Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] sulfamate
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 PubChem ID
CID: 127676
SID: 57304377
Canonical SMILES
C[C@]12CC[C@H]3[C@@H](CCc4cc(OS(N)(=O)=O)ccc34)[C@@H]1CCC2=O
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Compound Formula C18H23NO4S
Compound Structure
Protein Name
 Protein Info 
Steryl-sulfatase
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
P08842
Gene Name
STS
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
2
IC50 = 30 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  4
1
IC50 = 1.6 nM
   TI
   LI
   LO
   TS
2
IC50 = 2.1 nM
   TI
   LI
   LO
   TS
3
IC50 = 2.4 nM
   TI
   LI
   LO
   TS
4
IC50 = 5.6 nM
   TI
   LI
   LO
   TS
CL000208 JEG-3
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 7600 nM
   TI
   LI
   LO
   TS
CL000083 MCF-7
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 0.065 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.83 nM
   TI
   LI
   LO
   TS
3
IC50 = 80 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.065 nM
2 IC50 = 8 nM
3 IC50 = 50 nM
4 IC50 = 56 nM
5 IC50 = 100 nM
6 IC50 = 500 nM
7 IC50 = 22000 nM
8 Ki = 670 nM
9 Km = 95000 nM