Brief Information of the Compound and Protein
Compound Name
[3H]-(S)-(+)-N-((3-[1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl)-4-phenylpiperidin-4-yl)-N-methylacetamine
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PubChem ID
CID: 71717901
Canonical SMILES
[3H]c1cccc(C2(N(C)C(C)=O)CCN(CCC[C@]3(c4ccc(Cl)c(Cl)c4)CCCN(C(=O)c4ccccc4)C3)CC2)c1
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Compound Formula C35H41Cl2N3O2
Compound Structure
Protein Name
Neuromedin-K receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P29371
Gene Name
TACR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  5
1
Kd = 0.08 nM
   TI
   LI
   LO
   TS
2
Kd = 0.2 nM
   TI
   LI
   LO
   TS
3
Kd = 0.7 nM
   TI
   LI
   LO
   TS
4
Kd = 1 nM
   TI
   LI
   LO
   TS
5
Kd = 2.2 nM
   TI
   LI
   LO
   TS