Brief Information of the Compound and Protein
Compound Name
4-[4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]cyclohexan-1-ol
    Show/Hide
Canonical SMILES
Nc1ncc(-c2cnn(c2)[C@H]2CC[C@H](O)CC2)c2cc(oc12)-c1cccc2nnsc12
    Show/Hide
Compound Formula C22H20N6O2S
Compound Structure
Protein Name
Mitogen-activated protein kinase kinase kinase 7
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase MLK family
>
TKL protein kinase TAK1 subfamily
Uniprot ID
O43318
Gene Name
MAP3K7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116 Homo sapiens (Human)  1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS