2NO4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0437306
7-[2-(3-hydroxyoctyl)-6-oxopyridin-1-yl]heptanoic acid
   Show/Hide
C20H33NO4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0487510
7-[3,5-dibromo-2-[(E)-3-hydroxyoct-1-enyl]-6-oxopyridin-1-yl]heptanoic acid
   Show/Hide
C20H29Br2NO4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0525833
7-[3,5-dichloro-2-[(E)-3-hydroxyoct-1-enyl]-6-oxopyridin-1-yl]heptanoic acid
   Show/Hide
C20H29Cl2NO4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0852856
methyl 7-((1R,2R,5S)-2-chloro-5-(4-(1-hydroxypentyl)phenyl)cyclopentyl)heptanoate
   Show/Hide
C24H37ClO3
 2
1
EC50 = 15000 nM
   TI
   LI
   LO
   TS
2
Ki = 15000 nM
   TI
   LI
   LO
   TS
CP0863699
methyl 7-((1R,2S)-2-(4-(1-hydroxyhexyl)phenyl)-5-oxocyclopentyl)hept-5-enoate
   Show/Hide
C25H36O4
 2
1
EC50 = 15000 nM
   TI
   LI
   LO
   TS
2
Ki = 15000 nM
   TI
   LI
   LO
   TS
CP0867160
methyl 7-((1R,2S)-2-(4-(2-hydroxyhexyl)phenyl)-5-oxocyclopentyl)heptanoate
   Show/Hide
C25H38O4
 2
1
EC50 = 15000 nM
   TI
   LI
   LO
   TS
2
Ki = 4600 nM
   TI
   LI
   LO
   TS
CP0926161
7-((1R,2R,5S)-2-fluoro-5-(4-(1-hydroxyhexyl)phenyl)cyclopentyl)heptanoic acid
   Show/Hide
C24H37FO3
 2
1
EC50 = 15000 nM
   TI
   LI
   LO
   TS
2
Ki = 600 nM
   TI
   LI
   LO
   TS
CP0947233
7-((1R,2R,5S)-2-chloro-5-(4-(1-hydroxyhexyl)phenyl)cyclopentyl)heptanoic acid
   Show/Hide
C24H37ClO3
 2
1
EC50 = 15000 nM
   TI
   LI
   LO
   TS
2
Ki = 1900 nM
   TI
   LI
   LO
   TS
CP0867141
2-(4-((1R,2S,3R,5R)-5-chloro-2-(4-(cyclohexyl(hydroxy)methyl)phenyl)-3-hydroxycyclopentyl)butoxy)acetic acid
   Show/Hide
C24H35ClO5
 1
1
EC50 = 20773 nM
   TI
   LI
   LO
   TS
CP0893966
7-((1R,2R,5S)-2-chloro-5-(4-(1-hydroxyhexyl)phenyl)cyclopentyl)heptan-1-ol
   Show/Hide
C24H39ClO2
 2
1
EC50 = 50000 nM
   TI
   LI
   LO
   TS
2
Ki = 50000 nM
   TI
   LI
   LO
   TS
CP0921737
methyl 7-((5S)-5-(4-(1-hydroxyhexyl)phenyl)cyclopent-1-enyl)heptanoate
   Show/Hide
C25H38O3
 2
1
EC50 = 50000 nM
   TI
   LI
   LO
   TS
2
Ki = 50000 nM
   TI
   LI
   LO
   TS
CP0926160
methyl 7-((1R,2S)-2-(3-(1-hydroxyhexyl)phenyl)-5-oxocyclopentyl)heptanoate
   Show/Hide
C25H38O4
 2
1
EC50 = 50000 nM
   TI
   LI
   LO
   TS
2
Ki = 50000 nM
   TI
   LI
   LO
   TS
CP0930472
7-((1R,2S)-2-(3-(1-hydroxyhexyl)phenyl)-5-oxocyclopentyl)heptanoic acid
   Show/Hide
C24H36O4
 2
1
EC50 = 50000 nM
   TI
   LI
   LO
   TS
2
Ki = 15000 nM
   TI
   LI
   LO
   TS
CP0942915
methyl 7-((1R,2R,5S)-2-fluoro-5-(4-(1-hydroxyhexyl)phenyl)cyclopentyl)heptanoate
   Show/Hide
C25H39FO3
 2
1
EC50 = 50000 nM
   TI
   LI
   LO
   TS
2
Ki = 50000 nM
   TI
   LI
   LO
   TS
CP0942917
methyl 7-((1R,2R,5S)-2-chloro-5-(4-(1-hydroxyhexyl)phenyl)cyclopentyl)heptanoate
   Show/Hide
C25H39ClO3
 2
1
EC50 = 50000 nM
   TI
   LI
   LO
   TS
2
Ki = 50000 nM
   TI
   LI
   LO
   TS
CP0866760
7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(1-hydroxy-2-methylpropan-2-yl)phenyl)cyclopentyl)hept-5-enoic acid
   Show/Hide
C22H31ClO4
 2
1
EC50 >= 173 nM
   TI
   LI
   LO
   TS
2
IC50 = 4185 nM
   TI
   LI
   LO
   TS
CP0394028
2-[[4-[[(4-tert-butylphenyl)methyl-pyridin-3-ylsulfonylamino]methyl]pyridin-2-yl]amino]acetic acid;hydrochloride
   Show/Hide
C24H29ClN4O4S
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0394030
2-[[2-[[(4-tert-butylphenyl)methyl-pyridin-3-ylsulfonylamino]methyl]pyridin-4-yl]amino]acetic acid;hydrochloride
   Show/Hide
C24H29ClN4O4S
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0468699
2-[6-[[(4-tert-butylphenyl)methyl-pyridin-3-ylsulfonylamino]methyl]indol-1-yl]acetic acid;2,2,2-trifluoroacetic acid
   Show/Hide
C29H30F3N3O6S
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0538159
2-[[6-[[(4-tert-butylphenyl)methyl-(2-chlorophenyl)sulfonylamino]methyl]pyridin-2-yl]amino]acetic acid;hydrochloride
   Show/Hide
C25H29Cl2N3O4S
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0882894
7-((1R,2S)-2-(4-(cyclohexyl(hydroxy)methyl)phenyl)-5-oxocyclopentyl)heptanoic acid
   Show/Hide
C25H36O4
 1
1
EC50 >= 2047 nM
   TI
   LI
   LO
   TS
CP0087804
ACT-129968
   Show/Hide
C24H19FN2O3
 1
1
IC50 = 2600 nM
   TI
   LI
   LO
   TS
CP0156868
2-[6-chloro-8-fluoro-2-(naphthalene-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
   Show/Hide
C24H18ClFN2O3
 1
1
IC50 = 2700 nM
   TI
   LI
   LO
   TS
CP0440482
De-117
   Show/Hide
C26H28N6O4S
 1
1
IC50 = 4180 nM
   TI
   LI
   LO
   TS
CP0471861
6-bromo-3-methyl-N-(2-pyridin-3-ylethyl)-2-thiophen-2-ylquinoline-4-carboxamide
   Show/Hide
C22H18BrN3OS
 1
1
IC50 = 4400 nM
   TI
   LI
   LO
   TS
CP0042409
2-[2-[4-(4-ethylphenyl)benzoyl]-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
   Show/Hide
C28H26N2O3
 1
1
IC50 = 6400 nM
   TI
   LI
   LO
   TS
CP0055416
2-[2-(naphthalene-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
   Show/Hide
C24H20N2O3
 1
1
IC50 = 6600 nM
   TI
   LI
   LO
   TS
CP0042410
2-[8-chloro-2-(naphthalene-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
   Show/Hide
C24H19ClN2O3
 1
1
IC50 = 7400 nM
   TI
   LI
   LO
   TS
CP0083568
2-[8-fluoro-2-(3-naphthalen-1-ylpropanoyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
   Show/Hide
C26H23FN2O3
 1
1
IC50 = 9500 nM
   TI
   LI
   LO
   TS
CP0045673
2-[2-(3-chlorobenzoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
   Show/Hide
C20H16ClFN2O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0055418
2-[6-chloro-2-(3-chlorobenzoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
   Show/Hide
C20H15Cl2FN2O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0055420
2-[2-(3-chlorobenzoyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
   Show/Hide
C20H17ClN2O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0055873
2-[8-fluoro-2-[2-(1H-indol-3-yl)acetyl]-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
   Show/Hide
C23H20FN3O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0055874
2-[8-fluoro-2-(thiophene-2-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
   Show/Hide
C18H15FN2O3S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0055877
2-[2-benzoyl-8-(trifluoromethyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
   Show/Hide
C21H17F3N2O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0070143
2-(2-benzoyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)acetic acid
   Show/Hide
C20H18N2O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0086399
2-[6-chloro-2-[4-(4-ethylphenyl)benzoyl]-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
   Show/Hide
C28H25ClN2O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0086409
2-[8-fluoro-2-(2-naphthalen-1-ylacetyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
   Show/Hide
C25H21FN2O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0130562
2-[8-methyl-2-(naphthalene-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
   Show/Hide
C25H22N2O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0261961
2-[2-(naphthalene-1-carbonyl)-8-(trifluoromethyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
   Show/Hide
C25H19F3N2O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0272414
US11149018, Example 34
   Show/Hide
C26H27BrClN3O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0863769
7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(hydroxymethyl)phenyl)cyclopentyl)hept-5-enoic acid
   Show/Hide
C19H25ClO4
 1
1
IC50 = 13150 nM
   TI
   LI
   LO
   TS
CP0060087
4-[(1S)-1-[[3-(trifluoromethyl)-5,6-dihydrobenzo[b][1]benzoxepine-10-carbonyl]amino]ethyl]benzoic acid
   Show/Hide
C25H20F3NO4
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0060088
4-[1-[[2-(trifluoromethyl)-5,6-dihydrobenzo[b][1]benzoxepine-10-carbonyl]amino]cyclopropyl]benzoic acid
   Show/Hide
C26H20F3NO4
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0060089
4-[1-[[3-(trifluoromethyl)-5,6-dihydrobenzo[b][1]benzoxepine-10-carbonyl]amino]cyclopropyl]benzoic acid
   Show/Hide
C26H20F3NO4
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0091346
4-[(1S)-1-[[2-(trifluoromethyl)-5,6-dihydrobenzo[b][1]benzoxepine-10-carbonyl]amino]ethyl]benzoic acid
   Show/Hide
C25H20F3NO4
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0092571
4-[(1S)-1-[[5-chloro-2-(4-fluorophenoxy)benzoyl]amino]ethyl]benzoic acid
   Show/Hide
C22H17ClFNO4
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0443957
4-[[(4-tert-butylphenyl)methyl-pyridin-3-ylsulfonylamino]methyl]-1-benzofuran-2-carboxylic acid
   Show/Hide
C26H26N2O5S
 1
1
Ki = 15 nM
   TI
   LI
   LO
   TS
CP0536164
4-(2-((R)-2-(4-(cyclopentylmethyl)penta-1,3-dienyl)-5-oxopyrrolidin-1-yl)ethyl)benzoic acid
   Show/Hide
C24H31NO3
 1
1
Ki = 60 nM
   TI
   LI
   LO
   TS
CP0343798
2-[(3R)-4-[(4-chlorophenyl)methyl]-7-fluoro-5-methylsulfonyl-2,3-dihydro-1H-cyclopenta[b]indol-3-yl]acetic acid
   Show/Hide
C21H19ClFNO4S
 1
1
Ki = 136 nM
   TI
   LI
   LO
   TS
CP0441655
4-[3-(2-Benzyloxy-phenyl)-propyl]-benzoic acid
   Show/Hide
C23H22O3
 1
1
Ki = 150 nM
   TI
   LI
   LO
   TS
CP0457560
4-(2-((R)-2-(4-methylhexa-1,3-dienyl)-5-oxopyrrolidin-1-yl)ethyl)benzoic acid
   Show/Hide
C20H25NO3
 1
1
Ki = 173 nM
   TI
   LI
   LO
   TS
CP0108218
(R)-2-(4-(4-chlorobenzyl)-5-acetyl-7-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid
   Show/Hide
C23H22ClNO5S
 1
1
Ki = 230 nM
   TI
   LI
   LO
   TS
CP0422463
1-(2,6-dimethoxyphenyl)-N-[[3-methyl-4-[6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-8H-pyrrolo[3,4-g]quinolin-7-yl]phenyl]methylsulfonyl]cyclopropane-1-carboxamide
   Show/Hide
C35H31F6N3O8S
 1
1
Ki = 300 nM
   TI
   LI
   LO
   TS
CP0372074
2-[(3R)-5-acetyl-4-[(4-chlorophenyl)methyl]-7-fluoro-2,3-dihydro-1H-cyclopenta[b]indol-3-yl]acetic acid
   Show/Hide
C22H19ClFNO3
 1
1
Ki = 310 nM
   TI
   LI
   LO
   TS
CP0426597
US9180116, 9C
   Show/Hide
C19H31F2NO4
 1
1
Ki = 329 nM
   TI
   LI
   LO
   TS
CP0041889
2-((R)-4-(4-chlorobenzyl)-5-(1-hydroxyethyl)-7-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid
   Show/Hide
C23H24ClNO5S
 1
1
Ki = 390 nM
   TI
   LI
   LO
   TS
CP0374187
2-[(3R)-5-bromo-4-[(4-chlorophenyl)methyl]-7-fluoro-2,3-dihydro-1H-cyclopenta[b]indol-3-yl]acetic acid
   Show/Hide
C20H16BrClFNO2
 1
1
Ki = 410 nM
   TI
   LI
   LO
   TS
CP0574605
6-[[(4-tert-butylphenyl)methyl-pyridin-3-ylsulfonylamino]methyl]-1-benzofuran-2-carboxylic acid
   Show/Hide
C26H26N2O5S
 1
1
Ki = 433 nM
   TI
   LI
   LO
   TS
CP0112284
CHEMBL3933704
   Show/Hide
C23H26FNO5
 1
1
Ki = 570 nM
   TI
   LI
   LO
   TS
CP0112283
APD-811
   Show/Hide
C23H26ClNO5
 1
1
Ki = 610 nM
   TI
   LI
   LO
   TS
CP0457558
4-[2-[(2R)-2-[(1Z,3E)-3-methylocta-1,3-dienyl]-5-oxopyrrolidin-1-yl]ethyl]benzoic acid
   Show/Hide
C22H29NO3
 1
1
Ki = 802 nM
   TI
   LI
   LO
   TS
CP0496137
(E)-3-(2-Benzyloxy-[1,1';3',1'']terphenyl-2''-yl)-acrylic acid
   Show/Hide
C28H22O3
 1
1
Ki = 830 nM
   TI
   LI
   LO
   TS
CP0847235
5-((E/Z)-3-{(R)-1-[4-(1-Hydroxy-hexyl)-phenyl]-5-oxo-pyrrolidin-2-yl}-allyl)-thiophene-2-carboxylic acid
   Show/Hide
C24H29NO4S
 1
1
Ki = 1382 nM
   TI
   LI
   LO
   TS
CP0144553
7-[(R)-2-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-oxo-pyrrolidin-1-yl]-heptanoic acid
   Show/Hide
C19H33NO4
 1
1
Ki = 1459 nM
   TI
   LI
   LO
   TS
CP0404585
3-[2-[3-(2-phenylmethoxyphenyl)phenyl]phenyl]-N-thiophen-2-ylsulfonylpropanamide
   Show/Hide
C32H27NO4S2
 1
1
Ki = 1600 nM
   TI
   LI
   LO
   TS
CP0464526
(R)-4-(2-(2-(4-methylpenta-1,3-dienyl)-5-oxopyrrolidin-1-yl)ethyl)benzoic acid
   Show/Hide
C19H23NO3
 1
1
Ki = 1850 nM
   TI
   LI
   LO
   TS
CP0393748
N-[[4-(5,9-diethoxy-6-oxo-8H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]-2-(2-methoxyphenyl)acetamide
   Show/Hide
C32H33N3O7S
 1
1
Ki = 1900 nM
   TI
   LI
   LO
   TS
CP0181173
2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl}-cyclopropanecarboxylic acid
   Show/Hide
C27H22O3S
 1
1
Ki = 2300 nM
   TI
   LI
   LO
   TS
CP0381724
3-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl}-propionic acid
   Show/Hide
C26H22O3S
 1
1
Ki = 2500 nM
   TI
   LI
   LO
   TS
CP0466746
2-[2-[5-(2-phenylmethoxyphenyl)thiophen-3-yl]anilino]acetic acid
   Show/Hide
C25H21NO3S
 1
1
Ki = 2500 nM
   TI
   LI
   LO
   TS
CP0404232
3-(2-Phenoxymethyl-[1,1';3',1'']terphenyl-2''-yl)-propionic acid
   Show/Hide
C28H24O3
 1
1
Ki = 2900 nM
   TI
   LI
   LO
   TS
CP0424293
3-{2-[4-(2-Benzyloxy-phenyl)-thiophen-2-yl]-phenyl}-propionic acid
   Show/Hide
C26H22O3S
 1
1
Ki = 2900 nM
   TI
   LI
   LO
   TS
CP0437614
4-(2-Benzyloxy-[1,1';3',1'']terphenyl-2''-yl)-butyric acid
   Show/Hide
C29H26O3
 1
1
Ki = 3500 nM
   TI
   LI
   LO
   TS
CP0406374
3-(2''-Benzyloxy-[1,1';3',1'']terphenyl-2-yl)-2-methyl-propionic acid
   Show/Hide
C29H26O3
 1
1
Ki = 3600 nM
   TI
   LI
   LO
   TS
CP0441093
(2''-Benzyloxy-[1,1';3',1'']terphenyl-2-yl)-acetic acid
   Show/Hide
C27H22O3
 1
1
Ki = 3600 nM
   TI
   LI
   LO
   TS
CP0436538
3-(2-Benzyloxy-[1,1';3',1'']terphenyl-2''-yl)-propionic acid
   Show/Hide
C28H24O3
 1
1
Ki = 3700 nM
   TI
   LI
   LO
   TS
CP0466770
3-{2-[5-(2-Benzyloxy-phenyl)-thiophen-2-yl]-phenyl}-propionic acid
   Show/Hide
C26H22O3S
 1
1
Ki = 4100 nM
   TI
   LI
   LO
   TS
CP0372972
3-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl}-butyric acid
   Show/Hide
C27H24O3S
 1
1
Ki = 4600 nM
   TI
   LI
   LO
   TS
CP0404532
3-[2''-(2,6-Dichloro-benzyloxy)-[1,1';3',1'']terphenyl-2-yl]-propionic acid
   Show/Hide
C28H22Cl2O3
 1
1
Ki = 4600 nM
   TI
   LI
   LO
   TS
CP0426640
US9180116, 2C
   Show/Hide
C21H31F2NO4
 1
1
Ki = 4971 nM
   TI
   LI
   LO
   TS
CP0430206
3-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl}-2-methyl-propionic acid
   Show/Hide
C27H24O3S
 1
1
Ki = 5500 nM
   TI
   LI
   LO
   TS
CP0415118
(E)-3-(3',4'-Dichloro-biphenyl-2-yl)-acrylic acid
   Show/Hide
C15H10Cl2O2
 1
1
Ki = 7500 nM
   TI
   LI
   LO
   TS
CP0277044
(E)-3-{2-[(E)-3-(2-Benzyloxy-3-methyl-phenyl)-allyl]-phenyl}-acrylic acid
   Show/Hide
C26H24O3
 1
1
Ki = 8100 nM
   TI
   LI
   LO
   TS
CP0381706
3-[1,1';3',1'']Terphenyl-2-yl-propionic acid
   Show/Hide
C21H18O2
 1
1
Ki = 8100 nM
   TI
   LI
   LO
   TS
CP0160939
(E)-3-[2-(3,4-dichlorophenyl)phenyl]-N-thiophen-2-ylsulfonylprop-2-enamide
   Show/Hide
C19H13Cl2NO3S2
 1
1
Ki = 10000 nM
   TI
   LI
   LO
   TS
CP0417632
7-[(2R)-2-[(E,3S,4S)-3-hydroxy-4-methylnon-1-en-6-ynyl]-5-oxopyrrolidin-1-yl]heptanoic acid
   Show/Hide
C21H33NO4
 1
1
Ki = 12173 nM
   TI
   LI
   LO
   TS
CP0388282
2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulfonamido)phenoxy)-3-methoxyphenyl)acetic acid
   Show/Hide
C26H26Cl2N2O7S
 1
1
Ki = 44000 nM
   TI
   LI
   LO
   TS
CP0404233
3-(4''-Benzyloxy-[1,1';3',1'']terphenyl-2-yl)-propionic acid
   Show/Hide
C28H24O3
 1
1
Ki > 97000 nM
   TI
   LI
   LO
   TS