Brief Information of the Cell Line and Protein
Cell Line ID: CL000309 , NCTC clone 929
Synonyms
NCTC 929
NCTC-929
NCTC929
NCTC-929L
L cell
L cells
L-cell
L-cells
L cell line
L
Strain L-929
L-929
L 929
L929
L929(NCTC)
Clone 929
Earles's cells
Earle's L cells
Category Spontaneously immortalized cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0462
Protein ID: PT02347 , Tumor necrosis factor
Gene Name TNF
Organism Homo sapiens, Human
Protein Classification Secreted protein
Uniprot ID P01375
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000309  Protein ID: PT02347
 
Compound ID Compound Name Compound Formula
CP0123474
6,7-dimethyl-3-[[methyl-[2-[methyl-[[1-[3-(trifluoromethyl)phenyl]indol-3-yl]methyl]amino]ethyl]amino]methyl]chromen-4-one
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C32H32F3N3O2
 1
1
IC50 = 5000 nM
   TI
   LI
   LO
   TS
CP0107154
3-[4-[1-(3-aminophenyl)indole-3-carbonyl]piperazine-1-carbonyl]chromen-4-one
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C29H24N4O4
 1
1
IC50 = 10000 nM
   TI
   LI
   LO
   TS
CP0127245
3-[4-[[1-[3-(trifluoromethyl)phenyl]indol-3-yl]methyl]piperazine-1-carbonyl]chromen-4-one
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C30H24F3N3O3
 1
1
IC50 = 10000 nM
   TI
   LI
   LO
   TS
CP0205832
6,7-dimethyl-3-[[4-[[1-[3-(trifluoromethyl)phenyl]indol-3-yl]methyl]piperazin-1-yl]methyl]chromen-4-one
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C32H30F3N3O2
 1
1
IC50 = 10000 nM
   TI
   LI
   LO
   TS
CP0107157
phenyl-[4-[[1-[3-(trifluoromethyl)phenyl]indol-3-yl]methyl]piperazin-1-yl]methanone
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C27H24F3N3O
 1
1
IC50 = 15000 nM
   TI
   LI
   LO
   TS
CP0363900
3-[4-[1-(benzenesulfonyl)indole-3-carbonyl]piperazine-1-carbonyl]chromen-4-one
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C29H23N3O6S
 1
1
IC50 = 15000 nM
   TI
   LI
   LO
   TS
CP0657649
3-(4-(5-Nitro-1-(3-nitrophenyl)-1H-indole-3-carbonyl)piperazine-1-carbonyl)-4H-chromen-4-one
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C29H21N5O8
 1
1
IC50 = 15000 nM
   TI
   LI
   LO
   TS
CP0141388
N-methyl-N-[2-[methyl-(4-oxochromene-3-carbonyl)amino]ethyl]-1-(3-nitrophenyl)sulfonylindole-3-carboxamide
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C29H24N4O8S
 1
1
IC50 = 20000 nM
   TI
   LI
   LO
   TS
CP0649297
N-methyl-1-(3-(trifluoromethyl)phenyl)-N-(2-(N,6,7-trimethyl-4-oxo-4H-chromene-3-carboxamido)ethyl)-1H-indole-3-carboxamide
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C32H28F3N3O4
 1
1
IC50 = 20000 nM
   TI
   LI
   LO
   TS
CP0649299
3-(4-(1-(3-Nitrophenylsulfonyl)-1H-indole-3-carbonyl)piperazine-1-carbonyl)-4H-chromen-4-one
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C29H22N4O8S
 1
1
IC50 = 20000 nM
   TI
   LI
   LO
   TS
CP0649301
3-(4-(1-(3-Aminophenylsulfonyl)-1H-indole-3-carbonyl)piperazine-1-carbonyl)-4H-chromen-4-one
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C29H24N4O6S
 1
1
IC50 = 20000 nM
   TI
   LI
   LO
   TS
CP0734904
Naphthalen-2-yl-(4-((1-(3-(trifluoromethyl)phenyl)-1H-indol-3-yl)methyl)piperazin-1-yl)methanone
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C31H26F3N3O
 1
1
IC50 = 20000 nM
   TI
   LI
   LO
   TS
CP0755021
N-(3-(4-oxo-4H-chromene-3-carboxamido)propyl)-1-(phenylsulfonyl)-1H-indole-3-carboxamide
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C28H23N3O6S
 1
1
IC50 = 20000 nM
   TI
   LI
   LO
   TS
CP0141389
1-(3-aminophenyl)sulfonyl-N-methyl-N-[2-[methyl-(4-oxochromene-3-carbonyl)amino]ethyl]indole-3-carboxamide
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C29H26N4O6S
 1
1
IC50 = 25000 nM
   TI
   LI
   LO
   TS
CP0363899
6-methyl-3-[[4-[[1-[3-(trifluoromethyl)phenyl]indol-3-yl]methyl]piperazin-1-yl]methyl]chromen-4-one
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C31H28F3N3O2
 1
1
IC50 = 30000 nM
   TI
   LI
   LO
   TS
CP0839493
6-Methyl-3-((methyl(2-(methyl((1-(3-trifluoromethyl)phenyl)-1H-indol-3-yl)methyl)amino)ethyl)amino)methyl)-4H-chromen-4-one
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C31H30F3N3O2
 1
1
IC50 = 30000 nM
   TI
   LI
   LO
   TS
CP0107156
3-[4-[5-amino-1-(3-aminophenyl)indole-3-carbonyl]piperazine-1-carbonyl]chromen-4-one
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C29H25N5O4
 1
1
IC50 = 40000 nM
   TI
   LI
   LO
   TS
CP0041754
1-(benzenesulfonyl)-N-methyl-N-[2-[methyl-(4-oxochromene-3-carbonyl)amino]ethyl]indole-3-carboxamide
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C29H25N3O6S
 1
1
IC50 > 60000 nM
   TI
   LI
   LO
   TS