Brief Information of the Cell Line and Protein
Cell Line ID: CL000150 , HaCaT
Synonyms
HaCAT
HACAT
Hacat
Category Spontaneously immortalized cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0038
Protein ID: PT01503 , Signal transducer and activator of transcription 3
Gene Name STAT3
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P40763
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000150  Protein ID: PT01503
 
Compound ID Compound Name Compound Formula
CP0015639
(1E,4E)-1,5-Bis-(4-hydroxy-3-methoxy-phenyl)-penta-1,4-dien-3-one
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C19H18O5
 1
1
IC50 = 6000 nM
   TI
   LI
   LO
   TS
CP0115322
(1E,6E)-1,7-bis(3-fluoro-4-hydroxy-5-methoxyphenyl)hepta-1,6-diene-3,5-dione
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C21H18F2O6
 1
1
IC50 = 15600 nM
   TI
   LI
   LO
   TS
CP0078289
(E)-3,5-Bis[beta-(4-Hydroxy-3-methoxyphenyl)-ethenyl]-1H-pyrazole
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C21H20N2O4
 1
1
IC50 = 16200 nM
   TI
   LI
   LO
   TS
CP0122257
4-[(E)-2-[3-(4-hydroxy-3-methoxyphenyl)-1H-pyrazol-5-yl]ethenyl]-2-methoxyphenol
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C19H18N2O4
 1
1
IC50 = 18200 nM
   TI
   LI
   LO
   TS
CP0085054
(1E,4E)-1,5-bis(3-fluoro-4-hydroxy-5-methoxyphenyl)penta-1,4-dien-3-one
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C19H16F2O5
 1
1
IC50 = 19400 nM
   TI
   LI
   LO
   TS
CP0229013
(1E,4E)-1,5-bis[4-hydroxy-3-methoxy-5-(3-methylbut-2-enyl)phenyl]penta-1,4-dien-3-one
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C29H34O5
 1
1
IC50 = 22400 nM
   TI
   LI
   LO
   TS
CP0003494
US9187397, 1 (curcumin)
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C21H20O6
 1
1
IC50 = 33900 nM
   TI
   LI
   LO
   TS
CP0169287
(E)-1,5-bis(4-hydroxy-3-methoxyphenyl)pent-4-ene-1,3-dione
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C19H18O6
 1
1
IC50 = 35700 nM
   TI
   LI
   LO
   TS
CP0084929
1,7-Bis-(4-hydroxy-3-methoxy-phenyl)-heptane-3,5-dione
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C21H24O6
 1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0084930
(1E,6E)-1,7-bis[4-hydroxy-3-methoxy-5-(3-methylbut-2-enyl)phenyl]hepta-1,6-diene-3,5-dione
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C31H36O6
 1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0122259
4-[(E)-2-[3-[(E)-2-[4-hydroxy-3-methoxy-5-(3-methylbut-2-enyl)phenyl]ethenyl]-1H-pyrazol-5-yl]ethenyl]-2-methoxy-6-(3-methylbut-2-enyl)phenol
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C31H36N2O4
 1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0169284
1,7-bis[4-hydroxy-3-methoxy-5-(3-methylbutyl)phenyl]heptane-3,5-dione
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C31H44O6
 1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS