Brief Information of the Compound and Protein
Compound Name
4-[4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)-3-pyridin-3-ylfuro[2,3-c]pyridin-4-yl]pyrazol-1-yl]cyclohexan-1-ol
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Canonical SMILES
Nc1ncc(-c2cnn(c2)[C@H]2CC[C@H](O)CC2)c2c(c(oc12)-c1cccc2nnsc12)-c1cccnc1
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Compound Formula C27H23N7O2S
Compound Structure
Protein Name
Mitogen-activated protein kinase kinase kinase 7
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase MLK family
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TKL protein kinase TAK1 subfamily
Uniprot ID
O43318
Gene Name
MAP3K7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116 Homo sapiens (Human)  1
1
IC50 = 130 nM
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