| Compound ID |
Compound Name |
Compound Formula |
|
CP0551567
|
3-[2-(4-fluoro-2-methylphenyl)-1H-indol-5-yl]propanoic acid
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|
C18H16FNO2
|
3
|
| 1 |
EC50 = 0.04 nM
|
|
|
| 2 |
EC50 = 521 nM
|
|
|
| 3 |
EC50 = 681 nM
|
|
|
|
CP0514814
|
3-[2-(4-chloro-2-methylphenyl)-1H-indol-5-yl]propanoic acid
Show/Hide
|
C18H16ClNO2
|
1
|
| 1 |
EC50 = 0.25 nM
|
|
|
|
CP0547966
|
3-[2-(3-chloro-2-methylphenyl)-1H-indol-5-yl]propanoic acid
Show/Hide
|
C18H16ClNO2
|
1
|
| 1 |
EC50 = 0.38 nM
|
|
|
|
CP0514817
|
3-[2-(2,4-dimethylphenyl)-1H-indol-5-yl]propanoic acid
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|
C19H19NO2
|
1
|
| 1 |
EC50 = 0.41 nM
|
|
|
|
CP0479614
|
3-[2-(2,5-dimethylphenyl)-1H-indol-5-yl]propanoic acid
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|
C19H19NO2
|
3
|
| 1 |
EC50 = 0.417 nM
|
|
|
| 2 |
EC50 = 7530 nM
|
|
|
| 3 |
EC50 = 12880 nM
|
|
|
|
CP0551568
|
3-[2-(2,6-dimethylphenyl)-1H-indol-5-yl]propanoic acid
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|
C19H19NO2
|
1
|
| 1 |
EC50 = 0.729 nM
|
|
|
|
CP0514813
|
3-[2-(4-bromo-2-methylphenyl)-1H-indol-5-yl]propanoic acid
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|
C18H16BrNO2
|
1
|
| 1 |
EC50 = 0.73 nM
|
|
|
|
CP0563659
|
(2S,3S)-3-cyclopropyl-3-[(2R)-2-[1-[(1S)-1-[5-fluoro-2-(trifluoromethoxy)phenyl]ethyl]piperidin-4-yl]-3,4-dihydro-2H-chromen-7-yl]-2-methylpropanoic acid
Show/Hide
|
C30H35F4NO4
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0551564
|
3-[2-(2,6-dichlorophenyl)-1H-indol-5-yl]propanoic acid
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|
C17H13Cl2NO2
|
1
|
| 1 |
EC50 = 2.41 nM
|
|
|
|
CP0417959
|
3-[6-[[3-(2,6-dimethylphenyl)phenyl]methoxy]pyridin-3-yl]propanoic acid
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|
C23H23NO3
|
1
|
| 1 |
EC50 = 3.5 nM
|
|
|
|
CP0112522
|
(3S)-3-ethoxy-3-[4-[[(1R)-4-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl]oxy]phenyl]propanoic acid
Show/Hide
|
C21H21F3O4
|
1
|
| 1 |
EC50 = 3.7 nM
|
|
|
|
CP0420293
|
3-[5-[[3-(2,6-dimethylphenyl)phenyl]methoxy]pyrazin-2-yl]propanoic acid
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|
C22H22N2O3
|
1
|
| 1 |
EC50 = 3.8 nM
|
|
|
|
CP0409594
|
(3S)-3-[4-[(3,4-dichlorophenyl)methoxy]phenyl]-3-ethoxypropanoic acid
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|
C18H18Cl2O4
|
1
|
| 1 |
EC50 = 3.9 nM
|
|
|
|
CP0392047
|
(1S,2S)-2-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylamino]phenyl]cyclopropane-1-carboxamide
Show/Hide
|
C22H20F3N3OS
|
1
|
| 1 |
EC50 = 4.467 nM
|
|
|
|
CP0433548
|
3-[4-[[3-[4-(2-ethoxyethoxy)-2,6-dimethylphenyl]phenyl]methoxy]-2-fluorophenyl]propanoic acid
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|
C28H31FO5
|
2
|
| 1 |
EC50 = 4.5 nM
|
|
|
| 2 |
Ki = 12 nM
|
|
|
|
CP0547981
|
3-[2-(2,3-dichlorophenyl)-1H-indol-5-yl]propanoic acid
Show/Hide
|
C17H13Cl2NO2
|
1
|
| 1 |
EC50 = 4.78 nM
|
|
|
|
CP0521208
|
2-[2-fluoro-4-[[3-(2-methylphenyl)phenyl]methylamino]phenoxy]acetic acid
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|
C22H20FNO3
|
1
|
| 1 |
EC50 = 4.8 nM
|
|
|
|
CP0388788
|
(3S)-3-[4-[[(1R)-4-chloro-2,3-dihydro-1H-inden-1-yl]oxy]phenyl]-3-ethoxypropanoic acid
Show/Hide
|
C20H21ClO4
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0188410
|
(3S)-3-ethoxy-3-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]propanoic acid
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|
C19H19F3O4
|
1
|
| 1 |
EC50 = 5.3 nM
|
|
|
|
CP0514811
|
Mk-8666
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|
C29H31NO6S
|
1
|
| 1 |
EC50 = 5.6 nM
|
|
|
|
CP0449573
|
3-{4-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]-2-fluorophenyl}propanoic Acid
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|
C24H23FO3
|
5
|
| 1 |
EC50 = 5.7 nM
|
|
|
| 2 |
EC50 = 7.7 nM
|
|
|
| 3 |
EC50 = 14.2 nM
|
|
|
| 4 |
EC50 = 30 nM
|
|
|
| 5 |
Ki = 32 nM
|
|
|
|
CP0432420
|
3-[4-[(3,4-dichlorophenyl)methoxy]phenyl]-3-ethoxypropanoic acid
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|
C18H18Cl2O4
|
1
|
| 1 |
EC50 = 6.2 nM
|
|
|
|
CP0438080
|
3-(4-{[(2',6'-Dimethylbiphenyl-3-yl)methyl]amino}phenyl)-propanoic Acid
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|
C24H25NO2
|
1
|
| 1 |
EC50 = 6.3 nM
|
|
|
|
CP0378805
|
3-{4-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]phenyl}propanoic Acid
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|
C24H24O3
|
5
|
| 1 |
EC50 = 6.7 nM
|
|
|
| 2 |
EC50 = 8 nM
|
|
|
| 3 |
EC50 = 8.8 nM
|
|
|
| 4 |
EC50 = 22 nM
|
|
|
| 5 |
Ki = 46 nM
|
|
|
|
CP0459742
|
(1S,2S)-N-hydroxy-2-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylamino]phenyl]cyclopropane-1-carboxamide
Show/Hide
|
C22H20F3N3O2S
|
1
|
| 1 |
EC50 = 6.918 nM
|
|
|
|
CP0468122
|
3-ethoxy-3-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]propanoic acid
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|
C19H19F3O4
|
1
|
| 1 |
EC50 = 7.2 nM
|
|
|
|
CP0431840
|
(3S)-3-ethoxy-3-[4-[[3-fluoro-4-(trifluoromethyl)phenyl]methoxy]phenyl]propanoic acid
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|
C19H18F4O4
|
1
|
| 1 |
EC50 = 7.5 nM
|
|
|
|
CP0567120
|
2-[(3S)-6-[[4-chloro-3-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C22H20ClNO5
|
1
|
| 1 |
EC50 = 7.9 nM
|
|
|
|
CP0506588
|
3-[6-[[3-(2,6-dimethylphenyl)phenyl]methoxy]pyridin-3-yl]-2-fluoropropanoic acid
Show/Hide
|
C23H22FNO3
|
1
|
| 1 |
EC50 = 8.6 nM
|
|
|
|
CP0449548
|
(1S,2S)-N-cyclobutyl-2-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylamino]phenyl]cyclopropane-1-carboxamide
Show/Hide
|
C26H26F3N3OS
|
1
|
| 1 |
EC50 = 9.12 nM
|
|
|
|
CP0447098
|
3-[6-[[3-(2,6-dimethylphenyl)phenyl]methoxy]-4-methylpyridin-3-yl]propanoic acid
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|
C24H25NO3
|
1
|
| 1 |
EC50 = 9.3 nM
|
|
|
|
CP0452541
|
3-[4-[[2-chloro-5-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
|
C21H19ClFNO4
|
1
|
| 1 |
EC50 = 9.3 nM
|
|
|
|
CP0459097
|
3-[2-(2-bromophenyl)-1H-indol-5-yl]propanoic acid
Show/Hide
|
C17H14BrNO2
|
1
|
| 1 |
EC50 = 9.4 nM
|
|
|
|
CP0378806
|
3-{4-[(2',4'-Dimethylbiphenyl-3-yl)methoxy]phenyl}propanoic Acid
Show/Hide
|
C24H24O3
|
1
|
| 1 |
EC50 = 9.9 nM
|
|
|
|
CP0409589
|
(3S)-3-ethoxy-3-[4-[[(1R)-4-(trifluoromethoxy)-2,3-dihydro-1H-inden-1-yl]oxy]phenyl]propanoic acid
Show/Hide
|
C21H21F3O5
|
1
|
| 1 |
EC50 = 9.9 nM
|
|
|
|
CP0476021
|
2-[6-[[3-(2,6-dimethylphenyl)-4-phenylmethoxyphenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C32H30O5
|
2
|
| 1 |
EC50 = 10 nM
|
|
|
| 2 |
Ki = 6.9 nM
|
|
|
|
CP0483770
|
3-[6-[[3-(2,6-dimethylphenyl)phenyl]methoxy]pyridin-3-yl]butanoic acid
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|
C24H25NO3
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0425730
|
3-cyclopropyl-3-[3-[[1-[2-(4,4-dimethylpentyl)-5-methoxyphenyl]piperidin-4-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C32H45NO4
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0452540
|
3-[4-[[5-(3,5-dimethyl-1,2-oxazol-4-yl)-2-fluorophenyl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
|
C21H19F2NO4
|
1
|
| 1 |
EC50 = 11.1 nM
|
|
|
|
CP0393697
|
2-[(3R,8S)-3-[3-(trifluoromethyl)phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C19H15F3O5
|
1
|
| 1 |
EC50 = 11.3 nM
|
|
|
|
CP0559743
|
2-[4-[[3-(4-ethoxy-2-methylphenyl)phenyl]methylamino]-2-fluorophenoxy]acetic acid
Show/Hide
|
C24H24FNO4
|
1
|
| 1 |
EC50 = 11.6 nM
|
|
|
|
CP0438395
|
3-[4-[[3-(4-methoxy-2,6-dimethylphenyl)phenyl]methoxy]phenyl]propanoic acid
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|
C25H26O4
|
2
|
| 1 |
EC50 = 12 nM
|
|
|
| 2 |
Ki = 25 nM
|
|
|
|
CP0439940
|
(3S)-3-[4-[[3-(4-chloro-2-methylphenyl)phenyl]methoxy]phenyl]-3-(1-methyltetrazol-5-yl)propanoic acid
Show/Hide
|
C25H23ClN4O3
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0431842
|
3-[4-[(4-chlorophenyl)methoxy]phenyl]-3-ethoxypropanoic acid
Show/Hide
|
C18H19ClO4
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0431847
|
3-[4-[(3,4-dichlorophenyl)methoxy]-2-fluorophenyl]-3-ethoxypropanoic acid
Show/Hide
|
C18H17Cl2FO4
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0484559
|
(3S)-3-ethoxy-3-[4-[[(1R)-4-ethyl-2,3-dihydro-1H-inden-1-yl]oxy]phenyl]propanoic acid
Show/Hide
|
C22H26O4
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0551721
|
(3S)-3-ethoxy-3-[4-[[(1R)-4-propan-2-yl-2,3-dihydro-1H-inden-1-yl]oxy]phenyl]propanoic acid
Show/Hide
|
C23H28O4
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0409971
|
3-[4-[[3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-methylphenyl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
|
C22H22FNO4
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0425727
|
(3S)-3-cyclopropyl-3-[2-[[1-[2-[2,2-dimethylpropyl-(6-methylpyridin-2-yl)carbamoyl]-5-methoxyphenyl]piperidin-4-yl]methoxy]pyridin-4-yl]propanoic acid
Show/Hide
|
C36H46N4O5
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0459740
|
(1S,2S)-2-[4-[(3-phenoxyphenyl)methylamino]phenyl]-N-propan-2-ylcyclopropane-1-carboxamide
Show/Hide
|
C26H28N2O2
|
1
|
| 1 |
EC50 = 12.59 nM
|
|
|
|
CP0494669
|
3-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylamino]phenyl]propanamide
Show/Hide
|
C21H20F3N3OS
|
1
|
| 1 |
EC50 = 12.88 nM
|
|
|
|
CP0458239
|
3-[4-[[3-[4-(2-ethoxyethoxy)-2,6-dimethylphenyl]phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C28H32O5
|
2
|
| 1 |
EC50 = 13 nM
|
|
|
| 2 |
Ki = 23 nM
|
|
|
|
CP0433602
|
2-[(3S)-6-[[3-[4-[(4-hydroxy-1,1-dioxothian-4-yl)methoxy]-2,6-dimethylphenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C31H34O8S
|
2
|
| 1 |
EC50 = 13 nM
|
|
|
| 2 |
Ki = 24 nM
|
|
|
|
CP0136178
|
3-(4-{[(3-phenoxyphenyl)methyl]amino}phenyl)propanoic acid
Show/Hide
|
C22H21NO3
|
4
|
| 1 |
EC50 = 13 nM
|
|
|
| 2 |
EC50 = 47.86 nM
|
|
|
| 3 |
EC50 = 50 nM
|
|
|
| 4 |
EC50 = 64.57 nM
|
|
|
|
CP0443030
|
(3S)-3-[4-[[(1R)-4-cyclopropyl-2,3-dihydro-1H-inden-1-yl]oxy]phenyl]-3-ethoxypropanoic acid
Show/Hide
|
C23H26O4
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0466692
|
3-ethoxy-3-[4-[(4-fluoronaphthalen-1-yl)methoxy]phenyl]propanoic acid
Show/Hide
|
C22H21FO4
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0484575
|
(3S)-3-ethoxy-3-[4-[[(1R)-5-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl]oxy]phenyl]propanoic acid
Show/Hide
|
C21H21F3O4
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0541682
|
(3S)-3-ethoxy-3-[4-[[2-fluoro-4-(trifluoromethyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C19H18F4O4
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0179633
|
AMG-837
Show/Hide
|
C26H21F3O3
|
5
|
| 1 |
EC50 = 13 nM
|
|
|
| 2 |
EC50 = 60 nM
|
|
|
| 3 |
EC50 = 80 nM
|
|
|
| 4 |
EC50 = 104 nM
|
|
|
| 5 |
EC50 = 8800 nM
|
|
|
|
CP0179860
|
2-[(3R,8S)-3-(3-bromophenyl)-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C18H15BrO5
|
1
|
| 1 |
EC50 = 13.5 nM
|
|
|
|
CP0423367
|
3-[4-[[3-(2,6-dimethyl-4-phenylmethoxyphenyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C31H30O4
|
2
|
| 1 |
EC50 = 14 nM
|
|
|
| 2 |
Ki = 15 nM
|
|
|
|
CP0434952
|
2-[(3S)-6-[[3-[4-(2-ethylsulfonylethoxy)-2,6-dimethylphenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C29H32O7S
|
2
|
| 1 |
EC50 = 14 nM
|
|
|
| 2 |
Ki = 37 nM
|
|
|
|
CP0862686
|
[(3S)-6-({2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy]-biphenyl-3-yl}methoxy)-2,3-dihydro-1-benzofuran-3-yl]acetic Acid Hemihydrate
Show/Hide
|
C29H34O8S
|
3
|
| 1 |
EC50 = 14 nM
|
|
|
| 2 |
EC50 = 41.8 nM
|
|
|
| 3 |
Ki = 38 nM
|
|
|
|
CP0447100
|
3-[6-[[3-(2,6-dimethylphenyl)phenyl]methoxy]pyridin-3-yl]-3-ethoxypropanoic acid
Show/Hide
|
C25H27NO4
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0104146
|
2-[(3S)-6-[[3-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C29H32O7S
|
13
|
| 1 |
EC50 = 14 nM
|
|
|
| 2 |
EC50 = 16 nM
|
|
|
| 3 |
EC50 = 27 nM
|
|
|
| 4 |
EC50 = 27.5 nM
|
|
|
| 5 |
EC50 = 29.6 nM
|
|
|
| 6 |
EC50 = 31.8 nM
|
|
|
| 7 |
EC50 = 32.5 nM
|
|
|
| 8 |
EC50 = 33.6 nM
|
|
|
| 9 |
EC50 = 37.1 nM
|
|
|
| 10 |
EC50 = 38.6 nM
|
|
|
| 11 |
EC50 = 45 nM
|
|
|
| 12 |
EC50 > 1000 nM
|
|
|
| 13 |
Kd = 11.9 nM
|
|
|
|
CP0471090
|
2-[(3S)-6-[2-[3-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]ethyl]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C30H34O6S
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0497479
|
(1S,2S)-N-hydroxy-2-[4-[(3-phenoxyphenyl)methylamino]phenyl]cyclopropane-1-carboxamide
Show/Hide
|
C23H22N2O3
|
1
|
| 1 |
EC50 = 14.79 nM
|
|
|
|
CP0486909
|
3-[4-[[3-[4-(cyclopropylmethoxy)-2,6-dimethylphenyl]phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C28H30O4
|
2
|
| 1 |
EC50 = 15 nM
|
|
|
| 2 |
Ki = 16 nM
|
|
|
|
CP0508632
|
3-[2-fluoro-4-[[3-[4-[(4-hydroxy-1,1-dioxothian-4-yl)methoxy]-2,6-dimethylphenyl]phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C30H33FO7S
|
2
|
| 1 |
EC50 = 15 nM
|
|
|
| 2 |
Ki = 19 nM
|
|
|
|
CP0429575
|
3-[4-[[3-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C28H32O6S
|
1
|
| 1 |
EC50 = 15.49 nM
|
|
|
|
CP0578067
|
2-[2-fluoro-4-[[3-[2-(trifluoromethyl)phenyl]phenyl]methylamino]phenoxy]acetic acid
Show/Hide
|
C22H17F4NO3
|
1
|
| 1 |
EC50 = 15.7 nM
|
|
|
|
CP0399434
|
3-[4-[[4-chloro-3-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
|
C21H19ClFNO4
|
1
|
| 1 |
EC50 = 15.9 nM
|
|
|
|
CP0429442
|
2-[(3S)-6-[[3-[3-fluoro-2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C29H31FO7S
|
2
|
| 1 |
EC50 = 16 nM
|
|
|
| 2 |
Ki = 18 nM
|
|
|
|
CP0433891
|
2-[(3S)-6-[[3-[3-chloro-2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C29H31ClO7S
|
2
|
| 1 |
EC50 = 16 nM
|
|
|
| 2 |
Ki = 19 nM
|
|
|
|
CP0439908
|
2-[(3S)-6-[[3-[4-(2-ethoxyethoxy)-2,6-dimethylphenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C29H32O6
|
2
|
| 1 |
EC50 = 16 nM
|
|
|
| 2 |
Ki = 23 nM
|
|
|
|
CP0467046
|
2-[(3R,8S)-3-(3,4-dichlorophenyl)-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C18H14Cl2O5
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0514816
|
3-[2-(5-chloro-2-methylphenyl)-1H-indol-5-yl]propanoic acid
Show/Hide
|
C18H16ClNO2
|
1
|
| 1 |
EC50 = 16.26 nM
|
|
|
|
CP0420967
|
2-[(3S)-6-[[3-[2,6-dimethyl-4-[3-(2-oxopyrrolidin-1-yl)propoxy]phenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C32H35NO6
|
2
|
| 1 |
EC50 = 17 nM
|
|
|
| 2 |
Ki = 31 nM
|
|
|
|
CP0433890
|
2-[(3S)-6-[[3-[2,6-diethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C31H36O7S
|
2
|
| 1 |
EC50 = 17 nM
|
|
|
| 2 |
Ki = 11 nM
|
|
|
|
CP0459310
|
2-[(3S)-6-[[3-[4-(imidazo[1,2-a]pyridin-5-ylmethoxy)-2,6-dimethylphenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C33H30N2O5
|
2
|
| 1 |
EC50 = 17 nM
|
|
|
| 2 |
Ki = 15 nM
|
|
|
|
CP0461990
|
2-[(3S)-6-[[3-[3,5-dichloro-2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C29H30Cl2O7S
|
2
|
| 1 |
EC50 = 17 nM
|
|
|
| 2 |
Ki = 12 nM
|
|
|
|
CP0466394
|
3-cyclopropyl-3-[3-[[1-[2-[2,2-dimethylpropyl-(6-methylpyridin-2-yl)carbamoyl]-5-methoxyphenyl]piperidin-4-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C37H47N3O5
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0466398
|
3-cyclopropyl-3-[2-[[1-[2-[2,2-dimethylpropyl-(6-methylpyridin-2-yl)carbamoyl]-5-methoxyphenyl]piperidin-4-yl]methoxy]pyridin-4-yl]propanoic acid
Show/Hide
|
C36H46N4O5
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0433888
|
2-[(3S)-6-[[3-[2,6-dimethyl-4-[(3-methyloxetan-3-yl)methoxy]phenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C30H32O6
|
2
|
| 1 |
EC50 = 18 nM
|
|
|
| 2 |
Ki = 25 nM
|
|
|
|
CP0434953
|
2-[(3S)-6-[[3-[4-[(2,4-dimethyl-1,3-thiazol-5-yl)methoxy]-2,6-dimethylphenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C31H31NO5S
|
2
|
| 1 |
EC50 = 18 nM
|
|
|
| 2 |
Ki = 12 nM
|
|
|
|
CP0475686
|
2-[(3S)-6-[[3-[2,3,5,6-tetramethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C31H36O7S
|
2
|
| 1 |
EC50 = 18 nM
|
|
|
| 2 |
Ki = 33 nM
|
|
|
|
CP0420292
|
3-[6-[[3-(2,6-dimethylphenyl)phenyl]methoxy]pyridin-3-yl]-3-fluoropropanoic acid
Show/Hide
|
C23H22FNO3
|
1
|
| 1 |
EC50 = 18 nM
|
|
|
|
CP0489838
|
2-[6-[[4-chloro-3-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C22H20ClNO5
|
1
|
| 1 |
EC50 = 18.6 nM
|
|
|
|
CP0438082
|
3-{4-[(2',3'-Dimethylbiphenyl-3-yl)methoxy]phenyl}propanoic Acid
Show/Hide
|
C24H24O3
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
|
CP0441136
|
2-[(3S)-6-[[3-[4-(1,1-dioxothian-4-yl)oxy-3-fluoro-2,6-dimethylphenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C30H31FO7S
|
2
|
| 1 |
EC50 = 19 nM
|
|
|
| 2 |
Ki = 31 nM
|
|
|
|
CP0876507
|
[(3S)-6-({2',6'-Dimethyl-4'-[(1-methylpiperidin-4-yl)oxy]-biphenyl-3-yl}methoxy)-2,3-dihydro-1-benzofuran-3-yl]acetic Acid Hydrochloride
Show/Hide
|
C31H36ClNO5
|
2
|
| 1 |
EC50 = 19 nM
|
|
|
| 2 |
Ki = 8.8 nM
|
|
|
|
CP0444946
|
(3S)-3-ethoxy-3-[4-[[(1S)-4-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl]oxy]phenyl]propanoic acid
Show/Hide
|
C21H21F3O4
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
|
CP0409599
|
3-[4-[(3-chlorophenyl)methoxy]phenyl]-3-ethoxypropanoic acid
Show/Hide
|
C18H19ClO4
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
|
CP0433638
|
2-[(3S,8S)-3-[3-(2-methylphenyl)phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C25H22O5
|
1
|
| 1 |
EC50 = 19.1 nM
|
|
|
|
CP0575061
|
2-[4-[[3-(2-chlorophenyl)phenyl]methylamino]-2-fluorophenoxy]acetic acid
Show/Hide
|
C21H17ClFNO3
|
1
|
| 1 |
EC50 = 19.3 nM
|
|
|
|
CP0404984
|
3-{4-[(2'-Chlorobiphenyl-3-yl)methoxy]phenyl}propanoic Acid
Show/Hide
|
C22H19ClO3
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
|
CP0489801
|
3-[4-[[3-(2,6-dimethylphenyl)-4-methoxyphenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C25H26O4
|
2
|
| 1 |
EC50 = 20 nM
|
|
|
| 2 |
Ki = 47 nM
|
|
|
|
CP0392416
|
3-ethoxy-3-[4-[(2-methylphenyl)methoxy]phenyl]propanoic acid
Show/Hide
|
C19H22O4
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
|
CP0574384
|
(3S)-3-ethoxy-3-[6-[[(1R)-4-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl]oxy]pyridin-3-yl]propanoic acid
Show/Hide
|
C20H20F3NO4
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
|
CP0514812
|
3-[2-(2,4-dichlorophenyl)-1H-indol-5-yl]propanoic acid
Show/Hide
|
C17H13Cl2NO2
|
1
|
| 1 |
EC50 = 20.59 nM
|
|
|
|
CP0476018
|
2-[6-[[3-(2-methylnaphthalen-1-yl)phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C28H24O4
|
2
|
| 1 |
EC50 = 21 nM
|
|
|
| 2 |
Ki = 41 nM
|
|
|
|
CP0442945
|
(3S)-3-ethoxy-3-[4-[[(3S)-7-(trifluoromethyl)-2,3-dihydro-1-benzofuran-3-yl]oxy]phenyl]propanoic acid
Show/Hide
|
C20H19F3O5
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
|
CP0437811
|
2-[(3S)-6-[[3-[4-(1,1-dioxothian-4-yl)oxy-2,6-dimethylphenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C30H32O7S
|
2
|
| 1 |
EC50 = 22 nM
|
|
|
| 2 |
Ki = 36 nM
|
|
|
|
CP0417304
|
2-[6-[[3-(2,6-dimethylphenyl)phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C25H24O4
|
4
|
| 1 |
EC50 = 22 nM
|
|
|
| 2 |
EC50 = 27 nM
|
|
|
| 3 |
EC50 = 38.4 nM
|
|
|
| 4 |
Ki = 170 nM
|
|
|
|
CP0559742
|
2-[4-[[3-(2-chloro-4-methylphenyl)phenyl]methylamino]-2-fluorophenoxy]acetic acid
Show/Hide
|
C22H19ClFNO3
|
1
|
| 1 |
EC50 = 22.5 nM
|
|
|
|
CP0888633
|
3-(4-((3-(3,5-dimethylisoxazol-4-yl)-4-methoxybenzyl)oxy)-2-fluorophenyl)propanoic acid
Show/Hide
|
C22H22FNO5
|
1
|
| 1 |
EC50 = 22.9 nM
|
|
|
|
CP0433549
|
3-[4-[[3-[2,6-dimethyl-4-(oxan-4-yloxy)phenyl]phenyl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
|
C29H31FO5
|
2
|
| 1 |
EC50 = 23 nM
|
|
|
| 2 |
Ki = 20 nM
|
|
|
|
CP0461947
|
3-[4-[[3-[4-(1,1-dioxothian-4-yl)oxy-2,6-dimethylphenyl]phenyl]methylamino]-2-fluorophenyl]propanoic acid
Show/Hide
|
C29H32FNO5S
|
2
|
| 1 |
EC50 = 23 nM
|
|
|
| 2 |
Ki = 18 nM
|
|
|
|
CP0389853
|
2-[6-[[3-(2,6-dimethylphenyl)phenyl]methoxy]-1,2,3,4-tetrahydronaphthalen-1-yl]acetic acid
Show/Hide
|
C27H28O3
|
3
|
| 1 |
EC50 = 23 nM
|
|
|
| 2 |
EC50 = 27 nM
|
|
|
| 3 |
Ki = 59 nM
|
|
|
|
CP0504509
|
3-ethoxy-3-[4-[(3-phenoxyphenyl)methoxy]phenyl]propanoic acid
Show/Hide
|
C24H24O5
|
1
|
| 1 |
EC50 = 23 nM
|
|
|
|
CP0389856
|
2-[6-[[3-(2,6-dimethylphenyl)-4-methoxyphenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C26H26O5
|
2
|
| 1 |
EC50 = 24 nM
|
|
|
| 2 |
Ki = 130 nM
|
|
|
|
CP0439909
|
2-[6-[[3-[2,6-dimethyl-4-[(3-methyloxetan-3-yl)methoxy]phenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C30H32O6
|
2
|
| 1 |
EC50 = 24 nM
|
|
|
| 2 |
Ki = 21 nM
|
|
|
|
CP0477493
|
2-[4-[[3-(4-ethoxy-2,6-dimethylphenyl)phenyl]methylamino]-2-fluorophenoxy]acetic acid
Show/Hide
|
C25H26FNO4
|
1
|
| 1 |
EC50 = 24.2 nM
|
|
|
|
CP0385019
|
3-[4-[[5-(3,5-dimethyl-1,2-oxazol-4-yl)-2-methoxyphenyl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
|
C22H22FNO5
|
1
|
| 1 |
EC50 = 24.3 nM
|
|
|
|
CP0399435
|
3-[4-[[3-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
|
C21H20FNO4
|
1
|
| 1 |
EC50 = 24.8 nM
|
|
|
|
CP0452173
|
3-[4-[[3-[4-(trifluoromethyl)phenyl]phenyl]methoxy]phenyl]hex-4-ynoic acid
Show/Hide
|
C26H21F3O3
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0032783
|
3-[4-[[3-[4-(1,1-dioxothian-4-yl)oxy-2,6-dimethylphenyl]phenyl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
|
C29H31FO6S
|
2
|
| 1 |
EC50 = 25 nM
|
|
|
| 2 |
Ki = 16 nM
|
|
|
|
CP0482048
|
3-[4-[[3-[4-(2-ethylsulfonylethoxy)-2,6-dimethylphenyl]phenyl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
|
C28H31FO6S
|
2
|
| 1 |
EC50 = 25 nM
|
|
|
| 2 |
Ki = 15 nM
|
|
|
|
CP0531316
|
3-[4-[[3-(3,5-dimethyl-1,2-oxazol-4-yl)-4-fluorophenyl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
|
C21H19F2NO4
|
1
|
| 1 |
EC50 = 25.2 nM
|
|
|
|
CP0407487
|
3-[4-[[3-(3,5-dimethyl-1,2-oxazol-4-yl)-2-fluorophenyl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
|
C21H19F2NO4
|
1
|
| 1 |
EC50 = 25.9 nM
|
|
|
|
CP0921205
|
3-[4-({[4'-(2-Ethoxyethoxy)-2',6'-dimethylbiphenyl-3-yl]-methyl}amino)-2-fluorophenyl]propanoic Acid Hydrochloride
Show/Hide
|
C28H33ClFNO4
|
2
|
| 1 |
EC50 = 26 nM
|
|
|
| 2 |
Ki = 18 nM
|
|
|
|
CP0563069
|
3-cyclopropyl-3-[3-[[1-[2-[2,2-dimethylpropyl(pyridin-2-yl)carbamoyl]-5-methoxyphenyl]piperidin-4-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C36H45N3O5
|
1
|
| 1 |
EC50 = 26 nM
|
|
|
|
CP0372137
|
3-{4-[(2'-Methylbiphenyl-3-yl)methoxy]phenyl}propanic Acid
Show/Hide
|
C23H22O3
|
1
|
| 1 |
EC50 = 27 nM
|
|
|
|
CP0388790
|
3-[4-[(3,4-dichlorophenyl)methylamino]phenyl]-3-ethoxypropanoic acid
Show/Hide
|
C18H19Cl2NO3
|
1
|
| 1 |
EC50 = 27 nM
|
|
|
|
CP0567119
|
2-[6-[[3-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C22H21NO5
|
1
|
| 1 |
EC50 = 27.5 nM
|
|
|
|
CP0389851
|
2-[6-[[3-[4-(2-ethoxyethoxy)-2,6-dimethylphenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C29H32O6
|
3
|
| 1 |
EC50 = 28 nM
|
|
|
| 2 |
EC50 = 30 nM
|
|
|
| 3 |
Ki = 32 nM
|
|
|
|
CP0430591
|
2-[6-[[3-(2,6-dimethyl-4-phenylmethoxyphenyl)phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C32H30O5
|
2
|
| 1 |
EC50 = 28 nM
|
|
|
| 2 |
Ki = 18 nM
|
|
|
|
CP0377613
|
2-[5-[[3-(2,6-dimethylphenyl)phenyl]methoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Show/Hide
|
C26H26O3
|
3
|
| 1 |
EC50 = 28 nM
|
|
|
| 2 |
EC50 = 33 nM
|
|
|
| 3 |
Ki = 210 nM
|
|
|
|
CP0402769
|
2-[4-[[3-(2-chlorophenyl)phenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
|
C21H17ClO5S
|
1
|
| 1 |
EC50 = 28.84 nM
|
|
|
|
CP0417303
|
2-[6-[[3-(2,4-dimethylphenyl)phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C25H24O4
|
2
|
| 1 |
EC50 = 29 nM
|
|
|
| 2 |
Ki = 57 nM
|
|
|
|
CP0507689
|
3-[2-fluoro-4-[[3-[4-[(4-hydroxy-1,1-dioxothian-4-yl)methoxy]-2,6-dimethylphenyl]phenyl]methylamino]phenyl]propanoic acid
Show/Hide
|
C30H34FNO6S
|
2
|
| 1 |
EC50 = 29 nM
|
|
|
| 2 |
Ki = 19 nM
|
|
|
|
CP0461989
|
2-[(3S)-6-[[3-[4-(1,1-dioxothian-4-yl)oxy-2,3,5,6-tetramethylphenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C32H36O7S
|
2
|
| 1 |
EC50 = 29 nM
|
|
|
| 2 |
Ki = 40 nM
|
|
|
|
CP0431838
|
(3S)-3-ethoxy-3-[4-[[(1R)-4-methyl-2,3-dihydro-1H-inden-1-yl]oxy]phenyl]propanoic acid
Show/Hide
|
C21H24O4
|
1
|
| 1 |
EC50 = 29 nM
|
|
|
|
CP0561198
|
3-cyclopropyl-3-[3-[[1-[5-methoxy-2-[2-methylpropyl(pyridin-2-yl)carbamoyl]phenyl]piperidin-4-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C35H43N3O5
|
1
|
| 1 |
EC50 = 29 nM
|
|
|
|
CP0404983
|
3-{4-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]-2-methylphenyl}propanoic Acid
Show/Hide
|
C25H26O3
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0441391
|
3-(4-{[2'-(1-Methylethyl)biphenyl-3-yl]methoxy}phenyl)-propanoic Acid
Show/Hide
|
C25H26O3
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0479889
|
3-{4-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]-2-methoxyphenyl}propanoic Acid
Show/Hide
|
C25H26O4
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0443035
|
3-ethoxy-3-[4-[(3-fluorophenyl)methoxy]phenyl]propanoic acid
Show/Hide
|
C18H19FO4
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0477310
|
2-[(3S,8S)-3-[3-(2,6-dimethylphenyl)phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C26H24O5
|
1
|
| 1 |
EC50 = 30.1 nM
|
|
|
|
CP0374971
|
2-[(3S,8S)-3-[3-(trifluoromethyl)phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C19H15F3O5
|
1
|
| 1 |
EC50 = 30.4 nM
|
|
|
|
CP0486834
|
3-(4-((R)-2,3-dihydro-1H-inden-1-yloxy)phenyl)hex-4-ynoic acid
Show/Hide
|
C21H20O3
|
2
|
| 1 |
EC50 = 31 nM
|
|
|
| 2 |
IC50 = 42 nM
|
|
|
|
CP0876321
|
3-[4-({2',6'-Dimethyl-4'-[(6-methylpyridin-2-yl)oxy]-biphenyl-3-yl}methoxy)-2-fluorophenyl]propanoic Acid Hydrochloride
Show/Hide
|
C30H29ClFNO4
|
2
|
| 1 |
EC50 = 31 nM
|
|
|
| 2 |
Ki = 12 nM
|
|
|
|
CP0431839
|
(3S)-3-[4-[[(1R)-2,3-dihydro-1H-inden-1-yl]oxy]phenyl]-3-ethoxypropanoic acid
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C20H22O4
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1
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| 1 |
EC50 = 31 nM
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CP0511805
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3-{4-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]phenyl}butanoic Acid
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C25H26O3
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1
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| 1 |
EC50 = 32 nM
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CP0484139
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3-[4-[[3-[2,6-dimethyl-4-[3-(2-oxopyrrolidin-1-yl)propoxy]phenyl]phenyl]methoxy]-2-fluorophenyl]propanoic acid
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C31H34FNO5
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2
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| 1 |
EC50 = 32 nM
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| 2 |
Ki = 21 nM
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CP0408053
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3-[5-[[3-(2,6-dimethylphenyl)phenyl]methoxy]thiophen-2-yl]propanoic acid
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C22H22O3S
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2
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| 1 |
EC50 = 32 nM
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| 2 |
EC50 = 52 nM
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CP0433253
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2-[6-[[3-(2,4,6-trimethylphenyl)phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
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C26H26O4
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2
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| 1 |
EC50 = 33 nM
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| 2 |
Ki = 36 nM
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CP0048375
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(3S)-3-[4-[[3-(4-chloro-2-methylphenyl)phenyl]methoxy]phenyl]-3-(1-methylimidazol-2-yl)propanoic acid
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C27H25ClN2O3
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2
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| 1 |
EC50 = 33 nM
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| 2 |
EC50 = 10000 nM
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CP0395592
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(3S)-3-[4-[[3-(4-chloro-2-methylphenyl)phenyl]methoxy]phenyl]-3-(2-methyl-1,2,4-triazol-3-yl)propanoic acid
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C26H24ClN3O3
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1
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| 1 |
EC50 = 33 nM
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CP0566009
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3-[4-[[3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-fluorophenyl]methoxy]-2-fluorophenyl]propanoic acid
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C21H19F2NO4
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1
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| 1 |
EC50 = 33.2 nM
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CP0404981
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3-{4-[(3-Phenoxybenzyl)oxy]phenyl}propanoic Acid
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C22H20O4
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1
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| 1 |
EC50 = 34 nM
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CP0532788
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3-cyclopropyl-3-[3-[[1-[2-(3,3-dimethylbutyl)-5-methoxyphenyl]piperidin-4-yl]methoxy]phenyl]propanoic acid
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C31H43NO4
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1
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| 1 |
EC50 = 34 nM
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CP0055615
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2-[(3R,8S)-3-(3-chlorophenyl)-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
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C18H15ClO5
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1
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| 1 |
EC50 = 34.2 nM
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CP0544717
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2-[6-[[3-(2,5-dimethylpyrrol-1-yl)-4-methoxyphenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
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C24H25NO5
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1
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| 1 |
EC50 = 34.7 nM
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CP0378804
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3-{4-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]-2,6-difluorophenyl}propanoic Acid
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C24H22F2O3
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1
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| 1 |
EC50 = 35 nM
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CP0388789
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3-ethoxy-3-[4-[(3-methylphenyl)methoxy]phenyl]propanoic acid
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C19H22O4
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1
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| 1 |
EC50 = 35 nM
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CP0443034
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3-[4-(cyclohexylmethoxy)phenyl]-3-ethoxypropanoic acid
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C18H26O4
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1
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| 1 |
EC50 = 35 nM
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CP0433637
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2-[(8S)-3-[3-(4-fluoro-2-methylphenyl)phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
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C25H21FO5
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1
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| 1 |
EC50 = 35.9 nM
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CP0308563
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(3S)-3-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methoxy]phenyl]-3-(1,2-oxazol-3-yl)propanoic acid
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C24H19F3N2O4S
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1
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| 1 |
EC50 = 36 nM
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CP0439939
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(3S)-3-[4-[[3-(4-chloro-2-methylphenyl)phenyl]methoxy]phenyl]hex-4-ynoic acid
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C26H23ClO3
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1
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| 1 |
EC50 = 36 nM
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CP0468120
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(3S)-3-ethoxy-3-[6-[[(3S)-7-(trifluoromethyl)-2,3-dihydro-1-benzofuran-3-yl]oxy]pyridin-3-yl]propanoic acid
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C19H18F3NO5
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1
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| 1 |
EC50 = 36 nM
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CP0420545
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(3S)-3-[4-[[3-(5-fluoro-2-methylphenyl)phenyl]methoxy]phenyl]-3-(1-methylimidazol-2-yl)propanoic acid
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C27H25FN2O3
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2
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| 1 |
EC50 = 36 nM
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| 2 |
EC50 = 42000 nM
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CP0432014
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2-[2-fluoro-4-[[3-[4-(2-hydroxyethoxy)-2-methylphenyl]phenyl]methylamino]phenoxy]acetic acid
Show/Hide
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C24H24FNO5
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1
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| 1 |
EC50 = 36.1 nM
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CP0486453
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(E)-3-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylamino]phenyl]prop-2-enoic acid
Show/Hide
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C21H17F3N2O2S
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1
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| 1 |
EC50 = 36.31 nM
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CP0538722
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2-[4-[[3-(2-chloro-4-methylphenyl)phenyl]methoxy]phenyl]sulfonylacetic acid
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C22H19ClO5S
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1
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| 1 |
EC50 = 36.31 nM
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CP0446277
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2-[(8S)-3-(3-cyclopropylphenyl)-2,3,7,8-tetrahydrofuro[3,2-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
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C21H20O5
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1
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| 1 |
EC50 = 36.4 nM
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CP0575249
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2-[2-fluoro-4-[[3-(2-fluorophenyl)phenyl]methylamino]phenoxy]acetic acid
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C21H17F2NO3
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1
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| 1 |
EC50 = 36.5 nM
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CP0459099
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3-[2-(3-chlorophenyl)-1H-indol-5-yl]propanoic acid
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C17H14ClNO2
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1
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| 1 |
EC50 = 37.8 nM
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CP0441388
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3-(4-{[3-(2-Methylphenoxy)benzyl]oxy}phenyl)propanoic Acid
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C23H22O4
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1
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| 1 |
EC50 = 38 nM
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CP0901039
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3-(4-((3-(3,5-dimethylisoxazol-4-yl)benzyl)oxy)phenyl)propanoic-2,2-d2 acid
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C21H21NO4
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1
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| 1 |
EC50 = 38.4 nM
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CP0482506
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2-[(8S)-3-[3-(2,4-dimethylphenyl)phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
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C26H24O5
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1
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| 1 |
EC50 = 38.7 nM
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CP0579005
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2-[4-[[3-(2,6-dimethyl-4-propoxyphenyl)phenyl]methylamino]-2-fluorophenoxy]acetic acid
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C26H28FNO4
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1
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| 1 |
EC50 = 38.7 nM
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CP0399436
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3-[4-[[3-chloro-5-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
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C21H19ClFNO4
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1
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| 1 |
EC50 = 38.9 nM
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CP0417305
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2-[6-[[3-(1-benzothiophen-3-yl)phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
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C25H20O4S
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2
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| 1 |
EC50 = 39 nM
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| 2 |
Ki = 290 nM
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CP0895810
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rac-[6-({4'-[(1,1-Dioxidotetrahydro-2H-thiopyran-4-yl)oxy]-2',6'-dimethylbiphenyl-3-yl}methoxy)-2,3-dihydro-1-benzofuran-3-yl]acetic Acid
Show/Hide
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C30H32O7S
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2
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| 1 |
EC50 = 39 nM
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| 2 |
Ki = 83 nM
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CP0396560
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2-[(3R,8S)-3-[3-(2-methylphenyl)phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
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C25H22O5
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1
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| 1 |
EC50 = 39.3 nM
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CP0489839
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2-[6-[[2-chloro-5-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
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C22H20ClNO5
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1
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| 1 |
EC50 = 39.7 nM
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CP0435720
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3-[4-[(3-phenoxyphenyl)methylamino]phenyl]-N-propan-2-ylpropanamide
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C25H28N2O2
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1
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| 1 |
EC50 = 39.81 nM
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CP0513032
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3-(4-{[3-(4-Methylphenoxy)benzyl]oxy}phenyl)propanoic Acid
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C23H22O4
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1
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| 1 |
EC50 = 40 nM
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CP0399442
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3-[4-[[3-(2,6-dimethylphenyl)-2-methylphenyl]methoxy]phenyl]propanoic acid
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C25H26O3
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2
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| 1 |
EC50 = 40 nM
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| 2 |
Ki = 58 nM
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CP0399023
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(3S)-3-(1-methyltetrazol-5-yl)-3-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methoxy]phenyl]propanoic acid
Show/Hide
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C23H20F3N5O3S
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1
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| 1 |
EC50 = 41 nM
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CP0559744
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2-[2-fluoro-4-[[3-(2-methyl-4-propoxyphenyl)phenyl]methylamino]phenoxy]acetic acid
Show/Hide
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C25H26FNO4
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1
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| 1 |
EC50 = 41.3 nM
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CP0477796
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(3S)-6-[[3-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-carboxylic acid
Show/Hide
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C28H30O7S
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1
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| 1 |
EC50 = 41.69 nM
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CP0455830
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2-[2-fluoro-4-[[3-[4-(2-methoxyethoxy)-2-methylphenyl]phenyl]methylamino]phenoxy]acetic acid
Show/Hide
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C25H26FNO5
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1
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| 1 |
EC50 = 41.9 nM
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CP0377836
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3-[4-(2-chloro-4-cyanophenoxy)phenyl]hex-4-ynoic acid
Show/Hide
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C19H14ClNO3
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2
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| 1 |
EC50 = 42 nM
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| 2 |
IC50 = 23 nM
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CP0403435
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(3S)-3-(1-methylimidazol-2-yl)-3-[4-[[3-(2-methylphenyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
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C27H26N2O3
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2
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| 1 |
EC50 = 43 nM
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| 2 |
EC50 = 89000 nM
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CP0531246
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(3S)-3-[4-[[3-(2-chlorophenyl)phenyl]methoxy]phenyl]-3-(1-methylimidazol-2-yl)propanoic acid
Show/Hide
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C26H23ClN2O3
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2
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| 1 |
EC50 = 43 nM
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| 2 |
EC50 = 56000 nM
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CP0380346
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2-[2-fluoro-4-[[3-[2-methyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]phenoxy]acetic acid
Show/Hide
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C26H27FO7S
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2
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| 1 |
EC50 = 43.6 nM
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| 2 |
EC50 = 61 nM
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CP0513034
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3-(4-{[3-(3-Methylphenoxy)benzyl]oxy}phenyl)propanoic Acid
Show/Hide
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C23H22O4
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1
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| 1 |
EC50 = 45 nM
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CP0576085
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2-[2-fluoro-4-[[3-[2-methyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methylamino]phenoxy]acetic acid
Show/Hide
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C26H28FNO6S
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1
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| 1 |
EC50 = 45.6 nM
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CP0876116
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3-(4-((3-(3,5-dimethylisoxazol-4-yl)benzyl)oxy)-2-fluorophenyl)propanoic-2,2-d2 acid
Show/Hide
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C21H20FNO4
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1
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| 1 |
EC50 = 45.7 nM
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CP0518182
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2-[(3R,8S)-3-[5-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]-2-fluorophenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
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C30H31FO8S
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1
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| 1 |
EC50 = 46.5 nM
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CP0564014
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2-[4-[[3-(2-methylphenyl)phenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
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C22H20O5S
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1
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| 1 |
EC50 = 46.77 nM
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CP0444102
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2-[6-[[3-(2,5-dimethylpyrrol-1-yl)phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
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C23H23NO4
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2
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| 1 |
EC50 = 46.9 nM
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| 2 |
EC50 = 53.6 nM
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CP0505718
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3-(4-{[3-(2,6-Dimethylphenoxy)benzyl]oxy}phenyl)propanoic Acid
Show/Hide
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C24H24O4
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1
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| 1 |
EC50 = 47 nM
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CP0864099
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[6-({[4'-(2-Ethoxyethoxy)-2',6'-dimethylbiphenyl-3-yl]methyl}amino)-2,3-dihydro-1-benzofuran-3-yl]acetic acid hydrochloride
Show/Hide
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C29H34ClNO5
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2
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| 1 |
EC50 = 48 nM
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| 2 |
Ki = 43 nM
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CP0377587
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(3S)-3-[4-[[3-(2-ethylphenyl)phenyl]methoxy]phenyl]-3-(1-methylimidazol-2-yl)propanoic acid
Show/Hide
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C28H28N2O3
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2
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| 1 |
EC50 = 48 nM
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| 2 |
EC50 = 65000 nM
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CP0428401
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2-[6-[[2-(4-fluorophenyl)-4-methyl-1,3-thiazol-5-yl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
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C21H18FNO4S
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2
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| 1 |
EC50 = 48.7 nM
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| 2 |
EC50 = 79 nM
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CP0441734
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N-methyl-3-[4-[(3-phenoxyphenyl)methylamino]phenyl]propanamide
Show/Hide
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C23H24N2O2
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1
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| 1 |
EC50 = 48.98 nM
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CP0408784
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8-[[3-(2,6-dimethylphenyl)phenyl]methoxy]-2,3,4,5-tetrahydro-1-benzoxepine-4-carboxylic acid
Show/Hide
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C26H26O4
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3
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| 1 |
EC50 = 49 nM
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| 2 |
EC50 = 70 nM
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| 3 |
Ki = 270 nM
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CP0400817
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2-[6-[[3-(2,6-dimethylphenyl)phenyl]methoxy]-1,3-dihydrofuro[3,4-c]pyridin-3-yl]acetic acid
Show/Hide
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C24H23NO4
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1
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| 1 |
EC50 = 49 nM
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CP0409597
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3-[4-(3,4-dichlorophenoxy)phenyl]-3-ethoxypropanoic acid
Show/Hide
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C17H16Cl2O4
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1
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| 1 |
EC50 = 49 nM
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CP0380348
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2-[2-fluoro-4-[[3-(4-methoxy-2,6-dimethylphenyl)phenyl]methoxy]phenoxy]acetic acid
Show/Hide
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C24H23FO5
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2
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| 1 |
EC50 = 49.7 nM
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| 2 |
EC50 = 54.2 nM
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CP0393671
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(3R)-3-[5-[[3-(2,6-dimethylphenyl)phenyl]methoxy]thiophen-2-yl]-3-ethoxypropanoic acid
Show/Hide
|
C24H26O4S
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1
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| 1 |
EC50 = 50 nM
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CP0483434
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3-[4-[[2-(4-methylphenyl)-4,5,6,7-tetrahydro-1,3-benzothiazol-7-yl]oxy]phenyl]hex-4-ynoic acid
Show/Hide
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C26H25NO3S
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2
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| 1 |
EC50 = 51 nM
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| 2 |
IC50 = 23 nM
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CP0441735
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3-[4-[(3-phenoxyphenyl)methylamino]phenyl]propanamide
Show/Hide
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C22H22N2O2
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1
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| 1 |
EC50 = 51.29 nM
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CP0564013
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2-[4-[[3-(2-chloro-4-ethoxyphenyl)phenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
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C23H21ClO6S
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1
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| 1 |
EC50 = 51.29 nM
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CP0521207
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2-[2-fluoro-4-[[3-[4-(2-methoxyethoxy)-2,6-dimethylphenyl]phenyl]methylamino]phenoxy]acetic acid
Show/Hide
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C26H28FNO5
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1
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| 1 |
EC50 = 51.6 nM
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CP0493541
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2-[4-[(4-chloro-3-phenylphenyl)methylamino]-2-fluorophenoxy]acetic acid
Show/Hide
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C21H17ClFNO3
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1
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| 1 |
EC50 = 51.7 nM
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CP0547294
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2-[4-[[3-[2-(trifluoromethyl)phenyl]phenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
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C22H17F3O5S
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1
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| 1 |
EC50 = 52.48 nM
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CP0396561
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2-[(3R,8S)-3-[3-(2,6-dimethylphenyl)phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C26H24O5
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1
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| 1 |
EC50 = 52.9 nM
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CP0438000
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3-[4-(4-cyanonaphthalen-1-yl)oxyphenyl]hex-4-ynoic acid
Show/Hide
|
C23H17NO3
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2
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| 1 |
EC50 = 53 nM
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| 2 |
IC50 = 13 nM
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CP0431844
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3-[4-[(3-cyanophenyl)methoxy]phenyl]-3-ethoxypropanoic acid
Show/Hide
|
C19H19NO4
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1
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| 1 |
EC50 = 53 nM
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CP0894394
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3-(4-((3-(3,5-dimethylisoxazol-4-yl)-5-methoxybenzyl)oxy)-2-fluorophenyl)propanoic acid
Show/Hide
|
C22H22FNO5
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1
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| 1 |
EC50 = 53.1 nM
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CP0486452
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(1S,2S)-2-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylamino]phenyl]-N-[(1R)-1-phenylethyl]cyclopropane-1-carboxamide
Show/Hide
|
C30H28F3N3OS
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1
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| 1 |
EC50 = 53.7 nM
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CP0489840
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2-[6-[[5-(3,5-dimethyl-1,2-oxazol-4-yl)-2-methylphenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C23H23NO5
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1
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| 1 |
EC50 = 53.7 nM
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CP0475601
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3-[2-(2-chlorophenyl)-1H-indol-5-yl]propanoic acid
Show/Hide
|
C17H14ClNO2
|
1
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| 1 |
EC50 = 54.6 nM
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CP0929214
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R/S-2-((8S)-3-(3-bromophenyl)-2,3,7,8-tetrahydrobenzofuro[5,6-b][1,4]dioxin-8-yl)acetic acid
Show/Hide
|
C18H15BrO5
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1
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| 1 |
EC50 = 54.7 nM
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CP0388929
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3-[4-[[4-[(4-benzyl-1-oxa-9-azaspiro[5.5]undecan-9-yl)methyl]phenyl]methoxy]phenyl]propanoic acid;hydrochloride
Show/Hide
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C33H40ClNO4
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1
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| 1 |
EC50 = 55 nM
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CP0393699
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2-[(3R,8S)-3-[3-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
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C30H32O8S
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1
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| 1 |
EC50 = 55.9 nM
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CP0446284
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2-[(8S)-3-[5-[2-chloro-4-(3-methylsulfonylpropoxy)phenyl]-2-fluorophenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
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C28H26ClFO8S
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1
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| 1 |
EC50 = 56.2 nM
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CP0380564
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2-[(3S,8S)-3-[3-(2-chlorophenyl)phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
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C24H19ClO5
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1
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| 1 |
EC50 = 56.7 nM
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CP0549684
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(3S)-3-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methoxy]phenyl]-3-(1,3-oxazol-5-yl)propanoic acid
Show/Hide
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C24H19F3N2O4S
|
1
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| 1 |
EC50 = 57 nM
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CP0420401
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3-[5-[[3-(2,6-dimethylphenyl)phenyl]methoxy]thiophen-2-yl]-3-ethoxypropanoic acid
Show/Hide
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C24H26O4S
|
1
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| 1 |
EC50 = 57 nM
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CP0545219
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2-[4-[[3-(4-methoxy-2,6-dimethylphenyl)phenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
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C24H24O6S
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1
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| 1 |
EC50 = 57.54 nM
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CP0439983
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3-[4-[(3-phenylphenyl)methoxy]phenyl]hex-4-ynoic acid
Show/Hide
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C25H22O3
|
1
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| 1 |
EC50 = 58 nM
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CP0078180
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3-[4-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methoxy]phenyl]propanoic acid
Show/Hide
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C20H19NO4
|
1
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| 1 |
EC50 = 58 nM
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CP0377586
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(3S)-3-[4-[[3-(2,6-dimethylphenyl)phenyl]methoxy]phenyl]-3-(1-methylimidazol-2-yl)propanoic acid
Show/Hide
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C28H28N2O3
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2
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| 1 |
EC50 = 58 nM
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| 2 |
EC50 = 29000 nM
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CP0579006
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2-[2-fluoro-4-[(3-phenylphenyl)methylamino]phenoxy]acetic acid
Show/Hide
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C21H18FNO3
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1
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| 1 |
EC50 = 58.5 nM
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CP0441501
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3-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylamino]phenyl]butanoic acid
Show/Hide
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C22H21F3N2O2S
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1
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| 1 |
EC50 = 58.88 nM
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CP0531245
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(3S)-3-[4-[[3-(4-fluoro-2-methylphenyl)phenyl]methoxy]phenyl]-3-(1-methylimidazol-2-yl)propanoic acid
Show/Hide
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C27H25FN2O3
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2
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| 1 |
EC50 = 59 nM
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| 2 |
EC50 = 21000 nM
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CP0455554
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2-[4-[[3-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methylamino]-2-fluorophenoxy]acetic acid
Show/Hide
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C27H30FNO6S
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1
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| 1 |
EC50 = 59.8 nM
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CP0447783
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(3S)-3-[4-[[3-(3-chloro-2-methylphenyl)phenyl]methoxy]phenyl]-3-(1-methylimidazol-2-yl)propanoic acid
Show/Hide
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C27H25ClN2O3
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2
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| 1 |
EC50 = 61 nM
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| 2 |
EC50 = 22000 nM
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CP0391616
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2-[6-[[3-(2,5-dimethylpyrrol-1-yl)-4-ethoxyphenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
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C25H27NO5
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1
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| 1 |
EC50 = 61.2 nM
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CP0560127
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2-[4-[[3-[2,6-dimethyl-4-(3-nitrooxypropoxy)phenyl]phenyl]methoxy]-2-fluorophenoxy]acetic acid
Show/Hide
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C26H26FNO8
|
1
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| 1 |
EC50 = 61.5 nM
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CP0380562
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2-[(8S)-3-[3-(2,4,6-trimethylphenyl)phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
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C27H26O5
|
1
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| 1 |
EC50 = 61.6 nM
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CP0404207
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(3S)-3-ethoxy-3-[4-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]oxy]phenyl]propanoic acid
Show/Hide
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C21H24O4
|
1
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| 1 |
EC50 = 62 nM
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CP0466395
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3-[3-[[1-[2-[2,2-dimethylpropyl-(6-methylpyridin-2-yl)carbamoyl]-5-methoxyphenyl]piperidin-4-yl]methoxy]phenyl]-3-methoxypropanoic acid
Show/Hide
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C35H45N3O6
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1
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| 1 |
EC50 = 62 nM
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CP0385936
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2-[4-[[3-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]-2-fluorophenoxy]acetic acid
Show/Hide
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C27H29FO7S
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1
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| 1 |
EC50 = 62.3 nM
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CP0500934
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(3S)-3-ethoxy-3-[4-[[(1R)-4-ethoxy-2,3-dihydro-1H-inden-1-yl]oxy]phenyl]propanoic acid
Show/Hide
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C22H26O5
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1
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| 1 |
EC50 = 63 nM
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CP0432421
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3-ethoxy-3-[4-[(3-nitrophenyl)methoxy]phenyl]propanoic acid
Show/Hide
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C18H19NO6
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1
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| 1 |
EC50 = 63 nM
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CP0550579
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2-[(3S)-5-[[3-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C29H32O7S
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1
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| 1 |
EC50 = 63 nM
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CP0545217
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2-[4-[[3-(4-ethoxy-2,6-dimethylphenyl)phenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
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C25H26O6S
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1
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| 1 |
EC50 = 63.1 nM
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CP0393698
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2-[(8S)-3-[3-fluoro-5-(trifluoromethyl)phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C19H14F4O5
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1
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| 1 |
EC50 = 63.7 nM
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CP0452170
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(3S)-3-[4-[(4-methoxyphenyl)methoxy]phenyl]hex-4-ynoic acid
Show/Hide
|
C20H20O4
|
1
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| 1 |
EC50 = 64 nM
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CP0428404
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2-[6-[[2-(3-fluorophenyl)-4-methyl-1,3-thiazol-5-yl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C21H18FNO4S
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1
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| 1 |
EC50 = 64.8 nM
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CP0510598
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3-[2-[[3-(2,6-dimethylphenyl)phenyl]methoxy]-1,3-thiazol-5-yl]propanoic acid
Show/Hide
|
C21H21NO3S
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1
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| 1 |
EC50 = 65 nM
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CP0539920
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3-[6-[[3-(2,6-dimethylphenyl)phenyl]methoxy]pyridin-3-yl]-2-methylpropanoic acid
Show/Hide
|
C24H25NO3
|
1
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| 1 |
EC50 = 65 nM
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CP0399024
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(3S)-3-(2-methyl-1,2,4-triazol-3-yl)-3-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C24H21F3N4O3S
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1
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| 1 |
EC50 = 65 nM
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CP0468121
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3-[4-[2-(3,4-dichlorophenyl)ethoxy]phenyl]-3-ethoxypropanoic acid
Show/Hide
|
C19H20Cl2O4
|
1
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| 1 |
EC50 = 65 nM
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CP0396559
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2-[(8S)-3-(3-phenylphenyl)-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C24H20O5
|
1
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| 1 |
EC50 = 65.4 nM
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CP0384798
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2-[4-[[3-(4-ethoxy-2,6-dimethylphenyl)phenyl]methoxy]-2-fluorophenoxy]acetic acid
Show/Hide
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C25H25FO5
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2
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| 1 |
EC50 = 65.9 nM
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| 2 |
EC50 = 69.3 nM
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CP0456856
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(1S,2S)-N,N-dimethyl-2-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylamino]phenyl]cyclopropane-1-carboxamide
Show/Hide
|
C24H24F3N3OS
|
1
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| 1 |
EC50 = 66.07 nM
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CP0477802
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2-[4-[[3-(2,6-dimethylphenyl)phenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
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C23H22O5S
|
1
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| 1 |
EC50 = 66.07 nM
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CP0396562
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2-[(3R,8S)-3-[3-(2-chlorophenyl)phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C24H19ClO5
|
1
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| 1 |
EC50 = 66.7 nM
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CP0482507
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2-[(3S,8S)-3-[5-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]-2-fluorophenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C30H31FO8S
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1
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| 1 |
EC50 = 67.5 nM
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CP0432474
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3-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylamino]phenyl]propanoic acid
Show/Hide
|
C21H19F3N2O2S
|
1
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| 1 |
EC50 = 67.61 nM
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CP0495087
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(3S)-3-cyclopropyl-3-[3-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(5-fluoro-2-methoxypyridin-4-yl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C32H36FNO4
|
1
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| 1 |
EC50 = 68 nM
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CP0479824
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2-[(3S)-6-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C22H18F3NO4S
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1
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| 1 |
EC50 = 68 nM
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CP0404682
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2-[6-[(4-methyl-2-thiophen-3-yl-1,3-thiazol-5-yl)methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C19H17NO4S2
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1
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| 1 |
EC50 = 68.5 nM
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CP0522506
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2-[3-[[3-(2,6-dimethylphenyl)phenyl]methoxy]-7-bicyclo[4.2.0]octa-1(6),2,4-trienyl]acetic acid
Show/Hide
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C25H24O3
|
2
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| 1 |
EC50 = 69 nM
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| 2 |
Ki = 1200 nM
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CP0546429
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(3S)-3-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methoxy]phenyl]-3-(1,3-oxazol-2-yl)propanoic acid
Show/Hide
|
C24H19F3N2O4S
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1
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| 1 |
EC50 = 69 nM
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CP0414597
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(3S)-3-[4-[[(1S)-2,3-dihydro-1H-inden-1-yl]oxy]phenyl]-3-ethoxypropanoic acid
Show/Hide
|
C20H22O4
|
1
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| 1 |
EC50 = 69 nM
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CP0390297
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(3S)-3-[4-[[3-(2,4-dichlorophenyl)phenyl]methoxy]phenyl]-3-(1-methylimidazol-2-yl)propanoic acid
Show/Hide
|
C26H22Cl2N2O3
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2
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| 1 |
EC50 = 69 nM
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| 2 |
EC50 = 30000 nM
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CP0885387
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3-(4-((3-(3,5-dimethylisoxazol-4-yl)-5-ethoxybenzyl)oxy)-2-fluorophenyl)propanoic acid
Show/Hide
|
C23H24FNO5
|
1
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| 1 |
EC50 = 69.1 nM
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CP0547297
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2-[4-[[3-(2,6-dimethyl-4-propoxyphenyl)phenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
|
C26H28O6S
|
1
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| 1 |
EC50 = 69.18 nM
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CP0482355
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2-[2-fluoro-4-[[3-(4-hydroxy-2-methylphenyl)phenyl]methylamino]phenoxy]acetic acid
Show/Hide
|
C22H20FNO4
|
1
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| 1 |
EC50 = 69.6 nM
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CP0164279
|
3-[4-[2-(difluoromethoxy)-4-(trifluoromethyl)phenoxy]phenyl]hex-4-ynoic acid
Show/Hide
|
C20H15F5O4
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2
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| 1 |
EC50 = 71 nM
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| 2 |
IC50 = 12 nM
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CP0384938
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3-[5-[[3-(2,6-dimethylphenyl)phenyl]methoxy]pyridin-2-yl]propanoic acid
Show/Hide
|
C23H23NO3
|
1
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| 1 |
EC50 = 71 nM
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CP0416012
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(3S)-3-(1-methylimidazol-2-yl)-3-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C25H22F3N3O3S
|
1
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| 1 |
EC50 = 73 nM
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CP0403900
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2-[(8S)-3-[3-(2-fluorophenyl)phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C24H19FO5
|
1
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| 1 |
EC50 = 73.2 nM
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CP0434421
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2-[6-[[4-methyl-2-(4-methylphenyl)-1,3-thiazol-5-yl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C22H21NO4S
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2
|
| 1 |
EC50 = 73.5 nM
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| 2 |
EC50 = 94 nM
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CP0532790
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3-[3-[[1-[2-[2,2-dimethylpropyl-(6-methylpyridin-2-yl)carbamoyl]-5-methoxyphenyl]piperidin-4-yl]methoxy]phenyl]-3-ethoxypropanoic acid
Show/Hide
|
C36H47N3O6
|
1
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| 1 |
EC50 = 74 nM
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CP0558105
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2-[4-[[3-(2-propan-2-ylphenyl)phenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
|
C24H24O5S
|
1
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| 1 |
EC50 = 74.13 nM
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CP0482505
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2-[(8S)-3-[3-[2-(trifluoromethyl)phenyl]phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C25H19F3O5
|
1
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| 1 |
EC50 = 74.5 nM
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CP0446279
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2-[(8S)-3-[3-(2-chloro-4-fluorophenyl)phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C24H18ClFO5
|
1
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| 1 |
EC50 = 74.7 nM
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CP0394481
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(3S)-3-cyclopropyl-3-[3-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C33H37FO4
|
2
|
| 1 |
EC50 = 76 nM
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| 2 |
EC50 = 80 nM
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CP0571862
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2-[4-[[3-[2,6-dimethyl-4-(2-nitrooxyethoxy)phenyl]phenyl]methoxy]-2-fluorophenoxy]acetic acid
Show/Hide
|
C25H24FNO8
|
1
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| 1 |
EC50 = 76.4 nM
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CP0456185
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3-[4-[[4-[[4-[(4-methylphenyl)methyl]-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;hydrochloride
Show/Hide
|
C34H42ClNO4
|
1
|
| 1 |
EC50 = 77 nM
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CP0894349
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3-(4-((3-(3,5-dimethylisoxazol-4-yl)-5-isopropoxybenzyl)oxy)-2-fluorophenyl)propanoic acid
Show/Hide
|
C24H26FNO5
|
1
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| 1 |
EC50 = 79.2 nM
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CP0564015
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2-[4-[[3-[4-(cyclopropylmethoxy)-2,6-dimethylphenyl]phenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
|
C27H28O6S
|
1
|
| 1 |
EC50 = 79.43 nM
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CP0523478
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(3R)-3-[3-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]pentanoic acid
Show/Hide
|
C32H37FO4
|
1
|
| 1 |
EC50 = 80 nM
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CP0102814
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(1'R,3R)-5-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]spiro[1,2-dihydroindene-3,2'-cyclopropane]-1'-carboxylic acid
Show/Hide
|
C33H35FO4
|
1
|
| 1 |
EC50 = 81 nM
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CP0483663
|
3-[6-[[3-(2,6-dimethylphenyl)phenyl]methoxy]-2-methylpyridin-3-yl]propanoic acid
Show/Hide
|
C24H25NO3
|
1
|
| 1 |
EC50 = 81 nM
|
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CP0420403
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(3R)-3-[5-[[3-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]thiophen-2-yl]hex-4-ynoic acid
Show/Hide
|
C29H32O6S2
|
1
|
| 1 |
EC50 = 81 nM
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CP0372131
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3-{4-[(2'-Methoxybiphenyl-3-yl)methoxy]phenyl}propanoic Acid
Show/Hide
|
C23H22O4
|
1
|
| 1 |
EC50 = 82 nM
|
|
|
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CP0389531
|
(3S)-3-[4-(2,3-dihydro-1H-inden-2-yloxy)phenyl]-3-ethoxypropanoic acid
Show/Hide
|
C20H22O4
|
2
|
| 1 |
EC50 = 82 nM
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|
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| 2 |
EC50 = 83 nM
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CP0517915
|
5-[[5-[[3-(2,6-dimethylphenyl)phenyl]methoxy]thiophen-2-yl]methyl]-1,3-thiazolidine-2,4-dione
Show/Hide
|
C23H21NO3S2
|
1
|
| 1 |
EC50 = 82 nM
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CP0446283
|
2-[(3R,8S)-3-[3-[3-fluoro-2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C30H31FO8S
|
1
|
| 1 |
EC50 = 82.4 nM
|
|
|
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CP0466397
|
(3R)-3-cyclopropyl-3-[2-[[1-[2-[2,2-dimethylpropyl-(6-methylpyridin-2-yl)carbamoyl]-5-methoxyphenyl]piperidin-4-yl]methoxy]pyridin-4-yl]propanoic acid
Show/Hide
|
C36H46N4O5
|
1
|
| 1 |
EC50 = 83 nM
|
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CP0381001
|
2-[5-[[3-[4-(2-ethoxyethoxy)-2,6-dimethylphenyl]phenyl]methoxy]-2,3-dihydro-1H-inden-2-yl]acetic acid
Show/Hide
|
C30H34O5
|
2
|
| 1 |
EC50 = 84 nM
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|
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| 2 |
Ki = 270 nM
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CP0437999
|
3-[4-(2-bromo-4-cyanophenoxy)phenyl]hex-4-ynoic acid
Show/Hide
|
C19H14BrNO3
|
2
|
| 1 |
EC50 = 85 nM
|
|
|
| 2 |
IC50 = 36 nM
|
|
|
|
CP0428403
|
2-[6-[[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C21H18ClNO4S
|
2
|
| 1 |
EC50 = 85.6 nM
|
|
|
| 2 |
EC50 = 105 nM
|
|
|
|
CP0475564
|
2-[2-fluoro-4-[[3-(2-propan-2-ylphenyl)phenyl]methylamino]phenoxy]acetic acid
Show/Hide
|
C24H24FNO3
|
1
|
| 1 |
EC50 = 86.2 nM
|
|
|
|
CP0403904
|
2-[(8S)-3-[3-(2,5-dimethylphenyl)phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C26H24O5
|
1
|
| 1 |
EC50 = 88 nM
|
|
|
|
CP0413154
|
(3S)-3-cyclopropyl-3-[3-[[3-(2,2-dimethylpropyl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C31H35FO4
|
1
|
| 1 |
EC50 = 88 nM
|
|
|
|
CP0541356
|
3-ethoxy-3-[4-[(3-methoxyphenyl)methoxy]phenyl]propanoic acid
Show/Hide
|
C19H22O5
|
1
|
| 1 |
EC50 = 89 nM
|
|
|
|
CP0965878
|
3-(4-((3-butoxy-5-(3,5-dimethylisoxazol-4-yl)benzyl)oxy)-2-fluorophenyl)propanoic acid
Show/Hide
|
C25H28FNO5
|
1
|
| 1 |
EC50 = 89.3 nM
|
|
|
|
CP0489817
|
(3S)-3-cyclobutyl-3-[3-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C34H39FO4
|
1
|
| 1 |
EC50 = 90 nM
|
|
|
|
CP0516371
|
(3R)-3-[3-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]-5-fluorophenyl]pentanoic acid
Show/Hide
|
C32H36F2O4
|
1
|
| 1 |
EC50 = 90 nM
|
|
|
|
CP0963271
|
3-(4-((3-(cyclopropylmethoxy)-5-(3,5-dimethylisoxazol-4-yl)benzyl)oxy)-2-fluorophenyl)propanoic acid
Show/Hide
|
C25H26FNO5
|
1
|
| 1 |
EC50 = 90.9 nM
|
|
|
|
CP0381002
|
2-[5-[[3-[4-(2-ethoxyethoxy)-2,6-dimethylphenyl]phenyl]methoxy]-1,3-dihydro-2-benzofuran-1-yl]acetic acid
Show/Hide
|
C29H32O6
|
2
|
| 1 |
EC50 = 91 nM
|
|
|
| 2 |
Ki = 390 nM
|
|
|
|
CP0397567
|
(1'R,4R)-6-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]spiro[2,3-dihydro-1H-naphthalene-4,2'-cyclopropane]-1'-carboxylic acid
Show/Hide
|
C34H37FO4
|
1
|
| 1 |
EC50 = 92 nM
|
|
|
|
CP0474292
|
2-[2-chloro-4-[[3-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]phenoxy]acetic acid
Show/Hide
|
C27H29ClO7S
|
1
|
| 1 |
EC50 = 92.6 nM
|
|
|
|
CP0414781
|
(3S)-3-cyclopropyl-3-[3-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(5-fluoro-2-methoxypyridin-4-yl)phenyl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
|
C32H35F2NO4
|
1
|
| 1 |
EC50 = 93 nM
|
|
|
|
CP0564160
|
2-[4-[[3-[2,6-dimethyl-4-(4-nitrooxybutoxy)phenyl]phenyl]methoxy]-2-fluorophenoxy]acetic acid
Show/Hide
|
C27H28FNO8
|
1
|
| 1 |
EC50 = 93.7 nM
|
|
|
|
CP0483435
|
3-[4-[2-methyl-4-(trifluoromethyl)phenoxy]phenyl]hex-4-ynoic acid
Show/Hide
|
C20H17F3O3
|
2
|
| 1 |
EC50 = 94 nM
|
|
|
| 2 |
IC50 = 40 nM
|
|
|
|
CP0433640
|
2-[(3R,8S)-3-[3-[2-chloro-4-(3-methylsulfonylpropoxy)phenyl]phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C28H27ClO8S
|
1
|
| 1 |
EC50 = 94.8 nM
|
|
|
|
CP0538724
|
2-[4-[[3-[2,6-dimethyl-4-(2-methylpropoxy)phenyl]phenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
|
C27H30O6S
|
1
|
| 1 |
EC50 = 95.5 nM
|
|
|
|
CP0459822
|
2-[6-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C22H18F3NO4S
|
2
|
| 1 |
EC50 = 96.7 nM
|
|
|
| 2 |
EC50 = 113 nM
|
|
|
|
CP0850431
|
3-(4-((3-(3,5-dimethylisoxazol-4-yl)-5-propoxybenzyl)oxy)-2-fluorophenyl)propanoic acid
Show/Hide
|
C24H26FNO5
|
1
|
| 1 |
EC50 = 96.7 nM
|
|
|
|
CP0377588
|
(3S)-3-[4-[[3-(4-chloro-2-methylphenyl)-4-methylphenyl]methoxy]phenyl]-3-(1-methylimidazol-2-yl)propanoic acid
Show/Hide
|
C28H27ClN2O3
|
2
|
| 1 |
EC50 = 97 nM
|
|
|
| 2 |
EC50 = 9800 nM
|
|
|
|
CP0558107
|
2-[4-[(3-phenoxyphenyl)methoxy]phenyl]sulfonylacetic acid
Show/Hide
|
C21H18O6S
|
1
|
| 1 |
EC50 = 97.72 nM
|
|
|
|
CP0381242
|
(1'R,4R)-6-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]-5-fluorospiro[2,3-dihydro-1H-naphthalene-4,2'-cyclopropane]-1'-carboxylic acid
Show/Hide
|
C34H36F2O4
|
1
|
| 1 |
EC50 = 98 nM
|
|
|
|
CP0431508
|
3-[2-chloro-4-[(3,4-dichlorophenyl)methoxy]phenyl]-3-ethoxypropanoic acid
Show/Hide
|
C18H17Cl3O4
|
1
|
| 1 |
EC50 = 98 nM
|
|
|
|
CP0431960
|
3-[4-[[3-[4-(2-ethylsulfonylethoxy)-2,6-dimethylphenyl]phenyl]methylamino]-2-fluorophenyl]propanoic acid
Show/Hide
|
C28H32FNO5S
|
2
|
| 1 |
EC50 = 99 nM
|
|
|
| 2 |
Ki = 20 nM
|
|
|
|
CP0432471
|
2-methyl-3-[4-[(3-phenoxyphenyl)methylamino]phenyl]propanoic acid
Show/Hide
|
C23H23NO3
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0435723
|
3-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylamino]phenyl]-N-propan-2-ylpropanamide
Show/Hide
|
C24H26F3N3OS
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0574385
|
3-ethoxy-3-[4-[[3-(methoxymethoxy)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C20H24O6
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0489818
|
(3S)-3-cyclopropyl-3-[3-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
|
C33H36F2O4
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0556651
|
(3R)-4-cyclopropyl-3-[3-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]butanoic acid
Show/Hide
|
C34H39FO4
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0466393
|
3-cyclopropyl-3-[3-[[1-[2-[2,2-dimethylpropyl(methyl)carbamoyl]-5-methoxyphenyl]piperidin-4-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C32H44N2O5
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0561157
|
3-cyclopropyl-3-[3-[[1-[5-methoxy-2-[(2-methoxy-2-methylpropyl)-pyridin-2-ylcarbamoyl]phenyl]piperidin-4-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C36H45N3O6
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0385020
|
3-[4-[[3-cyclopentyloxy-5-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
|
C26H28FNO5
|
1
|
| 1 |
EC50 = 102 nM
|
|
|
|
CP0459821
|
2-[6-[(4-methyl-2-phenyl-1,3-thiazol-5-yl)methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C21H19NO4S
|
1
|
| 1 |
EC50 = 102 nM
|
|
|
|
CP0380347
|
2-[2-fluoro-4-[[3-[4-(2-methoxyethoxy)-2,6-dimethylphenyl]phenyl]methoxy]phenoxy]acetic acid
Show/Hide
|
C26H27FO6
|
1
|
| 1 |
EC50 = 103.6 nM
|
|
|
|
CP0470695
|
2-[6-[[3-(1,3,5-trimethylpyrazol-4-yl)phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C23H24N2O4
|
1
|
| 1 |
EC50 = 103.7 nM
|
|
|
|
CP0057196
|
(1'R,4R)-6-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(5-fluoro-2-methoxypyridin-4-yl)phenyl]methoxy]-5-fluorospiro[2,3-dihydro-1H-naphthalene-4,2'-cyclopropane]-1'-carboxylic acid
Show/Hide
|
C33H35F2NO4
|
1
|
| 1 |
EC50 = 105 nM
|
|
|
|
CP0524464
|
(3S)-3-cyclopropyl-3-[3-[[3-[(1R)-1-fluoro-2,2-dimethylpropyl]-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C31H34F2O4
|
1
|
| 1 |
EC50 = 105 nM
|
|
|
|
CP0446276
|
2-[(8S)-3-(3-bromo-5-fluorophenyl)-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C18H14BrFO5
|
1
|
| 1 |
EC50 = 105.1 nM
|
|
|
|
CP0468582
|
2-[4-[[3-(2,6-dimethyl-4-propoxyphenyl)phenyl]methoxy]-2-fluorophenoxy]acetic acid
Show/Hide
|
C26H27FO5
|
1
|
| 1 |
EC50 = 105.8 nM
|
|
|
|
CP0377859
|
3-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenyl]hex-4-ynoic acid
Show/Hide
|
C18H13ClF3NO3
|
2
|
| 1 |
EC50 = 108 nM
|
|
|
| 2 |
IC50 = 30 nM
|
|
|
|
CP0492859
|
(3S)-3-cyclopropyl-3-[2-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(5-fluoro-2-methoxypyridin-4-yl)phenyl]methoxy]pyridin-4-yl]propanoic acid
Show/Hide
|
C31H35FN2O4
|
1
|
| 1 |
EC50 = 108 nM
|
|
|
|
CP0530325
|
2-[2-fluoro-4-[[2-(3-methylphenoxy)acetyl]amino]phenoxy]acetic acid
Show/Hide
|
C17H16FNO5
|
1
|
| 1 |
EC50 = 108.2 nM
|
|
|
|
CP0481732
|
2-[2-fluoro-4-[[3-[4-(3-hydroxypropoxy)-2,6-dimethylphenyl]phenyl]methoxy]phenoxy]acetic acid
Show/Hide
|
C26H27FO6
|
1
|
| 1 |
EC50 = 109.5 nM
|
|
|
|
CP0504078
|
3-[4-[(3-methoxyphenyl)methoxy]phenyl]hex-4-ynoic acid
Show/Hide
|
C20H20O4
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0393673
|
3-cyano-3-[5-[[3-(2,6-dimethylphenyl)phenyl]methoxy]thiophen-2-yl]propanoic acid
Show/Hide
|
C23H21NO3S
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0392462
|
(3R)-3-[3-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]hexanoic acid
Show/Hide
|
C33H39FO4
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0456225
|
2-[2-fluoro-4-[[3-(4-hydroxy-2,6-dimethylphenyl)phenyl]methoxy]phenoxy]acetic acid
Show/Hide
|
C23H21FO5
|
1
|
| 1 |
EC50 = 110.3 nM
|
|
|
|
CP0477309
|
2-[(3S,8S)-3-(3-bromophenyl)-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C18H15BrO5
|
1
|
| 1 |
EC50 = 111.1 nM
|
|
|
|
CP0429751
|
(3S)-3-(1-methylimidazol-2-yl)-3-[4-[[3-[2-(trifluoromethoxy)phenyl]phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C27H23F3N2O4
|
2
|
| 1 |
EC50 = 112 nM
|
|
|
| 2 |
EC50 = 61000 nM
|
|
|
|
CP0552693
|
2-[2-fluoro-4-[[2-(4-fluorophenyl)-4-methyl-1,3-thiazol-5-yl]methoxy]phenoxy]acetic acid
Show/Hide
|
C19H15F2NO4S
|
1
|
| 1 |
EC50 = 112 nM
|
|
|
|
CP0271790
|
3-[4-[2-(difluoromethoxy)-4-(trifluoromethyl)phenoxy]-2-fluorophenyl]hex-4-ynoic acid
Show/Hide
|
C20H14F6O4
|
2
|
| 1 |
EC50 = 113 nM
|
|
|
| 2 |
IC50 = 49 nM
|
|
|
|
CP0483792
|
3-(4-cyclopentyloxyphenyl)hex-4-ynoic acid
Show/Hide
|
C17H20O3
|
2
|
| 1 |
EC50 = 114 nM
|
|
|
| 2 |
IC50 = 312 nM
|
|
|
|
CP0492857
|
(3S)-3-cyclopropyl-3-[3-[[3-[(1R)-1-ethoxy-2,2-dimethylpropyl]-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C33H39FO5
|
1
|
| 1 |
EC50 = 114 nM
|
|
|
|
CP0510590
|
3-[4-[[3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-(trifluoromethyl)phenyl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
|
C22H19F4NO4
|
1
|
| 1 |
EC50 = 114 nM
|
|
|
|
CP0441746
|
3-[4-[(3-phenoxyphenyl)methylamino]phenyl]-1-pyrrolidin-1-ylpropan-1-one
Show/Hide
|
C26H28N2O2
|
1
|
| 1 |
EC50 = 114.82 nM
|
|
|
|
CP0431342
|
2-[2-fluoro-4-[[2-(3-propan-2-ylphenoxy)acetyl]amino]phenoxy]acetic acid
Show/Hide
|
C19H20FNO5
|
1
|
| 1 |
EC50 = 115.6 nM
|
|
|
|
CP0428402
|
2-[6-[[4-methyl-2-(3-methylphenyl)-1,3-thiazol-5-yl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C22H21NO4S
|
1
|
| 1 |
EC50 = 118.5 nM
|
|
|
|
CP0478589
|
3-{4-[(4'-Methylbiphenyl-3-yl)methoxy]phenyl}propanoic Acid
Show/Hide
|
C23H22O3
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0505719
|
3-{4-[(2'-Fluorobiphenyl-3-yl)methoxy]phenyl}propanoic Acid
Show/Hide
|
C22H19FO3
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0504034
|
3-[4-[(4-methoxyphenyl)methoxy]phenyl]-5-methylhex-4-enoic acid
Show/Hide
|
C21H24O4
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0415633
|
(3S)-3-cyclopropyl-3-[3-[[3-(5,5-dimethylcyclopenten-1-yl)-4-(5-fluoro-2-methoxypyridin-4-yl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C32H34FNO4
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0384939
|
3-[6-[[3-(2,6-dimethylphenyl)phenyl]methoxy]pyridin-3-yl]-2-methoxypropanoic acid
Show/Hide
|
C24H25NO4
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0484560
|
(3S)-3-ethoxy-3-[4-[(7-methyl-1,2-benzoxazol-3-yl)oxy]phenyl]propanoic acid
Show/Hide
|
C19H19NO5
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0567373
|
3-(1,3-thiazol-2-yl)-3-[4-[[3-[4-(trifluoromethyl)phenyl]phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C26H20F3NO3S
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0556649
|
(3R)-3-[3-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]-2-fluorophenyl]pentanoic acid
Show/Hide
|
C32H36F2O4
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0532787
|
3-cyclopropyl-3-[3-[[1-(5-methoxy-2-propan-2-ylphenyl)piperidin-4-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C28H37NO4
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0563071
|
3-[3-[[1-[2-[2,2-dimethylpropyl-(6-methylpyridin-2-yl)carbamoyl]-5-methoxyphenyl]piperidin-4-yl]methoxy]phenyl]-4-methoxybutanoic acid
Show/Hide
|
C36H47N3O6
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0449557
|
2-[(3S,8S)-3-[3-[3-fluoro-2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C30H31FO8S
|
1
|
| 1 |
EC50 = 120.7 nM
|
|
|
|
CP0424278
|
2-[4-[[3-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]phenoxy]acetic acid
Show/Hide
|
C27H30O7S
|
1
|
| 1 |
EC50 = 121.1 nM
|
|
|
|
CP0471681
|
2-[4-[[2-(3-tert-butylphenoxy)acetyl]amino]-2-fluorophenoxy]acetic acid
Show/Hide
|
C20H22FNO5
|
1
|
| 1 |
EC50 = 121.7 nM
|
|
|
|
CP0396563
|
2-[(8S)-3-[3-[2-methyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C29H30O8S
|
1
|
| 1 |
EC50 = 122.6 nM
|
|
|
|
CP0477793
|
2-[6-[[3-(4-methoxy-2,6-dimethylphenyl)phenyl]methoxy]-2,3-dihydro-1-benzothiophen-3-yl]acetic acid
Show/Hide
|
C26H26O4S
|
1
|
| 1 |
EC50 = 123.03 nM
|
|
|
|
CP0404688
|
2-[6-[[2-(4-methoxyphenyl)-4-methyl-1,3-thiazol-5-yl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C22H21NO5S
|
2
|
| 1 |
EC50 = 123.4 nM
|
|
|
| 2 |
EC50 = 156 nM
|
|
|
|
CP0915404
|
rac-5-(1-(4-(2-(difluoromethoxy)-4-(trifluoromethyl)phenoxy)phenyl)but-2-ynyl)oxazolidine-2,4-dione
Show/Hide
|
C21H14F5NO5
|
2
|
| 1 |
EC50 = 124 nM
|
|
|
| 2 |
IC50 = 19 nM
|
|
|
|
CP0446282
|
2-[(8S)-3-[3-[2-chloro-4-(3-methylsulfonylpropoxy)phenyl]-4-fluorophenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
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C28H26ClFO8S
|
1
|
| 1 |
EC50 = 125 nM
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CP0456853
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3-[4-[(3-phenoxyphenyl)methylamino]phenyl]butanoic acid
Show/Hide
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C23H23NO3
|
1
|
| 1 |
EC50 = 125.89 nM
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CP0415870
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2-[4-[[3-[4-(2-methoxyethoxy)-2,6-dimethylphenyl]phenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
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C26H28O7S
|
1
|
| 1 |
EC50 = 125.89 nM
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CP0396858
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2-[(1R)-6-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(5-fluoro-2-methoxypyridin-4-yl)phenyl]methoxy]-1-methyl-2,3-dihydroinden-1-yl]acetic acid
Show/Hide
|
C32H36FNO4
|
1
|
| 1 |
EC50 = 128 nM
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CP0415877
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2-[4-[[3-(2,5-dimethylpyrrol-1-yl)phenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
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C21H21NO5S
|
1
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| 1 |
EC50 = 128.82 nM
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CP0654587
|
cis-rac-5-(1-(4-(2-(difluoromethoxy)-4-(trifluoromethyl)phenoxy)phenyl)but-2-ynyl)oxazolidine-2,4-dione
Show/Hide
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C21H14F5NO5
|
2
|
| 1 |
EC50 = 130 nM
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| 2 |
IC50 = 151 nM
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CP0556693
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3-[2-[[3-(2,6-dimethylphenyl)phenyl]methoxy]pyrimidin-5-yl]propanoic acid
Show/Hide
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C22H22N2O3
|
1
|
| 1 |
EC50 = 130 nM
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CP0377590
|
3-(1-methylimidazol-2-yl)-3-[4-[[3-[4-(trifluoromethyl)phenyl]phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C27H23F3N2O3
|
1
|
| 1 |
EC50 = 130 nM
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CP0446281
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2-[(8S)-3-[3-(3,5-dimethylphenyl)phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C26H24O5
|
1
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| 1 |
EC50 = 132 nM
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CP0436274
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2-[4-[2-(3,4-dimethylphenoxy)propanoylamino]-2-fluorophenoxy]acetic acid
Show/Hide
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C19H20FNO5
|
1
|
| 1 |
EC50 = 132.9 nM
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CP0478656
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2-[2-fluoro-4-(2-phenoxypropanoylamino)phenoxy]acetic acid
Show/Hide
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C17H16FNO5
|
1
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| 1 |
EC50 = 135.3 nM
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CP0401500
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2-[2-fluoro-4-[2-(2-fluorophenoxy)propanoylamino]phenoxy]acetic acid
Show/Hide
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C17H15F2NO5
|
1
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| 1 |
EC50 = 135.9 nM
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CP0404686
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2-[6-[[2-(3-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C21H18ClNO4S
|
1
|
| 1 |
EC50 = 137.5 nM
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CP0389852
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6-[[3-[4-(2-ethoxyethoxy)-2,6-dimethylphenyl]phenyl]methoxy]-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid
Show/Hide
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C30H34O5
|
2
|
| 1 |
EC50 = 140 nM
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| 2 |
Ki = 280 nM
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CP0526727
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(3S)-3-cyclopropyl-3-[3-[[3-(2,2-dimethylcyclopentyl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C33H37FO4
|
1
|
| 1 |
EC50 = 140 nM
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CP0532786
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3-cyclopropyl-3-[3-[[1-[5-methoxy-2-[methyl(phenyl)carbamoyl]phenyl]piperidin-4-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C33H38N2O5
|
1
|
| 1 |
EC50 = 140 nM
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CP0415762
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2-[4-[2-(3-tert-butylphenoxy)propanoylamino]-2-fluorophenoxy]acetic acid
Show/Hide
|
C21H24FNO5
|
1
|
| 1 |
EC50 = 140.3 nM
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CP0885386
|
3-(4-((3-(3,5-dimethylisoxazol-4-yl)-5-isobutoxybenzyl)oxy)-2-fluorophenyl)propanoic acid
Show/Hide
|
C25H28FNO5
|
1
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| 1 |
EC50 = 143 nM
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CP0492617
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(E)-3-[4-[(3-phenoxyphenyl)methylamino]phenyl]prop-2-enoic acid
Show/Hide
|
C22H19NO3
|
1
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| 1 |
EC50 = 144.54 nM
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CP0477311
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2-[(3S,8S)-3-[3-[2-chloro-4-(3-methylsulfonylpropoxy)phenyl]phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C28H27ClO8S
|
1
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| 1 |
EC50 = 145.2 nM
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CP0401153
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(3S)-3-cyclopropyl-3-[3-[[4-(2-fluoro-5-methoxyphenyl)-3-[(1R)-1-methoxy-2,2-dimethylpropyl]phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C32H37FO5
|
1
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| 1 |
EC50 = 147 nM
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CP0442954
|
3-[3-[(3,4-dichlorophenyl)methoxy]phenyl]-3-ethoxypropanoic acid
Show/Hide
|
C18H18Cl2O4
|
1
|
| 1 |
EC50 = 147 nM
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CP0401501
|
2-[2-fluoro-4-[[2-(3-methoxyphenoxy)acetyl]amino]phenoxy]acetic acid
Show/Hide
|
C17H16FNO6
|
1
|
| 1 |
EC50 = 147.6 nM
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CP0411407
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2-[2-fluoro-4-[[2-(4-methylphenoxy)acetyl]amino]phenoxy]acetic acid
Show/Hide
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C17H16FNO5
|
1
|
| 1 |
EC50 = 148.2 nM
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CP0477341
|
2-[2-fluoro-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methoxy]phenoxy]acetic acid
Show/Hide
|
C20H15F4NO4S
|
1
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| 1 |
EC50 = 149 nM
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CP0479573
|
(1'R,4R)-6-[[3-(5,5-dimethylcyclopenten-1-yl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]spiro[2,3-dihydro-1H-naphthalene-4,2'-cyclopropane]-1'-carboxylic acid
Show/Hide
|
C34H35FO4
|
1
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| 1 |
EC50 = 150 nM
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CP0396859
|
(3R)-3-[2-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(5-fluoro-2-methoxypyridin-4-yl)phenyl]methoxy]pyridin-4-yl]pentanoic acid
Show/Hide
|
C30H35FN2O4
|
1
|
| 1 |
EC50 = 150 nM
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CP0064202
|
(3S)-3-cyclopropyl-3-[3-[[3-(5,5-dimethylcyclopenten-1-yl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C33H35FO4
|
5
|
| 1 |
EC50 = 150 nM
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|
|
| 2 |
EC50 = 160 nM
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| 3 |
EC50 = 161 nM
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| 4 |
EC50 = 710 nM
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| 5 |
Kd = 5 nM
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CP0560085
|
(3S)-3-cyclopropyl-3-[3-[[6-(2,2-dimethylpropyl)-5-(2-fluoro-5-methoxyphenyl)pyridin-2-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C30H34FNO4
|
1
|
| 1 |
EC50 = 150 nM
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CP0443548
|
2-[4-[[3-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]-2-methylphenoxy]acetic acid
Show/Hide
|
C28H32O7S
|
1
|
| 1 |
EC50 = 153.3 nM
|
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CP0536859
|
2-[2-fluoro-4-[[4-methyl-2-(4-methylphenyl)-1,3-thiazol-5-yl]methoxy]phenoxy]acetic acid
Show/Hide
|
C20H18FNO4S
|
1
|
| 1 |
EC50 = 156 nM
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CP0567118
|
2-[6-[[3-(3-methylthiophen-2-yl)phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C22H20O4S
|
1
|
| 1 |
EC50 = 157.1 nM
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CP0445278
|
3-[4-[[2-(3-chlorophenyl)-1,3-oxazol-4-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C19H16ClNO4
|
1
|
| 1 |
EC50 = 160 nM
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CP0555905
|
3-[3-[[1-[2-[(2-cyano-2-methylpropyl)-pyridin-2-ylcarbamoyl]-5-methoxyphenyl]piperidin-4-yl]methoxy]phenyl]-3-cyclopropylpropanoic acid
Show/Hide
|
C36H42N4O5
|
1
|
| 1 |
EC50 = 160 nM
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|
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CP0406221
|
(3S)-3-cyclopropyl-3-[2-[[4-(5-fluoro-2-methoxypyridin-4-yl)-3-[(1R)-1-methoxy-2,2-dimethylpropyl]phenyl]methoxy]pyridin-4-yl]propanoic acid
Show/Hide
|
C30H35FN2O5
|
1
|
| 1 |
EC50 = 162 nM
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CP0547296
|
2-[4-[[3-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
|
C27H30O8S2
|
1
|
| 1 |
EC50 = 169.82 nM
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CP0497892
|
3-{4-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]phenyl}-2-methylpropanoic Acid
Show/Hide
|
C25H26O3
|
1
|
| 1 |
EC50 = 170 nM
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CP0504441
|
3-{4-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]phenyl}-2-fluoropropanoic Acid
Show/Hide
|
C24H23FO3
|
1
|
| 1 |
EC50 = 170 nM
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CP0394482
|
(3R)-3-[3-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]butanoic acid
Show/Hide
|
C31H35FO4
|
1
|
| 1 |
EC50 = 170 nM
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CP0576548
|
2-[2-fluoro-4-[[3-(4-methoxyphenyl)phenyl]methoxy]phenoxy]acetic acid
Show/Hide
|
C22H19FO5
|
1
|
| 1 |
EC50 = 170 nM
|
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CP0432472
|
N,N-dimethyl-3-[4-[(3-phenoxyphenyl)methylamino]phenyl]propanamide
Show/Hide
|
C24H26N2O2
|
1
|
| 1 |
EC50 = 173.78 nM
|
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CP0412843
|
2-[4-[[4-[(2Z)-2-methoxyimino-2-phenylethoxy]phenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
|
C24H23NO7S
|
1
|
| 1 |
EC50 = 177.83 nM
|
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CP0452171
|
3-[4-[(4-methylphenyl)methoxy]phenyl]hex-4-ynoic acid
Show/Hide
|
C20H20O3
|
1
|
| 1 |
EC50 = 180 nM
|
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CP0400562
|
2-[6-[[3-(1-benzothiophen-5-yl)phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C25H20O4S
|
2
|
| 1 |
EC50 = 180 nM
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|
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| 2 |
Ki = 570 nM
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CP0404845
|
(1'R,3R)-5-[[3-(5,5-dimethylcyclopenten-1-yl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]spiro[1,2-dihydroindene-3,2'-cyclopropane]-1'-carboxylic acid
Show/Hide
|
C33H33FO4
|
1
|
| 1 |
EC50 = 180 nM
|
|
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CP0555904
|
3-cyclopropyl-3-[3-[[1-[5-methoxy-2-[methyl(pyridin-2-yl)carbamoyl]phenyl]piperidin-4-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C32H37N3O5
|
1
|
| 1 |
EC50 = 180 nM
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CP0434423
|
2-[2-fluoro-4-[[2-(3-fluorophenyl)-4-methyl-1,3-thiazol-5-yl]methoxy]phenoxy]acetic acid
Show/Hide
|
C19H15F2NO4S
|
1
|
| 1 |
EC50 = 185 nM
|
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CP0409591
|
(3S)-3-ethoxy-3-[4-[(4-methoxy-2,3-dihydro-1H-inden-1-yl)oxy]phenyl]propanoic acid
Show/Hide
|
C21H24O5
|
1
|
| 1 |
EC50 = 190 nM
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CP0443186
|
3-thiophen-2-yl-3-[4-[[3-[4-(trifluoromethyl)phenyl]phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C27H21F3O3S
|
1
|
| 1 |
EC50 = 190 nM
|
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CP0544909
|
3-pyridin-4-yl-3-[4-[[3-[4-(trifluoromethyl)phenyl]phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C28H22F3NO3
|
1
|
| 1 |
EC50 = 190 nM
|
|
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CP0403902
|
2-[(3S,8S)-3-(3,4-dichlorophenyl)-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C18H14Cl2O5
|
1
|
| 1 |
EC50 = 190.5 nM
|
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CP0488071
|
2-[4-[[2-(4-fluorophenyl)-4-methyl-1,3-thiazol-5-yl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
|
C19H16FNO5S2
|
2
|
| 1 |
EC50 = 190.55 nM
|
|
|
| 2 |
EC50 = 253 nM
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CP0477794
|
2-[4-[[3-(2,6-dimethylphenyl)phenyl]methoxy]phenyl]sulfanylacetic acid
Show/Hide
|
C23H22O3S
|
1
|
| 1 |
EC50 = 194.98 nM
|
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CP0547295
|
2-[4-[[3-(2-methoxyphenyl)phenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
|
C22H20O6S
|
1
|
| 1 |
EC50 = 194.98 nM
|
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CP0575248
|
2-[4-[[3-(4-ethoxy-2,6-dimethylphenyl)phenyl]methylamino]phenoxy]acetic acid
Show/Hide
|
C25H27NO4
|
1
|
| 1 |
EC50 = 196.7 nM
|
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CP0401255
|
(1S,2S)-2-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylamino]phenyl]-N-pyrrolidin-3-ylcyclopropane-1-carboxamide
Show/Hide
|
C26H27F3N4OS
|
1
|
| 1 |
EC50 = 204.17 nM
|
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CP0403901
|
2-[(8S)-3-[3-[2-chloro-4-(3-methylsulfonylpropoxy)phenyl]-5-fluorophenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C28H26ClFO8S
|
1
|
| 1 |
EC50 = 205.1 nM
|
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CP0443646
|
3-[4-[[3-(4-ethylphenyl)-1,2,4-oxadiazol-5-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C20H20N2O4
|
1
|
| 1 |
EC50 = 210 nM
|
|
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CP0431850
|
3-[4-[(3,4-dichlorophenyl)methoxy]-3-fluorophenyl]-3-ethoxypropanoic acid
Show/Hide
|
C18H17Cl2FO4
|
1
|
| 1 |
EC50 = 210 nM
|
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CP0393670
|
3-[5-[[3-(2,6-dimethylphenyl)phenyl]methoxy]thiophen-2-yl]hex-4-ynoic acid
Show/Hide
|
C25H24O3S
|
1
|
| 1 |
EC50 = 210 nM
|
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CP0408054
|
3-[5-[[3-(2,6-dimethylphenyl)phenyl]methoxy]thiophen-2-yl]-3-methoxypropanoic acid
Show/Hide
|
C23H24O4S
|
1
|
| 1 |
EC50 = 210 nM
|
|
|
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CP0514108
|
(3R)-3-[5-[[3-(2,2-dimethylcyclopentyl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]-2-fluorophenyl]pentanoic acid
Show/Hide
|
C32H36F2O4
|
1
|
| 1 |
EC50 = 210 nM
|
|
|
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CP0404873
|
(1'R,3R)-5-[[3-[(1S)-2,2-dimethylcyclopentyl]-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]spiro[1,2-dihydroindene-3,2'-cyclopropane]-1'-carboxylic acid
Show/Hide
|
C33H35FO4
|
1
|
| 1 |
EC50 = 212 nM
|
|
|
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CP0415871
|
2-[4-[[4-methyl-2-(3-methylphenyl)-1,3-thiazol-5-yl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
|
C20H19NO5S2
|
1
|
| 1 |
EC50 = 213.8 nM
|
|
|
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CP0538725
|
2-[4-[[4-chloro-3-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
|
C20H18ClNO6S
|
1
|
| 1 |
EC50 = 213.8 nM
|
|
|
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CP0570914
|
3-[4-[[3-[2-(3,5-dimethyl-1,2-oxazol-4-yl)ethynyl]phenyl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
|
C23H20FNO4
|
1
|
| 1 |
EC50 = 214 nM
|
|
|
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CP0403903
|
2-[(3S,8S)-3-(3-chlorophenyl)-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C18H15ClO5
|
1
|
| 1 |
EC50 = 219.8 nM
|
|
|
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CP0576543
|
2-[4-[[3-(5-ethoxy-2-methylphenyl)phenyl]methoxy]-2-fluorophenoxy]acetic acid
Show/Hide
|
C24H23FO5
|
1
|
| 1 |
EC50 = 220 nM
|
|
|
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CP0576086
|
2-[4-[[3-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]methylamino]-2-fluorophenoxy]acetic acid
Show/Hide
|
C20H19FN2O4
|
1
|
| 1 |
EC50 = 225.3 nM
|
|
|
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CP0415645
|
(3S)-3-cyclopropyl-3-[3-[[3-[(2R)-3,3-dimethyloxan-2-yl]-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C33H37FO5
|
1
|
| 1 |
EC50 = 227 nM
|
|
|
|
CP0539921
|
3-ethoxy-3-(6-phenylmethoxypyridin-3-yl)propanoic acid
Show/Hide
|
C17H19NO4
|
1
|
| 1 |
EC50 = 230 nM
|
|
|
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CP0563658
|
(3S)-3-[4-[[3-(spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylmethyl)phenyl]methoxy]phenyl]hex-4-ynoic acid
Show/Hide
|
C33H35NO3
|
1
|
| 1 |
EC50 = 233 nM
|
|
|
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CP0415876
|
2-[5-[[3-(4-methoxy-2,6-dimethylphenyl)phenyl]methoxy]-3-oxo-1,2-dihydroinden-1-yl]acetic acid
Show/Hide
|
C27H26O5
|
1
|
| 1 |
EC50 = 234.42 nM
|
|
|
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CP0545221
|
2-[4-[[2-chloro-5-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
|
C20H18ClNO6S
|
1
|
| 1 |
EC50 = 234.42 nM
|
|
|
|
CP0469486
|
2-[(1R)-6-[[4-(5-fluoro-2-methoxypyridin-4-yl)-3-[(1R)-1-methoxy-2,2-dimethylpropyl]phenyl]methoxy]-1-methyl-2,3-dihydroinden-1-yl]acetic acid
Show/Hide
|
C31H36FNO5
|
1
|
| 1 |
EC50 = 235 nM
|
|
|
|
CP0480377
|
3-{4-[(3'-Methylbiphenyl-3-yl)methoxy]phenyl}propanoic Acid
Show/Hide
|
C23H22O3
|
1
|
| 1 |
EC50 = 240 nM
|
|
|
|
CP0500066
|
3-[4-[(2-phenylphenyl)methoxy]phenyl]hex-4-ynoic acid
Show/Hide
|
C25H22O3
|
1
|
| 1 |
EC50 = 240 nM
|
|
|
|
CP0390301
|
(3S)-3-[4-[[3-(4-chloro-2-methylphenyl)-2-methylphenyl]methoxy]phenyl]-3-(1-methylimidazol-2-yl)propanoic acid
Show/Hide
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C28H27ClN2O3
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2
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| 1 |
EC50 = 240 nM
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| 2 |
EC50 = 23000 nM
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CP0493373
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3-[5-[[3-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]thiophen-2-yl]hex-4-ynoic acid
Show/Hide
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C29H32O6S2
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1
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| 1 |
EC50 = 240 nM
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CP0551921
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2-[2-fluoro-4-[[4-methyl-2-(3-methylphenyl)-1,3-thiazol-5-yl]methoxy]phenoxy]acetic acid
Show/Hide
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C20H18FNO4S
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1
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| 1 |
EC50 = 247 nM
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CP0396876
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(1'R,5R)-3-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(5-fluoro-2-methoxypyridin-4-yl)phenyl]methoxy]spiro[6,7-dihydrocyclopenta[c]pyridine-5,2'-cyclopropane]-1'-carboxylic acid
Show/Hide
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C31H33FN2O4
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1
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| 1 |
EC50 = 249 nM
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CP0396877
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(1'R,5R)-3-[[4-(5-fluoro-2-methoxypyridin-4-yl)-3-[(1R)-1-methoxy-2,2-dimethylpropyl]phenyl]methoxy]spiro[6,7-dihydrocyclopenta[c]pyridine-5,2'-cyclopropane]-1'-carboxylic acid
Show/Hide
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C30H33FN2O5
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1
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| 1 |
EC50 = 250 nM
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CP0565901
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3-cyclopropyl-3-[3-[[1-[2-(4,4-dimethylpentyl)-5-methoxyphenyl]azetidin-3-yl]methoxy]phenyl]propanoic acid
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C30H41NO4
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1
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| 1 |
EC50 = 250 nM
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CP0551919
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2,2-dideuterio-3-[4-[[2-(4-fluorophenyl)-4-methyl-1,3-thiazol-5-yl]methoxy]phenyl]propanoic acid
Show/Hide
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C20H18FNO3S
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1
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| 1 |
EC50 = 251 nM
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CP0429538
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2-[4-[[2-(3-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
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C19H16ClNO5S2
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1
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| 1 |
EC50 = 251.19 nM
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CP0415874
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2-[4-[[3-(2-fluorophenyl)phenyl]methoxy]phenyl]sulfonylacetic acid
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C21H17FO5S
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1
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| 1 |
EC50 = 257.04 nM
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CP0352619
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3-[4-(Biphenyl-3-ylmethoxy)phenyl]propanoic Acid
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C22H20O3
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1
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| 1 |
EC50 = 260 nM
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CP0441390
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3-(4-{[3-(2-Phenylethoxy)benzyl]oxy}phenyl)propanoic Acid
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C24H24O4
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1
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| 1 |
EC50 = 260 nM
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CP0452169
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3-[4-[(4-methoxyphenyl)methoxy]phenyl]hex-4-ynoic acid
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C20H20O4
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1
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| 1 |
EC50 = 260 nM
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CP0476696
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3-[4-[[4-[[4-[2-(6-methylpyridin-2-yl)oxyethyl]-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;dihydrochloride
Show/Hide
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C34H44Cl2N2O5
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1
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| 1 |
EC50 = 260 nM
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CP0576009
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2-[2-fluoro-4-[[3-(5-methoxy-2-methylphenyl)phenyl]methoxy]phenoxy]acetic acid
Show/Hide
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C23H21FO5
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1
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| 1 |
EC50 = 260 nM
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CP0545220
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2-[4-[[3-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
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C20H19NO6S
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1
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| 1 |
EC50 = 269.15 nM
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CP0443706
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2-[(3R)-6-[[3-[2,6-dimethyl-4-[(3-methyloxetan-3-yl)methoxy]phenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
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C30H32O6
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2
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| 1 |
EC50 = 270 nM
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| 2 |
Ki = 270 nM
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CP0425728
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3-cyclopropyl-3-[3-[[1-(5-methoxy-2-methylphenyl)piperidin-4-yl]methoxy]phenyl]propanoic acid
Show/Hide
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C26H33NO4
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1
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| 1 |
EC50 = 270 nM
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CP0545562
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2-[2-fluoro-4-[[3-(6-methoxynaphthalen-2-yl)phenyl]methoxy]phenoxy]acetic acid
Show/Hide
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C26H21FO5
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1
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| 1 |
EC50 = 270 nM
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CP0477800
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2-[4-[[2-(3-fluorophenyl)-4-methyl-1,3-thiazol-5-yl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
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C19H16FNO5S2
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1
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| 1 |
EC50 = 275.42 nM
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CP0400943
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3-[4-[[4-[[4-[(4-methoxyphenyl)methyl]-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;hydrochloride
Show/Hide
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C34H42ClNO5
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1
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| 1 |
EC50 = 280 nM
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CP0396826
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(3R)-3-[2-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(5-fluoro-2-methoxypyridin-4-yl)phenyl]methoxy]pyridin-4-yl]butanoic acid
Show/Hide
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C29H33FN2O4
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1
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| 1 |
EC50 = 281 nM
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CP0500632
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2-[(3S,8S)-3-[3-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
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C30H32O8S
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1
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| 1 |
EC50 = 282 nM
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CP0449547
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2-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylamino]phenoxy]acetic acid
Show/Hide
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C20H17F3N2O3S
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1
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| 1 |
EC50 = 288.4 nM
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CP0529142
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2-[4-[(3-phenylphenyl)methoxy]phenyl]sulfonylacetic acid
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C21H18O5S
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1
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| 1 |
EC50 = 288.4 nM
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CP0461988
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2-[(3R)-6-[[3-[4-(2-ethoxyethoxy)-2,6-dimethylphenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
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C29H32O6
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2
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| 1 |
EC50 = 290 nM
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| 2 |
Ki = 280 nM
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CP0462189
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2-[(3R)-6-[[3-[4-(1,1-dioxothian-4-yl)oxy-2,6-dimethylphenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
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C30H32O7S
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2
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| 1 |
EC50 = 290 nM
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| 2 |
Ki = 300 nM
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CP0378796
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3-[4-(Biphenyl-4-ylmethoxy)phenyl]propanoic Acid
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C22H20O3
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1
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| 1 |
EC50 = 300 nM
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CP0522922
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3-(4-{[3-(Benzyloxy)benzyl]oxy}phenyl)propanoic Acid
Show/Hide
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C23H22O4
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1
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| 1 |
EC50 = 300 nM
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CP0141574
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3-[4-[[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]methoxy]phenyl]propanoic acid
Show/Hide
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C19H18N2O4
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1
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| 1 |
EC50 = 300 nM
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CP0439377
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(1S,2R)-2-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylamino]phenyl]cyclopropane-1-carboxylic acid
Show/Hide
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C22H19F3N2O2S
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1
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| 1 |
EC50 = 302 nM
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CP0404980
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3-{4-[(4-Phenoxybenzyl)oxy]phenyl}propanoic Acid
Show/Hide
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C22H20O4
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1
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| 1 |
EC50 = 310 nM
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CP0513620
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(3S)-3-cyclopropyl-3-[3-[[3-[(1S)-2,2-dimethylcyclopentyl]-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
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C33H37FO4
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1
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| 1 |
EC50 = 310 nM
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CP0504440
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3-{4-[2-(2',6'-Dimethylbiphenyl-3-yl)ethyl]phenyl}propanoic Acid
Show/Hide
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C25H26O2
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1
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| 1 |
EC50 = 320 nM
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CP0459739
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2-[4-[(3-phenoxyphenyl)methylamino]phenyl]sulfanylacetic acid
Show/Hide
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C21H19NO3S
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1
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| 1 |
EC50 = 323.59 nM
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CP0905617
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3-(4-((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methoxy)phenyl)propanoic-2,2-d2 acid
Show/Hide
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C21H18F3NO3S
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1
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| 1 |
EC50 = 325 nM
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CP0488091
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(3R)-3-ethoxy-3-[4-[[(1R)-4-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl]oxy]phenyl]propanoic acid
Show/Hide
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C21H21F3O4
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1
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| 1 |
EC50 = 330 nM
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CP0420573
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3-phenyl-3-[4-[[3-[4-(trifluoromethyl)phenyl]phenyl]methoxy]phenyl]propanoic acid
Show/Hide
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C29H23F3O3
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1
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| 1 |
EC50 = 330 nM
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CP0443187
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3-pyridin-2-yl-3-[4-[[3-[4-(trifluoromethyl)phenyl]phenyl]methoxy]phenyl]propanoic acid
Show/Hide
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C28H22F3NO3
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1
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| 1 |
EC50 = 330 nM
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CP0536857
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2-[4-[(4-methyl-2-phenyl-1,3-thiazol-5-yl)methoxy]phenyl]sulfonylacetic acid
Show/Hide
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C19H17NO5S2
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2
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| 1 |
EC50 = 331.13 nM
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| 2 |
EC50 = 370 nM
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CP0545561
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2-[4-[[3-[5-(cyclopropylmethoxy)-2-methylphenyl]phenyl]methoxy]-2-fluorophenoxy]acetic acid
Show/Hide
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C26H25FO5
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1
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| 1 |
EC50 = 340 nM
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CP0483163
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(1'R,4R)-6-[[3-(5,5-dimethylcyclopenten-1-yl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]spiro[2,3-dihydro-1H-naphthalene-4,2'-cyclobutane]-1'-carboxylic acid
Show/Hide
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C35H37FO4
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1
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| 1 |
EC50 = 350 nM
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CP0419434
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2-methyl-3-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylamino]phenyl]propanoic acid
Show/Hide
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C22H21F3N2O2S
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1
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| 1 |
EC50 = 354.81 nM
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CP0476414
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3-[4-(3-phenylphenoxy)phenyl]hex-4-ynoic acid
Show/Hide
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C24H20O3
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1
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| 1 |
EC50 = 360 nM
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CP0456295
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(3R)-3-[4-[(3,4-dichlorophenyl)methoxy]phenyl]-3-ethoxypropanoic acid
Show/Hide
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C18H18Cl2O4
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1
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| 1 |
EC50 = 360 nM
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CP0550614
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2-[4-[[3-(4-ethoxyphenyl)phenyl]methoxy]-2-fluorophenoxy]acetic acid
Show/Hide
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C23H21FO5
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1
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| 1 |
EC50 = 360 nM
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CP0477798
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2-[4-[[3-(3,5-dimethyl-1,2-oxazol-4-yl)-2-methylphenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
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C21H21NO6S
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1
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| 1 |
EC50 = 363.08 nM
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CP0455253
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(3S)-3-[3-[[3-tert-butyl-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]-3-cyclopropylpropanoic acid
Show/Hide
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C30H33FO4
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2
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| 1 |
EC50 = 370 nM
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| 2 |
EC50 = 1900 nM
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CP0481296
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(3R)-3-[3-[[3-tert-butyl-4-(3-methoxyphenyl)phenyl]methoxy]phenyl]hexanoic acid
Show/Hide
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C30H36O4
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1
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| 1 |
EC50 = 370 nM
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CP0447125
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3-ethoxy-3-[4-[(4-methylphenyl)methoxy]phenyl]propanoic acid
Show/Hide
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C19H22O4
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1
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| 1 |
EC50 = 370 nM
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CP0434420
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2-[2-fluoro-4-[(4-methyl-2-phenyl-1,3-thiazol-5-yl)methoxy]phenoxy]acetic acid
Show/Hide
|
C19H16FNO4S
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1
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| 1 |
EC50 = 374 nM
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CP0574603
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2-[4-[[3-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]phenoxy]propanoic acid
Show/Hide
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C28H32O7S
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1
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| 1 |
EC50 = 389.3 nM
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CP0570261
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2-[4-[[3-(6-ethoxynaphthalen-2-yl)phenyl]methoxy]-2-fluorophenoxy]acetic acid
Show/Hide
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C27H23FO5
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1
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| 1 |
EC50 = 390 nM
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CP0571242
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2-[2-fluoro-4-[[3-[2-methyl-5-(2-phenylethoxy)phenyl]phenyl]methoxy]phenoxy]acetic acid
Show/Hide
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C30H27FO5
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1
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| 1 |
EC50 = 390 nM
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CP0438001
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3-(4-isoquinolin-1-yloxyphenyl)hex-4-ynoic acid
Show/Hide
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C21H17NO3
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2
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| 1 |
EC50 = 394 nM
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| 2 |
IC50 = 342 nM
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CP0477505
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2-[2-fluoro-4-[[4-[(2Z)-2-methoxyimino-2-phenylethoxy]phenyl]methylamino]phenoxy]acetic acid
Show/Hide
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C24H23FN2O5
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1
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| 1 |
EC50 = 397.5 nM
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CP0472634
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3-pyridin-3-yl-3-[4-[[3-[4-(trifluoromethyl)phenyl]phenyl]methoxy]phenyl]propanoic acid
Show/Hide
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C28H22F3NO3
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1
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| 1 |
EC50 = 400 nM
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CP0579905
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2-[2-fluoro-4-[[3-(4-methoxyphenyl)phenoxy]methyl]phenoxy]acetic acid
Show/Hide
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C22H19FO5
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1
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| 1 |
EC50 = 400 nM
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CP0420548
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(3S)-3-[4-[[3-(2-methoxyphenyl)phenyl]methoxy]phenyl]-3-(1-methylimidazol-2-yl)propanoic acid
Show/Hide
|
C27H26N2O4
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1
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| 1 |
EC50 = 410 nM
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CP0455532
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3-[4-[[4-[[4-[(4-fluorophenyl)methyl]-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;hydrochloride
Show/Hide
|
C33H39ClFNO4
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1
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| 1 |
EC50 = 410 nM
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CP0393674
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(3S)-3-[5-[[3-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]thiophen-2-yl]hex-4-ynoic acid
Show/Hide
|
C29H32O6S2
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1
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| 1 |
EC50 = 410 nM
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CP0560084
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3-cyclopropyl-3-[3-[[4-[2-(4,4-dimethylpentyl)-5-methoxyphenyl]phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C33H40O4
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1
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| 1 |
EC50 = 410 nM
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CP0395973
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(3S)-3-[3-[[3-tert-butyl-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]-3-cyclobutylpropanoic acid
Show/Hide
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C31H35FO4
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1
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| 1 |
EC50 = 420 nM
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CP0420294
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3-[6-[[3-(2,6-dimethylphenyl)phenyl]methoxy]pyridazin-3-yl]propanoic acid
Show/Hide
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C22H22N2O3
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1
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| 1 |
EC50 = 420 nM
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CP0415878
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2-[4-[[5-(3,5-dimethyl-1,2-oxazol-4-yl)-2-methylphenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
|
C21H21NO6S
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1
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| 1 |
EC50 = 426.58 nM
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CP0377589
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(3S)-3-[4-[[3-(4-methoxyphenyl)phenyl]methoxy]phenyl]-3-(1-methylimidazol-2-yl)propanoic acid
Show/Hide
|
C27H26N2O4
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1
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| 1 |
EC50 = 440 nM
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CP0482616
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3-[2-(2-methylphenyl)-1H-indol-5-yl]propanoic acid
Show/Hide
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C18H17NO2
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1
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| 1 |
EC50 = 447 nM
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CP0548518
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3-[5-[[3-[2,6-dimethyl-4-[(3-methyloxetan-3-yl)methoxy]phenyl]phenyl]methoxy]thiophen-2-yl]hex-4-ynoic acid
Show/Hide
|
C30H32O5S
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1
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| 1 |
EC50 = 450 nM
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CP0392461
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3-[3-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C30H33FO4
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1
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| 1 |
EC50 = 450 nM
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CP0568313
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2-[4-[[3-(1-benzofuran-6-yl)phenyl]methoxy]-2-fluorophenoxy]acetic acid
Show/Hide
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C23H17FO5
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1
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| 1 |
EC50 = 450 nM
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CP0415869
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2-[4-[[3-(2-cyanophenyl)phenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
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C22H17NO5S
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1
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| 1 |
EC50 = 457.09 nM
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CP0891894
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5-(4-(4-fluorophenoxy)benzyl)thiazolidine-2,4-dione
Show/Hide
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C16H12FNO3S
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2
|
| 1 |
EC50 = 474 nM
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| 2 |
EC50 = 500 nM
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CP0393322
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(3S)-3-cyclopropyl-3-[3-[[4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C26H25FO4
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2
|
| 1 |
EC50 = 480 nM
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| 2 |
EC50 = 38000 nM
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CP0569185
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2-[4-[[3-(3-ethoxyphenyl)phenyl]methoxy]-2-fluorophenoxy]acetic acid
Show/Hide
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C23H21FO5
|
1
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| 1 |
EC50 = 480 nM
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CP0576544
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2-[4-[[3-[6-(cyclopropylmethoxy)naphthalen-2-yl]phenyl]methoxy]-2-fluorophenoxy]acetic acid
Show/Hide
|
C29H25FO5
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1
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| 1 |
EC50 = 480 nM
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CP0568241
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2-[4-[[3-[5-(cyclopentylmethoxy)-2-methylphenyl]phenyl]methoxy]-2-fluorophenoxy]acetic acid
Show/Hide
|
C28H29FO5
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1
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| 1 |
EC50 = 490 nM
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CP0500642
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2-[(1R)-6-[[3-(5,5-dimethylcyclopenten-1-yl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Show/Hide
|
C32H33FO4
|
1
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| 1 |
EC50 = 500 nM
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CP0425297
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3-[4-[1-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]ethoxy]phenyl]propanoic acid
Show/Hide
|
C19H17ClN2O4
|
1
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| 1 |
EC50 = 500 nM
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CP0407453
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3-[4-[[6-(3,5-dimethyl-1,2-oxazol-4-yl)pyridin-2-yl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
|
C20H19FN2O4
|
1
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| 1 |
EC50 = 506 nM
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CP0424816
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Benzyloxyphenylpropanoic acid
Show/Hide
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C16H16O3
|
1
|
| 1 |
EC50 = 510 nM
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CP0476019
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2-[6-[[3-[4-(2-ethoxyethoxy)-2,6-dimethylphenyl]phenyl]methoxy]-1,2,3,4-tetrahydronaphthalen-2-yl]acetic acid
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C31H36O5
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2
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| 1 |
EC50 = 510 nM
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| 2 |
Ki = 2100 nM
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CP0543691
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3-{4-[[(2',6'-Dimethylbiphenyl-3-yl)methyl](methyl)amino]-phenyl}propanoic Acid
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C25H27NO2
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1
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| 1 |
EC50 = 520 nM
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CP0499691
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(1'R,3S)-5-[[3-(5,5-dimethylcyclopenten-1-yl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]spiro[1,2-dihydroindene-3,2'-cyclobutane]-1'-carboxylic acid
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C34H35FO4
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1
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| 1 |
EC50 = 520 nM
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CP0568918
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2-[4-[[3-[5-(2-cyclohexylethoxy)-2-methylphenyl]phenyl]methoxy]-2-fluorophenoxy]acetic acid
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C30H33FO5
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1
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| 1 |
EC50 = 520 nM
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CP0479890
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3-(4-{[3-(Thiophen-2-yl)benzyl]oxy}phenyl)propanoic Acid
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C20H18O3S
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1
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| 1 |
EC50 = 530 nM
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CP0575062
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2-[2-fluoro-4-[[3-(2-methoxyphenyl)phenyl]methylamino]phenoxy]acetic acid
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C22H20FNO4
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1
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| 1 |
EC50 = 536.2 nM
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CP0389855
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2-[2-[[3-(2,6-dimethylphenyl)phenyl]methoxy]-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-yl]acetic acid
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C28H30O3
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3
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| 1 |
EC50 = 540 nM
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| 2 |
EC50 = 940 nM
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| 3 |
Ki = 2400 nM
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CP0078179
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3-[4-[[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]methoxy]phenyl]propanoic acid
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C18H15ClN2O4
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1
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| 1 |
EC50 = 540 nM
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CP0576542
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2-[4-[[3-[4-(cyclopropylmethoxy)phenyl]phenyl]methoxy]-2-fluorophenoxy]acetic acid
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C25H23FO5
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1
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| 1 |
EC50 = 540 nM
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CP0577018
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2-[2-fluoro-4-[[3-(3-methoxyphenyl)phenyl]methoxy]phenoxy]acetic acid
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C22H19FO5
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1
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| 1 |
EC50 = 540 nM
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CP0415875
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2-[3-hydroxy-5-[[3-(4-methoxy-2,6-dimethylphenyl)phenyl]methoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
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C27H28O5
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1
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| 1 |
EC50 = 549.54 nM
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CP0477792
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2-[4-[[2-(2-fluorophenyl)-4-methyl-1,3-thiazol-5-yl]methoxy]phenyl]sulfonylacetic acid
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C19H16FNO5S2
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1
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| 1 |
EC50 = 549.54 nM
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CP0392254
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3-[4-[[2-(3-fluorophenyl)-1,3-oxazol-4-yl]methoxy]phenyl]propanoic acid
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C19H16FNO4
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1
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| 1 |
EC50 = 560 nM
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CP0409595
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3-[4-(4-chloronaphthalen-1-yl)oxyphenyl]-3-ethoxypropanoic acid
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C21H19ClO4
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1
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| 1 |
EC50 = 560 nM
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CP0520206
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(1R,2R)-2-[4-[(3-phenoxyphenyl)methylamino]phenyl]cyclopropane-1-carboxylic acid
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C23H21NO3
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1
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| 1 |
EC50 = 562.34 nM
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CP0476017
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2-[2-[[3-(2,6-dimethylphenyl)phenyl]methoxy]-6,7-dihydro-5H-cyclopenta[b]pyridin-5-yl]acetic acid
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C25H25NO3
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2
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| 1 |
EC50 = 570 nM
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| 2 |
Ki > 10000 nM
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CP0392994
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3-(4-fluorophenyl)-3-[4-[(4-methoxyphenyl)methoxy]phenyl]propanoic acid
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C23H21FO4
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1
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| 1 |
EC50 = 580 nM
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CP0409600
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3-ethoxy-3-[4-[(2-methylphenyl)methoxy]phenyl]-N-methylsulfonylpropanamide
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C20H25NO5S
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1
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| 1 |
EC50 = 580 nM
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CP0191122
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3-[4-[[5-[(2-fluorophenyl)carbamoyl]-1,3,4-thiadiazol-2-yl]methoxy]phenyl]propanoic acid
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C19H16FN3O4S
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1
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| 1 |
EC50 = 580 nM
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CP0452086
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3-[4-[[5-[(3,4-difluorophenyl)carbamoyl]-1,3,4-thiadiazol-2-yl]methoxy]phenyl]propanoic acid
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C19H15F2N3O4S
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1
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| 1 |
EC50 = 580 nM
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CP0564249
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3-[5-[[3-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]thiophen-2-yl]propanoic acid
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C21H19FO4S
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1
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| 1 |
EC50 = 580 nM
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CP0434422
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2,2-dideuterio-3-[4-[(4-methyl-2-phenyl-1,3-thiazol-5-yl)methoxy]phenyl]propanoic acid
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C20H19NO3S
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1
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| 1 |
EC50 = 590 nM
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CP0450264
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3-[4-[[3-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]methoxy]phenyl]propanoic acid
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C19H15F3N2O4
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1
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| 1 |
EC50 = 610 nM
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CP0545560
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2-[2-fluoro-4-[[3-(2-methyl-5-propoxyphenyl)phenyl]methoxy]phenoxy]acetic acid
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C25H25FO5
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1
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| 1 |
EC50 = 610 nM
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CP0439982
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3-(4-phenylmethoxyphenyl)hex-4-ynoic acid
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C19H18O3
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1
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| 1 |
EC50 = 620 nM
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CP0420399
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3-[5-[2-[2-(cyanomethyl)phenyl]ethynyl]thiophen-2-yl]propanoic acid
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C17H13NO2S
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1
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| 1 |
EC50 = 640 nM
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CP0395972
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(3S)-3-[4-[[4-(3-methoxyphenyl)phenyl]methoxy]phenyl]hex-4-ynoic acid
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C26H24O4
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1
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| 1 |
EC50 = 650 nM
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CP0565882
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3-cyclopropyl-3-[3-[[1-(2-fluoro-5-methoxyphenyl)piperidin-4-yl]methoxy]phenyl]propanoic acid
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C25H30FNO4
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1
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| 1 |
EC50 = 670 nM
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CP0578510
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2-[4-[[3-[3-(cyclopropylmethoxy)phenyl]phenyl]methoxy]-2-fluorophenoxy]acetic acid
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C25H23FO5
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1
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| 1 |
EC50 = 670 nM
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CP0453383
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(3R)-3-[3-[[3-tert-butyl-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]pentanoic acid
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C29H33FO4
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1
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| 1 |
EC50 = 680 nM
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CP0425292
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3-[4-[[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]methoxy]phenyl]propanoic acid
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C18H15FN2O4
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1
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| 1 |
EC50 = 680 nM
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CP0465448
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3-(4-(2-chloro-4-(trifluoromethyl)phenoxy)phenyl)propanoic acid
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C16H12ClF3O3
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1
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| 1 |
EC50 = 686 nM
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CP0498320
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(3R)-3-[3-[[3-tert-butyl-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]hexanoic acid
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C30H35FO4
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1
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| 1 |
EC50 = 690 nM
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CP0403434
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(3S)-3-[4-[[3-(2-cyanophenyl)phenyl]methoxy]phenyl]-3-(1-methylimidazol-2-yl)propanoic acid
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C27H23N3O3
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1
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| 1 |
EC50 = 690 nM
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CP0425293
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3-[4-[(2-phenyl-1,3-oxazol-4-yl)methoxy]phenyl]propanoic acid
Show/Hide
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C19H17NO4
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1
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| 1 |
EC50 = 700 nM
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CP0432013
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2-[4-[[3-(2-cyanophenyl)phenyl]methylamino]-2-fluorophenoxy]acetic acid
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C22H17FN2O3
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1
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| 1 |
EC50 = 728.6 nM
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CP0392460
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(3R)-3-[3-[[3-(5,5-dimethylcyclopenten-1-yl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]-4-fluorophenyl]pentanoic acid
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C32H34F2O4
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1
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| 1 |
EC50 = 740 nM
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CP0406239
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(3S)-3-[4-[[3-(3-methoxyphenyl)phenyl]methoxy]phenyl]-3-(1-methylimidazol-2-yl)propanoic acid
Show/Hide
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C27H26N2O4
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1
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| 1 |
EC50 = 750 nM
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CP0065854
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3-[5-[[3-(3-methylphenyl)phenyl]carbamoyl]-1,3,4-thiadiazol-2-yl]propanoic acid
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C19H17N3O3S
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1
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| 1 |
EC50 = 760 nM
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CP0393320
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(3R)-3-[3-[[3-tert-butyl-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]butanoic acid
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C28H31FO4
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1
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| 1 |
EC50 = 770 nM
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CP0545489
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3-[2-(4-chlorophenyl)-1H-indol-5-yl]propanoic acid
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C17H14ClNO2
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1
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| 1 |
EC50 = 778 nM
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CP0465262
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3-[3-[[3-(5,5-dimethylcyclopenten-1-yl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
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C30H31FO4
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1
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| 1 |
EC50 = 790 nM
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CP0400942
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3-[4-[[4-[[4-[(2-fluorophenyl)methyl]-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;hydrochloride
Show/Hide
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C33H39ClFNO4
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1
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| 1 |
EC50 = 810 nM
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CP0458233
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(1'R,8S)-3-[[3-(5,5-dimethylcyclopenten-1-yl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]spiro[bicyclo[4.2.0]octa-1(6),2,4-triene-8,2'-cyclopropane]-1'-carboxylic acid
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C32H31FO4
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1
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| 1 |
EC50 = 820 nM
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CP0466396
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2-[3-[3-[[1-[2-[2,2-dimethylpropyl-(6-methylpyridin-2-yl)carbamoyl]-5-methoxyphenyl]piperidin-4-yl]methoxy]phenyl]oxetan-3-yl]acetic acid
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C36H45N3O6
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1
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| 1 |
EC50 = 840 nM
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CP0570913
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3-[4-[[2-(3,5-dimethyl-1,2-oxazol-4-yl)pyridin-4-yl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
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C20H19FN2O4
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1
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| 1 |
EC50 = 862 nM
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CP0570262
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2-[2-fluoro-4-[[3-(2-methyl-5-phenylmethoxyphenyl)phenyl]methoxy]phenoxy]acetic acid
Show/Hide
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C29H25FO5
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1
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| 1 |
EC50 = 870 nM
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CP0568240
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2-[4-[[3-(1-benzothiophen-6-yl)phenyl]methoxy]-2-fluorophenoxy]acetic acid
Show/Hide
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C23H17FO4S
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1
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| 1 |
EC50 = 880 nM
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CP0431606
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3-[4-[(4-methoxyphenyl)methoxy]phenyl]pent-4-enoic acid
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C19H20O4
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1
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| 1 |
EC50 = 900 nM
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CP0393321
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3-[3-[[3-tert-butyl-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
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C27H29FO4
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1
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| 1 |
EC50 = 900 nM
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CP0558830
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3-[4-[[4-[(4-pyridin-2-yloxy-1-oxa-9-azaspiro[5.5]undecan-9-yl)methyl]phenyl]methoxy]phenyl]propanoic acid
Show/Hide
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C31H36N2O5
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1
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| 1 |
EC50 = 900 nM
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CP0571303
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2-[4-[[3-[5-(cyclohexylmethoxy)-2-methylphenyl]phenyl]methoxy]-2-fluorophenoxy]acetic acid
Show/Hide
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C29H31FO5
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1
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| 1 |
EC50 = 910 nM
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CP0917221
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rac-5-(1-(4-(benzyloxy)phenyl)but-2-ynyl)oxazolidine-2,4-dione
Show/Hide
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C20H17NO4
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2
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| 1 |
EC50 = 954 nM
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| 2 |
IC50 = 4399 nM
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CP0389833
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5-[[3-[4-(2-ethoxyethoxy)-2,6-dimethylphenyl]phenyl]methoxy]-2,3-dihydro-1H-indene-2-carboxylic acid
Show/Hide
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C29H32O5
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2
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| 1 |
EC50 = 960 nM
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| 2 |
Ki > 10000 nM
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CP0503183
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2-(4-(2-chloro-4-(trifluoromethyl)phenoxy)benzyl)malonic acid
Show/Hide
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C17H12ClF3O5
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1
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| 1 |
EC50 = 970 nM
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CP0431846
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3-[4-[(3,4-dichlorophenyl)methoxy]-2-methoxyphenyl]-3-ethoxypropanoic acid
Show/Hide
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C19H20Cl2O5
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1
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| 1 |
EC50 = 970 nM
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CP0560086
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3-cyclopropyl-3-[3-[[1-[2-(3-hydroxy-3-methylbutyl)-5-methoxyphenyl]piperidin-4-yl]methoxy]phenyl]propanoic acid
Show/Hide
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C30H41NO5
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1
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| 1 |
EC50 = 970 nM
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CP0425729
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3-cyclopropyl-3-[3-[[1-[5-methoxy-2-[[methyl(2-methylpropyl)amino]methyl]phenyl]piperidin-4-yl]methoxy]phenyl]propanoic acid
Show/Hide
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C31H44N2O4
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1
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| 1 |
EC50 = 1000 nM
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CP0459096
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3-[2-[2-(trifluoromethoxy)phenyl]-1H-indol-5-yl]propanoic acid
Show/Hide
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C18H14F3NO3
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1
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| 1 |
EC50 = 1016 nM
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CP0429673
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3-[4-[[5-[2-(2-fluorophenyl)-2-phenylethyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenyl]propanoic acid
Show/Hide
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C26H22FN3O3S
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1
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| 1 |
EC50 = 1020 nM
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CP0401117
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3-[4-[[5-(phenylcarbamoyl)-1,3,4-thiadiazol-2-yl]methoxy]phenyl]propanoic acid
Show/Hide
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C19H17N3O4S
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1
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| 1 |
EC50 = 1060 nM
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CP0472627
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3-[4-[[5-(3-fluorophenyl)-1,3-oxazol-2-yl]methoxy]phenyl]propanoic acid
Show/Hide
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C19H16FNO4
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1
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| 1 |
EC50 = 1070 nM
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CP0543690
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3-{4-[(2-Phenoxybenzyl)oxy]phenyl}propanoic Acid
Show/Hide
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C22H20O4
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1
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| 1 |
EC50 = 1100 nM
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CP0461859
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3-[4-[(4-methoxyphenyl)methoxy]phenyl]propanoic acid
Show/Hide
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C17H18O4
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1
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| 1 |
EC50 = 1100 nM
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CP0378071
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(3R)-3-cyclopropyl-3-[3-[[3-(5,5-dimethylcyclopenten-1-yl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
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C33H35FO4
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2
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| 1 |
EC50 = 1100 nM
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| 2 |
EC50 = 34000 nM
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CP0432433
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3-[4-[[3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]methoxy]phenyl]propanoic acid
Show/Hide
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C19H15F3N2O4
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1
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| 1 |
EC50 = 1110 nM
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CP0410167
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3-[4-[[4-[[4-[2-(4-methylpyridin-2-yl)oxyethyl]-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;dihydrochloride
Show/Hide
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C34H44Cl2N2O5
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1
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| 1 |
EC50 = 1110 nM
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CP0456852
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4-(4-{[(3-phenoxyphenyl)methyl]amino}phenyl)butanoic acid
Show/Hide
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C23H23NO3
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1
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| 1 |
EC50 = 1122.02 nM
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CP0450263
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3-[4-[(3-phenyl-1,2,4-oxadiazol-5-yl)methoxy]phenyl]propanoic acid
Show/Hide
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C18H16N2O4
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1
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| 1 |
EC50 = 1130 nM
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CP0549562
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3-[4-[[5-[(3,4-dimethylphenoxy)methyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenyl]propanoic acid
Show/Hide
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C21H21N3O4S
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1
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| 1 |
EC50 = 1130 nM
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CP0481382
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3-[4-[[4-[[4-[2-(3,6-dimethylpyrazin-2-yl)oxyethyl]-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;dihydrochloride
Show/Hide
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C34H45Cl2N3O5
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1
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| 1 |
EC50 = 1140 nM
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CP0431886
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3-[4-[[4-[(4-phenylmethoxy-1-oxa-9-azaspiro[5.5]undecan-9-yl)methyl]phenyl]methoxy]phenyl]propanoic acid;hydrochloride
Show/Hide
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C33H40ClNO5
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1
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| 1 |
EC50 = 1160 nM
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CP0410975
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3-[4-[[5-[(4-ethylphenoxy)methyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenyl]propanoic acid
Show/Hide
|
C21H21N3O4S
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1
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| 1 |
EC50 = 1170 nM
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CP0498059
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3-[4-[[5-[(3-fluorophenyl)carbamoyl]-1,3,4-thiadiazol-2-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C19H16FN3O4S
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1
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| 1 |
EC50 = 1190 nM
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CP0395971
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3-[4-[(4-phenylphenyl)methoxy]phenyl]hex-4-ynoic acid
Show/Hide
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C25H22O3
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2
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| 1 |
EC50 = 1200 nM
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| 2 |
EC50 = 7700 nM
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CP0499548
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3-[4-[(4-methoxyphenyl)methoxy]phenyl]-4-methylpent-3-enoic acid
Show/Hide
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C20H22O4
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1
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| 1 |
EC50 = 1200 nM
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CP0435692
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3-[3-[[4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
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C23H21FO4
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1
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| 1 |
EC50 = 1200 nM
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CP0435693
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(3S)-3-[3-[[3-tert-butyl-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]-3-phenylpropanoic acid
Show/Hide
|
C33H33FO4
|
1
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| 1 |
EC50 = 1200 nM
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CP0425296
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3-[4-[[3-(2-chlorophenyl)-1,2,4-oxadiazol-5-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C18H15ClN2O4
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1
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| 1 |
EC50 = 1200 nM
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CP0566675
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3-[2-(2-fluorophenyl)-1H-indol-5-yl]propanoic acid
Show/Hide
|
C17H14FNO2
|
1
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| 1 |
EC50 = 1207 nM
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|
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CP0526183
|
3-[4-[[4-[[4-[2-[(2-cyclopropyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)oxy]ethyl]-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;dihydrochloride
Show/Hide
|
C38H49Cl2N3O5
|
1
|
| 1 |
EC50 = 1210 nM
|
|
|
|
CP0392247
|
3-[4-[[3-(3-bromophenyl)-1,2,4-oxadiazol-5-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C18H15BrN2O4
|
1
|
| 1 |
EC50 = 1260 nM
|
|
|
|
CP0464079
|
3-[4-[[4-[[4-[2-(6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yloxy)ethyl]-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;dihydrochloride
Show/Hide
|
C35H45Cl2N3O5
|
1
|
| 1 |
EC50 = 1260 nM
|
|
|
|
CP0455533
|
3-[4-[[4-[[4-[[4-(trifluoromethyl)phenyl]methyl]-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;hydrochloride
Show/Hide
|
C34H39ClF3NO4
|
1
|
| 1 |
EC50 = 1270 nM
|
|
|
|
CP0534791
|
3-[4-[[4-[[4-[2-(3-methylpyrazin-2-yl)oxyethyl]-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;dihydrochloride
Show/Hide
|
C33H43Cl2N3O5
|
1
|
| 1 |
EC50 = 1270 nM
|
|
|
|
CP0054882
|
3-[5-[[3-(4-fluorophenyl)phenyl]carbamoyl]-1,3,4-thiadiazol-2-yl]propanoic acid
Show/Hide
|
C18H14FN3O3S
|
1
|
| 1 |
EC50 = 1280 nM
|
|
|
|
CP0567195
|
3-[4-[[4-[[4-[(3-fluorophenyl)methoxy]-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;hydrochloride
Show/Hide
|
C33H39ClFNO5
|
1
|
| 1 |
EC50 = 1300 nM
|
|
|
|
CP0533316
|
3-[2-[2-(trifluoromethyl)phenyl]-1H-indol-5-yl]propanoic acid
Show/Hide
|
C18H14F3NO2
|
1
|
| 1 |
EC50 = 1308 nM
|
|
|
|
CP0498187
|
(3S)-3-[3-[[3-tert-butyl-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]-3-cyclopentylpropanoic acid
Show/Hide
|
C32H37FO4
|
1
|
| 1 |
EC50 = 1310 nM
|
|
|
|
CP0429677
|
3-[4-[[5-[2-(4-methoxyphenyl)-2-phenylethyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenyl]propanoic acid
Show/Hide
|
C27H25N3O4S
|
1
|
| 1 |
EC50 = 1350 nM
|
|
|
|
CP0551920
|
2-[2-fluoro-4-[(4-methyl-2-phenyl-1,3-oxazol-5-yl)methoxy]phenoxy]acetic acid
Show/Hide
|
C19H16FNO5
|
1
|
| 1 |
EC50 = 1350 nM
|
|
|
|
CP0555189
|
3-(4-(2,4-dichlorophenoxy)phenyl)propanoic acid
Show/Hide
|
C15H12Cl2O3
|
1
|
| 1 |
EC50 = 1358 nM
|
|
|
|
CP0559152
|
(1R,2R)-2-[3-[[3-(5,5-dimethylcyclopenten-1-yl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]cyclopropane-1-carboxylic acid
Show/Hide
|
C31H31FO4
|
1
|
| 1 |
EC50 = 1380 nM
|
|
|
|
CP0538706
|
3-[4-[[5-(2,3-dihydro-1H-inden-5-yloxymethyl)-1,3,4-thiadiazole-2-carbonyl]amino]phenyl]propanoic acid
Show/Hide
|
C22H21N3O4S
|
1
|
| 1 |
EC50 = 1380 nM
|
|
|
|
CP0494362
|
3-[4-[4-(trifluoromethyl)naphthalen-1-yl]oxyphenyl]hex-4-ynoic acid
Show/Hide
|
C23H17F3O3
|
2
|
| 1 |
EC50 = 1401 nM
|
|
|
| 2 |
IC50 = 211 nM
|
|
|
|
CP0492858
|
(3S)-3-cyclopropyl-3-[3-[[4-(2-fluoro-5-methoxyphenyl)-3-[(1S)-1-methoxy-2,2-dimethylpropyl]phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C32H37FO5
|
1
|
| 1 |
EC50 = 1410 nM
|
|
|
|
CP0380429
|
(1S,1aS,6aR)-3-[[3-(5,5-dimethylcyclopenten-1-yl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]-1,1a,6,6a-tetrahydrocyclopropa[a]indene-1-carboxylic acid
Show/Hide
|
C32H31FO4
|
1
|
| 1 |
EC50 = 1420 nM
|
|
|
|
CP0577000
|
2-[2-fluoro-4-[[3-[2-methyl-5-(2-methylpropoxy)phenyl]phenyl]methoxy]phenoxy]acetic acid
Show/Hide
|
C26H27FO5
|
1
|
| 1 |
EC50 = 1450 nM
|
|
|
|
CP0550699
|
3-[4-[[4-[[4-(2-pyrazin-2-yloxyethyl)-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;dihydrochloride
Show/Hide
|
C32H41Cl2N3O5
|
1
|
| 1 |
EC50 = 1480 nM
|
|
|
|
CP0431849
|
3-[4-[(3,4-dichlorophenyl)methoxy]-3-methylphenyl]-3-ethoxypropanoic acid
Show/Hide
|
C19H20Cl2O4
|
1
|
| 1 |
EC50 = 1500 nM
|
|
|
|
CP0569335
|
2-[2-fluoro-4-[[3-methoxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]phenoxy]methyl]phenoxy]acetic acid
Show/Hide
|
C25H23FO6
|
1
|
| 1 |
EC50 = 1500 nM
|
|
|
|
CP0498060
|
3-[4-[[5-[(2-methylphenyl)carbamoyl]-1,3,4-thiadiazol-2-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C20H19N3O4S
|
1
|
| 1 |
EC50 = 1520 nM
|
|
|
|
CP0415823
|
3-[4-[[5-[(2-methylphenoxy)methyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenyl]propanoic acid
Show/Hide
|
C20H19N3O4S
|
1
|
| 1 |
EC50 = 1520 nM
|
|
|
|
CP0415822
|
3-[4-[[5-[(2,5-dimethylphenoxy)methyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenyl]propanoic acid
Show/Hide
|
C21H21N3O4S
|
1
|
| 1 |
EC50 = 1530 nM
|
|
|
|
CP0572840
|
2-[4-[[3-[5-(cyclobutylmethoxy)-2-methylphenyl]phenyl]methoxy]-2-fluorophenoxy]acetic acid
Show/Hide
|
C27H27FO5
|
1
|
| 1 |
EC50 = 1530 nM
|
|
|
|
CP0425833
|
3-[4-(5-bromopyrimidin-2-yl)oxyphenyl]hex-4-ynoic acid
Show/Hide
|
C16H13BrN2O3
|
2
|
| 1 |
EC50 = 1568 nM
|
|
|
| 2 |
IC50 = 433 nM
|
|
|
|
CP0429675
|
3-[4-[[5-[(3-chlorophenoxy)methyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenyl]propanoic acid
Show/Hide
|
C19H16ClN3O4S
|
1
|
| 1 |
EC50 = 1570 nM
|
|
|
|
CP0465447
|
3-[4-(3-cyanopyrazin-2-yl)oxyphenyl]hex-4-ynoic acid
Show/Hide
|
C17H13N3O3
|
2
|
| 1 |
EC50 = 1578 nM
|
|
|
| 2 |
IC50 = 2487 nM
|
|
|
|
CP0432434
|
3-[4-[(5-phenyl-1,3-oxazol-2-yl)methoxy]phenyl]propanoic acid
Show/Hide
|
C19H17NO4
|
1
|
| 1 |
EC50 = 1600 nM
|
|
|
|
CP0404210
|
3-ethoxy-3-[4-[(2-methylbenzoyl)amino]phenyl]propanoic acid
Show/Hide
|
C19H21NO4
|
1
|
| 1 |
EC50 = 1600 nM
|
|
|
|
CP0544742
|
3-[5-[[3-(furan-2-yl)phenyl]carbamoyl]-1,3,4-thiadiazol-2-yl]propanoic acid
Show/Hide
|
C16H13N3O4S
|
1
|
| 1 |
EC50 = 1640 nM
|
|
|
|
CP0475703
|
3-[5-[[3-(3-chlorophenyl)phenyl]carbamoyl]-1,3,4-thiadiazol-2-yl]propanoic acid
Show/Hide
|
C18H14ClN3O3S
|
1
|
| 1 |
EC50 = 1690 nM
|
|
|
|
CP0505589
|
3-(4-(4-phenylbutoxy)phenyl)propanoic acid
Show/Hide
|
C19H22O3
|
1
|
| 1 |
EC50 = 1700 nM
|
|
|
|
CP0408762
|
2-[6-[[3-(2,6-dimethylphenyl)phenyl]methoxy]-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C25H22O4
|
3
|
| 1 |
EC50 = 1700 nM
|
|
|
| 2 |
EC50 = 4900 nM
|
|
|
| 3 |
Ki > 10000 nM
|
|
|
|
CP0392415
|
5-[2-ethoxy-2-[4-[(2-methylphenyl)methoxy]phenyl]ethyl]-2H-tetrazole
Show/Hide
|
C19H22N4O2
|
1
|
| 1 |
EC50 = 1700 nM
|
|
|
|
CP0488960
|
3-[4-[[5-[(3-methylphenyl)carbamoyl]-1,3,4-thiadiazol-2-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C20H19N3O4S
|
1
|
| 1 |
EC50 = 1770 nM
|
|
|
|
CP0378802
|
3-(4-{[(2',6'-Dimethylbiphenyl-3-yl)methyl]sulfanyl}phenyl)-propanoic Acid
Show/Hide
|
C24H24O2S
|
1
|
| 1 |
EC50 = 1800 nM
|
|
|
|
CP0402724
|
3-[2-(3-bromophenyl)-1H-indol-5-yl]propanoic acid
Show/Hide
|
C17H14BrNO2
|
1
|
| 1 |
EC50 = 1800 nM
|
|
|
|
CP0478876
|
3-[2-(2-ethylphenyl)-1H-indol-5-yl]propanoic acid
Show/Hide
|
C19H19NO2
|
1
|
| 1 |
EC50 = 1800 nM
|
|
|
|
CP0550557
|
8-[3-methoxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]phenoxy]octanoic acid
Show/Hide
|
C24H30O5
|
1
|
| 1 |
EC50 = 1800 nM
|
|
|
|
CP0409168
|
(3R)-3-cyclopropyl-3-[3-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C33H37FO4
|
1
|
| 1 |
EC50 = 1830 nM
|
|
|
|
CP0452573
|
3-[4-[[4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C23H21FO4
|
1
|
| 1 |
EC50 = 1900 nM
|
|
|
|
CP0407488
|
3-[4-[[4-(3,5-dimethyl-1,2-oxazol-4-yl)pyridin-2-yl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
|
C20H19FN2O4
|
1
|
| 1 |
EC50 = 1930 nM
|
|
|
|
CP0409167
|
(3S)-3-[3-[[3-[(1R)-2,2-dimethylcyclopentyl]-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]pentanoic acid
Show/Hide
|
C32H37FO4
|
1
|
| 1 |
EC50 = 1960 nM
|
|
|
|
CP0388930
|
3-[4-[[4-[[4-[(4-fluorophenyl)methoxy]-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;hydrochloride
Show/Hide
|
C33H39ClFNO5
|
1
|
| 1 |
EC50 = 2010 nM
|
|
|
|
CP0420400
|
3-[5-[[3-(3-chloropyridin-4-yl)phenyl]methoxy]thiophen-2-yl]propanoic acid
Show/Hide
|
C19H16ClNO3S
|
1
|
| 1 |
EC50 = 2010 nM
|
|
|
|
CP0435721
|
2-[4-[(3-phenoxyphenyl)methylamino]phenoxy]acetic acid
Show/Hide
|
C21H19NO4
|
2
|
| 1 |
EC50 = 2041 nM
|
|
|
| 2 |
EC50 = 2041.74 nM
|
|
|
|
CP0481380
|
3-[4-[[4-[[4-[2-(4-fluorophenoxy)ethyl]-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;hydrochloride
Show/Hide
|
C34H41ClFNO5
|
1
|
| 1 |
EC50 = 2060 nM
|
|
|
|
CP0498189
|
(3R)-3-[3-[[3-tert-butyl-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]-4,4,4-trifluorobutanoic acid
Show/Hide
|
C28H28F4O4
|
1
|
| 1 |
EC50 = 2100 nM
|
|
|
|
CP0535926
|
(3S)-3-[3-[[3-tert-butyl-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]-3-cyclohexylpropanoic acid
Show/Hide
|
C33H39FO4
|
1
|
| 1 |
EC50 = 2100 nM
|
|
|
|
CP0432418
|
3-ethoxy-3-[4-[(2-methylpyridin-3-yl)methoxy]phenyl]propanoic acid
Show/Hide
|
C18H21NO4
|
1
|
| 1 |
EC50 = 2100 nM
|
|
|
|
CP0572824
|
2-[4-[[3-(1,3-benzothiazol-2-yl)phenoxy]methyl]-2-fluorophenoxy]acetic acid
Show/Hide
|
C22H16FNO4S
|
1
|
| 1 |
EC50 = 2100 nM
|
|
|
|
CP0425290
|
3-[4-[[3-(4-fluoro-3-methylphenyl)-1,2,4-oxadiazol-5-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C19H17FN2O4
|
1
|
| 1 |
EC50 = 2120 nM
|
|
|
|
CP0455921
|
(1R,2R)-2-[3-[[3-(5,5-dimethylcyclopenten-1-yl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]-2-methylcyclopropane-1-carboxylic acid
Show/Hide
|
C32H33FO4
|
1
|
| 1 |
EC50 = 2130 nM
|
|
|
|
CP0542719
|
3-[4-[[5-[(4-methylphenoxy)methyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenyl]propanoic acid
Show/Hide
|
C20H19N3O4S
|
1
|
| 1 |
EC50 = 2170 nM
|
|
|
|
CP0494016
|
(3S)-3-[3-[[3-tert-butyl-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]-4-methylpentanoic acid
Show/Hide
|
C30H35FO4
|
1
|
| 1 |
EC50 = 2200 nM
|
|
|
|
CP0498188
|
(3R)-3-[4-[[4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]hex-4-ynoic acid
Show/Hide
|
C26H23FO4
|
1
|
| 1 |
EC50 = 2300 nM
|
|
|
|
CP0889402
|
(+/-)-3-(4-((3'-methoxybiphenyl-4-yl)methoxy)phenyl)hex-4-ynoic acid
Show/Hide
|
C26H24O4
|
1
|
| 1 |
EC50 = 2300 nM
|
|
|
|
CP0489236
|
3-[4-[[3-(2,6-dimethylphenyl)phenyl]methoxy]thiophen-2-yl]propanoic acid
Show/Hide
|
C22H22O3S
|
1
|
| 1 |
EC50 = 2320 nM
|
|
|
|
CP0558819
|
3-[4-[[4-[[4-(2-quinolin-2-yloxyethyl)-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;dihydrochloride
Show/Hide
|
C37H44Cl2N2O5
|
1
|
| 1 |
EC50 = 2360 nM
|
|
|
|
CP0444128
|
2-[(3S)-6-[3-(3-chlorophenoxy)propoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C19H19ClO5
|
1
|
| 1 |
EC50 = 2380 nM
|
|
|
|
CP0425289
|
3-[4-[1-(3-phenyl-1,2,4-oxadiazol-5-yl)ethoxy]phenyl]propanoic acid
Show/Hide
|
C19H18N2O4
|
1
|
| 1 |
EC50 = 2390 nM
|
|
|
|
CP0410973
|
3-[4-[[5-[(3-chlorophenyl)methyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenyl]propanoic acid
Show/Hide
|
C19H16ClN3O3S
|
1
|
| 1 |
EC50 = 2390 nM
|
|
|
|
CP0429680
|
3-[4-[[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenyl]propanoic acid
Show/Hide
|
C19H16ClN3O3S
|
1
|
| 1 |
EC50 = 2390 nM
|
|
|
|
CP0487767
|
3-[5-[[3-(2,6-dimethylphenyl)phenoxy]methyl]thiophen-2-yl]propanoic acid
Show/Hide
|
C22H22O3S
|
1
|
| 1 |
EC50 = 2420 nM
|
|
|
|
CP0429676
|
3-[4-[[5-[(4-methoxyphenoxy)methyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenyl]propanoic acid
Show/Hide
|
C20H19N3O5S
|
1
|
| 1 |
EC50 = 2430 nM
|
|
|
|
CP0489809
|
3-[4-(2,4-dichlorophenoxy)phenyl]butanoic acid
Show/Hide
|
C16H14Cl2O3
|
1
|
| 1 |
EC50 = 2484 nM
|
|
|
|
CP0415139
|
3-[6-[[3-(2,6-dimethylphenyl)phenyl]methoxy]-5-methylpyridin-3-yl]propanoic acid
Show/Hide
|
C24H25NO3
|
1
|
| 1 |
EC50 = 2500 nM
|
|
|
|
CP0477806
|
3-[4-[[5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenyl]propanoic acid
Show/Hide
|
C21H21N3O4S
|
1
|
| 1 |
EC50 = 2540 nM
|
|
|
|
CP0466155
|
3-[4-[[4-[[4-(2-pyridin-3-yloxyethyl)-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;dihydrochloride
Show/Hide
|
C33H42Cl2N2O5
|
1
|
| 1 |
EC50 = 2560 nM
|
|
|
|
CP0463219
|
3-[4-[(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)methoxy]phenyl]propanoic acid
Show/Hide
|
C16H14N2O4S
|
1
|
| 1 |
EC50 = 2570 nM
|
|
|
|
CP0481712
|
(3R)-3-ethoxy-3-[4-[[(1S)-4-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl]oxy]phenyl]propanoic acid
Show/Hide
|
C21H21F3O4
|
1
|
| 1 |
EC50 = 2600 nM
|
|
|
|
CP0392246
|
3-[4-[(5-phenyl-1,2,4-oxadiazol-3-yl)methoxy]phenyl]propanoic acid
Show/Hide
|
C18H16N2O4
|
1
|
| 1 |
EC50 = 2650 nM
|
|
|
|
CP0392252
|
3-[4-[[3-(3-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C19H18N2O5
|
1
|
| 1 |
EC50 = 2670 nM
|
|
|
|
CP0516620
|
3-(4-{[3-(1,3-Thiazol-2-yl)benzyl]oxy}phenyl)propanoic Acid
Show/Hide
|
C19H17NO3S
|
1
|
| 1 |
EC50 = 2700 nM
|
|
|
|
CP0543692
|
3-{4-[(3-Pyridin-2-ylbenzyl)oxy]phenyl}propanoic Acid
Show/Hide
|
C21H19NO3
|
1
|
| 1 |
EC50 = 2700 nM
|
|
|
|
CP0393669
|
3-[5-[[3-[2-(trifluoromethyl)phenyl]phenyl]methoxy]thiophen-2-yl]propanoic acid
Show/Hide
|
C21H17F3O3S
|
1
|
| 1 |
EC50 = 2710 nM
|
|
|
|
CP0410974
|
3-[4-[[5-[2-(4-chlorophenyl)-2-phenylethyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenyl]propanoic acid
Show/Hide
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C26H22ClN3O3S
|
1
|
| 1 |
EC50 = 2710 nM
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CP0455779
|
2-[6-[3-(3-phenylphenoxy)propoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C25H24O5
|
1
|
| 1 |
EC50 = 2760 nM
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CP0377838
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(1S,2R)-2-[4-[2-chloro-4-(trifluoromethyl)phenoxy]phenyl]-2-prop-1-ynylcyclopropane-1-carboxylic acid
Show/Hide
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C20H14ClF3O3
|
2
|
| 1 |
EC50 = 2820 nM
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| 2 |
IC50 = 3435 nM
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CP0511046
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3-[3-chloro-4-[[3-(3-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C19H17ClN2O5
|
1
|
| 1 |
EC50 = 3000 nM
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CP0457743
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2-[6-[3-(3-tert-butylphenoxy)propoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C23H28O5
|
1
|
| 1 |
EC50 = 3020 nM
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CP0476755
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2-[6-[3-(3-chlorophenoxy)propoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
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C19H19ClO5
|
1
|
| 1 |
EC50 = 3070 nM
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CP0532755
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3-[4-[[5-[[3-(trifluoromethyl)phenoxy]methyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenyl]propanoic acid
Show/Hide
|
C20H16F3N3O4S
|
1
|
| 1 |
EC50 = 3090 nM
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CP0432423
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3-[4-[(3,4-dichlorophenyl)methoxy]-3-nitrophenyl]-3-ethoxypropanoic acid
Show/Hide
|
C18H17Cl2NO6
|
1
|
| 1 |
EC50 = 3100 nM
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|
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CP0235368
|
3-(4-Phenoxy-phenyl)-propionic acid
Show/Hide
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C15H14O3
|
1
|
| 1 |
EC50 = 3200 nM
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CP0499547
|
3-[4-[(4-methoxyphenyl)methoxy]phenyl]pentanoic acid
Show/Hide
|
C19H22O4
|
1
|
| 1 |
EC50 = 3200 nM
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CP0431505
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3-[4-[(2,5-dimethylpyrazol-3-yl)methoxy]phenyl]-3-ethoxypropanoic acid
Show/Hide
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C17H22N2O4
|
1
|
| 1 |
EC50 = 3200 nM
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|
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CP0577388
|
2-[4-[[3-(1,3-benzoxazol-6-yl)phenyl]methoxy]-2-fluorophenoxy]acetic acid
Show/Hide
|
C22H16FNO5
|
1
|
| 1 |
EC50 = 3240 nM
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|
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CP0477790
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3-[4-[[5-[(3-methylphenoxy)methyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenyl]propanoic acid
Show/Hide
|
C20H19N3O4S
|
1
|
| 1 |
EC50 = 3260 nM
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CP0945997
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3-(4-(3-(3-chlorophenoxy)propoxy)phenyl)propanoic-2,2-d2 acid
Show/Hide
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C18H19ClO4
|
1
|
| 1 |
EC50 = 3280 nM
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CP0411699
|
2-[6-[3-(3-bromophenoxy)propoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C19H19BrO5
|
1
|
| 1 |
EC50 = 3450 nM
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CP0558597
|
8-[4-[2,3-difluoro-5-(3-methoxycyclobutyl)oxyphenyl]-2,6-difluorophenoxy]octanoic acid
Show/Hide
|
C25H28F4O5
|
1
|
| 1 |
EC50 = 3480 nM
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|
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CP0395985
|
3-(4-phenethoxyphenyl)propanoic acid
Show/Hide
|
C17H18O3
|
1
|
| 1 |
EC50 = 3500 nM
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|
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CP0476579
|
3-(4-(3-phenylpropoxy)phenyl)propanoic acid
Show/Hide
|
C18H20O3
|
1
|
| 1 |
EC50 = 3500 nM
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CP0438830
|
7-[4-[2,3-difluoro-5-(3-methoxycyclobutyl)oxyphenyl]-2,6-difluorophenoxy]heptanoic acid
Show/Hide
|
C24H26F4O5
|
1
|
| 1 |
EC50 = 3500 nM
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|
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CP0411710
|
2-[6-[3-(3-methylphenoxy)propoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C20H22O5
|
1
|
| 1 |
EC50 = 3590 nM
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|
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CP0406070
|
3-[4-(Biphenyl-2-ylmethoxy)phenyl]propanoic Acid
Show/Hide
|
C22H20O3
|
1
|
| 1 |
EC50 = 3600 nM
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|
|
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CP0415824
|
3-[4-[(5-benzyl-1,3,4-thiadiazole-2-carbonyl)amino]phenyl]propanoic acid
Show/Hide
|
C19H17N3O3S
|
1
|
| 1 |
EC50 = 3670 nM
|
|
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CP0420100
|
3-[4-[[5-[(4-chlorophenyl)carbamoyl]-1,3,4-thiadiazol-2-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C19H16ClN3O4S
|
1
|
| 1 |
EC50 = 3690 nM
|
|
|
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CP0524463
|
(3R)-3-[3-[[3-tert-butyl-4-(6-methoxypyridin-2-yl)phenyl]methoxy]phenyl]hexanoic acid
Show/Hide
|
C29H35NO4
|
1
|
| 1 |
EC50 = 3700 nM
|
|
|
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CP0439334
|
2-[4-[2-(2-methylphenyl)ethynyl]phenoxy]acetic acid
Show/Hide
|
C17H14O3
|
1
|
| 1 |
EC50 = 3715 nM
|
|
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CP0446307
|
(1'R,3S)-5-[[3-(5,5-dimethylcyclopenten-1-yl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]spiro[1,2-dihydroindene-3,2'-cyclopropane]-1'-carboxylic acid
Show/Hide
|
C33H33FO4
|
1
|
| 1 |
EC50 = 3780 nM
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|
|
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CP0431851
|
3-ethoxy-2,2-difluoro-3-[4-[(2-methylphenyl)methoxy]phenyl]propanoic acid
Show/Hide
|
C19H20F2O4
|
1
|
| 1 |
EC50 = 3800 nM
|
|
|
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CP0411709
|
2-[6-[2-(3-tert-butylphenoxy)ethoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C22H26O5
|
1
|
| 1 |
EC50 = 3850 nM
|
|
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CP0519596
|
3-[4-[[4-[[4-(2-pyrimidin-2-yloxyethyl)-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;dihydrochloride
Show/Hide
|
C32H41Cl2N3O5
|
1
|
| 1 |
EC50 = 3870 nM
|
|
|
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CP0393947
|
3-cyclopropyl-3-[5-[[3-(2,6-dimethylphenyl)phenyl]methoxy]thiophen-2-yl]propanoic acid
Show/Hide
|
C25H26O3S
|
1
|
| 1 |
EC50 = 3920 nM
|
|
|
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CP0452574
|
(3R)-3-[4-[[4-(3-methoxyphenyl)phenyl]methoxy]phenyl]hex-4-ynoic acid
Show/Hide
|
C26H24O4
|
1
|
| 1 |
EC50 = 4000 nM
|
|
|
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CP0443647
|
3-[4-[1-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)ethoxy]phenyl]propanoic acid
Show/Hide
|
C17H16N2O4S
|
1
|
| 1 |
EC50 = 4000 nM
|
|
|
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CP0555466
|
3-[4-[[5-[2-(1,3-benzodioxol-5-yl)-2-phenylethyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenyl]propanoic acid
Show/Hide
|
C27H23N3O5S
|
1
|
| 1 |
EC50 = 4120 nM
|
|
|
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CP0570173
|
2-[4-[[3-ethoxy-5-[(E)-2-(4-ethoxyphenyl)ethenyl]phenoxy]methyl]-2-fluorophenoxy]acetic acid
Show/Hide
|
C27H27FO6
|
1
|
| 1 |
EC50 = 4200 nM
|
|
|
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CP0411698
|
2-[6-[3-(4-phenylphenoxy)propoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C25H24O5
|
1
|
| 1 |
EC50 = 4260 nM
|
|
|
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CP0488959
|
3-[4-[[5-[(4-methylphenyl)carbamoyl]-1,3,4-thiadiazol-2-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C20H19N3O4S
|
1
|
| 1 |
EC50 = 4300 nM
|
|
|
|
CP0446110
|
3-[4-[[4-[[4-[(3-cyclopropyl-1,2,4-oxadiazol-5-yl)methyl]-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;hydrochloride
Show/Hide
|
C32H40ClN3O5
|
1
|
| 1 |
EC50 = 4540 nM
|
|
|
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CP0392251
|
3-[3-chloro-4-[[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C19H17ClN2O4
|
1
|
| 1 |
EC50 = 4580 nM
|
|
|
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CP0498058
|
3-[4-[[5-[(3-methoxyphenyl)carbamoyl]-1,3,4-thiadiazol-2-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C20H19N3O5S
|
1
|
| 1 |
EC50 = 4680 nM
|
|
|
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CP0399437
|
3-[4-[[5-(3,5-dimethyl-1,2-oxazol-4-yl)pyridin-3-yl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
|
C20H19FN2O4
|
1
|
| 1 |
EC50 = 4980 nM
|
|
|
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CP0415825
|
3-[4-[[5-[(3-fluorophenyl)methyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenyl]propanoic acid
Show/Hide
|
C19H16FN3O3S
|
1
|
| 1 |
EC50 = 5020 nM
|
|
|
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CP0532756
|
3-[4-[[5-[(4-fluorophenoxy)methyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenyl]propanoic acid
Show/Hide
|
C19H16FN3O4S
|
1
|
| 1 |
EC50 = 5390 nM
|
|
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CP0432417
|
(3S)-3-[4-(6,7-dihydro-5H-cyclopenta[b]pyridin-5-yloxy)phenyl]-3-ethoxypropanoic acid
Show/Hide
|
C19H21NO4
|
1
|
| 1 |
EC50 = 5600 nM
|
|
|
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CP0481379
|
3-[4-[[4-[[4-(2-pyridin-4-yloxyethyl)-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;dihydrochloride
Show/Hide
|
C33H42Cl2N2O5
|
1
|
| 1 |
EC50 = 6100 nM
|
|
|
|
CP0392992
|
3-[4-(2-phenylethoxy)phenyl]hex-4-ynoic acid
Show/Hide
|
C20H20O3
|
1
|
| 1 |
EC50 = 6200 nM
|
|
|
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CP0498061
|
3-[4-[[5-[(4-fluorophenyl)carbamoyl]-1,3,4-thiadiazol-2-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C19H16FN3O4S
|
1
|
| 1 |
EC50 = 6640 nM
|
|
|
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CP0496054
|
(3R)-3-[4-[(4-methoxyphenyl)methoxy]phenyl]hex-4-ynoic acid
Show/Hide
|
C20H20O4
|
1
|
| 1 |
EC50 = 6700 nM
|
|
|
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CP0569334
|
2-[4-[[3-(5-chloro-1,3-benzoxazol-2-yl)phenoxy]methyl]-2-fluorophenoxy]acetic acid
Show/Hide
|
C22H15ClFNO5
|
1
|
| 1 |
EC50 = 6800 nM
|
|
|
|
CP0915705
|
trans-rac-5-(1-(4-(2-(difluoromethoxy)-4-(trifluoromethyl)phenoxy)phenyl)but-2-ynyl)oxazolidine-2,4-dione
Show/Hide
|
C21H14F5NO5
|
2
|
| 1 |
EC50 = 7581 nM
|
|
|
| 2 |
IC50 = 2414 nM
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|
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CP0457744
|
2-[6-[3-(4-methylphenoxy)propoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C20H22O5
|
1
|
| 1 |
EC50 = 7620 nM
|
|
|
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CP0960219
|
3-(4-((4-Fluoro-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic-2,2-d2 acid
Show/Hide
|
C22H19FO3
|
1
|
| 1 |
EC50 = 7900 nM
|
|
|
|
CP0438102
|
2-[4-[3-(3-chlorophenoxy)propoxy]-2-fluorophenoxy]acetic acid
Show/Hide
|
C17H16ClFO5
|
1
|
| 1 |
EC50 = 8450 nM
|
|
|
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CP0477465
|
2-[(8S)-3-(4-bromophenyl)-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
Show/Hide
|
C18H15BrO5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0475702
|
3-[4-[[5-[(4-methoxyphenyl)carbamoyl]-1,3,4-thiadiazol-2-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C20H19N3O5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0402723
|
3-[2-(4-chlorophenyl)-1-methylindol-5-yl]propanoic acid
Show/Hide
|
C18H16ClNO2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0482615
|
3-[2-(3-chlorophenyl)-1-methylindol-5-yl]propanoic acid
Show/Hide
|
C18H16ClNO2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0533315
|
3-[2-(2-bromophenyl)-1-methylindol-5-yl]propanoic acid
Show/Hide
|
C18H16BrNO2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0410972
|
2-[4-[[5-[(3-methoxyphenyl)carbamoyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenoxy]acetic acid
Show/Hide
|
C19H16N4O6S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0415819
|
2-[4-[[5-[(4-ethoxycarbonylphenyl)carbamoyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenoxy]acetic acid
Show/Hide
|
C21H18N4O7S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0415820
|
2-[4-[[5-[(4-chlorophenyl)carbamoyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenoxy]acetic acid
Show/Hide
|
C18H13ClN4O5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0415821
|
2-[4-[[5-[(3-methylphenyl)carbamoyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenoxy]acetic acid
Show/Hide
|
C19H16N4O5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0415826
|
2-[4-[[5-[(3,4-dimethylphenyl)carbamoyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenoxy]acetic acid
Show/Hide
|
C20H18N4O5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0429674
|
2-[4-[[5-[(2-methoxy-5-methylphenyl)carbamoyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenoxy]acetic acid
Show/Hide
|
C20H18N4O6S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0429678
|
2-[4-[[5-[(4-bromophenyl)carbamoyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenoxy]acetic acid
Show/Hide
|
C18H13BrN4O5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0429679
|
2-[4-[[5-[(3-ethoxycarbonylphenyl)carbamoyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenoxy]acetic acid
Show/Hide
|
C21H18N4O7S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0477807
|
2-[4-[[5-[(2,4-difluorophenyl)carbamoyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenoxy]acetic acid
Show/Hide
|
C18H12F2N4O5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0532757
|
2-[4-[[5-(phenylcarbamoyl)-1,3,4-thiadiazole-2-carbonyl]amino]phenoxy]acetic acid
Show/Hide
|
C18H14N4O5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0538707
|
2-[4-[[5-[(3,4-difluorophenyl)carbamoyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenoxy]acetic acid
Show/Hide
|
C18H12F2N4O5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0542718
|
2-[4-[[5-[(4-methylphenyl)carbamoyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenoxy]acetic acid
Show/Hide
|
C19H16N4O5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0549563
|
2-[4-[[5-[(4-fluorophenyl)carbamoyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenoxy]acetic acid
Show/Hide
|
C18H13FN4O5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0558100
|
2-[4-[[5-[(2,3-dimethylphenyl)carbamoyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenoxy]acetic acid
Show/Hide
|
C20H18N4O5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0563804
|
2-[4-[[5-[(2-methylphenyl)carbamoyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenoxy]acetic acid
Show/Hide
|
C19H16N4O5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0564258
|
2-[4-[[5-[(5-methyl-1,3,4-thiadiazol-2-yl)carbamoyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenoxy]acetic acid
Show/Hide
|
C15H12N6O5S2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0574480
|
2-[4-[[5-[(2-fluorophenyl)carbamoyl]-1,3,4-thiadiazole-2-carbonyl]amino]phenoxy]acetic acid
Show/Hide
|
C18H13FN4O5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0377039
|
2-[(1S)-5-(3-phenoxypropoxy)-2,3-dihydro-1H-inden-1-yl]acetic acid
Show/Hide
|
C20H22O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0411700
|
2-[2-methyl-4-[3-(4-phenylphenoxy)propoxy]phenoxy]acetic acid
Show/Hide
|
C24H24O5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0421259
|
2-[4-[3-(3-chlorophenoxy)propoxy]-2-methylphenoxy]acetic acid
Show/Hide
|
C18H19ClO5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0421260
|
2-[6-[3-(2-fluorophenoxy)propoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C19H19FO5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0457742
|
2-[6-(3-phenoxypropoxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C19H20O5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0466657
|
2-[6-(2-phenoxyethoxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C18H18O5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0476754
|
2-[6-[3-(2-methylphenoxy)propoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid
Show/Hide
|
C20H22O5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0489509
|
2-[4-[3-(3-chlorophenoxy)propoxy]phenyl]sulfonylacetic acid
Show/Hide
|
C17H17ClO6S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0434415
|
2-[2-fluoro-4-[(2-phenyl-1,3-thiazol-4-yl)methoxy]phenoxy]acetic acid
Show/Hide
|
C18H14FNO4S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0434417
|
2-[2-fluoro-4-[(5-phenyl-1,3,4-oxadiazol-2-yl)methoxy]phenoxy]acetic acid
Show/Hide
|
C17H13FN2O5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0434418
|
2-[2-fluoro-4-[(5-methyl-2-phenyl-1,3-thiazol-4-yl)methylamino]phenoxy]acetic acid
Show/Hide
|
C19H17FN2O3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0434419
|
2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methoxy]phenoxy]acetic acid
Show/Hide
|
C21H18F3NO4S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0468911
|
2-[2-fluoro-4-[(5-phenyl-1,3,4-thiadiazol-2-yl)methoxy]phenoxy]acetic acid
Show/Hide
|
C17H13FN2O4S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0473349
|
2-[2-methyl-4-[(2-phenyl-1,3-thiazol-4-yl)methoxy]phenoxy]acetic acid
Show/Hide
|
C19H17NO4S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0473350
|
2-[2-methyl-4-[(5-phenyl-1,3-oxazol-2-yl)methoxy]phenoxy]acetic acid
Show/Hide
|
C19H17NO5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0473351
|
2-[2-fluoro-4-[(5-phenyl-1,3-thiazol-2-yl)methoxy]phenoxy]acetic acid
Show/Hide
|
C18H14FNO4S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0473352
|
2-[2-fluoro-4-[(5-phenyl-1,3-oxazol-2-yl)methoxy]phenoxy]acetic acid
Show/Hide
|
C18H14FNO5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0473354
|
2-[2-methyl-4-[(4-methyl-2-phenyl-1,3-thiazol-5-yl)methoxy]phenoxy]acetic acid
Show/Hide
|
C20H19NO4S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0477340
|
2-[2-methyl-4-[(5-phenyl-1,3,4-thiadiazol-2-yl)methoxy]phenoxy]acetic acid
Show/Hide
|
C18H16N2O4S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0479822
|
2-[2-fluoro-4-[(5-methyl-2-phenyl-1,3-thiazol-4-yl)methoxy]phenoxy]acetic acid
Show/Hide
|
C19H16FNO4S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0479825
|
2-[2-fluoro-4-[(4-phenyl-1,3-thiazol-2-yl)methoxy]phenoxy]acetic acid
Show/Hide
|
C18H14FNO4S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0579567
|
2-[4-[[3-methoxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]phenoxy]methyl]phenoxy]acetic acid
Show/Hide
|
C25H24O6
|
1
|
| 1 |
EC50 = 10300 nM
|
|
|
|
CP0902466
|
3-(4-((4'-Methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic-2,2-d2 acid
Show/Hide
|
C23H22O3
|
1
|
| 1 |
EC50 = 10500 nM
|
|
|
|
CP0054883
|
3-[4-[[5-[(3-chlorophenyl)carbamoyl]-1,3,4-thiadiazol-2-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C19H16ClN3O4S
|
1
|
| 1 |
EC50 = 10620 nM
|
|
|
|
CP0456326
|
6-[4-[2,3-difluoro-5-(3-methoxycyclobutyl)oxyphenyl]-2,6-difluorophenoxy]hexanoic acid
Show/Hide
|
C23H24F4O5
|
1
|
| 1 |
EC50 = 11010 nM
|
|
|
|
CP0392250
|
3-[3-chloro-4-[(3-phenyl-1,2,4-oxadiazol-5-yl)methoxy]phenyl]propanoic acid
Show/Hide
|
C18H15ClN2O4
|
1
|
| 1 |
EC50 = 13100 nM
|
|
|
|
CP0393951
|
3-[4-[[3-(2,6-dimethylphenyl)phenoxy]methyl]triazol-1-yl]propanoic acid
Show/Hide
|
C20H21N3O3
|
1
|
| 1 |
EC50 = 14700 nM
|
|
|
|
CP0475988
|
3-[4-[[3-(2,6-dimethylphenyl)phenyl]methoxy]triazol-1-yl]propanoic acid
Show/Hide
|
C20H21N3O3
|
1
|
| 1 |
EC50 = 14800 nM
|
|
|
|
CP0493935
|
3-[5-[(4-phenylmethoxyphenyl)carbamoyl]-1,3,4-thiadiazol-2-yl]propanoic acid
Show/Hide
|
C19H17N3O4S
|
1
|
| 1 |
EC50 = 17940 nM
|
|
|
|
CP0930429
|
3-(4-([1,1'-Biphenyl]-2-ylmethoxy)phenyl)propanoic-2,2-d2 acid
Show/Hide
|
C22H20O3
|
1
|
| 1 |
EC50 = 18600 nM
|
|
|
|
CP0472628
|
2-[4-[[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]methoxy]phenyl]acetic acid
Show/Hide
|
C17H13ClN2O4
|
1
|
| 1 |
EC50 = 18800 nM
|
|
|
|
CP0400944
|
3-[4-[[4-[[4-(cyclopropylmethoxy)-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;hydrochloride
Show/Hide
|
C30H40ClNO5
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0432770
|
3-[4-[[4-[[4-[[3-(2-methoxyethyl)-1,2,4-oxadiazol-5-yl]methyl]-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;hydrochloride
Show/Hide
|
C32H42ClN3O6
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0446111
|
3-[4-[[4-[[4-[(3-fluorophenyl)methyl]-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;hydrochloride
Show/Hide
|
C33H39ClFNO4
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0508325
|
3-[4-[[4-[(4-methoxy-1-oxa-9-azaspiro[5.5]undecan-9-yl)methyl]phenyl]methoxy]phenyl]propanoic acid;hydrochloride
Show/Hide
|
C27H36ClNO5
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0543472
|
3-[4-[[4-[[4-[[4-(trifluoromethyl)phenyl]methoxy]-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;hydrochloride
Show/Hide
|
C34H39ClF3NO5
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0558048
|
3-[4-[[4-[(4-methyl-1-oxa-9-azaspiro[5.5]undecan-9-yl)methyl]phenyl]methoxy]phenyl]propanoic acid;hydrochloride
Show/Hide
|
C27H36ClNO4
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0558049
|
3-[4-[[4-[(4-ethoxy-1-oxa-9-azaspiro[5.5]undecan-9-yl)methyl]phenyl]methoxy]phenyl]propanoic acid;hydrochloride
Show/Hide
|
C28H38ClNO5
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0567231
|
3-[4-[[4-[[4-[(3-pyridin-3-yl-1,2,4-oxadiazol-5-yl)methyl]-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;hydrochloride
Show/Hide
|
C34H39ClN4O5
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0958439
|
3-(4-{[4-(1-Oxa-9-azaspiro[5.5]undec-9-ylmethyl)benzyl]oxy}phenyl)propanoic acid hydrochloride
Show/Hide
|
C26H34ClNO4
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0410166
|
3-[4-[[4-(1-oxa-9-azaspiro[5.5]undecan-9-ylmethyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C26H34ClNO4
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0443185
|
(3S)-3-(1-methylimidazol-2-yl)-3-[4-[[3-(2-methylsulfonylphenyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C27H26N2O5S
|
1
|
| 1 |
EC50 = 23000 nM
|
|
|
|
CP0438829
|
4-[4-(2,3-difluoro-5-methoxyphenyl)-2,6-difluorophenoxy]butanoic acid
Show/Hide
|
C17H14F4O4
|
1
|
| 1 |
EC50 = 24430 nM
|
|
|
|
CP0483433
|
(1R,2R)-2-[4-[2-chloro-4-(trifluoromethyl)phenoxy]phenyl]-2-prop-1-ynylcyclopropane-1-carboxylic acid
Show/Hide
|
C20H14ClF3O3
|
2
|
| 1 |
EC50 = 24490 nM
|
|
|
| 2 |
IC50 = 10000 nM
|
|
|
|
CP0452172
|
3-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]hex-4-ynoic acid
Show/Hide
|
C20H17F3O3
|
1
|
| 1 |
EC50 = 27000 nM
|
|
|
|
CP0487115
|
4-[2,6-difluoro-4-[5-(3-methoxycyclobutyl)oxy-2-nitrophenyl]phenoxy]butanoic acid
Show/Hide
|
C21H21F2NO7
|
1
|
| 1 |
EC50 = 29350 nM
|
|
|
|
CP0396321
|
(1R,1aS,6aR)-3-[[3-(5,5-dimethylcyclopenten-1-yl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]-1,1a,6,6a-tetrahydrocyclopropa[a]indene-1-carboxylic acid
Show/Hide
|
C32H31FO4
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0397564
|
(1R,1aR,6aS)-3-[[3-(5,5-dimethylcyclopenten-1-yl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]-1,1a,6,6a-tetrahydrocyclopropa[a]indene-1-carboxylic acid
Show/Hide
|
C32H31FO4
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0404842
|
(1'S,3S)-5-[[3-(5,5-dimethylcyclopenten-1-yl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]spiro[1,2-dihydroindene-3,2'-cyclopropane]-1'-carboxylic acid
Show/Hide
|
C33H33FO4
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0407387
|
(1S,1aR,6aS)-3-[[3-(5,5-dimethylcyclopenten-1-yl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]-1,1a,6,6a-tetrahydrocyclopropa[a]indene-1-carboxylic acid
Show/Hide
|
C32H31FO4
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0465261
|
(1'S,3R)-5-[[3-(5,5-dimethylcyclopenten-1-yl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]spiro[1,2-dihydroindene-3,2'-cyclopropane]-1'-carboxylic acid
Show/Hide
|
C33H33FO4
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0415644
|
(3R)-3-[3-[[3-tert-butyl-4-(5-methoxypyridin-3-yl)phenyl]methoxy]phenyl]hexanoic acid
Show/Hide
|
C29H35NO4
|
1
|
| 1 |
EC50 = 30000 nM
|
|
|
|
CP0425295
|
3-[3-chloro-4-[[3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C19H14ClF3N2O4
|
1
|
| 1 |
EC50 = 30100 nM
|
|
|
|
CP0420402
|
3-[1-[[3-(2,6-dimethylphenyl)phenoxy]methyl]triazol-4-yl]propanoic acid
Show/Hide
|
C20H21N3O3
|
1
|
| 1 |
EC50 = 32200 nM
|
|
|
|
CP0481381
|
3-[4-[[4-[[4-[2-[5-(trifluoromethyl)pyridin-2-yl]oxyethyl]-1-oxa-9-azaspiro[5.5]undecan-9-yl]methyl]phenyl]methoxy]phenyl]propanoic acid;dihydrochloride
Show/Hide
|
C34H41Cl2F3N2O5
|
1
|
| 1 |
EC50 = 33500 nM
|
|
|
|
CP0030287
|
(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid
Show/Hide
|
C22H32O2
|
1
|
| 1 |
EC50 = 36000 nM
|
|
|
|
CP0393672
|
(3S)-3-[5-[[3-(2,6-dimethylphenyl)phenyl]methoxy]thiophen-2-yl]-3-ethoxypropanoic acid
Show/Hide
|
C24H26O4S
|
1
|
| 1 |
EC50 = 40100 nM
|
|
|
|
CP0388806
|
3-[4-[[5-(3-chlorophenyl)-1,3-oxazol-2-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C19H16ClNO4
|
1
|
| 1 |
EC50 = 47500 nM
|
|
|
|
CP0145583
|
3-[4-[[5-fluoro-2-(4-methylphenyl)phenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C23H21FO3
|
1
|
| 1 |
EC50 = 52600 nM
|
|
|
|
CP0435993
|
5-[4-[2,3-difluoro-5-(3-methoxycyclobutyl)oxyphenyl]-2,6-difluorophenoxy]pentanoic acid
Show/Hide
|
C22H22F4O5
|
1
|
| 1 |
EC50 = 68780 nM
|
|
|
|
CP0860299
|
3-(4-((4-Fluoro-4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic-2,2-d2 acid
Show/Hide
|
C23H21FO3
|
1
|
| 1 |
EC50 = 75900 nM
|
|
|
|
CP0425294
|
3-[4-[[3-(furan-2-yl)-1,2,4-oxadiazol-5-yl]methoxy]phenyl]propanoic acid
Show/Hide
|
C16H14N2O5
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0412528
|
CHEMBL4250664
Show/Hide
|
C22H22F2O7
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0427750
|
CHEMBL4239630
Show/Hide
|
C23H26F2O5
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0427751
|
4-[4-[2,3-difluoro-5-(3-methoxycyclobutyl)oxyphenyl]-2,6-difluorophenyl]sulfanylbutanoic acid
Show/Hide
|
C21H20F4O4S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0478430
|
4-[4-[2,3-difluoro-5-(3-methoxycyclobutyl)oxyphenyl]-2,6-difluorophenoxy]butanoic acid
Show/Hide
|
C21H20F4O5
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0478431
|
4-[4-[2,3-difluoro-5-(3-methoxycyclobutyl)oxyphenyl]-2,6-difluorophenoxy]-2,2-dimethylbutanoic acid
Show/Hide
|
C23H24F4O5
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0487116
|
3-[(2R)-6-[2,3-difluoro-5-(3-methoxycyclobutyl)oxyphenyl]-3,4-dihydro-2H-chromen-2-yl]propanoic acid
Show/Hide
|
C23H24F2O5
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0487158
|
4-[2,6-difluoro-4-[2-(propan-2-ylamino)phenyl]phenoxy]butanoic acid
Show/Hide
|
C19H21F2NO3
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0555832
|
4-[4-[2,3-difluoro-5-(oxan-4-yloxy)phenyl]-2,6-difluorophenoxy]butanoic acid
Show/Hide
|
C21H20F4O5
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0402726
|
3-[2-(2-methylpyridin-3-yl)-1H-indol-5-yl]propanoic acid
Show/Hide
|
C17H16N2O2
|
1
|
| 1 |
EC50 > 25 nM
|
|
|
|
CP0412749
|
3-[2-(2-propan-2-ylphenyl)-1H-indol-5-yl]propanoic acid
Show/Hide
|
C20H21NO2
|
1
|
| 1 |
EC50 > 25 nM
|
|
|
|
CP0459095
|
3-[2-(4-methoxyphenyl)-1H-indol-5-yl]propanoic acid
Show/Hide
|
C18H17NO3
|
1
|
| 1 |
EC50 > 25 nM
|
|
|
|
CP0459098
|
3-[2-(4-methylphenyl)-1H-indol-5-yl]propanoic acid
Show/Hide
|
C18H17NO2
|
1
|
| 1 |
EC50 > 25 nM
|
|
|
|
CP0518109
|
3-[2-(3-methylphenyl)-1H-indol-5-yl]propanoic acid
Show/Hide
|
C18H17NO2
|
1
|
| 1 |
EC50 > 25 nM
|
|
|
|
CP0518110
|
3-[2-(2-methoxyphenyl)-1H-indol-5-yl]propanoic acid
Show/Hide
|
C18H17NO3
|
1
|
| 1 |
EC50 > 25 nM
|
|
|
|
CP0518111
|
3-[2-(3-methoxyphenyl)-1H-indol-5-yl]propanoic acid
Show/Hide
|
C18H17NO3
|
1
|
| 1 |
EC50 > 25 nM
|
|
|
|
CP0518112
|
3-(2-phenyl-1H-indol-5-yl)propanoic acid
Show/Hide
|
C17H15NO2
|
1
|
| 1 |
EC50 > 25 nM
|
|
|
|
CP0479613
|
3-[2-(2,5-dimethylphenyl)-1-methylindol-5-yl]propanoic acid
Show/Hide
|
C20H21NO2
|
1
|
| 1 |
EC50 > 25 nM
|
|
|
|
CP0514815
|
3-[2-(3-chloropyridin-4-yl)-1H-indol-5-yl]propanoic acid
Show/Hide
|
C16H13ClN2O2
|
1
|
| 1 |
EC50 > 25 nM
|
|
|
|
CP0547964
|
3-[2-(2,5-dichlorophenyl)-1H-indol-5-yl]propanoic acid
Show/Hide
|
C17H13Cl2NO2
|
1
|
| 1 |
EC50 > 25 nM
|
|
|
|
CP0547965
|
3-[2-(3-chloro-2-fluorophenyl)-1H-indol-5-yl]propanoic acid
Show/Hide
|
C17H13ClFNO2
|
1
|
| 1 |
EC50 > 25 nM
|
|
|
|
CP0547979
|
3-[2-(4-chloro-2-fluorophenyl)-1H-indol-5-yl]propanoic acid
Show/Hide
|
C17H13ClFNO2
|
1
|
| 1 |
EC50 > 25 nM
|
|
|
|
CP0551565
|
3-[2-(4-fluoro-2-methylphenyl)-1-methylindol-5-yl]propanoic acid
Show/Hide
|
C19H18FNO2
|
1
|
| 1 |
EC50 > 25 nM
|
|
|
|
CP0557744
|
3-[2-[4-chloro-2-(trifluoromethyl)phenyl]-1H-indol-5-yl]propanoic acid
Show/Hide
|
C18H13ClF3NO2
|
1
|
| 1 |
EC50 > 25 nM
|
|
|
|
CP0415872
|
2-[3-[[4-(2-methylphenyl)phenyl]methoxy]phenyl]sulfonylacetic acid
Show/Hide
|
C22H20O5S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0415873
|
1-[4-[[3-(4-methoxy-2,6-dimethylphenyl)phenyl]methoxy]phenyl]sulfonylcyclopropane-1-carboxylic acid
Show/Hide
|
C26H26O6S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0538723
|
2-[4-[[3-(4-methoxy-2,6-dimethylphenyl)phenyl]methoxy]phenyl]sulfonylpropanoic acid
Show/Hide
|
C25H26O6S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0545218
|
2-[6-[[3-(4-methoxy-2,6-dimethylphenyl)phenyl]methoxy]-1,1-dioxo-2,3-dihydro-1-benzothiophen-3-yl]acetic acid
Show/Hide
|
C26H26O6S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0558104
|
2-[4-[[3-(4-methoxy-2,6-dimethylphenyl)phenyl]methoxy]phenyl]sulfonyl-2-methylpropanoic acid
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|
C26H28O6S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0564012
|
2-[3-[(4-phenylphenyl)methoxy]phenyl]sulfonylacetic acid
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|
C21H18O5S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0564016
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2-[(3E)-5-[[3-(4-methoxy-2,6-dimethylphenyl)phenyl]methoxy]-3-methoxyimino-1,2-dihydroinden-1-yl]acetic acid
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|
C28H29NO5
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0574145
|
2-[4-[[3-(4-methoxy-2,6-dimethylphenyl)phenyl]methoxy]phenyl]sulfonylbutanoic acid
Show/Hide
|
C26H28O6S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0523189
|
2-[4-[[3-(4-ethoxy-2,6-dimethylphenyl)phenyl]methoxy]-2-fluoroanilino]acetic acid
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|
C25H26FNO4
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0398873
|
2-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylamino]phenyl]acetic acid
Show/Hide
|
C20H17F3N2O2S
|
1
|
| 1 |
EC50 < 10000 nM
|
|
|
|
CP0441502
|
4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylamino]benzoic acid
Show/Hide
|
C19H15F3N2O2S
|
1
|
| 1 |
EC50 < 10000 nM
|
|
|
|
CP0457011
|
4-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylamino]phenyl]butanoic acid
Show/Hide
|
C22H21F3N2O2S
|
1
|
| 1 |
EC50 < 10000 nM
|
|
|
|
CP0459741
|
4-(3-Phenoxybenzylamino)Benzoic Acid
Show/Hide
|
C20H17NO3
|
1
|
| 1 |
EC50 < 10000 nM
|
|
|
|
CP0466852
|
2-(4-{[(3-phenoxyphenyl)methyl]amino}phenyl)acetic acid
Show/Hide
|
C21H19NO3
|
1
|
| 1 |
EC50 < 10000 nM
|
|
|
|
CP0492618
|
2-methyl-2-[4-[(3-phenoxyphenyl)methylamino]phenoxy]propanoic acid
Show/Hide
|
C23H23NO4
|
1
|
| 1 |
EC50 < 10000 nM
|
|
|
|
CP0508631
|
3-[4-[[3-(2,6-dimethylphenyl)-5-methoxyphenyl]methoxy]-2-fluorophenyl]propanoic acid
Show/Hide
|
C25H25FO4
|
1
|
| 1 |
Ki = 99 nM
|
|
|
|
CP0486908
|
3-[4-[[5-(2,6-dimethylphenyl)-2-methoxyphenyl]methoxy]phenyl]propanoic acid
Show/Hide
|
C25H26O4
|
1
|
| 1 |
Ki = 520 nM
|
|
|
|
CP0389834
|
2-[5-[[3-(2,6-dimethylphenyl)phenyl]methoxy]indol-1-yl]acetic acid
Show/Hide
|
C25H23NO3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0476020
|
2-[5-[[3-[4-(2-ethoxyethoxy)-2,6-dimethylphenyl]phenyl]methoxy]-2-oxo-3H-indol-1-yl]acetic acid
Show/Hide
|
C29H31NO6
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
