Brief Information of the Cell Line and Protein
Cell Line ID: CL000007 , HT-29
Synonyms
HT 29
HT29
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0320
Protein ID: PT02429 , Neurotensin receptor type 1
Gene Name NTSR1
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P30989
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000007  Protein ID: PT02429
 
Compound ID Compound Name Compound Formula
CP0212154
(S)-2-((2S,3R)-2-((S)-2-((S)-1-((S)-2-((S)-2-azido-5-guanidinopentanamido)-5-guanidinopentanoyl)pyrrolidine-2-carboxamido)-3-(4-hydroxyphenyl)propanamido)-3-methylpentanamido)-4-methylpentanoic acid
   Show/Hide
C38H62N14O8
 1
1
EC50 = 0.78 nM
   TI
   LI
   LO
   TS
CP0339682
(S)-2-((2S,3R)-2-((S)-2-((S)-1-((S)-5-guanidino-2-((S)-5-guanidino-2-(methylamino)pentanamido)pentanoyl)pyrrolidine-2-carboxamido)-3-(4-hydroxyphenyl)propanamido)-3-methylpentanamido)-4-methylpentanoic acid
   Show/Hide
C39H66N12O8
 1
1
EC50 = 0.853 nM
   TI
   LI
   LO
   TS
CP0150134
(S)-2-{(2S,3R)-2-[(S)-2-({(S)-1-[(S)-2-((S)-2-Amino-5-guanidino-pentanoylamino)-5-guanidino-pentanoyl]-pyrrolidine-2-carbonyl}-amino)-3-(4-hydroxy-phenyl)-propionylamino]-3-methyl-pentanoylamino}-4-methyl-pentanoic acid
   Show/Hide
C38H64N12O8
 1
1
EC50 = 1 nM
   TI
   LI
   LO
   TS
CP0424109
(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-5-[[amino-[4-[6-[(2E)-3,3-dimethyl-2-[(2E,4E)-5-(1,3,3-trimethylindol-1-ium-2-yl)penta-2,4-dienylidene]indol-1-yl]hexanoylamino]butylcarbamoylamino]methylidene]amino]pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid;2,2,2-trifluoroacetate;2,2,2-trifluoroacetic acid
   Show/Hide
C81H113F9N16O16
 2
1
EC50 = 1.023 nM
   TI
   LI
   LO
   TS
2
Ki = 4.169 nM
   TI
   LI
   LO
   TS
CP0405472
(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid
   Show/Hide
C38H64N12O8
 3
1
EC50 = 1.202 nM
   TI
   LI
   LO
   TS
2
Ki = 0.1288 nM
   TI
   LI
   LO
   TS
3
Ki = 0.33 nM
   TI
   LI
   LO
   TS
CP0090597
(S)-2-((2S,3R)-2-((S)-2-((S)-1-((S)-5-guanidino-2-(5-guanidinopentanamido)pentanoyl)pyrrolidine-2-carboxamido)-3-(4-hydroxyphenyl)propanamido)-3-methylpentanamido)-4-methylpentanoic acid
   Show/Hide
C38H63N11O8
 1
1
EC50 = 1.85 nM
   TI
   LI
   LO
   TS
CP0223316
(S)-2-((2S,3R)-2-((S)-2-((S)-1-((S)-2-((S)-2-acetamido-5-guanidinopentanamido)-5-guanidinopentanoyl)pyrrolidine-2-carboxamido)-3-(4-hydroxyphenyl)propanamido)-3-methylpentanamido)-4-methylpentanoic acid
   Show/Hide
C40H66N12O9
 1
1
EC50 = 1.89 nM
   TI
   LI
   LO
   TS
CP0064604
(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-4-amino-2-[[(2S)-4-carboxy-2-[[(2S)-3-(4-hydroxyphenyl)-2-[[(2S)-4-methyl-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]amino]propanoyl]amino]butanoyl]amino]-4-oxobutanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid
   Show/Hide
C78H121N21O20
 3
1
EC50 = 1.98 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.2 nM
   TI
   LI
   LO
   TS
3
IC50 = 0.62 nM
   TI
   LI
   LO
   TS
CP0444540
4-[2-[(1E,3E,5E)-5-[1-[6-[4-[[N'-[(4S)-4-amino-5-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S,3S)-1-[[(1S)-1-carboxy-3-methylbutyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-oxopentyl]carbamimidoyl]carbamoylamino]butylamino]-6-oxohexyl]-3,3-dimethyl-5-sulfoindol-2-ylidene]penta-1,3-dienyl]-3,3-dimethylindol-1-ium-1-yl]butane-1-sulfonate;2,2,2-trifluoroacetic acid
   Show/Hide
C82H118F6N16O20S2
 2
1
EC50 = 5.888 nM
   TI
   LI
   LO
   TS
2
Ki = 1.38 nM
   TI
   LI
   LO
   TS
CP0457618
(S)-2-((S)-2-((S)-2-((S)-1-((S)-2-((S)-3,7-diaminoheptanamido)-5-guanidinopentanoyl)pyrrolidine-2-carboxamido)-3-(4-hydroxyphenyl)propanamido)-3,3-dimethylbutanamido)-4-methylpentanoic acid
   Show/Hide
C39H66N10O8
 1
1
EC50 = 6.21 nM
   TI
   LI
   LO
   TS
CP0052233
(S)-2-((S)-2-((S)-2-((S)-1-((S)-2-((S)-3,7-diamino-3-methylheptanamido)-5-guanidinopentanoyl)pyrrolidine-2-carboxamido)-3-(4-hydroxyphenyl)propanamido)-3,3-dimethylbutanamido)-4-methylpentanoic acid
   Show/Hide
C40H68N10O8
 1
1
EC50 = 6.44 nM
   TI
   LI
   LO
   TS
CP0090598
(S)-2-((S)-2-((S)-2-((S)-1-((S)-2-((S)-7-amino-3-azidoheptanamido)-5-guanidinopentanoyl)pyrrolidine-2-carboxamido)-3-(4-hydroxyphenyl)propanamido)-3,3-dimethylbutanamido)-4-methylpentanoic acid
   Show/Hide
C39H64N12O8
 1
1
EC50 = 7.28 nM
   TI
   LI
   LO
   TS
CP0272509
(S)-2-((2S,3R)-2-((S)-2-((S)-1-((S)-2-((S)-2-amino-5-guanidino-2-methylpentanamido)-5-guanidinopentanoyl)pyrrolidine-2-carboxamido)-3-(4-hydroxyphenyl)propanamido)-3-methylpentanamido)-4-methylpentanoic acid
   Show/Hide
C39H66N12O8
 1
1
EC50 = 7.76 nM
   TI
   LI
   LO
   TS
CP0339683
(S)-2-((S)-2-((S)-2-((S)-1-((S)-2-((S)-7-amino-3-(methylamino)heptanamido)-5-guanidinopentanoyl)pyrrolidine-2-carboxamido)-3-(4-hydroxyphenyl)propanamido)-3,3-dimethylbutanamido)-4-methylpentanoic acid
   Show/Hide
C40H68N10O8
 1
1
EC50 = 7.96 nM
   TI
   LI
   LO
   TS
CP0344903
(S)-2-((S)-2-((S)-2-((S)-1-((S)-2-(7-aminoheptanamido)-5-guanidinopentanoyl)pyrrolidine-2-carboxamido)-3-(4-hydroxyphenyl)propanamido)-3,3-dimethylbutanamido)-4-methylpentanoic acid
   Show/Hide
C39H65N9O8
 1
1
EC50 = 25.8 nM
   TI
   LI
   LO
   TS
CP0137802
(S)-2-((S)-2-((S)-2-((S)-1-((S)-2-((S)-3-acetamido-7-aminoheptanamido)-5-guanidinopentanoyl)pyrrolidine-2-carboxamido)-3-(4-hydroxyphenyl)propanamido)-3,3-dimethylbutanamido)-4-methylpentanoic acid
   Show/Hide
C41H68N10O9
 1
1
EC50 = 57.7 nM
   TI
   LI
   LO
   TS
CP0234378
(S)-2-((S)-2-((S)-2-((S)-1-((S)-6-amino-2-((S)-2-azido-5-guanidinopentanamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(1H-indol-3-yl)propanamido)-3,3-dimethylbutanamido)-4-methylpentanoic acid
   Show/Hide
C40H63N13O7
 1
1
EC50 = 151 nM
   TI
   LI
   LO
   TS
CP0270332
(S)-2-((S)-2-((S)-2-((S)-1-((S)-6-amino-2-((S)-5-guanidino-2-(methylamino)pentanamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(1H-indol-3-yl)propanamido)-3,3-dimethylbutanamido)-4-methylpentanoic acid
   Show/Hide
C41H67N11O7
 1
1
EC50 = 200 nM
   TI
   LI
   LO
   TS
CP0042645
(S)-2-((S)-2-((S)-2-((S)-1-((S)-6-amino-2-((S)-2-amino-5-guanidinopentanamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(1H-indol-3-yl)propanamido)-3,3-dimethylbutanamido)-4-methylpentanoic acid
   Show/Hide
C40H65N11O7
 1
1
EC50 = 217 nM
   TI
   LI
   LO
   TS
CP0157890
(S)-2-((S)-2-((S)-2-((S)-1-((S)-2-((S)-2-acetamido-5-guanidinopentanamido)-6-aminohexanoyl)pyrrolidine-2-carboxamido)-3-(1H-indol-3-yl)propanamido)-3,3-dimethylbutanamido)-4-methylpentanoic acid
   Show/Hide
C42H67N11O8
 1
1
EC50 = 764 nM
   TI
   LI
   LO
   TS
CP0333896
(S)-2-((S)-2-((S)-2-((S)-1-((S)-6-amino-2-(5-guanidinopentanamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(1H-indol-3-yl)propanamido)-3,3-dimethylbutanamido)-4-methylpentanoic acid
   Show/Hide
C40H64N10O7
 1
1
EC50 = 783 nM
   TI
   LI
   LO
   TS
CP0234442
(S)-2-((S)-2-((S)-2-((S)-1-((S)-6-amino-2-((S)-2-amino-5-guanidino-2-methylpentanamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(1H-indol-3-yl)propanamido)-3,3-dimethylbutanamido)-4-methylpentanoic acid
   Show/Hide
C41H67N11O7
 1
1
EC50 = 1860 nM
   TI
   LI
   LO
   TS
CP0404157
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-3-[4-(aminomethyl)cyclohexyl]-2-[[2-[2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-2-(1-carbamimidoylpiperidin-4-yl)acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,3-dimethylbutanoyl]amino]-4-methylpentanoic acid
   Show/Hide
C69H112N18O19
 1
1
IC50 = 0.3 nM
   TI
   LI
   LO
   TS
CP0498794
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[2-[2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetyl]amino]-2-piperidin-4-ylacetyl]pyrrolidine-2-carbonyl]amino]-2-(1-carbamimidoylpiperidin-4-yl)acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,3-dimethylbutanoyl]amino]-4-methylpentanoic acid
   Show/Hide
C66H106N18O19
 1
1
IC50 = 0.3 nM
   TI
   LI
   LO
   TS
CP0883489
Demotensin 1
   Show/Hide
C48H85N17O10
 1
1
IC50 = 0.32 nM
   TI
   LI
   LO
   TS
CP0375510
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[2-[2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-carboxybutanoyl]amino]-4-oxobutanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-2-(1-carbamimidoylpiperidin-4-yl)acetyl]amino]-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,3-dimethylbutanoyl]amino]-4,4-dimethylpentanoic acid
   Show/Hide
C84H130N22O26
 1
1
IC50 = 0.4 nM
   TI
   LI
   LO
   TS
CP0475640
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2R)-6-amino-2-[[2-[2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-2-(1-carbamimidoylpiperidin-4-yl)acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,3-dimethylbutanoyl]amino]-4-methylpentanoic acid
   Show/Hide
C65H106N18O19
 1
1
IC50 = 0.4 nM
   TI
   LI
   LO
   TS
CP0506221
(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid
   Show/Hide
C52H85N15O17
 1
1
IC50 = 0.4 nM
   TI
   LI
   LO
   TS
CP0941093
DTPA-DLys-Pro-Arg-Phe(4-Gu)-Pro-Tyr-Ile-Leu-OH
   Show/Hide
C66H102N18O19
 1
1
IC50 = 0.4 nM
   TI
   LI
   LO
   TS
CP0376388
(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[6-amino-2-[[2-[[3-(2-aminoethylamino)-2-[(2-aminoethylamino)methyl]propanoyl]amino]acetyl]amino]hexyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid
   Show/Hide
C48H87N15O9
 1
1
IC50 = 0.41 nM
   TI
   LI
   LO
   TS
CP0874375
alpha-FITC-Gly(Pip)-Pro-Gly(PipAm)-Arg-Pro-Tyr-tBuGly-Leu-OH
   Show/Hide
C75H102N16O15S
 1
1
IC50 = 0.5 nM
   TI
   LI
   LO
   TS
CP0920317
DTPA-DLys-Pro-Arg-Phe(4-Gu)-Arg-Pro-Tyr-Ile-Leu-OH
   Show/Hide
C67H104N18O19
 1
1
IC50 = 0.5 nM
   TI
   LI
   LO
   TS
CP0425317
(4S)-5-[[(2S)-4-amino-1-[[(2S)-6-amino-1-[(2S)-2-[[(1S)-1-(1-carbamimidoylpiperidin-4-yl)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-cyclohexylethyl]amino]-3,3-dimethyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-[[(2S)-2-[[2-[2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-oxopentanoic acid
   Show/Hide
C86H132N22O26
 1
1
IC50 = 0.6 nM
   TI
   LI
   LO
   TS
CP0918470
epsilon-FITC-DLys-Pro-Gly(PipAm)-Arg-Pro-Tyr-Ile-Leu-OH
   Show/Hide
C74H100N16O15S
 1
1
IC50 = 0.6 nM
   TI
   LI
   LO
   TS
CP0943229
DTPA-DLys-Pro-Arg-Gly(PipAm)-Arg-Pro-DTyr-tBuGly-Leu-OH
   Show/Hide
C65H106N18O19
 1
1
IC50 = 0.6 nM
   TI
   LI
   LO
   TS
CP0058950
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[2-[[2-[[3-(2-aminoethylamino)-2-[(2-aminoethylamino)methyl]propanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,3-dimethylbutanoyl]amino]-4-methylpentanoic acid
   Show/Hide
C48H87N17O9
 1
1
IC50 = 0.85 nM
   TI
   LI
   LO
   TS
CP0932046
alpha-FITC-DLys-Pro-Gly(PipAm)-Arg-Pro-Tyr-Ile-Leu-OH
   Show/Hide
C74H100N16O15S
 1
1
IC50 = 1.2 nM
   TI
   LI
   LO
   TS
CP0524385
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[6-amino-2-[[2-[[3-(2-aminoethylamino)-2-[(2-aminoethylamino)methyl]propanoyl]amino]acetyl]amino]hexyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,3-dimethylbutanoyl]amino]-4-methylpentanoic acid
   Show/Hide
C48H87N15O9
 1
1
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
CP0531954
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[[(2S)-6-amino-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[2-[2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-carboxybutanoyl]amino]-4-oxobutanoyl]amino]hexanoyl]carbamoyl]pyrrolidine-2-carbonyl]amino]-2-(1-carbamimidoylpiperidin-4-yl)acetyl]amino]-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,3-dimethylbutanoyl]amino]-4-methylpentanoic acid
   Show/Hide
C84H129N23O27
 1
1
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
CP0518133
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2R)-6-amino-2-[[2-[2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-(1-carbamimidoylpiperidin-4-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,3-dimethylbutanoyl]amino]-4-methylpentanoic acid
   Show/Hide
C66H108N18O19
 1
1
IC50 = 2.5 nM
   TI
   LI
   LO
   TS
CP0935313
alpha,epsilon-Bis(FITC)-DLys-Pro-Gly(PipAm)-Arg-Pro-Tyr-Ile-Leu-OH
   Show/Hide
C96H114N18O20S2
 1
1
IC50 = 3.4 nM
   TI
   LI
   LO
   TS
CP0503506
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2R)-6-amino-2-[[2-[2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-4-(1-carbamimidoylpiperidin-4-yl)butanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,3-dimethylbutanoyl]amino]-4-methylpentanoic acid
   Show/Hide
C67H110N18O19
 1
1
IC50 = 6.3 nM
   TI
   LI
   LO
   TS
CP0869542
DTPA-DLys-Pro-Arg-Aba(Apy)-Arg-Pro-Tyr-Ile-Leu-OH
   Show/Hide
C65H102N18O19
 1
1
IC50 = 10.2 nM
   TI
   LI
   LO
   TS
CP0532381
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2R)-6-amino-2-[[2-[2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetyl]amino]hexanoyl]azetidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-2-(1-carbamimidoylpiperidin-4-yl)acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,3-dimethylbutanoyl]amino]-4-methylpentanoic acid
   Show/Hide
C70H116N22O20
 1
1
IC50 = 11.5 nM
   TI
   LI
   LO
   TS
CP0512411
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[2-[2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-2-(1-carbamimidoylpiperidin-4-yl)acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,3-dimethylbutanoyl]amino]-3-cyclohexylpropanoic acid
   Show/Hide
C68H110N18O19
 1
1
IC50 = 11.87 nM
   TI
   LI
   LO
   TS
CP0498850
2-[2-[[2-[[(2S)-6-amino-1-[(2S)-2-[[(1S)-1-(1-carbamimidoylpiperidin-4-yl)-2-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-3-(4-hydroxyphenyl)-1-[[(2S)-1-[[(2S)-1-methoxy-4,4-dimethyl-1-oxopentan-2-yl]amino]-3,3-dimethyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-2-oxoethyl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-2-oxoethyl]-(carboxymethyl)amino]ethyl-[2-[bis(carboxymethyl)amino]ethyl]amino]acetic acid
   Show/Hide
C67H110N18O19
 1
1
IC50 = 21.7 nM
   TI
   LI
   LO
   TS
CP0932020
DTPA-DLys-Pro-Arg-Phe(4-Gu)-Phe(4-Gu)-Pro-Tyr-Ile-Leu-OH
   Show/Hide
C71H104N18O19
 1
1
IC50 = 22.1 nM
   TI
   LI
   LO
   TS
CP0944532
DTPA-DLys-Pro-Arg-Phe(4-Gu)-Arg-Pro-Tyr-tBuGly-Leu-OH
   Show/Hide
C67H104N18O19
 1
1
IC50 = 24.6 nM
   TI
   LI
   LO
   TS
CP0532044
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[2-[2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-2-(1-carbamimidoylpiperidin-4-yl)acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,3-dimethylbutanoyl]amino]-3-cyclopentylpropanoic acid
   Show/Hide
C67H108N18O19
 1
1
IC50 = 42.4 nM
   TI
   LI
   LO
   TS
CP0859328
DTPA-DLys-Pro-Arg-Gly(PipAm)-Gly(Pip)-Pro-Tyr-tBuGly-Leu-OH
   Show/Hide
C66H106N16O19
 1
1
IC50 = 59.6 nM
   TI
   LI
   LO
   TS
CP0935328
DTPA-DLys-Pro-Arg-Gly(PipAm)-Arg-Pro-mTyr-tBuGly-Leu-OH
   Show/Hide
C65H106N18O19
 1
1
IC50 = 106 nM
   TI
   LI
   LO
   TS
CP0509614
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2R)-6-amino-2-[[2-[2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-2-(1-carbamimidoylpiperidin-4-yl)acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]azetidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,3-dimethylbutanoyl]amino]-4-methylpentanoic acid
   Show/Hide
C70H116N22O20
 1
1
IC50 = 113 nM
   TI
   LI
   LO
   TS
CP0494959
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[2-[2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetyl]amino]-3-(1-carbamimidoylpiperidin-4-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-2-(1-carbamimidoylpiperidin-4-yl)acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,3-dimethylbutanoyl]amino]-4-methylpentanoic acid
   Show/Hide
C68H110N20O19
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0578216
(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-(diaminomethylideneamino)-2-(methylamino)pentanoyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid;2,2,2-trifluoroacetic acid
   Show/Hide
C45H69F9N12O14
 1
1
Ki = 0.223 nM
   TI
   LI
   LO
   TS
CP0560057
(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]-methylamino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid;2,2,2-trifluoroacetic acid
   Show/Hide
C45H69F9N12O14
 1
1
Ki = 0.29 nM
   TI
   LI
   LO
   TS
CP0424111
(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-5-[[amino-[2-[2-[2-[4-[(1E,3E)-4-[4-(dimethylamino)phenyl]buta-1,3-dienyl]-2,6-dimethylpyridin-1-ium-1-yl]ethoxy]ethoxy]ethylcarbamoylamino]methylidene]amino]pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid;2,2,2-trifluoroacetate;2,2,2-trifluoroacetic acid
   Show/Hide
C72H101F12N15O19
 1
1
Ki = 0.7586 nM
   TI
   LI
   LO
   TS
CP0547522
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-(diaminomethylideneamino)-2-(methylamino)pentanoyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,3-dimethylbutanoyl]amino]-4-methylpentanoic acid;2,2,2-trifluoroacetic acid
   Show/Hide
C45H69F9N12O14
 1
1
Ki = 0.88 nM
   TI
   LI
   LO
   TS
CP0484341
(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-(diaminomethylideneamino)-2-(propanoylamino)pentanoyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid;2,2,2-trifluoroacetic acid
   Show/Hide
C45H70F6N12O13
 1
1
Ki = 1 nM
   TI
   LI
   LO
   TS
CP0576156
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,3-dimethylbutanoyl]amino]-4-methylpentanoic acid;2,2,2-trifluoroacetic acid
   Show/Hide
C44H67F9N12O14
 1
1
Ki = 1.17 nM
   TI
   LI
   LO
   TS
CP0443925
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]-methylamino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,3-dimethylbutanoyl]amino]-4-methylpentanoic acid;2,2,2-trifluoroacetic acid
   Show/Hide
C45H69F9N12O14
 1
1
Ki = 1.6 nM
   TI
   LI
   LO
   TS
CP0444541
4-[2-[(1E,3E,5E)-5-[1-[6-[2-[2-[2-[[N'-[(4S)-4-amino-5-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S,3S)-1-[[(1S)-1-carboxy-3-methylbutyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-oxopentyl]carbamimidoyl]carbamoylamino]ethoxy]ethoxy]ethylamino]-6-oxohexyl]-3,3-dimethyl-5-sulfoindol-2-ylidene]penta-1,3-dienyl]-3,3-dimethylindol-1-ium-1-yl]butane-1-sulfonate;2,2,2-trifluoroacetic acid
   Show/Hide
C84H122F6N16O22S2
 1
1
Ki = 1.995 nM
   TI
   LI
   LO
   TS
CP0444542
(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-5-[[amino-[2-[2-[2-[6-[(2E)-3,3-dimethyl-2-[(2E,4E)-5-(1,3,3-trimethylindol-1-ium-2-yl)penta-2,4-dienylidene]indol-1-yl]hexanoylamino]ethoxy]ethoxy]ethylcarbamoylamino]methylidene]amino]pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid;2,2,2-trifluoroacetate;2,2,2-trifluoroacetic acid
   Show/Hide
C85H118F12N16O20
 1
1
Ki = 2.188 nM
   TI
   LI
   LO
   TS
CP0476569
4-[(2Z)-2-[(2E,4E)-5-[1-[6-[2-[2-[2-[[N'-[(4S)-4-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-[(2S)-2-[[(2S)-1-[[(2S,3S)-1-[[(1S)-1-carboxy-3-methylbutyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-oxopentyl]carbamimidoyl]carbamoylamino]ethoxy]ethoxy]ethylamino]-6-oxohexyl]-3,3-dimethylindol-1-ium-2-yl]penta-2,4-dienylidene]-3,3-dimethylindol-1-yl]butane-1-sulfonate;2,2,2-trifluoroacetic acid
   Show/Hide
C86H123F9N16O21S
 1
1
Ki = 2.692 nM
   TI
   LI
   LO
   TS
CP0424107
4-[2-[(1E,3E,5E)-5-[1-[6-[2-[2-[2-[[N'-[(4S)-4-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-[(2S)-2-[[(2S)-1-[[(2S,3S)-1-[[(1S)-1-carboxy-3-methylbutyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-oxopentyl]carbamimidoyl]carbamoylamino]ethoxy]ethoxy]ethylamino]-6-oxohexyl]-3,3-dimethyl-5-sulfoindol-2-ylidene]penta-1,3-dienyl]-3,3-dimethylindol-1-ium-1-yl]butane-1-sulfonate;2,2,2-trifluoroacetic acid
   Show/Hide
C84H122F6N16O22S2
 1
1
Ki = 3.548 nM
   TI
   LI
   LO
   TS
CP0424105
4-[(2Z)-2-[(2E,4E)-5-[1-[6-[2-[2-[2-[[N'-[(4S)-4-amino-5-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S,3S)-1-[[(1S)-1-carboxy-3-methylbutyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-oxopentyl]carbamimidoyl]carbamoylamino]ethoxy]ethoxy]ethylamino]-6-oxohexyl]-3,3-dimethylindol-1-ium-2-yl]penta-2,4-dienylidene]-3,3-dimethylindol-1-yl]butane-1-sulfonate;2,2,2-trifluoroacetic acid
   Show/Hide
C86H123F9N16O21S
 1
1
Ki = 4.266 nM
   TI
   LI
   LO
   TS
CP0484342
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-(diaminomethylideneamino)-2-(propanoylamino)pentanoyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,3-dimethylbutanoyl]amino]-4-methylpentanoic acid;2,2,2-trifluoroacetic acid
   Show/Hide
C45H70F6N12O13
 1
1
Ki = 18 nM
   TI
   LI
   LO
   TS
CP0416236
(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]-methylamino]-3-methylpentanoyl]amino]-4-methylpentanoic acid;2,2,2-trifluoroacetic acid
   Show/Hide
C45H69F9N12O14
 1
1
Ki = 60 nM
   TI
   LI
   LO
   TS
CP0567471
(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]-methylamino]-4-methylpentanoic acid;2,2,2-trifluoroacetic acid
   Show/Hide
C45H69F9N12O14
 1
1
Ki = 880 nM
   TI
   LI
   LO
   TS
CP0484208
(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]-methylamino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid;2,2,2-trifluoroacetic acid
   Show/Hide
C45H69F9N12O14
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS