Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6,7-dimethyl-3-[[methyl-[2-[methyl-[[1-[3-(trifluoromethyl)phenyl]indol-3-yl]methyl]amino]ethyl]amino]methyl]chromen-4-one
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 PubChem ID
CID: 5327044
SID: 16738441
Canonical SMILES
CN(CCN(C)Cc1coc2cc(C)c(C)cc2c1=O)Cc1cn(-c2cccc(c2)C(F)(F)F)c2ccccc12
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Compound Formula C32H32F3N3O2
Compound Structure
Protein Name
 Protein Info 
Tumor necrosis factor
Protein Classification
Secreted protein
Uniprot ID
P01375
Gene Name
TNF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000309 NCTC clone 929
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 5000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1200 nM
2 IC50 = 1300 nM
3 IC50 = 5000 nM
4 IC50 = 22000 nM
5 Kd = 3.81 nM
6 Kd = 5360 nM
7 Kd = 5700 nM
8 Kd = 5750 nM
9 Kd = 6180 nM
10 Kd = 7340 nM
11 Kd = 7510 nM
12 Kd = 8300 nM
13 Kd = 8440 nM
14 Kd = 9770 nM
15 Kd = 11810 nM
16 Kd = 13000 nM