| Compound ID |
Compound Name |
Compound Formula |
|
CP0215421
|
(5R)-3-[1-(1H-indol-2-ylmethyl)piperidin-4-yl]-5-(6-methoxyquinolin-4-yl)-1,3-oxazolidin-2-one
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|
C27H28N4O3
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0922180
|
3-(1-((1H-indol-2-yl)methyl)piperidin-4-yl)-5-(6-methoxyquinolin-4-yl)oxazolidin-2-one
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|
C27H28N4O3
|
1
|
| 1 |
IC50 = 25.12 nM
|
|
|
|
CP0495739
|
3-[1-(1H-indol-2-ylmethyl)piperidin-4-yl]-5-(6-methoxy-1,5-naphthyridin-4-yl)-1,3-oxazolidin-2-one
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|
C26H27N5O3
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
|
CP0112269
|
3-[1-[(3,4-dimethylphenyl)methyl]piperidin-4-yl]-5-(6-methoxyquinolin-4-yl)-1,3-oxazolidin-2-one
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|
C27H31N3O3
|
1
|
| 1 |
IC50 = 39.81 nM
|
|
|
|
CP0510945
|
3-[1-[(4-bromophenyl)methyl]piperidin-4-yl]-5-(6-methoxyquinolin-4-yl)-1,3-oxazolidin-2-one
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|
C25H26BrN3O3
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0510944
|
3-[1-[(3,4-dichlorophenyl)methyl]piperidin-4-yl]-5-(6-methoxyquinolin-4-yl)-1,3-oxazolidin-2-one
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|
C25H25Cl2N3O3
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0551871
|
5-(6-methoxyquinolin-4-yl)-3-[1-(3-phenylpropyl)piperidin-4-yl]-1,3-oxazolidin-2-one
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|
C27H31N3O3
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0428072
|
3-(1-hexylpiperidin-4-yl)-5-(6-methoxyquinolin-4-yl)-1,3-oxazolidin-2-one
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|
C24H33N3O3
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0449767
|
3-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-5-(6-methoxyquinolin-4-yl)-1,3-oxazolidin-2-one
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|
C25H26ClN3O3
|
1
|
| 1 |
IC50 = 630.96 nM
|
|
|
|
CP0409484
|
3-[1-(1-benzothiophen-2-ylmethyl)piperidin-4-yl]-5-(6-methoxyquinolin-4-yl)-1,3-oxazolidin-2-one
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|
C27H27N3O3S
|
1
|
| 1 |
IC50 = 794.33 nM
|
|
|
|
CP0464301
|
3-[1-(1H-indol-2-ylmethyl)piperidin-4-yl]-5-quinolin-4-yl-1,3-oxazolidin-2-one
Show/Hide
|
C26H26N4O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0434488
|
3-[1-[(4-methoxyphenyl)methyl]piperidin-4-yl]-5-(6-methoxyquinolin-4-yl)-1,3-oxazolidin-2-one
Show/Hide
|
C26H29N3O4
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0510947
|
5-(6-methoxyquinolin-4-yl)-3-[1-(naphthalen-2-ylmethyl)piperidin-4-yl]-1,3-oxazolidin-2-one
Show/Hide
|
C29H29N3O3
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0551872
|
3-[1-(1-benzofuran-2-ylmethyl)piperidin-4-yl]-5-(6-methoxyquinolin-4-yl)-1,3-oxazolidin-2-one
Show/Hide
|
C27H27N3O4
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0551870
|
3-[3-(1H-indol-2-ylmethylamino)propyl]-5-(6-methoxyquinolin-4-yl)-1,3-oxazolidin-2-one
Show/Hide
|
C25H26N4O3
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0464300
|
5-(6-methoxyquinolin-4-yl)-3-[1-[(1-methylindol-2-yl)methyl]piperidin-4-yl]-1,3-oxazolidin-2-one
Show/Hide
|
C28H30N4O3
|
1
|
| 1 |
IC50 = 3162.28 nM
|
|
|
|
CP0526481
|
5-(6-methoxyquinolin-4-yl)-3-[1-(quinolin-2-ylmethyl)piperidin-4-yl]-1,3-oxazolidin-2-one
Show/Hide
|
C28H28N4O3
|
1
|
| 1 |
IC50 = 3162.28 nM
|
|
|
|
CP0526480
|
3-[1-(3,4-dichlorobenzoyl)piperidin-4-yl]-5-(6-methoxyquinolin-4-yl)-1,3-oxazolidin-2-one
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|
C25H23Cl2N3O4
|
1
|
| 1 |
IC50 = 6309.57 nM
|
|
|
|
CP0542191
|
3-[1-[(3-chlorophenyl)methyl]piperidin-4-yl]-5-(6-methoxyquinolin-4-yl)-1,3-oxazolidin-2-one
Show/Hide
|
C25H26ClN3O3
|
1
|
| 1 |
IC50 = 6309.57 nM
|
|
|
|
CP0551873
|
3-[3-[1H-indol-2-ylmethyl(methyl)amino]propyl]-5-(6-methoxyquinolin-4-yl)-1,3-oxazolidin-2-one
Show/Hide
|
C26H28N4O3
|
1
|
| 1 |
IC50 = 6309.57 nM
|
|
|
|
CP0510946
|
3-[1-(cyclohexylmethyl)piperidin-4-yl]-5-(6-methoxyquinolin-4-yl)-1,3-oxazolidin-2-one
Show/Hide
|
C25H33N3O3
|
1
|
| 1 |
IC50 = 7943.28 nM
|
|
|
|
CP0408027
|
4-[[4-[5-(6-methoxyquinolin-4-yl)-2-oxo-1,3-oxazolidin-3-yl]piperidin-1-yl]methyl]benzonitrile
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|
C26H26N4O3
|
1
|
| 1 |
IC50 = 12589.25 nM
|
|
|
|
CP0495738
|
3-(1-benzylpiperidin-4-yl)-5-(6-methoxyquinolin-4-yl)-1,3-oxazolidin-2-one
Show/Hide
|
C25H27N3O3
|
1
|
| 1 |
IC50 = 12589.25 nM
|
|
|
|
CP0876820
|
3-(1-((1H-indol-3-yl)methyl)piperidin-4-yl)-5-(6-methoxyquinolin-4-yl)oxazolidin-2-one
Show/Hide
|
C27H28N4O3
|
1
|
| 1 |
IC50 < 50118.72 nM
|
|
|
|
CP0897623
|
3-(1-((1H-indol-2-yl)methyl)piperidin-4-yl)-5-(naphthalen-1-yl)oxazolidin-2-one
Show/Hide
|
C27H27N3O2
|
1
|
| 1 |
IC50 < 50118.72 nM
|
|
|
|
CP0897625
|
3-((1-((1H-indol-2-yl)methyl)piperidin-4-yl)methyl)-5-(6-methoxyquinolin-4-yl)oxazolidin-2-one
Show/Hide
|
C28H30N4O3
|
1
|
| 1 |
IC50 < 50118.72 nM
|
|
|
|
CP0897811
|
3-(1-((1H-indol-2-yl)methyl)piperidin-4-yl)-5-(quinolin-3-yl)oxazolidin-2-one
Show/Hide
|
C26H26N4O2
|
1
|
| 1 |
IC50 < 50118.72 nM
|
|
|
|
CP0915883
|
3-(1-(3,4-dichlorophenylsulfonyl)piperidin-4-yl)-5-(6-methoxyquinolin-4-yl)oxazolidin-2-one
Show/Hide
|
C24H23Cl2N3O5S
|
1
|
| 1 |
IC50 < 50118.72 nM
|
|
|
|
CP0922178
|
3-(1-((1H-indol-2-yl)methyl)piperidin-4-yl)-5-(quinolin-2-yl)oxazolidin-2-one
Show/Hide
|
C26H26N4O2
|
1
|
| 1 |
IC50 < 50118.72 nM
|
|
|
|
CP0922179
|
3-(1-((1H-indol-2-yl)methyl)pyrrolidin-3-yl)-5-(6-methoxyquinolin-4-yl)oxazolidin-2-one
Show/Hide
|
C26H26N4O3
|
1
|
| 1 |
IC50 < 50118.72 nM
|
|
|
|
CP0933849
|
3-(1-((1H-indol-2-yl)methyl)azepan-3-yl)-5-(6-methoxyquinolin-4-yl)oxazolidin-2-one
Show/Hide
|
C28H30N4O3
|
1
|
| 1 |
IC50 < 50118.72 nM
|
|
|
|
CP0939746
|
3-(1-biphenyl-4-ylmethyl-piperidin-4-yl)-5-(6-methoxy-quinolin-4-yl)-oxazolidin-2-one
Show/Hide
|
C31H31N3O3
|
1
|
| 1 |
IC50 < 50118.72 nM
|
|
|
|
CP0939791
|
3-(1-(2-chlorobenzyl)piperidin-4-yl)-5-(6-methoxyquinolin-4-yl)oxazolidin-2-one
Show/Hide
|
C25H26ClN3O3
|
1
|
| 1 |
IC50 < 50118.72 nM
|
|
|
|
CP0955403
|
5-(6-methoxyquinolin-4-yl)-3-(1-methylpiperidin-4-yl)oxazolidin-2-one
Show/Hide
|
C19H23N3O3
|
1
|
| 1 |
IC50 < 50118.72 nM
|
|
|
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CP0955404
|
3-(1-((1H-indol-2-yl)methyl)piperidin-4-yl)-5-(pyridin-4-yl)oxazolidin-2-one
Show/Hide
|
C22H24N4O2
|
1
|
| 1 |
IC50 < 50118.72 nM
|
|
|
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CP0955405
|
3-((1-((1H-indol-2-yl)methyl)piperidin-3-yl)methyl)-5-(6-methoxyquinolin-4-yl)oxazolidin-2-one
Show/Hide
|
C28H30N4O3
|
1
|
| 1 |
IC50 < 50118.72 nM
|
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