| Compound ID |
Compound Name |
Compound Formula |
|
CP0537180
|
(2S)-11-chloro-24-(3-hydroxycyclobutyl)-21-methyl-15-oxa-7,18,21,25,27,28-hexazapentacyclo[24.2.1.02,7.09,14.022,27]nonacosa-1(28),9(14),10,12,22,24,26(29)-heptaene-8,17-dione
Show/Hide
|
C27H31ClN6O4
|
2
|
| 1 |
EC50 = 0.27 nM
|
|
|
| 2 |
EC50 = 0.7 nM
|
|
|
|
CP0483669
|
(2S)-24-(azetidin-1-yl)-11-fluoro-21-methyl-15-oxa-7,18,21,25,27,28-hexazapentacyclo[24.2.1.02,7.09,14.022,27]nonacosa-1(28),9(14),10,12,22,24,26(29)-heptaene-8,17-dione
Show/Hide
|
C26H30FN7O3
|
2
|
| 1 |
EC50 = 0.33 nM
|
|
|
| 2 |
EC50 = 3.1 nM
|
|
|
|
CP0465614
|
24-(azetidin-1-yl)-11-chloro-21-methyl-15-oxa-7,18,21,25,27,28-hexazapentacyclo[24.2.1.02,7.09,14.022,27]nonacosa-1(28),9(14),10,12,22,24,26(29)-heptaene-8,17-dione
Show/Hide
|
C26H30ClN7O3
|
1
|
| 1 |
EC50 = 0.47 nM
|
|
|
|
CP0465615
|
24-(azetidin-1-yl)-11,21-dimethyl-15-oxa-7,18,21,25,27,28-hexazapentacyclo[24.2.1.02,7.09,14.022,27]nonacosa-1(28),9(14),10,12,22,24,26(29)-heptaene-8,17-dione
Show/Hide
|
C27H33N7O3
|
1
|
| 1 |
EC50 = 0.64 nM
|
|
|
|
CP0531321
|
CHEMBL4746199
Show/Hide
|
C27H31FN6O4
|
1
|
| 1 |
EC50 = 0.74 nM
|
|
|
|
CP0551414
|
(2S)-24-(3-hydroxycyclobutyl)-11,21-dimethyl-15-oxa-7,18,21,25,27,28-hexazapentacyclo[24.2.1.02,7.09,14.022,27]nonacosa-1(28),9(14),10,12,22,24,26(29)-heptaene-8,17-dione
Show/Hide
|
C28H34N6O4
|
1
|
| 1 |
EC50 = 0.77 nM
|
|
|
|
CP0465612
|
(2S)-11-fluoro-24-(3-hydroxyazetidin-1-yl)-21-methyl-15-oxa-7,18,21,25,27,28-hexazapentacyclo[24.2.1.02,7.09,14.022,27]nonacosa-1(28),9(14),10,12,22,24,26(29)-heptaene-8,17-dione
Show/Hide
|
C26H30FN7O4
|
1
|
| 1 |
EC50 = 0.81 nM
|
|
|
|
CP0531318
|
(2S)-24-(3-aminocyclobutyl)-11-fluoro-21-methyl-15-oxa-7,18,21,25,27,28-hexazapentacyclo[24.2.1.02,7.09,14.022,27]nonacosa-1(28),9(14),10,12,22,24,26(29)-heptaene-8,17-dione
Show/Hide
|
C27H32FN7O3
|
1
|
| 1 |
EC50 = 0.87 nM
|
|
|
|
CP0556840
|
(2S)-24-(3-aminocyclobutyl)-11-fluoro-21-methyl-15-oxa-7,18,21,25,27,28-hexazapentacyclo[24.2.1.02,7.09,14.022,27]nonacosa-1(28),9(14),10,12,22,24,26(29)-heptaene-8,17-dione
Show/Hide
|
C27H32FN7O3
|
1
|
| 1 |
EC50 = 1.1 nM
|
|
|
|
CP0573131
|
CHEMBL4752524
Show/Hide
|
C27H31FN6O4
|
1
|
| 1 |
EC50 = 1.1 nM
|
|
|
|
CP0538282
|
(2S)-24-(azetidin-1-yl)-11-fluoro-21-methyl-15-oxa-7,18,21,25,27,28-hexazapentacyclo[24.2.1.02,7.09,14.022,27]nonacosa-1(28),9(14),10,12,22,24,26(29)-heptaen-8-one
Show/Hide
|
C26H32FN7O2
|
1
|
| 1 |
EC50 = 1.4 nM
|
|
|
|
CP0562792
|
(2S)-24-(azetidin-1-yl)-11-fluoro-18,21-dimethyl-15-oxa-7,18,21,25,27,28-hexazapentacyclo[24.2.1.02,7.09,14.022,27]nonacosa-1(28),9(14),10,12,22,24,26(29)-heptaene-8,17-dione
Show/Hide
|
C27H32FN7O3
|
1
|
| 1 |
EC50 = 1.4 nM
|
|
|
|
CP0490664
|
(2S)-24-(azetidin-3-yl)-11-fluoro-21-methyl-15-oxa-7,18,21,25,27,28-hexazapentacyclo[24.2.1.02,7.09,14.022,27]nonacosa-1(28),9(14),10,12,22,24,26(29)-heptaene-8,17-dione
Show/Hide
|
C26H30FN7O3
|
1
|
| 1 |
EC50 = 1.7 nM
|
|
|
|
CP0557671
|
(2S)-23-[(3S)-3-aminopyrrolidin-1-yl]-11,20-dimethyl-15-oxa-7,20,24,26,27-pentazapentacyclo[23.2.1.02,7.09,14.021,26]octacosa-1(27),9(14),10,12,21,23,25(28)-heptaen-8-one
Show/Hide
|
C28H37N7O2
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0573130
|
(2S)-24-[(3S)-3-aminopyrrolidin-1-yl]-11-fluoro-21-methyl-15-oxa-7,18,21,25,27,28-hexazapentacyclo[24.2.1.02,7.09,14.022,27]nonacosa-1(28),9(14),10,12,22,24,26(29)-heptaene-8,17-dione
Show/Hide
|
C27H33FN8O3
|
1
|
| 1 |
EC50 = 2.1 nM
|
|
|
|
CP0571393
|
(2S)-24-(azetidin-1-yl)-11-fluoro-21-methyl-15-oxa-7,18,21,25,27,28-hexazapentacyclo[24.2.1.02,7.09,14.022,27]nonacosa-1(28),9(14),10,12,22,24,26(29)-heptaene-8,19-dione
Show/Hide
|
C26H30FN7O3
|
1
|
| 1 |
EC50 = 2.5 nM
|
|
|
|
CP0558645
|
(2S)-24-(3-aminoazetidin-1-yl)-11-fluoro-21-methyl-15-oxa-7,18,21,25,27,28-hexazapentacyclo[24.2.1.02,7.09,14.022,27]nonacosa-1(28),9(14),10,12,22,24,26(29)-heptaene-8,17-dione
Show/Hide
|
C26H31FN8O3
|
1
|
| 1 |
EC50 = 2.7 nM
|
|
|
|
CP0552722
|
(2S)-24-(azetidin-1-yl)-11-fluoro-21-methyl-18,18-dioxo-15-oxa-18lambda6-thia-7,21,25,27,28-pentazapentacyclo[24.2.1.02,7.09,14.022,27]nonacosa-1(28),9(14),10,12,22,24,26(29)-heptaen-8-one
Show/Hide
|
C26H31FN6O4S
|
1
|
| 1 |
EC50 = 4.6 nM
|
|
|
|
CP0553753
|
(2S)-11-fluoro-21-methyl-24-[3-(methylamino)azetidin-1-yl]-15-oxa-7,18,21,25,27,28-hexazapentacyclo[24.2.1.02,7.09,14.022,27]nonacosa-1(28),9(14),10,12,22,24,26(29)-heptaene-8,17-dione
Show/Hide
|
C27H33FN8O3
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0564092
|
(2S)-24-(azetidin-1-yl)-11-fluoro-21-methyl-15,18-dioxa-7,21,25,27,28-pentazapentacyclo[24.2.1.02,7.09,14.022,27]nonacosa-1(28),9(14),10,12,22,24,26(29)-heptaen-8-one
Show/Hide
|
C26H31FN6O3
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0573129
|
(2S)-23-(azetidin-1-yl)-11-fluoro-20-methyl-15-oxa-7,20,24,26,27-pentazapentacyclo[23.2.1.02,7.09,14.021,26]octacosa-1(27),9(14),10,12,21,23,25(28)-heptaen-8-one
Show/Hide
|
C26H31FN6O2
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0465613
|
(2S)-24-(azetidin-1-yl)-11-fluoro-21-methyl-17-(trifluoromethyl)-15-oxa-7,18,21,25,27,28-hexazapentacyclo[24.2.1.02,7.09,14.022,27]nonacosa-1(28),9(14),10,12,22,24,26(29)-heptaen-8-one
Show/Hide
|
C27H31F4N7O2
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
|
CP0531320
|
(2S)-24-(azetidin-1-yl)-11-fluoro-21-methyl-17,17-dioxo-15-oxa-17lambda6-thia-7,18,21,25,27,28-hexazapentacyclo[24.2.1.02,7.09,14.022,27]nonacosa-1(28),9(14),10,12,22,24,26(29)-heptaen-8-one
Show/Hide
|
C25H30FN7O4S
|
1
|
| 1 |
EC50 = 54 nM
|
|
|
