| Compound ID |
Compound Name |
Compound Formula |
|
CP0204318
|
(5S,8S,14S,17S,20S,23S,26S,29S,32S)-26-((1H-imidazol-5-yl)methyl)-32-amino-14,17,20-tribenzyl-5-carbamoyl-23-(carboxymethyl)-8-isobutyl-15-methyl-29-(2-(methylthio)ethyl)-7,10,13,16,19,22,25,28,31-nonaoxo-2-thia-6,9,12,15,18,21,24,27,30-nonaazatetratriacontan-34-oic acid
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|
C60H81N13O14S2
|
3
|
| 1 |
EC50 = 0.71 nM
|
|
|
| 2 |
EC50 = 2.22 nM
|
|
|
| 3 |
EC50 = 3.48 nM
|
|
|
|
CP0114970
|
(S)-(-)-N-(R-ethylbenzyl)-3-hydroxy-2-phenylquinoline-4-carboxamide
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|
C25H22N2O2
|
13
|
| 1 |
IC50 = 6.1 nM
|
|
|
| 2 |
IC50 = 16.6 nM
|
|
|
| 3 |
Kd = 2.344 nM
|
|
|
| 4 |
Kd = 2.884 nM
|
|
|
| 5 |
Kd = 5.754 nM
|
|
|
| 6 |
Kd = 229.09 nM
|
|
|
| 7 |
Ki = 1.7 nM
|
|
|
| 8 |
Ki = 3 nM
|
|
|
| 9 |
Ki = 3.6 nM
|
|
|
| 10 |
Ki = 3.7 nM
|
|
|
| 11 |
Ki = 10.6 nM
|
|
|
| 12 |
Ki = 37.2 nM
|
|
|
| 13 |
Ki = 122 nM
|
|
|
|
CP0514852
|
2-phenyl-N-(1-(pyridin-2-yl)propyl)quinoline-4-carboxamide
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|
C24H21N3O
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0431082
|
2-Phenyl-quinoline-4-carboxylic acid (1-phenyl-ethyl)-amide
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|
C24H20N2O
|
1
|
| 1 |
IC50 = 9900 nM
|
|
|
|
CP0849053
|
[3H]-(S)-(+)-N-((3-[1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl)-4-phenylpiperidin-4-yl)-N-methylacetamine
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|
C35H41Cl2N3O2
|
5
|
| 1 |
Kd = 0.08 nM
|
|
|
| 2 |
Kd = 0.2 nM
|
|
|
| 3 |
Kd = 0.7 nM
|
|
|
| 4 |
Kd = 1 nM
|
|
|
| 5 |
Kd = 2.2 nM
|
|
|
|
CP0074738
|
(S)-(+)-N-((3-[1-Benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl)-4-phenylpiperidin-4-yl)-N-methylacetamine
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|
C35H41Cl2N3O2
|
12
|
| 1 |
Kd = 0.2 nM
|
|
|
| 2 |
Kd = 0.22 nM
|
|
|
| 3 |
Kd = 5.888 nM
|
|
|
| 4 |
Kd = 16.98 nM
|
|
|
| 5 |
Kd = 18.62 nM
|
|
|
| 6 |
Kd = 29.51 nM
|
|
|
| 7 |
Ki = 0.4 nM
|
|
|
| 8 |
Ki = 0.5 nM
|
|
|
| 9 |
Ki = 0.6 nM
|
|
|
| 10 |
Ki = 2.1 nM
|
|
|
| 11 |
Ki = 4.8 nM
|
|
|
| 12 |
Ki = 10.8 nM
|
|
|
|
CP0461842
|
3-[1,4']Bipiperidinyl-1'-ylmethyl-2-phenyl-quinoline-4-carboxylic acid (1-cyclohexyl-ethyl)-amide
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|
C35H46N4O
|
1
|
| 1 |
Kd = 1.995 nM
|
|
|
|
CP0376847
|
2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methylphenyl)-6-(4-methylsulfonylpiperazin-1-yl)pyridin-3-yl]-N,2-dimethylpropanamide
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|
C30H31F7N4O3S
|
4
|
| 1 |
Kd = 2.455 nM
|
|
|
| 2 |
Kd = 123.03 nM
|
|
|
| 3 |
Ki = 0.7 nM
|
|
|
| 4 |
Ki = 2.4 nM
|
|
|
|
CP0374063
|
4-[4-(acetylmethyl-amino)-piperidin-1-yl]-2-(3,4-dichlorophenyl)-N-(4-fluoro-3-trifluoromethylbenzyl)-2,N-dimethylbutyramide
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|
C28H33Cl2F4N3O2
|
2
|
| 1 |
Kd = 7.762 nM
|
|
|
| 2 |
Ki = 3.1 nM
|
|
|
|
CP0376631
|
2-(3,4-dichlorophenyl)-N-(4-fluoro-3-trifluoromethylbenzyl)-2,N-dimethyl-4-[4-(2-oxo-pyrrolidin-1-yl)-piperidin-1-yl]-butyramide
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|
C29H33Cl2F4N3O2
|
2
|
| 1 |
Kd = 8.913 nM
|
|
|
| 2 |
Ki = 0.8 nM
|
|
|
|
CP0410452
|
2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methylphenyl)-6-[(3S)-3-methyl-4-methylsulfonylpiperazin-1-yl]pyridin-3-yl]-N,2-dimethylpropanamide
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|
C31H33F7N4O3S
|
8
|
| 1 |
Kd = 16.22 nM
|
|
|
| 2 |
Kd = 47.86 nM
|
|
|
| 3 |
Ki = 0.2 nM
|
|
|
| 4 |
Ki = 1.7 nM
|
|
|
| 5 |
Ki = 1.8 nM
|
|
|
| 6 |
Ki = 5.1 nM
|
|
|
| 7 |
Ki = 19.7 nM
|
|
|
| 8 |
Ki > 10000 nM
|
|
|
|
CP0397341
|
4-[4-(acetylmethyl-amino)-piperidin-1-yl]-N-(2-chloro-benzyl)-2-(3,4-dichlorophenyl)-2,N-dimethylbutyramide
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|
C27H34Cl3N3O2
|
2
|
| 1 |
Kd = 18.2 nM
|
|
|
| 2 |
Ki = 10.4 nM
|
|
|
|
CP0381342
|
2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methylphenyl)-6-[(3S)-3-hydroxypyrrolidin-1-yl]pyridin-3-yl]-N,2-dimethylpropanamide
Show/Hide
|
C29H28F7N3O2
|
4
|
| 1 |
Kd = 20.89 nM
|
|
|
| 2 |
Kd = 120.23 nM
|
|
|
| 3 |
Ki = 2.5 nM
|
|
|
| 4 |
Ki = 11.9 nM
|
|
|
|
CP0462726
|
2-[3,5-bis(trifluoromethyl)phenyl]-N-[6-(4,4-dioxo-1-oxa-4lambda6-thia-8-azaspiro[4.5]decan-8-yl)-4-(4-fluoro-2-methylphenyl)pyridin-3-yl]-N,2-dimethylpropanamide
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|
C32H32F7N3O4S
|
4
|
| 1 |
Kd = 37.15 nM
|
|
|
| 2 |
Kd = 97.72 nM
|
|
|
| 3 |
Ki = 1 nM
|
|
|
| 4 |
Ki = 3.5 nM
|
|
|
|
CP0513378
|
US9346786, 43
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|
C31H30ClF2N5O3
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0499613
|
US9346786, 59
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|
C32H33ClF2N4O4
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0516435
|
US9346786, 116
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|
C32H33Cl2FN4O4
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0526200
|
US9346786, 113
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|
C30H30Cl3FN4O3
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0376848
|
2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methylphenyl)-6-[(2S)-2-(hydroxymethyl)-4-methylsulfonylpiperazin-1-yl]pyridin-3-yl]-N,2-dimethylpropanamide
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|
C31H33F7N4O4S
|
2
|
| 1 |
Ki = 0.6 nM
|
|
|
| 2 |
Ki = 1.2 nM
|
|
|
|
CP0381321
|
2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methylphenyl)-6-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]pyridin-3-yl]-N,2-dimethylpropanamide
Show/Hide
|
C30H30F7N3O2
|
2
|
| 1 |
Ki = 0.6 nM
|
|
|
| 2 |
Ki = 1.5 nM
|
|
|
|
CP0484439
|
US9346786, 41
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|
C30H30Cl2F2N4O3
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0282991
|
2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methylphenyl)-6-[(2R,3S)-3-hydroxy-2-(hydroxymethyl)pyrrolidin-1-yl]pyridin-3-yl]-N,2-dimethylpropanamide
Show/Hide
|
C30H30F7N3O3
|
6
|
| 1 |
Ki = 0.7 nM
|
|
|
| 2 |
Ki = 2.9 nM
|
|
|
| 3 |
Ki = 3.4 nM
|
|
|
| 4 |
Ki = 3.9 nM
|
|
|
| 5 |
Ki = 12.5 nM
|
|
|
| 6 |
Ki = 2010 nM
|
|
|
|
CP0400484
|
US9346786, 57
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|
C30H29ClF2N6O3
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0479658
|
US9346786, 40
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|
C31H30ClF2N5O3
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0494890
|
US9346786, 63
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|
C31H33ClF2N4O5S
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0561619
|
US9346786, 61
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|
C30H29ClF2N6O3
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0562905
|
US9346786, 112
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|
C30H30Cl2F2N4O3
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0540024
|
US9346786, 115
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|
C31H32Cl2FN5O4
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0491073
|
US9346786, 46
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|
C30H30ClF3N4O3
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0561620
|
US9346786, 66
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|
C30H32ClF4N3O4
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0565485
|
US9346786, 114
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|
C31H30Cl2F4N4O3
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0494895
|
US9346786, 120
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|
C32H33ClF2N4O4
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0513349
|
US9346786, 109
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|
C32H33ClF2N4O4
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0494894
|
US9346786, 118
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|
C30H30Cl2F2N4O3
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0484437
|
US9346786, 17
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|
C30H30ClFN6O3
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0484443
|
US9346786, 80
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|
C27H30ClF2N3O4
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0494885
|
US9346786, 16
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|
C31H34ClFN4O5S
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0494891
|
US9346786, 68
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|
C31H33ClF5N3O4
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0494892
|
US9346786, 72
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|
C30H31ClF2N4O4
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0513358
|
US9346786, 47
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|
C31H33ClF2N4O3
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0513382
|
US9346786, 67
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|
C30H34ClF2N3O4
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0540018
|
US9346786, 48
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|
C31H30F3N5O3
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0561612
|
US9346786, 18
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|
C30H30ClFN6O3
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0561613
|
US9346786, 21
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|
C31H31ClFN5O3
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0561618
|
US9346786, 51
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|
C31H30F3N5O3
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0561621
|
US9346786, 69
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|
C30H33ClF3N3O4
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0566370
|
US9346786, 42
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|
C31H30ClF5N4O3
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0566371
|
US9346786, 44
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|
C30H34ClF2N3O4
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0544756
|
US8618303, 9
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|
C31H31ClFN5O3
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0540022
|
US9346786, 87
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|
C30H35ClFN3O4
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0565483
|
US9346786, 90
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|
C30H33ClF3N3O4
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0521617
|
US8618303, 18
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|
C31H31ClFN5O3
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0479659
|
US9346786, 45
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|
C31H30ClF2N5O3
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0484436
|
US9346786, 14
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|
C32H34ClFN4O4
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0490989
|
US9346786, 75
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|
C31H30ClF3N4O4
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0513360
|
US9346786, 73
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|
C33H40ClF2N3O5
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0540017
|
US9346786, 20
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|
C31H31ClF4N4O3
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0540020
|
US9346786, 65
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|
C30H34ClF2N3O5
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0483331
|
US9346786, 89
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|
C30H34ClF2N3O4
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0483347
|
US9346786, 117
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|
C30H30ClF3N4O3
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0492907
|
US9346786, 96
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|
C29H31ClF3N3O4
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0563779
|
US9346786, 100
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|
C31H37ClFN3O4
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0540025
|
US9346786, 119
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|
C31H30ClF5N4O3
|
1
|
| 1 |
Ki = 3.7 nM
|
|
|
|
CP0550970
|
US8618303, 10
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|
C32H32ClFN4O3
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0540021
|
US9346786, 83
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|
C33H37ClF2N4O4
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0479660
|
US9346786, 70
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|
C29H30ClF4N3O4
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0513359
|
US9346786, 60
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|
C32H33F3N4O4
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0554632
|
US9346786, 39
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|
C30H36ClF2N3O5
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0565480
|
US9346786, 35
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|
C31H31F2N5O3
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0565481
|
US9346786, 71
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|
C30H31ClF5N3O4
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0565482
|
US9346786, 77
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|
C32H31ClF3N3O4
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0526135
|
US9346786, 97
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|
C31H37ClFN3O5
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0476975
|
US8618303, 11
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|
C32H34ClFN4O4
|
1
|
| 1 |
Ki = 4.5 nM
|
|
|
|
CP0493194
|
US9346786, 108
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|
C32H36ClFN4O4
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0526136
|
US9346786, 99
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|
C31H37ClFN3O5
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0566378
|
US9346786, 98
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|
C33H41ClFN3O5
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0483336
|
US9346786, 110
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|
C30H31Cl2FN4O3
|
1
|
| 1 |
Ki = 4.8 nM
|
|
|
|
CP0560820
|
US8618303, 7
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|
C30H35ClFN3O4
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0466605
|
US9346786, 78
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|
C31H29ClF5N5O4
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0499614
|
US9346786, 64
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|
C31H33F3N4O5S
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0515274
|
US9346786, 58
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|
C30H29F3N6O3
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0540019
|
US9346786, 49
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|
C30H30ClF3N4O3
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0494893
|
US9346786, 88
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|
C30H35ClFN3O5
|
1
|
| 1 |
Ki = 5.6 nM
|
|
|
|
CP0400485
|
US9346786, 62
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|
C30H29F3N6O3
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0489677
|
US9346786, 123
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|
C32H34ClFN4O5
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0566377
|
US9346786, 95
Show/Hide
|
C30H32ClF4N3O4
|
1
|
| 1 |
Ki = 6.1 nM
|
|
|
|
CP0484444
|
US9346786, 91
Show/Hide
|
C31H37ClFN3O5
|
1
|
| 1 |
Ki = 6.5 nM
|
|
|
|
CP0484445
|
US9346786, 92
Show/Hide
|
C31H34ClF4N3O4
|
1
|
| 1 |
Ki = 6.6 nM
|
|
|
|
CP0477862
|
US9346786, 38
Show/Hide
|
C32H34F2N4O4
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0513381
|
US9346786, 54
Show/Hide
|
C30H30F4N4O3
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0526134
|
US9346786, 93
Show/Hide
|
C28H30ClFN4O4
|
1
|
| 1 |
Ki = 7.1 nM
|
|
|
|
CP0497609
|
US9346786, 111
Show/Hide
|
C31H33ClFN5O4
|
1
|
| 1 |
Ki = 7.4 nM
|
|
|
|
CP0521028
|
US8618303, 12
Show/Hide
|
C30H31ClF2N4O3
|
1
|
| 1 |
Ki = 7.6 nM
|
|
|
|
CP0479662
|
US9346786, 94
Show/Hide
|
C30H32ClFN4O4
|
1
|
| 1 |
Ki = 7.8 nM
|
|
|
|
CP0490991
|
US9346786, 79
Show/Hide
|
C32H30ClF2N5O4
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0494889
|
US9346786, 37
Show/Hide
|
C31H34F2N4O5S
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0561611
|
US9346786, 15
Show/Hide
|
C31H31ClFN5O3
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0565479
|
US9346786, 13
Show/Hide
|
C30H30ClFN6O3
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0412554
|
US8618303, 31
Show/Hide
|
C32H34ClFN4O4
|
1
|
| 1 |
Ki = 8.1 nM
|
|
|
|
CP0486304
|
US9346786, 82
Show/Hide
|
C27H31ClFN3O4
|
1
|
| 1 |
Ki = 8.2 nM
|
|
|
|
CP0526137
|
US9346786, 102
Show/Hide
|
C31H31ClF2N4O4
|
1
|
| 1 |
Ki = 8.2 nM
|
|
|
|
CP0499611
|
US9346786, 50
Show/Hide
|
C31H30F6N4O3
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0519234
|
US9346786, 55
Show/Hide
|
C31H33F3N4O3
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0412458
|
US8618303, 32
Show/Hide
|
C30H31Cl2FN4O3
|
1
|
| 1 |
Ki = 9.9 nM
|
|
|
|
CP0550619
|
US8618303, 13
Show/Hide
|
C30H31Cl2FN4O3
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0561617
|
US9346786, 36
Show/Hide
|
C30H31ClF2N4O3
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0565478
|
US9346786, 4
Show/Hide
|
C31H34Cl2FN3O4
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0460122
|
US8618303, 1
Show/Hide
|
C29H35ClFN3O4
|
1
|
| 1 |
Ki = 10.5 nM
|
|
|
|
CP0472584
|
US8618303, 22
Show/Hide
|
C32H32ClFN4O3
|
1
|
| 1 |
Ki = 10.5 nM
|
|
|
|
CP0550177
|
US8618303, 15
Show/Hide
|
C31H31ClF4N4O3
|
1
|
| 1 |
Ki = 11.5 nM
|
|
|
|
CP0437572
|
US8618303, 4
Show/Hide
|
C27H31ClFN3O4
|
1
|
| 1 |
Ki = 11.6 nM
|
|
|
|
CP0492905
|
US9346786, 74
Show/Hide
|
C32H30ClF5N4O4
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0515273
|
US9346786, 29
Show/Hide
|
C32H31ClFN5O3
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0550973
|
US8618303, 19
Show/Hide
|
C30H33ClFN5O4
|
1
|
| 1 |
Ki = 12.9 nM
|
|
|
|
CP0521027
|
US8618303, 8
Show/Hide
|
C31H34ClFN4O3
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0499612
|
US9346786, 52
Show/Hide
|
C30H34F3N3O4
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0513380
|
US9346786, 53
Show/Hide
|
C31H30F3N5O3
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0562906
|
US9346786, 121
Show/Hide
|
C29H32ClFN4O5
|
1
|
| 1 |
Ki = 16.9 nM
|
|
|
|
CP0490990
|
US9346786, 76
Show/Hide
|
C33H31ClF2N4O4
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0479663
|
US9346786, 104
Show/Hide
|
C34H42ClFN4O5
|
1
|
| 1 |
Ki = 17.6 nM
|
|
|
|
CP0564556
|
US8618303, 33
Show/Hide
|
C31H31ClF4N4O3
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0524509
|
US8618303, 2
Show/Hide
|
C31H39ClFN3O3
|
1
|
| 1 |
Ki = 20.1 nM
|
|
|
|
CP0494887
|
US9346786, 23
Show/Hide
|
C32H33ClFN5O3
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0476977
|
US8618303, 35
Show/Hide
|
C30H33ClFN5O4
|
1
|
| 1 |
Ki = 21.3 nM
|
|
|
|
CP0516433
|
US9346786, 12
Show/Hide
|
C30H30ClFN6O3
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0493192
|
US9346786, 85
Show/Hide
|
C30H32ClFN4O4
|
1
|
| 1 |
Ki = 23.3 nM
|
|
|
|
CP0549293
|
US8618303, 29
Show/Hide
|
C31H34ClFN4O3
|
1
|
| 1 |
Ki = 24.5 nM
|
|
|
|
CP0561614
|
US9346786, 22
Show/Hide
|
C31H31ClFN5O3
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0486302
|
US9346786, 81
Show/Hide
|
C26H30ClF2N3O5S
|
1
|
| 1 |
Ki = 29 nM
|
|
|
|
CP0493424
|
US9346786, 84
Show/Hide
|
C30H35ClFN3O5
|
1
|
| 1 |
Ki = 29.8 nM
|
|
|
|
CP0563780
|
US9346786, 105
Show/Hide
|
C28H32ClF2N3O4
|
1
|
| 1 |
Ki = 31.2 nM
|
|
|
|
CP0550974
|
US8618303, 21
Show/Hide
|
C30H35ClFN3O4
|
1
|
| 1 |
Ki = 31.9 nM
|
|
|
|
CP0484446
|
US9346786, 103
Show/Hide
|
C31H36ClFN4O5
|
1
|
| 1 |
Ki = 32.6 nM
|
|
|
|
CP0561615
|
US9346786, 30
Show/Hide
|
C33H34ClFN4O4
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0550972
|
US8618303, 17
Show/Hide
|
C29H26ClFN4O4
|
1
|
| 1 |
Ki = 35.4 nM
|
|
|
|
CP0489627
|
US9346786, 11
Show/Hide
|
C30H30ClFN6O3
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0564554
|
US8618303, 24
Show/Hide
|
C29H35ClFN3O4
|
1
|
| 1 |
Ki = 39.2 nM
|
|
|
|
CP0512359
|
US9346786, 101
Show/Hide
|
C32H31ClF4N4O4
|
1
|
| 1 |
Ki = 42.5 nM
|
|
|
|
CP0476976
|
US8618303, 23
Show/Hide
|
C30H31ClF2N4O3
|
1
|
| 1 |
Ki = 43.5 nM
|
|
|
|
CP0494888
|
US9346786, 26
Show/Hide
|
C31H32ClFN6O3
|
1
|
| 1 |
Ki = 46 nM
|
|
|
|
CP0513376
|
US9346786, 2
Show/Hide
|
C31H36Cl2FN3O4
|
1
|
| 1 |
Ki = 46 nM
|
|
|
|
CP0484438
|
US9346786, 27
Show/Hide
|
C31H32ClFN6O3
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0483329
|
US9346786, 33
Show/Hide
|
C31H30ClFN6O3
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0499610
|
US9346786, 28
Show/Hide
|
C32H33ClFN5O3
|
1
|
| 1 |
Ki = 50 nM
|
|
|
|
CP0437575
|
US8618303, 27
Show/Hide
|
C27H31ClFN3O4
|
1
|
| 1 |
Ki = 51 nM
|
|
|
|
CP0561616
|
US9346786, 32
Show/Hide
|
C31H30ClFN6O3
|
1
|
| 1 |
Ki = 52 nM
|
|
|
|
CP0540035
|
US9346786, 8
Show/Hide
|
C32H34ClFN4O4
|
1
|
| 1 |
Ki = 55 nM
|
|
|
|
CP0489628
|
US9346786, 31
Show/Hide
|
C32H31ClF4N4O3
|
1
|
| 1 |
Ki = 57 nM
|
|
|
|
CP0516432
|
US9346786, 6
Show/Hide
|
C30H34Cl2FN3O4
|
1
|
| 1 |
Ki = 62 nM
|
|
|
|
CP0554631
|
US9346786, 24
Show/Hide
|
C33H36ClFN4O4
|
1
|
| 1 |
Ki = 62 nM
|
|
|
|
CP0550969
|
US8618303, 6
Show/Hide
|
C25H24ClFN4O3
|
1
|
| 1 |
Ki = 64.9 nM
|
|
|
|
CP0540016
|
US9346786, 10
Show/Hide
|
C31H34ClFN4O5S
|
1
|
| 1 |
Ki = 65 nM
|
|
|
|
CP0500948
|
US9346786, 106
Show/Hide
|
C29H31F3N4O5
|
1
|
| 1 |
Ki = 66 nM
|
|
|
|
CP0550176
|
US8618303, 3
Show/Hide
|
C27H23ClFN3O3
|
1
|
| 1 |
Ki = 67.8 nM
|
|
|
|
CP0484447
|
US9346786, 122
Show/Hide
|
C36H43F2N5O4
|
1
|
| 1 |
Ki = 69.6 nM
|
|
|
|
CP0566376
|
US9346786, 86
Show/Hide
|
C32H31ClF4N4O4
|
1
|
| 1 |
Ki = 70.7 nM
|
|
|
|
CP0550971
|
US8618303, 14
Show/Hide
|
C26H22ClFN4O3
|
1
|
| 1 |
Ki = 77.4 nM
|
|
|
|
CP0437573
|
US8618303, 5
Show/Hide
|
C25H28ClFN2O4
|
1
|
| 1 |
Ki = 86.4 nM
|
|
|
|
CP0494886
|
US9346786, 19
Show/Hide
|
C31H31ClF4N4O3
|
1
|
| 1 |
Ki = 88 nM
|
|
|
|
CP0540034
|
US9346786, 7
Show/Hide
|
C30H30ClFN6O3
|
1
|
| 1 |
Ki = 89 nM
|
|
|
|
CP0437574
|
US8618303, 25
Show/Hide
|
C31H39ClFN3O3
|
1
|
| 1 |
Ki = 91.5 nM
|
|
|
|
CP0499609
|
US9346786, 25
Show/Hide
|
C32H33ClF4N4O3
|
1
|
| 1 |
Ki = 112 nM
|
|
|
|
CP0479657
|
US9346786, 34
Show/Hide
|
C32H31ClFN5O3
|
1
|
| 1 |
Ki = 116 nM
|
|
|
|
CP0540023
|
US9346786, 107
Show/Hide
|
C31H35F3N4O5
|
1
|
| 1 |
Ki = 131.2 nM
|
|
|
|
CP0540036
|
US9346786, 9
Show/Hide
|
C31H31ClFN5O3
|
1
|
| 1 |
Ki = 138 nM
|
|
|
|
CP0400483
|
US9346786, 56
Show/Hide
|
C25H28ClF2N3O3
|
1
|
| 1 |
Ki = 267 nM
|
|
|
|
CP0554127
|
US8618303, 20
Show/Hide
|
C31H31ClFN3O4
|
1
|
| 1 |
Ki = 275.7 nM
|
|
|
|
CP0512319
|
US9346786, 3
Show/Hide
|
C32H38Cl2FN3O4
|
1
|
| 1 |
Ki = 276 nM
|
|
|
|
CP0560821
|
US8618303, 16
Show/Hide
|
C32H27ClF2N2O3
|
1
|
| 1 |
Ki = 299.7 nM
|
|
|
|
CP0468048
|
US8618303, 28
Show/Hide
|
C25H28ClFN2O4
|
1
|
| 1 |
Ki = 347.6 nM
|
|
|
|
CP0107813
|
3-[2-{1-[3,5-di(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)-1,4-oxazinan-4-ylmethyl]-4,5-dihydro-1H-1,2,4-triazol-5-one
Show/Hide
|
C23H21F7N4O3
|
1
|
| 1 |
Ki = 454.1 nM
|
|
|
|
CP0549292
|
US8618303, 26
Show/Hide
|
C27H23ClFN3O3
|
1
|
| 1 |
Ki = 629.4 nM
|
|
|
|
CP0521029
|
US8618303, 36
Show/Hide
|
C31H31ClFN3O4
|
1
|
| 1 |
Ki = 997.3 nM
|
|
|
|
CP0133180
|
((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-(2-methoxy-benzyl)-amine
Show/Hide
|
C28H32N2O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
