| Compound ID |
Compound Name |
Compound Formula |
|
CP0407179
|
US8754075, 1
Show/Hide
|
C17H15ClF2N4O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0470138
|
US8754075, 11
Show/Hide
|
C18H16F4N4O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0425312
|
US8754075, 39
Show/Hide
|
C18H16Cl2F2N4O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0389314
|
US8754075, 8
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|
C17H14ClF3N4O2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0544631
|
US8754075, 41
Show/Hide
|
C18H17ClF2N4O2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0407680
|
US8754075, 3
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|
C17H14F4N4O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0508727
|
US8754075, 20
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|
C17H15F3N4O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0544127
|
US8754075, 2
Show/Hide
|
C17H14Cl2F2N4O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0385717
|
US8754075, 14
Show/Hide
|
C22H20F2N4O2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0415557
|
US8754075, 7
Show/Hide
|
C18H14ClF2N5O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0478819
|
US9242943, 41
Show/Hide
|
C19H20F3N3O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0506748
|
US9242943, 24
Show/Hide
|
C20H19ClN4O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0403473
|
US8754075, 18
Show/Hide
|
C18H19F2N3O3
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0321772
|
N-[3-[(4R,5R)-2-amino-5-fluoro-4-methyl-5,6-dihydro-1,3-oxazin-4-yl]-4-fluorophenyl]-5-cyanopyridine-2-carboxamide
Show/Hide
|
C18H15F2N5O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0380937
|
US8754075, 38
Show/Hide
|
C19H17F2N5O2
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0414721
|
US8754075, 15
Show/Hide
|
C17H15F4N5O2
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0414023
|
US8754075, 40
Show/Hide
|
C17H16ClF4N5O2
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0472513
|
US8754075, 28
Show/Hide
|
C15H14ClF2N5O2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0440509
|
US8754075, 45
Show/Hide
|
C19H17ClF4N4O3
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0468441
|
US8754075, 13
Show/Hide
|
C18H18F2N4O3
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0536504
|
US8754075, 46
Show/Hide
|
C19H17F5N4O3
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0488985
|
US8754075, 48
Show/Hide
|
C19H16Cl2F4N4O3
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0374620
|
US8754075, 42
Show/Hide
|
C18H17F3N4O2
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
|
CP0563205
|
US9242943, 26
Show/Hide
|
C20H18ClFN4O
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0397102
|
US8754075, 5
Show/Hide
|
C18H17F3N4O3
|
1
|
| 1 |
IC50 = 106 nM
|
|
|
|
CP0396417
|
US8754075, 43
Show/Hide
|
C18H18ClF4N5O2
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0564906
|
US9242943, 37
Show/Hide
|
C21H22N4O2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0401342
|
US8754075, 22
Show/Hide
|
C20H20F2N4O2
|
1
|
| 1 |
IC50 = 124 nM
|
|
|
|
CP0544635
|
US8754075, 9
Show/Hide
|
C18H14ClF5N4O2
|
1
|
| 1 |
IC50 = 124 nM
|
|
|
|
CP0538190
|
US8754075, 44
Show/Hide
|
C16H17F4N3O2
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0529948
|
US9242943, 15
Show/Hide
|
C16H22FN3O
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0389338
|
US8754075, 37
Show/Hide
|
C20H19F5N4O3
|
1
|
| 1 |
IC50 = 226 nM
|
|
|
|
CP0402998
|
US8754075, 47
Show/Hide
|
C20H17F4N5O3
|
1
|
| 1 |
IC50 = 268 nM
|
|
|
|
CP0506747
|
US9242943, 21
Show/Hide
|
C15H20FN3O
|
1
|
| 1 |
IC50 = 279 nM
|
|
|
|
CP0527307
|
US9242943, 46
Show/Hide
|
C21H22N4O2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0512536
|
US8754075, 35
Show/Hide
|
C18H14ClF2N5O2
|
1
|
| 1 |
IC50 = 511 nM
|
|
|
|
CP0527305
|
US9242943, 27
Show/Hide
|
C20H17Cl2FN4O
|
1
|
| 1 |
IC50 = 558 nM
|
|
|
|
CP0544844
|
US8754075, 16
Show/Hide
|
C20H21F2N5O3
|
1
|
| 1 |
IC50 = 590 nM
|
|
|
|
CP0527303
|
US9242943, 6
Show/Hide
|
C16H24FN3O
|
1
|
| 1 |
IC50 = 605 nM
|
|
|
|
CP0389388
|
US8754075, 27
Show/Hide
|
C17H16F5N5O2
|
1
|
| 1 |
IC50 = 709 nM
|
|
|
|
CP0484138
|
US9242943, 35
Show/Hide
|
C20H21ClFN3O
|
1
|
| 1 |
IC50 = 732 nM
|
|
|
|
CP0564907
|
US9242943, 40
Show/Hide
|
C19H20ClFN4O
|
1
|
| 1 |
IC50 = 1097 nM
|
|
|
|
CP0572403
|
US9242943, 14
Show/Hide
|
C15H20FN3O
|
1
|
| 1 |
IC50 = 1170 nM
|
|
|
|
CP0141731
|
N-[3-[(4R,5S)-2-amino-5-fluoro-4-methyl-5,6-dihydro-1,3-oxazin-4-yl]-4-fluorophenyl]-5-cyanopyridine-2-carboxamide
Show/Hide
|
C18H15F2N5O2
|
1
|
| 1 |
IC50 = 1174 nM
|
|
|
|
CP0563206
|
US9242943, 33
Show/Hide
|
C14H15FN4O2
|
1
|
| 1 |
IC50 = 1210 nM
|
|
|
|
CP0385263
|
US8754075, 26
Show/Hide
|
C15H13ClF2N4O2S
|
1
|
| 1 |
IC50 = 1405 nM
|
|
|
|
CP0527306
|
US9242943, 34
Show/Hide
|
C19H19ClFN5O
|
1
|
| 1 |
IC50 = 1481 nM
|
|
|
|
CP0539150
|
US9242943, 23
Show/Hide
|
C20H24ClFN4O
|
1
|
| 1 |
IC50 = 1662 nM
|
|
|
|
CP0506746
|
US9242943, 20
Show/Hide
|
C16H22FN3O2
|
1
|
| 1 |
IC50 = 2270 nM
|
|
|
|
CP0419448
|
US9242943, 29
Show/Hide
|
C21H19F3N4O2
|
1
|
| 1 |
IC50 = 2296 nM
|
|
|
|
CP0538398
|
US8754075, 17
Show/Hide
|
C19H17F5N4O3
|
1
|
| 1 |
IC50 = 2300 nM
|
|
|
|
CP0561337
|
US9242943, 22
Show/Hide
|
C16H22FN3O2
|
1
|
| 1 |
IC50 = 2430 nM
|
|
|
|
CP0529947
|
US9242943, 12
Show/Hide
|
C14H17F4N3O
|
1
|
| 1 |
IC50 = 2900 nM
|
|
|
|
CP0527304
|
US9242943, 18
Show/Hide
|
C15H20FN3O2
|
1
|
| 1 |
IC50 = 3391 nM
|
|
|
|
CP0508954
|
US9242943, 19
Show/Hide
|
C16H22FN3O2
|
1
|
| 1 |
IC50 = 3419 nM
|
|
|
|
CP0422514
|
US8754075, 36
Show/Hide
|
C18H14ClF5N4O2
|
1
|
| 1 |
IC50 = 4029 nM
|
|
|
