Brief Information of the Cell Line and Protein
Cell Line ID: CL000286 , HCC1806
 Cell Line Info 
Synonyms
Hcc1806
HCC-1806
Hamon Cancer Center 1806
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1258
Protein ID: PT03003 , Histone-lysine N-methyltransferase EZH2
 Protein Info 
Gene Name EZH2
Organism Homo sapiens, Human
Protein Classification Epigenetic regulator
Uniprot ID Q15910
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000286
 Cell Line Info 
 Protein ID: PT03003
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0025037
 Compound Info 
N-[(6-methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-6-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]-1-propan-2-ylindazole-4-carboxamide
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C31H39N7O2
  1
1
IC50 = 79 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0025055
 Compound Info 
N-[(6-methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-6-[2-(4-methylpiperazin-1-yl)pyridin-4-yl]-1-propan-2-ylindazole-4-carboxamide
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C31H39N7O2
  1
1
IC50 = 174 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0016806
 Compound Info 
N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-6-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]-1-propan-2-ylindazole-4-carboxamide
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C29H35N7O2
  1
1
IC50 = 324 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0024696
 Compound Info 
N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-6-[2-(4-methylpiperazin-1-yl)pyridin-4-yl]-1-propan-2-ylindazole-4-carboxamide
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C29H35N7O2
  1
1
IC50 = 1995 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0021090
 Compound Info 
6-cyclopropyl-N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-1-propan-2-ylindazole-4-carboxamide
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C22H26N4O2
  1
1
IC50 = 2510 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0028621
 Compound Info 
6-cyclopropyl-N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-1-propan-2-ylpyrazolo[3,4-b]pyridine-4-carboxamide
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C21H25N5O2
  1
1
IC50 = 10632 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS