Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(15S)-prostaglandin E2
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 PubChem ID
CID: 5280360
SID: 99431525
Canonical SMILES
CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
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Compound Formula C20H32O5
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E2 receptor EP2 subtype
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Prostanoid receptor
Uniprot ID
P43116
Gene Name
PTGER2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 1.9 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  5
1
EC50 = 346 nM
   TI
   LI
   LO
   TS
2
IC50 = 2.6 nM
   TI
   LI
   LO
   TS
3
IC50 = 4 nM
   TI
   LI
   LO
   TS
4
Ki = 1.03 nM
   TI
   LI
   LO
   TS
5
Ki = 4.9 nM
   TI
   LI
   LO
   TS
CL000314 HEK293T/17
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 9.3 nM
   TI
   LI
   LO
   TS
2
EC50 = 331 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 2.1 nM
2 IC50 = 2.2 nM
3 IC50 = 3.3 nM
4 IC50 = 37.7 nM
5 Ki = 1.7 nM
6 Ki = 4.9 nM
7 Ki = 38 nM