General Information of the Compound
Compound ID
CP0437614
Compound Name
4-(2-Benzyloxy-[1,1';3',1'']terphenyl-2''-yl)-butyric acid
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Structure
Formula
C29H26O3
Molecular Weight
422.524
Canonical SMILES
OC(=O)CCCc1ccccc1-c1cccc(c1)-c1ccccc1OCc1ccccc1
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InChI
InChI=1S/C29H26O3/c30-29(31)19-9-13-23-12-4-5-16-26(23)24-14-8-15-25(20-24)27-17-6-7-18-28(27)32-21-22-10-2-1-3-11-22/h1-8,10-12,14-18,20H,9,13,19,21H2,(H,30,31)
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InChIKey
LBBIICCAWUTPLB-UHFFFAOYSA-N
Physicochemical Property
logP
7.0069
Rotatable Bonds
9
Heavy Atom Count
32
Polar Areas
46.53
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 21362910
ChEMBL ID
CHEMBL125269
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01205, Prostaglandin E2 receptor EP1 subtype
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 11900 nM
   TI
   LI
   LO
   TS
Protein ID: PT00948, Prostaglandin E2 receptor EP2 subtype
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 3500 nM
   TI
   LI
   LO
   TS
Protein ID: PT01367, Prostaglandin E2 receptor EP3 subtype
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 590 nM
   TI
   LI
   LO
   TS
Protein ID: PT01534, Prostaglandin E2 receptor EP4 subtype
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 2000 nM
   TI
   LI
   LO
   TS