General Information of the Compound
Compound ID
CP0568628
Compound Name
4-[(6-bromo-3-methyl-1-oxo-2-phenylisoquinoline-4-carbonyl)amino]-3-fluorobenzoic acid
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Structure
Formula
C24H16BrFN2O4
Molecular Weight
495.304
Canonical SMILES
Cc1c(C(=O)Nc2ccc(cc2F)C(O)=O)c2cc(Br)ccc2c(=O)n1-c1ccccc1
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InChI
InChI=1S/C24H16BrFN2O4/c1-13-21(22(29)27-20-10-7-14(24(31)32)11-19(20)26)18-12-15(25)8-9-17(18)23(30)28(13)16-5-3-2-4-6-16/h2-12H,1H3,(H,27,29)(H,31,32)
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InChIKey
IYXVIZFMCZGPTG-UHFFFAOYSA-N
Physicochemical Property
logP
5.15122
Rotatable Bonds
4
Heavy Atom Count
32
Polar Areas
88.4
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 130405858
ChEMBL ID
CHEMBL4759438
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01823, Prostaglandin F2-alpha receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000064 Chem-1 Rattus norvegicus (Rat)  1
1
IC50 = 40 nM
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