Brief Information of the Compound and Protein
Compound Name
(5R)-3-[1-(1H-indol-2-ylmethyl)piperidin-4-yl]-5-(6-methoxyquinolin-4-yl)-1,3-oxazolidin-2-one
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PubChem ID
CID: 16112836
SID: 24759794
Canonical SMILES
COc1ccc2nccc([C@@H]3CN(C4CCN(Cc5cc6ccccc6[nH]5)CC4)C(=O)O3)c2c1
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Compound Formula C27H28N4O3
Compound Structure
Protein Name
C-C chemokine receptor type 8
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P51685
Gene Name
CCR8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000059 HuT 78 Homo sapiens (Human)  1
1
IC50 = 501.19 nM
   TI
   LI
   LO
   TS
CL000194 RBL-1 Rattus norvegicus (Rat)  1
1
IC50 = 19.95 nM
   TI
   LI
   LO
   TS
CL000783 UE6E7T-2 Homo sapiens (Human)  1
1
IC50 = 100 nM
   TI
   LI
   LO
   TS