Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol
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 PubChem ID
CID: 6852376
Canonical SMILES
Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O
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Compound Formula C16H17NO2
Compound Structure
Protein Name
 Protein Info 
D(1A) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P21728
Gene Name
DRD1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 30 nM
   TI
   LI
   LO
   TS
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
Kd = 150 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 56 nM
   TI
   LI
   LO
   TS
CL000041 LTK-
 Cell Line Info 
Mus musculus (Mouse)  1
1
EC50 = 59 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1 nM
2 Ki = 73 nM
3 Ki = 320 nM