| Compound ID |
Compound Name |
Compound Formula |
|
CP0050330
|
5-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-benzo[d]imidazol-2-ylamino)benzene-1,3-diol
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|
C17H15N7O2
|
2
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 97 nM
|
|
|
|
CP0204367
|
3-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-benzo[d]imidazol-2-ylamino)phenol
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|
C17H15N7O
|
2
|
| 1 |
IC50 = 9 nM
|
|
|
| 2 |
IC50 = 150 nM
|
|
|
|
CP0050331
|
1-(4-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-benzo[d]imidazol-2-ylamino)phenyl)-3-methylurea
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|
C19H19N9O
|
2
|
| 1 |
IC50 = 11 nM
|
|
|
| 2 |
IC50 = 340 nM
|
|
|
|
CP0142914
|
2-(4-(2-(3-hydroxyphenylamino)-1H-benzo[d]imidazol-1-yl)-6-methyl-1,3,5-triazin-2-ylamino)acetonitrile
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|
C19H16N8O
|
2
|
| 1 |
IC50 = 17 nM
|
|
|
| 2 |
IC50 = 380 nM
|
|
|
|
CP0238827
|
3-(1-(4-amino-1,3,5-triazin-2-yl)-1H-benzo[d]imidazol-2-ylamino)phenol
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|
C16H13N7O
|
2
|
| 1 |
IC50 = 34 nM
|
|
|
| 2 |
IC50 = 710 nM
|
|
|
|
CP0238828
|
3-(1-(6-amino-2-methylpyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)phenol
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|
C18H16N6O
|
2
|
| 1 |
IC50 = 43 nM
|
|
|
| 2 |
IC50 = 1200 nM
|
|
|
|
CP0204366
|
1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-5,6-difluoro-N-(1H-pyrazol-3-yl)-1H-benzo[d]imidazol-2-amine
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|
C14H11F2N9
|
2
|
| 1 |
IC50 = 45 nM
|
|
|
| 2 |
IC50 = 340 nM
|
|
|
|
CP0050328
|
1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-N-(1H-pyrazol-3-yl)-1H-benzimidazol-2-amine
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|
C14H13N9
|
2
|
| 1 |
IC50 = 55 nM
|
|
|
| 2 |
IC50 = 390 nM
|
|
|
|
CP0160473
|
2-(4-(2-(1H-pyrazol-3-ylamino)-1H-benzo[d]imidazol-1-yl)-6-methyl-1,3,5-triazin-2-ylamino)acetonitrile
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|
C16H14N10
|
2
|
| 1 |
IC50 = 73 nM
|
|
|
| 2 |
IC50 = 600 nM
|
|
|
|
CP0169966
|
3-(4-(2-(1H-pyrazol-3-ylamino)-1H-benzo[d]imidazol-1-yl)-6-methyl-1,3,5-triazin-2-ylamino)propanenitrile
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|
C17H16N10
|
2
|
| 1 |
IC50 = 82 nM
|
|
|
| 2 |
IC50 = 1300 nM
|
|
|
|
CP0050336
|
1-(4-methyl-6-(methylamino)-1,3,5-triazin-2-yl)-N-(1H-pyrazol-3-yl)-1H-benzo[d]imidazol-2-amine
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|
C15H15N9
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
IC50 = 600 nM
|
|
|
|
CP0142926
|
N-[3-[[1-(4-amino-6-methyl-1,3,5-triazin-2-yl)benzimidazol-2-yl]amino]phenyl]acetamide
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|
C19H18N8O
|
2
|
| 1 |
IC50 = 120 nM
|
|
|
| 2 |
IC50 = 1500 nM
|
|
|
|
CP0287661
|
1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-N-(1H-indazol-6-yl)benzimidazol-2-amine
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|
C18H15N9
|
2
|
| 1 |
IC50 = 120 nM
|
|
|
| 2 |
IC50 = 1500 nM
|
|
|
|
CP0075072
|
1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-N-(1H-indol-6-yl)-1H-benzo[d]imidazol-2-amine
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|
C19H16N8
|
2
|
| 1 |
IC50 = 140 nM
|
|
|
| 2 |
IC50 = 960 nM
|
|
|
|
CP0137531
|
1-(4-methyl-6-(prop-2-ynylamino)-1,3,5-triazin-2-yl)-N-(1H-pyrazol-3-yl)-1H-benzo[d]imidazol-2-amine
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|
C17H15N9
|
2
|
| 1 |
IC50 = 150 nM
|
|
|
| 2 |
IC50 = 1400 nM
|
|
|
|
CP0050332
|
1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-N-(1H-pyrazol-4-yl)-1H-benzo[d]imidazol-2-amine
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|
C14H13N9
|
2
|
| 1 |
IC50 = 180 nM
|
|
|
| 2 |
IC50 = 5300 nM
|
|
|
|
CP0075071
|
N-[4-[[1-(4-amino-6-methyl-1,3,5-triazin-2-yl)benzimidazol-2-yl]amino]phenyl]acetamide
Show/Hide
|
C19H18N8O
|
2
|
| 1 |
IC50 = 180 nM
|
|
|
| 2 |
IC50 = 340 nM
|
|
|
|
CP0314463
|
3-(1-(4-(methylamino)-1,3,5-triazin-2-yl)-1H-benzo[d]imidazol-2-ylamino)phenol
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|
C17H15N7O
|
2
|
| 1 |
IC50 = 180 nM
|
|
|
| 2 |
IC50 = 2900 nM
|
|
|
|
CP0050333
|
3-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-benzo[d]imidazol-2-ylamino)benzamide
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|
C18H16N8O
|
2
|
| 1 |
IC50 = 190 nM
|
|
|
| 2 |
IC50 = 3900 nM
|
|
|
|
CP0219214
|
1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-N-phenyl-1H-benzo[d]imidazol-2-amine
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|
C17H15N7
|
2
|
| 1 |
IC50 = 190 nM
|
|
|
| 2 |
IC50 > 25000 nM
|
|
|
|
CP0142925
|
1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-N-(1H-indazol-3-yl)benzimidazol-2-amine
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|
C18H15N9
|
2
|
| 1 |
IC50 = 250 nM
|
|
|
| 2 |
IC50 = 4200 nM
|
|
|
|
CP0204448
|
N-[1-(4-amino-6-methyl-1,3,5-triazin-2-yl)benzimidazol-2-yl]-1,2-oxazol-3-amine
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|
C14H12N8O
|
2
|
| 1 |
IC50 = 260 nM
|
|
|
| 2 |
IC50 = 3300 nM
|
|
|
|
CP0204360
|
3-(1-(4-amino-6-ethyl-1,3,5-triazin-2-yl)-1H-benzo[d]imidazol-2-ylamino)phenol
Show/Hide
|
C18H17N7O
|
2
|
| 1 |
IC50 = 410 nM
|
|
|
| 2 |
IC50 = 6300 nM
|
|
|
|
CP0345668
|
3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)phenol
Show/Hide
|
C17H14N6O
|
2
|
| 1 |
IC50 = 420 nM
|
|
|
| 2 |
IC50 = 3500 nM
|
|
|
|
CP0160282
|
1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-N-(1-methyl-1H-pyrazol-5-yl)-1H-benzo[d]imidazol-2-amine
Show/Hide
|
C15H15N9
|
2
|
| 1 |
IC50 = 540 nM
|
|
|
| 2 |
IC50 > 25000 nM
|
|
|
|
CP0204363
|
1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-N-(1-methyl-1H-pyrazol-3-yl)-1H-benzo[d]imidazol-2-amine
Show/Hide
|
C15H15N9
|
2
|
| 1 |
IC50 = 580 nM
|
|
|
| 2 |
IC50 = 5300 nM
|
|
|
|
CP0297677
|
3-(1-(2-methylpyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)phenol
Show/Hide
|
C18H15N5O
|
2
|
| 1 |
IC50 = 600 nM
|
|
|
| 2 |
IC50 = 8900 nM
|
|
|
|
CP0050334
|
1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)-1H-benzo[d]imidazol-2-amine
Show/Hide
|
C16H19N7O
|
2
|
| 1 |
IC50 = 680 nM
|
|
|
| 2 |
IC50 > 25000 nM
|
|
|
|
CP0137535
|
5-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-benzo[d]imidazol-2-ylamino)-N-methylfuran-2-carboxamide
Show/Hide
|
C17H16N8O2
|
2
|
| 1 |
IC50 = 680 nM
|
|
|
| 2 |
IC50 > 25000 nM
|
|
|
|
CP0050326
|
2-(4-(2-(3-hydroxyphenylamino)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazin-2-ylamino)acetonitrile
Show/Hide
|
C18H14N8O
|
2
|
| 1 |
IC50 = 700 nM
|
|
|
| 2 |
IC50 = 1700 nM
|
|
|
|
CP0050329
|
1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-N-(1-(difluoromethyl)-1H-pyrazol-3-yl)-1H-benzo[d]imidazol-2-amine
Show/Hide
|
C15H13F2N9
|
2
|
| 1 |
IC50 = 770 nM
|
|
|
| 2 |
IC50 = 6500 nM
|
|
|
|
CP0050327
|
3-(1-(4-(phenylamino)-1,3,5-triazin-2-yl)-1H-benzo[d]imidazol-2-ylamino)phenol
Show/Hide
|
C22H17N7O
|
2
|
| 1 |
IC50 = 870 nM
|
|
|
| 2 |
IC50 > 25000 nM
|
|
|
|
CP0219140
|
3-(1-(1,3,5-triazin-2-yl)-1H-benzo[d]imidazol-2-ylamino)phenol
Show/Hide
|
C16H12N6O
|
2
|
| 1 |
IC50 = 1600 nM
|
|
|
| 2 |
IC50 > 25000 nM
|
|
|
|
CP0169967
|
3-(1-(4-methoxy-1,3,5-triazin-2-yl)-1H-benzo[d]imidazol-2-ylamino)phenol
Show/Hide
|
C17H14N6O2
|
2
|
| 1 |
IC50 = 1900 nM
|
|
|
| 2 |
IC50 > 25000 nM
|
|
|
|
CP0137572
|
2-(4-(2-(3-hydroxyphenylamino)-1H-benzo[d]imidazol-1-yl)-6-methoxy-1,3,5-triazin-2-ylamino)acetonitrile
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|
C19H16N8O2
|
2
|
| 1 |
IC50 = 2100 nM
|
|
|
| 2 |
IC50 = 21500 nM
|
|
|
|
CP0204359
|
3-(1-(4-(pyridin-2-ylmethylamino)-1,3,5-triazin-2-yl)-1H-benzo[d]imidazol-2-ylamino)phenol
Show/Hide
|
C22H18N8O
|
2
|
| 1 |
IC50 = 2400 nM
|
|
|
| 2 |
IC50 > 25000 nM
|
|
|
|
CP0204361
|
3-(1-(4-amino-6-propyl-1,3,5-triazin-2-yl)-1H-benzo[d]imidazol-2-ylamino)phenol
Show/Hide
|
C19H19N7O
|
2
|
| 1 |
IC50 = 2640 nM
|
|
|
| 2 |
IC50 > 25000 nM
|
|
|
|
CP0314464
|
3-(1-(4-(2,2,2-trifluoroethylamino)-1,3,5-triazin-2-yl)-1H-benzo[d]imidazol-2-ylamino)phenol
Show/Hide
|
C18H14F3N7O
|
2
|
| 1 |
IC50 = 3200 nM
|
|
|
| 2 |
IC50 > 25000 nM
|
|
|
|
CP0287663
|
1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-N-(1H-1,2,4-triazol-3-yl)-1H-benzo[d]imidazol-2-amine
Show/Hide
|
C13H12N10
|
2
|
| 1 |
IC50 = 4600 nM
|
|
|
| 2 |
IC50 > 25000 nM
|
|
|
