Brief Information of the Compound and Protein
Compound Name
1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-N-(1-(difluoromethyl)-1H-pyrazol-3-yl)-1H-benzo[d]imidazol-2-amine
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PubChem ID
CID: 54584859
Canonical SMILES
Cc1nc(N)nc(n1)-n1c(Nc2ccn(n2)C(F)F)nc2ccccc12
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Compound Formula C15H13F2N9
Compound Structure
Protein Name
Serine/threonine-protein kinase mTOR
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
>
Atypical protein kinase FRAP subfamily
Uniprot ID
P42345
Gene Name
MTOR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000102 U-87MG ATCC Homo sapiens (Human)  2
1
IC50 = 770 nM
   TI
   LI
   LO
   TS
2
IC50 = 6500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 340 nM