Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US8754075, 13
    Show/Hide
 PubChem ID
CID: 66558690
SID: 152189119
Canonical SMILES
COc1ccc(nc1)C(=O)Nc1ccc(F)c(c1)[C@@]1(C)N=C(N)OC[C@@H]1F
    Show/Hide
Compound Formula C18H18F2N4O3
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 2
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
Q9Y5Z0
Gene Name
BACE2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000416 INS-1E
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
IC50 = 65 nM
   TI
   LI
   LO
   TS