| Compound ID |
Compound Name |
Compound Formula |
|
CP0028363
|
1-[4-[4-[7-amino-2-(1,3-benzothiazol-7-yl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C24H22N6O2S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0032463
|
1-[4-[4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C23H21N7O2S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0029006
|
4-[4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]cyclohexan-1-ol
Show/Hide
|
C22H20N6O2S
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0025123
|
7-amino-2-(1,2,3-benzothiadiazol-7-yl)-4-[1-(4-hydroxycyclohexyl)pyrazol-4-yl]furo[2,3-c]pyridine-3-carbonitrile
Show/Hide
|
C23H19N7O2S
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0018592
|
4-[4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)-3-chlorofuro[2,3-c]pyridin-4-yl]pyrazol-1-yl]cyclohexan-1-ol
Show/Hide
|
C22H19ClN6O2S
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0018196
|
4-[4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)-3-(difluoromethyl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]cyclohexan-1-ol
Show/Hide
|
C23H20F2N6O2S
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0018308
|
4-[4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)-3-(1,3-thiazol-5-yl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]cyclohexan-1-ol
Show/Hide
|
C25H21N7O2S2
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0025066
|
1-[4-[4-[7-amino-2-(1,2-benzothiazol-7-yl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C24H22N6O2S
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0017901
|
4-[4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)-3-(fluoromethyl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]cyclohexan-1-ol
Show/Hide
|
C23H21FN6O2S
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0027279
|
1-[4-[4-(7-amino-2-thieno[2,3-c]pyridin-3-ylfuro[2,3-c]pyridin-4-yl)pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C24H22N6O2S
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0018195
|
4-[4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)-3-pyridin-3-ylfuro[2,3-c]pyridin-4-yl]pyrazol-1-yl]cyclohexan-1-ol
Show/Hide
|
C27H23N7O2S
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0029005
|
4-(1-methylpyrazol-4-yl)-2-thieno[2,3-c]pyridin-3-ylfuro[2,3-c]pyridin-7-amine
Show/Hide
|
C18H13N5OS
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0028856
|
1-[4-[4-[7-amino-2-(3-nitrophenyl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C23H22N6O4
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0015764
|
1-[4-[4-[7-amino-2-(1-methylpyrrolo[2,3-c]pyridin-3-yl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C25H25N7O2
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0031932
|
3-[4-[1-(1-acetylpiperidin-4-yl)pyrazol-4-yl]-7-aminofuro[2,3-c]pyridin-2-yl]benzonitrile
Show/Hide
|
C24H22N6O2
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0027278
|
1-[4-[4-[7-amino-2-(1-benzothiophen-3-yl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C25H23N5O2S
|
1
|
| 1 |
IC50 = 440 nM
|
|
|
|
CP0031931
|
1-[4-[4-[7-amino-2-[3-(hydroxymethyl)phenyl]furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C24H25N5O3
|
1
|
| 1 |
IC50 = 470 nM
|
|
|
|
CP0017335
|
1-[4-[4-[7-amino-2-(2-methylsulfanylphenyl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C24H25N5O2S
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0028362
|
1-[4-[4-[7-amino-2-(4-hydroxyphenyl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C23H23N5O3
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0028855
|
1-[4-[4-[7-amino-2-(3-aminophenyl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C23H24N6O2
|
1
|
| 1 |
IC50 = 510 nM
|
|
|
|
CP0020429
|
1-[4-[4-(7-amino-2-phenylfuro[2,3-c]pyridin-4-yl)pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C23H23N5O2
|
1
|
| 1 |
IC50 = 520 nM
|
|
|
|
CP0031933
|
2-[2-[4-[1-(1-acetylpiperidin-4-yl)pyrazol-4-yl]-7-aminofuro[2,3-c]pyridin-2-yl]phenyl]acetonitrile
Show/Hide
|
C25H24N6O2
|
1
|
| 1 |
IC50 = 530 nM
|
|
|
|
CP0025065
|
1-[4-[4-[7-amino-2-(3-hydroxyphenyl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C23H23N5O3
|
1
|
| 1 |
IC50 = 610 nM
|
|
|
|
CP0015760
|
1-[4-[4-[7-amino-2-[3-(dimethylamino)phenyl]furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C25H28N6O2
|
1
|
| 1 |
IC50 = 690 nM
|
|
|
|
CP0017328
|
1-[3-[4-[1-(1-acetylpiperidin-4-yl)pyrazol-4-yl]-7-aminofuro[2,3-c]pyridin-2-yl]phenyl]ethanone
Show/Hide
|
C25H25N5O3
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0025063
|
1-[4-[4-[7-amino-2-(4-aminophenyl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C23H24N6O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0031773
|
4-(1,3-dimethylpyrazol-4-yl)-2-thieno[2,3-c]pyridin-3-ylfuro[2,3-c]pyridin-7-amine
Show/Hide
|
C19H15N5OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0023871
|
1-[4-[4-[7-amino-2-(3-methylsulfonylphenyl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C24H25N5O4S
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0023875
|
3-[4-[1-(1-acetylpiperidin-4-yl)pyrazol-4-yl]-7-aminofuro[2,3-c]pyridin-2-yl]-N,N-dimethylbenzenesulfonamide
Show/Hide
|
C25H28N6O4S
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0015759
|
1-[4-[4-[7-amino-2-(3-methylsulfanylphenyl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C24H25N5O2S
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0017329
|
1-[4-[4-[7-amino-2-(3-methoxyphenyl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C24H25N5O3
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0028944
|
1-[4-[4-(7-amino-2-naphthalen-1-ylfuro[2,3-c]pyridin-4-yl)pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C27H25N5O2
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0017333
|
1-[4-[4-[7-amino-2-[2-(hydroxymethyl)phenyl]furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C24H25N5O3
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0023874
|
1-[4-[4-[7-amino-2-[3-(trifluoromethyl)phenyl]furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C24H22F3N5O2
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0020431
|
2-[4-[1-(1-acetylpiperidin-4-yl)pyrazol-4-yl]-7-aminofuro[2,3-c]pyridin-2-yl]benzonitrile
Show/Hide
|
C24H22N6O2
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0031774
|
4-(3-methoxy-1-methylpyrazol-4-yl)-2-thieno[2,3-c]pyridin-3-ylfuro[2,3-c]pyridin-7-amine
Show/Hide
|
C19H15N5O2S
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0027277
|
1-[4-[4-[7-amino-2-[2-(methoxymethyl)phenyl]furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C25H27N5O3
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0032461
|
1-[4-[4-[7-amino-2-[3-(trifluoromethoxy)phenyl]furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C24H22F3N5O3
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0015761
|
2-[4-[4-[1-(1-acetylpiperidin-4-yl)pyrazol-4-yl]-7-aminofuro[2,3-c]pyridin-2-yl]phenyl]acetonitrile
Show/Hide
|
C25H24N6O2
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0023387
|
1-[4-[4-[7-amino-2-[3-(2-methoxyethoxy)phenyl]furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C26H29N5O4
|
1
|
| 1 |
IC50 = 2700 nM
|
|
|
|
CP0025062
|
4-[4-[1-(1-acetylpiperidin-4-yl)pyrazol-4-yl]-7-aminofuro[2,3-c]pyridin-2-yl]benzonitrile
Show/Hide
|
C24H22N6O2
|
1
|
| 1 |
IC50 = 2800 nM
|
|
|
|
CP0031772
|
4-(1,5-dimethylpyrazol-4-yl)-2-thieno[2,3-c]pyridin-3-ylfuro[2,3-c]pyridin-7-amine
Show/Hide
|
C19H15N5OS
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0015757
|
1-[2-[4-[1-(1-acetylpiperidin-4-yl)pyrazol-4-yl]-7-aminofuro[2,3-c]pyridin-2-yl]phenyl]ethanone
Show/Hide
|
C25H25N5O3
|
1
|
| 1 |
IC50 = 3100 nM
|
|
|
|
CP0025064
|
3-[4-[1-(1-acetylpiperidin-4-yl)pyrazol-4-yl]-7-aminofuro[2,3-c]pyridin-2-yl]benzamide
Show/Hide
|
C24H24N6O3
|
1
|
| 1 |
IC50 = 3100 nM
|
|
|
|
CP0032462
|
1-[4-[4-[7-amino-2-[3-(aminomethyl)phenyl]furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C24H26N6O2
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0031927
|
1-[4-[4-[7-amino-2-[4-(hydroxymethyl)phenyl]furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C24H25N5O3
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
|
CP0018193
|
2-thieno[2,3-c]pyridin-3-yl-4-(1,3,5-trimethylpyrazol-4-yl)furo[2,3-c]pyridin-7-amine
Show/Hide
|
C20H17N5OS
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
|
CP0023870
|
2-[4-[1-(1-acetylpiperidin-4-yl)pyrazol-4-yl]-7-aminofuro[2,3-c]pyridin-2-yl]benzamide
Show/Hide
|
C24H24N6O3
|
1
|
| 1 |
IC50 = 4500 nM
|
|
|
|
CP0015756
|
1-[4-[4-[7-amino-2-(4-methylsulfanylphenyl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C24H25N5O2S
|
1
|
| 1 |
IC50 = 5200 nM
|
|
|
|
CP0023872
|
1-[4-[4-[7-amino-2-[4-(trifluoromethoxy)phenyl]furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C24H22F3N5O3
|
1
|
| 1 |
IC50 = 8000 nM
|
|
|
|
CP0023873
|
N-[3-[4-[1-(1-acetylpiperidin-4-yl)pyrazol-4-yl]-7-aminofuro[2,3-c]pyridin-2-yl]phenyl]acetamide
Show/Hide
|
C25H26N6O3
|
1
|
| 1 |
IC50 = 9000 nM
|
|
|
|
CP0031934
|
1-[4-[4-[7-amino-2-(1H-pyrazol-4-yl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C20H21N7O2
|
1
|
| 1 |
IC50 = 9100 nM
|
|
|
|
CP0018194
|
4-(7-amino-2-thieno[2,3-c]pyridin-3-ylfuro[2,3-c]pyridin-4-yl)-1-methylpyrazole-3-carbonitrile
Show/Hide
|
C19H12N6OS
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0017326
|
1-[4-[4-[7-amino-2-(4-methylsulfonylphenyl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C24H25N5O4S
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
