Brief Information of the Compound and Protein
Compound Name
(+/−)-5-({[6-Bromo-2-(3,3-difluoroazetidin-1-yl)-3-methylquinolin-4-yl]carbonyl}amino)-4-(2-chlorophenyl)pentanoic acid (Racemate)
    Show/Hide
PubChem ID
CID: 142451618
Canonical SMILES
Cc1c(nc2ccc(Br)cc2c1C(=O)NCC(CCC(O)=O)c1ccccc1Cl)N1CC(F)(F)C1
    Show/Hide
Compound Formula C25H23BrClF2N3O3
Compound Structure
Protein Name
Prostaglandin F2-alpha receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Prostanoid receptor
Uniprot ID
P43088
Gene Name
PTGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000064 Chem-1 Rattus norvegicus (Rat)  1
1
IC50 = 120 nM
   TI
   LI
   LO
   TS