Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[(E)-4-[5-carbamoyl-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-(3-morpholin-4-ylpropoxy)benzimidazol-1-yl]but-2-enyl]-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-methoxybenzimidazole-5-carboxamide
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 PubChem ID
CID: 131986624
Canonical SMILES
CCn1nc(C)cc1C(=O)\N=c1/[nH]c2cc(cc(OC)c2n1C\C=C\Cn1c2c(OCCCN3CCOCC3)cc(cc2[nH]\c1=N/C(=O)c1cc(C)nn1CC)C(N)=O)C(N)=O
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Compound Formula C42H51N13O7
Compound Structure
Protein Name
 Protein Info 
Stimulator of interferon genes protein
Protein Classification
Unclassified protein
Uniprot ID
Q3TBT3
Gene Name
STING1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000584 RAW-Lucia ISG
 Cell Line Info 
Mus musculus (Mouse)  2
1
EC50 = 3000 nM
   TI
   LI
   LO
   TS
2
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CL000586 RAW-Lucia ISG-KO-STING
 Cell Line Info 
Mus musculus (Mouse)  1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 54 nM
2 EC50 = 186 nM
3 IC50 = 2.6 nM