General Information of the Compound
Compound ID
CP0574584
Compound Name
2-[[6-[[5-phenylpentyl(pyridin-3-ylsulfonyl)amino]methyl]pyridin-2-yl]amino]acetic acid;hydrochloride
    Show/Hide
Structure
Formula
C24H29ClN4O4S
Molecular Weight
505.04
Canonical SMILES
Cl.OC(=O)CNc1cccc(CN(CCCCCc2ccccc2)S(=O)(=O)c2cccnc2)n1
    Show/Hide
InChI
InChI=1S/C24H28N4O4S.ClH/c29-24(30)18-26-23-14-7-12-21(27-23)19-28(33(31,32)22-13-8-15-25-17-22)16-6-2-5-11-20-9-3-1-4-10-20;/h1,3-4,7-10,12-15,17H,2,5-6,11,16,18-19H2,(H,26,27)(H,29,30);1H
    Show/Hide
InChIKey
QQJZPADQYZVVOQ-UHFFFAOYSA-N
Physicochemical Property
logP
3.9988
Rotatable Bonds
13
Heavy Atom Count
34
Polar Areas
112.49
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 155550015
ChEMBL ID
CHEMBL4539881
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00948, Prostaglandin E2 receptor EP2 subtype
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 118 nM
   TI
   LI
   LO
   TS