Brief Information of the Cell Line and Protein
Cell Line ID: CL000370 , SC-3
Category Cancer cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_D3L9
Protein ID: PT01577 , Androgen receptor
Gene Name AR
Organism Mus musculus, Mouse
Protein Classification Transcription factor
Uniprot ID P19091
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000370  Protein ID: PT01577
 
Compound ID Compound Name Compound Formula
CP0104937
(2S)-3-{4-[1-ethyl-1-(4-{[(2R)-2-hydroxy-3,3-dimethylbutyl]oxy}-3-methylphenyl)propyl]-2-methylphenoxy}propane-1,2-diol
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C28H42O5
 1
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
CP0216247
1-(4-{1-[4-(2,3-Dihydroxy-propylamino)-3-methyl-phenyl]-1-ethyl-propyl}-2-methyl-phenoxy)-3,3-dimethyl-butan-2-one
   Show/Hide
C28H41NO4
 1
1
IC50 = 7.6 nM
   TI
   LI
   LO
   TS
CP0216246
3-(4-{1-Ethyl-1-[4-(2-hydroxy-3,3-dimethyl-butoxy)-3-methyl-phenyl]-propyl}-2-methyl-phenylamino)-propane-1,2-diol
   Show/Hide
C28H43NO4
 1
1
IC50 = 9 nM
   TI
   LI
   LO
   TS
CP0162322
(S)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol
   Show/Hide
C28H42O5
 1
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
CP0064103
(R)-3-(4-(3-(4-((R)-2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol
   Show/Hide
C28H42O5
 1
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
CP0092948
(R)-1-(4-(3-(4-(2,3-dihydroxypropoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)-3,3-dimethylbutan-2-one
   Show/Hide
C28H40O5
 1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
CP0134848
LG-190178
   Show/Hide
C28H42O5
 1
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
CP0146330
(S)-1-(4-(3-(4-(2,3-dihydroxypropoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)-3,3-dimethylbutan-2-one
   Show/Hide
C28H40O5
 1
1
IC50 = 32 nM
   TI
   LI
   LO
   TS
CP0105737
(R)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol
   Show/Hide
C28H42O5
 1
1
IC50 = 68 nM
   TI
   LI
   LO
   TS
CP0392397
(2R)-3-[4-[diethyl-[4-[(2S)-2-hydroxy-3,3-dimethylbutoxy]-3-methylphenyl]silyl]-2-methylphenoxy]propane-1,2-diol
   Show/Hide
C27H42O5Si
 1
1
IC50 = 72 nM
   TI
   LI
   LO
   TS
CP0418099
1-[4-[[4-[(2R)-2,3-dihydroxypropoxy]-3-methylphenyl]-diethylsilyl]-2-methylphenoxy]-3,3-dimethylbutan-2-one
   Show/Hide
C27H40O5Si
 1
1
IC50 = 113 nM
   TI
   LI
   LO
   TS
CP0373634
(2S)-3-(4-(3-(4-(2-hydroxy-3,3-dimethyl-6-phenylhexyloxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol
   Show/Hide
C36H50O5
 1
1
IC50 = 130 nM
   TI
   LI
   LO
   TS
CP0040191
2-Hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide
   Show/Hide
C11H11F3N2O4
 2
1
IC50 = 370 nM
   TI
   LI
   LO
   TS
2
IC50 = 1400 nM
   TI
   LI
   LO
   TS
CP0146696
Bicalutamide
   Show/Hide
C18H14F4N2O4S
 2
1
IC50 = 670 nM
   TI
   LI
   LO
   TS
2
IC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0408556
N-[4-(4-hydroxyphenoxy)-3-methylphenyl]-3-methoxybenzamide
   Show/Hide
C21H19NO4
 1
1
IC50 = 750 nM
   TI
   LI
   LO
   TS
CP0320240
1-(4-{1-Ethyl-1-[4-(3-hydroxy-3-methyl-butylamino)-3-methyl-phenyl]-propyl}-2-methyl-phenoxy)-3,3-dimethyl-butan-2-one
   Show/Hide
C30H45NO3
 1
1
IC50 = 820 nM
   TI
   LI
   LO
   TS
CP0400163
(2S)-3-(4-(3-(4-(2-hydroxy-3,3-dimethyl-5-phenylpentyloxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol
   Show/Hide
C35H48O5
 1
1
IC50 = 880 nM
   TI
   LI
   LO
   TS
CP0172886
1-[4-[3-[4-[(2-hydroxy-3,3-dimethylbutyl)amino]-3-methylphenyl]pentan-3-yl]-2-methylanilino]-3,3-dimethylbutan-2-ol
   Show/Hide
C31H50N2O2
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0180381
1-[4-[3-[4-[(3,3-dimethyl-2-oxobutyl)amino]-3-methylphenyl]pentan-3-yl]-2-methylanilino]-3,3-dimethylbutan-2-one
   Show/Hide
C31H46N2O2
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0405899
(S)-1-(4-(3-(4-(2,3-dihydroxypropoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)-3,3-dimethyl-5-phenylpentan-2-one
   Show/Hide
C35H46O5
 1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0200347
1-[4-[3-[4-(3,3-dimethyl-2-oxobutoxy)-3-methylphenyl]pentan-3-yl]-2-methylanilino]-3,3-dimethylbutan-2-one
   Show/Hide
C31H45NO3
 1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
CP0373633
(2S)-3-(4-(3-(4-(2-hydroxy-3,3-dimethyl-4-phenylbutoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol
   Show/Hide
C34H46O5
 1
1
IC50 = 1700 nM
   TI
   LI
   LO
   TS
CP0216245
LG190155
   Show/Hide
C31H44O4
 1
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS
CP0435121
N-[4-(4-hydroxyphenoxy)phenyl]-3-methoxybenzamide
   Show/Hide
C20H17NO4
 1
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
CP0461442
N-[4-(4-hydroxyphenoxy)-3,5-dimethylphenyl]-3-methoxybenzamide
   Show/Hide
C22H21NO4
 1
1
IC50 = 2900 nM
   TI
   LI
   LO
   TS
CP0478781
3-(dimethylamino)-N-[4-(4-hydroxyphenoxy)phenyl]benzamide
   Show/Hide
C21H20N2O3
 1
1
IC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0306007
1-[4-[3-(4-hydroxy-3-methylphenyl)pentan-3-yl]-2-methylanilino]-3,3-dimethylbutan-2-one
   Show/Hide
C25H35NO2
 1
1
IC50 = 3500 nM
   TI
   LI
   LO
   TS
CP0540079
N-[2-(4-hydroxyphenoxy)pyrimidin-5-yl]-3-methoxybenzamide
   Show/Hide
C18H15N3O4
 1
1
IC50 = 5900 nM
   TI
   LI
   LO
   TS
CP0438255
4-(dimethylamino)-N-[4-(4-hydroxyphenoxy)phenyl]benzamide
   Show/Hide
C21H20N2O3
 1
1
IC50 = 6700 nM
   TI
   LI
   LO
   TS
CP0170585
4-(4-{1-Ethyl-1-[4-(3-hydroxy-3-methyl-butylamino)-3-methyl-phenyl]-propyl}-2-methyl-phenylamino)-2-methyl-butan-2-ol
   Show/Hide
C29H46N2O2
 1
1
IC50 = 6800 nM
   TI
   LI
   LO
   TS
CP0476803
N-[6-(4-hydroxyphenoxy)pyridin-3-yl]-3-methoxybenzamide
   Show/Hide
C19H16N2O4
 1
1
IC50 = 7200 nM
   TI
   LI
   LO
   TS
CP0478780
N-[4-(4-hydroxyphenoxy)phenyl]pyridine-2-carboxamide
   Show/Hide
C18H14N2O3
 1
1
IC50 = 8700 nM
   TI
   LI
   LO
   TS
CP0438256
2-hydroxy-N-[4-(4-hydroxyphenoxy)phenyl]benzamide
   Show/Hide
C19H15NO4
 1
1
IC50 = 8800 nM
   TI
   LI
   LO
   TS
CP0554497
N-[4-(4-hydroxyphenoxy)phenyl]benzamide
   Show/Hide
C19H15NO3
 1
1
IC50 = 9400 nM
   TI
   LI
   LO
   TS
CP0476804
N-[4-(4-hydroxyphenoxy)phenyl]pyridine-3-carboxamide
   Show/Hide
C18H14N2O3
 1
1
IC50 = 9700 nM
   TI
   LI
   LO
   TS
CP0502679
(S)-1-(4-(3-(4-(2,3-dihydroxypropoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)-3,3-dimethyl-6-phenylhexan-2-one
   Show/Hide
C36H48O5
 1
1
IC50 = 9800 nM
   TI
   LI
   LO
   TS
CP0377245
(2S)-3-(4-(3-(4-(2-hydroxy-3,3-dimethyl-4-(naphthalen-2-yl)butoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol
   Show/Hide
C38H48O5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0377246
(2S)-3-(4-(3-(4-(2-hydroxy-3,3-dimethyl-7-phenylheptyloxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol
   Show/Hide
C37H52O5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0386138
(2S)-3-(4-(3-(4-(1-benzyl-4-hydroxypyrrolidin-3-yloxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol
   Show/Hide
C33H43NO5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0388209
(S)-1-(4-(3-(4-(2,3-dihydroxypropoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)-3,3-dimethyl-4-phenylbutan-2-one
   Show/Hide
C34H44O5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0519900
(2S)-3-[4-[3-[4-[2-(1-adamantyl)-2-hydroxyethoxy]-3-methylphenyl]pentan-3-yl]-2-methylphenoxy]propane-1,2-diol
   Show/Hide
C34H48O5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0379850
N-[4-(4-hydroxyphenoxy)phenyl]-3-nitrobenzamide
   Show/Hide
C19H14N2O5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0424503
N-(4-phenoxyphenyl)benzamide
   Show/Hide
C19H15NO2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0435126
N-[4-(4-hydroxyphenoxy)phenyl]-4-nitrobenzamide
   Show/Hide
C19H14N2O5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0476805
N-[4-(4-hydroxyphenoxy)phenyl]-2-nitrobenzamide
   Show/Hide
C19H14N2O5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0492999
N-[4-(4-hydroxyphenoxy)phenyl]pyridine-4-carboxamide
   Show/Hide
C18H14N2O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0493004
N-[4-(4-hydroxyphenoxy)phenyl]-2-methoxybenzamide
   Show/Hide
C20H17NO4
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0554496
N-[4-(4-hydroxyphenoxy)phenyl]-4-methoxybenzamide
   Show/Hide
C20H17NO4
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0377244
1-(1-adamantyl)-2-[4-[3-[4-[(2S)-2,3-dihydroxypropoxy]-3-methylphenyl]pentan-3-yl]-2-methylphenoxy]ethanone
   Show/Hide
C34H46O5
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0386137
(S)-1-(4-(3-(4-(2,3-dihydroxypropoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)-3,3-dimethyl-4-(naphthalen-2-yl)butan-2-one
   Show/Hide
C38H46O5
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0400164
benzyl (3R,4S)-3-[4-[3-[4-[(2S)-2,3-dihydroxypropoxy]-3-methylphenyl]pentan-3-yl]-2-methylphenoxy]-4-hydroxypyrrolidine-1-carboxylate
   Show/Hide
C34H43NO7
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0519898
(S)-1-(4-(3-(4-(2,3-dihydroxypropoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)-3,3-dimethyl-7-phenylheptan-2-one
   Show/Hide
C37H50O5
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS