| Compound ID |
Compound Name |
Compound Formula |
|
CP0260706
|
2,2,2-trifluoroethyl 5-fluoro-2-[(pyrazolo[1,5-a]pyrimidine-3-carbonylamino)methyl]-1-benzofuran-7-carboxylate
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|
C19H12F4N4O4
|
1
|
| 1 |
EC50 = 1900 nM
|
|
|
|
CP0353766
|
N-[(5-chloro-7,9-dioxofuro[2,3-f][1,3]benzoxazin-2-yl)methyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
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|
C18H10ClN5O5
|
1
|
| 1 |
EC50 = 2100 nM
|
|
|
|
CP0248635
|
1-[(E)-4-[5-carbamoyl-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-(3-morpholin-4-ylpropoxy)benzimidazol-1-yl]but-2-enyl]-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-methoxybenzimidazole-5-carboxamide
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|
C42H51N13O7
|
2
|
| 1 |
EC50 = 3000 nM
|
|
|
| 2 |
EC50 > 100000 nM
|
|
|
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CP0344145
|
[(2R)-1,1,1-trifluoropropan-2-yl] 5-chloro-2-[(pyrazolo[1,5-a]pyrimidine-3-carbonylamino)methyl]-1-benzofuran-7-carboxylate
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|
C20H14ClF3N4O4
|
1
|
| 1 |
EC50 = 4600 nM
|
|
|
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CP0176928
|
9-[(1S,6R,8R,9R,10S,15R,17R,18R)-17-(6-aminopurin-9-yl)-3,9,12,18-tetrahydroxy-3,12-dioxo-2,4,7,11,13,16-hexaoxa-3lambda5,12lambda5-diphosphatricyclo[13.3.0.06,10]octadecan-8-yl]-1H-purin-6-one
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|
C20H23N9O13P2
|
1
|
| 1 |
EC50 = 7500 nM
|
|
|
|
CP0353763
|
5-chloro-6-hydroxy-2-[(pyrazolo[1,5-a]pyrimidine-3-carbonylamino)methyl]-1-benzofuran-7-carboxylic acid
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|
C17H11ClN4O5
|
1
|
| 1 |
EC50 = 19000 nM
|
|
|
|
CP0272841
|
3-[(E)-4-[5-carbamoyl-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-(3-morpholin-4-ylpropoxy)benzimidazol-1-yl]but-2-enyl]-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]thieno[2,3-d]imidazole-5-carboxamide
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|
C39H47N13O6S
|
1
|
| 1 |
EC50 = 32820 nM
|
|
|
|
CP0228629
|
2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-1-[(E)-4-[2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-methoxy-5-(1H-1,2,4-triazol-5-yl)benzimidazol-1-yl]but-2-enyl]-7-(3-morpholin-4-ylpropoxy)benzimidazole-5-carboxamide
Show/Hide
|
C43H51N15O6
|
1
|
| 1 |
EC50 = 39510 nM
|
|
|
|
CP0345476
|
3-chloro-5-methyl-2-[(pyrazolo[1,5-a]pyrimidine-3-carbonylamino)methyl]-1-benzofuran-7-carboxylic acid
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|
C18H13ClN4O4
|
1
|
| 1 |
EC50 = 44000 nM
|
|
|
|
CP0261999
|
methyl 2-[(pyrazolo[1,5-a]pyrimidine-3-carbonylamino)methyl]-1-benzofuran-7-carboxylate
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|
C18H14N4O4
|
1
|
| 1 |
EC50 = 45000 nM
|
|
|
|
CP0197694
|
AS-1404
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|
C17H14O4
|
1
|
| 1 |
EC50 = 48000 nM
|
|
|
|
CP0419239
|
1-[(E)-4-[5-(4,5-dihydro-1,3-oxazol-2-yl)-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-methoxybenzimidazol-1-yl]but-2-enyl]-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-(3-morpholin-4-ylpropoxy)benzimidazole-5-carboxamide
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|
C44H53N13O7
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
|
CP0419240
|
N-[5-cyano-1-[(E)-4-[2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-methoxy-5-(1H-1,2,4-triazol-5-yl)benzimidazol-1-yl]but-2-enyl]-7-(3-morpholin-4-ylpropoxy)benzimidazol-2-yl]-2-ethyl-5-methylpyrazole-3-carboxamide
Show/Hide
|
C43H49N15O5
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
|
CP0470936
|
2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-1-[(E)-4-[2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-5-(1H-imidazol-2-yl)-7-(3-morpholin-4-ylpropoxy)benzimidazol-1-yl]but-2-enyl]-7-methoxybenzimidazole-5-carboxamide
Show/Hide
|
C44H52N14O6
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
|
CP0470945
|
1-[(E)-4-[5-cyano-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-(3-morpholin-4-ylpropoxy)benzimidazol-1-yl]but-2-enyl]-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-methoxybenzimidazole-5-carboxamide
Show/Hide
|
C42H49N13O6
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
|
CP0470946
|
2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-1-[(E)-4-[2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-(3-morpholin-4-ylpropoxy)-5-(1H-1,2,4-triazol-5-yl)benzimidazol-1-yl]but-2-enyl]-7-methoxybenzimidazole-5-carboxamide
Show/Hide
|
C43H51N15O6
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
|
CP0533490
|
2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-1-[(E)-4-[2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-5-(1H-imidazol-2-yl)-7-methoxybenzimidazol-1-yl]but-2-enyl]-7-(3-morpholin-4-ylpropoxy)benzimidazole-5-carboxamide
Show/Hide
|
C44H52N14O6
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
|
CP0533491
|
methyl 4-[5-carbamoyl-1-[(E)-4-[5-carbamoyl-2-(4-methoxy-4-oxobutanoyl)-7-(3-morpholin-4-ylpropoxy)benzimidazol-1-yl]but-2-enyl]-7-methoxybenzimidazol-2-yl]-4-oxobutanoate
Show/Hide
|
C38H45N7O11
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
|
CP0534058
|
N-[5-cyano-1-[(E)-4-[5-cyano-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-(3-morpholin-4-ylpropoxy)benzimidazol-1-yl]but-2-enyl]-7-methoxybenzimidazol-2-yl]-2-ethyl-5-methylpyrazole-3-carboxamide
Show/Hide
|
C42H47N13O5
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
|
CP0548400
|
2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-1-[(E)-4-[2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-methoxy-5-(5-methyl-1H-1,2,4-triazol-3-yl)benzimidazol-1-yl]but-2-enyl]-7-(3-morpholin-4-ylpropoxy)benzimidazole-5-carboxamide
Show/Hide
|
C44H53N15O6
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
|
CP0549128
|
2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-1-[(E)-4-[2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-methoxy-5-(1H-1,2,4-triazol-5-yl)benzimidazol-1-yl]but-2-enyl]-7-(3-hydroxypropoxy)benzimidazole-5-carboxamide
Show/Hide
|
C39H44N14O6
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
|
CP0953743
|
(E)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carbonylimino)-1-((1r,4r)-4-((E)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carbonylimino)-7-methoxy-5-(1H-1,2,4-triazol-5-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)cyclohexyl)-7-(3-morpholinopropoxy)-2,3-dihydro-1H-benzo[d]imidazole-5-carboxamide
Show/Hide
|
C45H55N15O6
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
|
CP0273542
|
5-chloro-2-[(pyrazolo[1,5-a]pyrimidine-3-carbonylamino)methyl]-1-benzofuran-7-carboxylic acid
Show/Hide
|
C17H11ClN4O4
|
1
|
| 1 |
EC50 = 55000 nM
|
|
|
|
CP0543190
|
3-[(E)-4-[5-carbamoyl-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-propan-2-yloxybenzimidazol-1-yl]but-2-enyl]-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]thieno[2,3-d]imidazole-5-carboxamide
Show/Hide
|
C35H40N12O5S
|
1
|
| 1 |
EC50 = 63690 nM
|
|
|
|
CP0260705
|
5-chloro-2-[(1,6-naphthyridine-8-carbonylamino)methyl]-1-benzofuran-7-carboxylic acid
Show/Hide
|
C19H12ClN3O4
|
1
|
| 1 |
EC50 = 75000 nM
|
|
|
|
CP0344146
|
4-(4-fluoro-5,6-dimethoxybenzo[b]thiophen- 2-yl)-4-oxobutanoic acid
Show/Hide
|
C14H13FO5S
|
1
|
| 1 |
EC50 = 78000 nM
|
|
|
|
CP0262000
|
2-[(pyrazolo[1,5-a]pyrimidine-3-carbonylamino)methyl]-1-benzofuran-7-carboxylic acid
Show/Hide
|
C17H12N4O4
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0355729
|
dimethyl 5-(pyrazolo[1,5-a]pyrimidine-3-carbonylamino)benzene-1,3-dicarboxylate
Show/Hide
|
C17H14N4O5
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0357335
|
N-[[5-chloro-7-(2H-tetrazol-5-yl)-1-benzofuran-2-yl]methyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
Show/Hide
|
C17H11ClN8O2
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
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CP0357336
|
methyl 2-[(3-oxo-1H-pyrrolo[3,4-c]pyridin-2-yl)methyl]-1-benzofuran-7-carboxylate
Show/Hide
|
C18H14N2O4
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0488208
|
3-[(E)-4-[5-carbamoyl-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-[(3S)-oxolan-3-yl]oxybenzimidazol-1-yl]but-2-enyl]-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]thieno[2,3-d]imidazole-5-carboxamide
Show/Hide
|
C36H40N12O6S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
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CP0488209
|
3-[(E)-4-[5-carbamoyl-7-(cyclopropylmethoxy)-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]benzimidazol-1-yl]but-2-enyl]-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]thieno[2,3-d]imidazole-5-carboxamide
Show/Hide
|
C36H40N12O5S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
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CP0543207
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3-[(E)-4-[5-carbamoyl-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-(oxetan-3-yloxy)benzimidazol-1-yl]but-2-enyl]-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]thieno[2,3-d]imidazole-5-carboxamide
Show/Hide
|
C35H38N12O6S
|
1
|
| 1 |
EC50 > 100000 nM
|
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