Compound ID |
Compound Name |
Compound Formula |
CP0847317
|
2-{(2R,4aR,5R,6R,7aS)-6-hydroxy-5-[(1E,3R)-3-hydroxy-4-phenoxy-1-buten-1-yl]octahydrocyclopenta[b]pyran-2-yl}-1,3-thiazole-4-carboxylic acid
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|
C22H25NO6S
|
1
|
1 |
EC50 = 32 nM
|
|
|
CP0055947
|
(15S)-prostaglandin E2
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|
C20H32O5
|
1
|
1 |
EC50 = 250 nM
|
|
|
CP0862926
|
2-{(2R,4aR,5R,6R,7aS)-6-hydroxy-5-[(1E)-4-phenoxy-1-buten-1-yl]octahydrocyclopenta[b]pyran-2-yl}-1,3-thiazole-4-carboxylic acid
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|
C22H25NO5S
|
1
|
1 |
EC50 = 380 nM
|
|
|
CP0847322
|
2-{(2R,4aR,5R,6R,7aS)-6-hydroxy-5-[(1E)-5-phenoxy-1-penten-1-yl]octahydrocyclopenta[b]pyran-2-yl}-1,3-thiazole-4-carboxylic acid
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|
C23H27NO5S
|
1
|
1 |
EC50 = 8500 nM
|
|
|
CP0391092
|
2-[(2R,4aR,5S,6R,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-oxazole-4-carboxylic acid
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|
C20H22ClNO6
|
1
|
1 |
EC50 > 10000 nM
|
|
|
CP0391098
|
4-[(2R,4aR,5S,6R,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]thiophene-2-carboxylic acid
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|
C21H23ClO5S
|
1
|
1 |
EC50 > 10000 nM
|
|
|
CP0401698
|
2-[(2R,4aR,5S,6S,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-methoxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
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|
C21H24ClNO5S
|
1
|
1 |
EC50 > 10000 nM
|
|
|
CP0401699
|
2-[(2R,4aR,5S,6R,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C20H22ClNO5S
|
1
|
1 |
EC50 > 10000 nM
|
|
|
CP0401700
|
2-[(2R,4aR,5S,6S,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C20H22ClNO5S
|
1
|
1 |
EC50 > 10000 nM
|
|
|
CP0401702
|
2-[(2R,4aR,5S,6S,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-fluoro-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C20H21ClFNO4S
|
1
|
1 |
EC50 > 10000 nM
|
|
|
CP0407410
|
4-[(2R,4aR,5S,6R,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]furan-2-carboxylic acid
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|
C21H23ClO6
|
1
|
1 |
EC50 > 10000 nM
|
|
|
CP0434444
|
5-[(2R,4aR,5S,6R,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]furan-2-carboxylic acid
Show/Hide
|
C21H23ClO6
|
1
|
1 |
EC50 > 10000 nM
|
|
|
CP0380278
|
2-[(2R,4aR,5S,6R,7aS)-6-hydroxy-5-(phenoxymethyl)-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C19H21NO5S
|
1
|
1 |
EC50 > 10000 nM
|
|
|
CP0847318
|
2-{(2R,4aR,5R,6R,7aS)-6-hydroxy-5-[(1E)-3-phenoxy-1-propen-1-yl]octahydrocyclopenta[b]pyran-2-yl}-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C21H23NO5S
|
1
|
1 |
EC50 > 10000 nM
|
|
|
CP0847320
|
2-[(2R,4aR,5R,6R,7aS)-6-hydroxy-5-(2-phenoxyethyl)octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C20H23NO5S
|
1
|
1 |
EC50 > 10000 nM
|
|
|
CP0870958
|
2-[(2R,4aR,5R,6R,7aS)-6-hydroxy-5-(3-phenoxypropyl)octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
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|
C21H25NO5S
|
1
|
1 |
EC50 > 10000 nM
|
|
|
CP0573893
|
6-bromo-N-[2-fluoro-4-(2H-tetrazol-5-yl)phenyl]-3-methyl-2-phenylquinoline-4-carboxamide
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|
C24H16BrFN6O
|
1
|
1 |
IC50 = 5.2 nM
|
|
|
CP0566005
|
3-Fluoro-4-{[(6-iodo-3-methyl-2-phenylquinolin-4-yl)carbonyl]amino}benzoic acid
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|
C24H16FIN2O3
|
1
|
1 |
IC50 = 6 nM
|
|
|
CP0515075
|
US11149018, Example 276
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|
C26H27BrClN3O3
|
1
|
1 |
IC50 = 7.2 nM
|
|
|
CP0272414
|
US11149018, Example 34
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|
C26H27BrClN3O3
|
1
|
1 |
IC50 = 11 nM
|
|
|
CP0537756
|
4-[(7-bromo-2-methyl-3-phenylnaphthalene-1-carbonyl)amino]-3-fluorobenzoic acid
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|
C25H17BrFNO3
|
1
|
1 |
IC50 = 13 nM
|
|
|
CP0566006
|
4-{[(6-Bromo-3-chloro-2-phenylquinolin-4-yl)carbonyl]amino}-3-fluorobenzoic acid
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|
C23H13BrClFN2O3
|
1
|
1 |
IC50 = 17 nM
|
|
|
CP0578279
|
4-[(6-bromo-3-methyl-2-phenylquinolin-4-yl)methylamino]-3-fluorobenzoic acid
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|
C24H18BrFN2O2
|
1
|
1 |
IC50 = 25 nM
|
|
|
CP0548134
|
4-{[(6-Bromo-3-cyclopropyl-2-phenylquinolin-4-yl)carbonyl]amino}-3-fluorobenzoic acid
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|
C26H18BrFN2O3
|
1
|
1 |
IC50 = 27 nM
|
|
|
CP0565043
|
4-{[(6-Bromo-3-methyl-2-phenylquinolin-4-yl)carbonyl]amino}-3-fluorobenzoic acid
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|
C24H16BrFN2O3
|
1
|
1 |
IC50 = 27 nM
|
|
|
CP0568628
|
4-[(6-bromo-3-methyl-1-oxo-2-phenylisoquinoline-4-carbonyl)amino]-3-fluorobenzoic acid
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|
C24H16BrFN2O4
|
1
|
1 |
IC50 = 40 nM
|
|
|
CP0572524
|
4-{[(6-Bromo-3-methyl-2-phenylquinolin-4-yl)carbonyl]amino}bicyclo[2.2.2]octane-1-carboxylic acid
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|
C26H25BrN2O3
|
1
|
1 |
IC50 = 68 nM
|
|
|
CP0571433
|
3-Fluoro-4-({[3-methyl-2-phenyl-6-(trifluoromethyl)quinolin-4-yl]carbonyl}amino)benzoic acid
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|
C25H16F4N2O3
|
1
|
1 |
IC50 = 93 nM
|
|
|
CP0548202
|
6-Bromo-N-(4-carbamoyl-2-fluorophenyl)-3-methyl-2-phenylquinoline-4-carboxamide
Show/Hide
|
C24H17BrFN3O2
|
1
|
1 |
IC50 = 100 nM
|
|
|
CP0537758
|
(+/−)-5-({[6-Bromo-2-(3,3-difluoroazetidin-1-yl)-3-methylquinolin-4-yl]carbonyl}amino)-4-(2-chlorophenyl)pentanoic acid (Racemate)
Show/Hide
|
C25H23BrClF2N3O3
|
1
|
1 |
IC50 = 120 nM
|
|
|
CP0539216
|
4-{[(6-Bromo-3-methyl-1-oxido-2-phenylquinolin-4-yl)carbonyl]amino}-3-fluorobenzoic acid
Show/Hide
|
C24H16BrFN2O4
|
1
|
1 |
IC50 = 120 nM
|
|
|
CP0558306
|
4-{[(6-tert-Butyl-3-methyl-2-phenylquinolin-4-yl)carbonyl]amino}-3-fluorobenzoic acid
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|
C28H25FN2O3
|
1
|
1 |
IC50 = 130 nM
|
|
|
CP0568627
|
4-{[(6-Bromo-3-methyl-2-phenylquinolin-4-yl)carbonyl]amino}benzoic acid
Show/Hide
|
C24H17BrN2O3
|
1
|
1 |
IC50 = 150 nM
|
|
|
CP0537754
|
6-bromo-3-methyl-2-phenyl-N-(2-pyridin-2-ylpropyl)quinoline-4-carboxamide
Show/Hide
|
C25H22BrN3O
|
1
|
1 |
IC50 = 190 nM
|
|
|
CP0545859
|
4-[(6-bromo-3-methyl-2-phenylquinoline-4-carbonyl)amino]-3-(3-methoxyphenyl)butanoic acid
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|
C28H25BrN2O4
|
1
|
1 |
IC50 = 190 nM
|
|
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CP0548201
|
4-{[(6-Chloro-3-methyl-2-phenylquinolin-4-yl)carbonyl]amino}-3-fluorobenzoic acid
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|
C24H16ClFN2O3
|
1
|
1 |
IC50 = 200 nM
|
|
|
CP0558304
|
6-bromo-3-methyl-2-phenyl-N-(2-pyridin-2-ylethyl)quinoline-4-carboxamide
Show/Hide
|
C24H20BrN3O
|
1
|
1 |
IC50 = 200 nM
|
|
|
CP0558305
|
4-[(6-bromo-3-methyl-2-phenylquinolin-4-yl)methoxy]-3-fluorobenzoic acid
Show/Hide
|
C24H17BrFNO3
|
1
|
1 |
IC50 = 250 nM
|
|
|
CP0537755
|
6-bromo-3-methyl-2-phenyl-N-(1-pyridin-2-ylpropan-2-yl)quinoline-4-carboxamide
Show/Hide
|
C25H22BrN3O
|
1
|
1 |
IC50 = 500 nM
|
|
|
CP0565171
|
4-[(6-bromo-3-methyl-2-phenylquinoline-4-carbonyl)amino]-3-(4-methoxyphenyl)butanoic acid
Show/Hide
|
C28H25BrN2O4
|
1
|
1 |
IC50 = 1100 nM
|
|
|
CP0471861
|
6-bromo-3-methyl-N-(2-pyridin-3-ylethyl)-2-thiophen-2-ylquinoline-4-carboxamide
Show/Hide
|
C22H18BrN3OS
|
1
|
1 |
IC50 = 1800 nM
|
|
|
CP0566004
|
6-bromo-3-methyl-2-phenyl-N-(2-pyridin-3-ylethyl)quinoline-4-carboxamide
Show/Hide
|
C24H20BrN3O
|
1
|
1 |
IC50 = 3400 nM
|
|
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CP0543684
|
6-bromo-N,3-dimethyl-2-phenyl-N-(2-pyridin-2-ylethyl)quinoline-4-carboxamide
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|
C25H22BrN3O
|
1
|
1 |
IC50 = 15000 nM
|
|
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