Brief Information of the Compound and Protein
Compound Name
3-{4-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]-2-fluorophenyl}propanoic Acid
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PubChem ID
CID: 51350138
SID: 121268143
Canonical SMILES
Cc1cccc(C)c1-c1cccc(COc2ccc(CCC(O)=O)c(F)c2)c1
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Compound Formula C24H23FO3
Compound Structure
Protein Name
Free fatty acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Free fatty acid receptor
Uniprot ID
O14842
Gene Name
FFAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  1
1
EC50 = 6.026 nM
   TI
   LI
   LO
   TS
CL000011 CHO Cricetulus griseus (Chinese hamster)  5
1
EC50 = 5.7 nM
   TI
   LI
   LO
   TS
2
EC50 = 7.7 nM
   TI
   LI
   LO
   TS
3
EC50 = 14.2 nM
   TI
   LI
   LO
   TS
4
EC50 = 30 nM
   TI
   LI
   LO
   TS
5
Ki = 32 nM
   TI
   LI
   LO
   TS
CL000460 Flp-In-T-REx-293 Homo sapiens (Human)  1
1
EC50 = 34.67 nM
   TI
   LI
   LO
   TS