Brief Information of the Compound and Protein
| Compound Name |
N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
Platelet-derived growth factor receptor beta
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Protein Classification |
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase PDGFR family
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| Uniprot ID | Gene Name | PDGFRB |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Biochemical Assays
| 1 | IC50 = 2 nM | ||
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| 2 | IC50 = 3.9 nM | ||
| 3 | IC50 = 9 nM | ||
| 4 | IC50 = 10.5 nM | ||
| 5 | IC50 = 10.6 nM | ||
| 6 | IC50 = 55 nM | ||
| 7 | Kd = 0.075 nM | ||
| 8 | Kd = 0.2 nM | ||
| 9 | Kd = 0.21 nM | ||
| 10 | Ki = 8 nM | ||