Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-HYDROXYTYRAMINE HYDROCHLORIDE
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 PubChem ID
CID: 681
SID: 15170929
Canonical SMILES
NCCc1ccc(O)c(O)c1
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Compound Formula C8H11NO2
Compound Structure
Protein Name
 Protein Info 
D(1A) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P21728
Gene Name
DRD1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 35 nM
   TI
   LI
   LO
   TS
2
EC50 = 39 nM
   TI
   LI
   LO
   TS
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
Kd = 2500 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 232 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  5
1
EC50 = 44 nM
   TI
   LI
   LO
   TS
2
EC50 = 120 nM
   TI
   LI
   LO
   TS
3
EC50 = 1400 nM
   TI
   LI
   LO
   TS
4
Ki = 130 nM
   TI
   LI
   LO
   TS
5
Ki = 12000 nM
   TI
   LI
   LO
   TS
CL000041 LTK-
 Cell Line Info 
Mus musculus (Mouse)  2
1
EC50 = 100 nM
   TI
   LI
   LO
   TS
2
Ki = 243 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 192 nM
2 Ki = 18200 nM