Brief Information of the Compound and Protein
Compound Name
N-[(5-chloro-7,9-dioxofuro[2,3-f][1,3]benzoxazin-2-yl)methyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
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PubChem ID
CID: 164866815
Canonical SMILES
Clc1cc2cc(CNC(=O)c3cnn4cccnc34)oc2c2c1oc(=O)[nH]c2=O
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Compound Formula C18H10ClN5O5
Compound Structure
Protein Name
Stimulator of interferon genes protein
Protein Classification
Unclassified protein
Uniprot ID
Q3TBT3
Gene Name
STING1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000584 RAW-Lucia ISG Mus musculus (Mouse)  1
1
EC50 = 2100 nM
   TI
   LI
   LO
   TS
CL000586 RAW-Lucia ISG-KO-STING Mus musculus (Mouse)  1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 940 nM
2 IC50 = 50 nM