Brief Information of the Compound and Protein
| Compound Name |
2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidin-2-yl}sulfanyl)acetic acid
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
Peroxisome proliferator-activated receptor alpha
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Protein Classification |
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group C
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Nuclear hormone receptor subfamily 1 group C member 1
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| Uniprot ID | Gene Name | PPARA |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Biochemical Assays
| 1 | EC50 = 740 nM | ||
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| 2 | EC50 = 12600 nM | ||
| 3 | EC50 = 13000 nM | ||
| 4 | EC50 = 15500 nM | ||
| 5 | EC50 = 29000 nM | ||
| 6 | IC50 = 10110 nM | ||
| 7 | Kd = 18.9 nM | ||
| 8 | Ki = 4130 nM | ||
| 9 | Ki = 4500 nM | ||