Brief Information of the Compound and Protein
Compound Name
2-(4-(2-(3-hydroxyphenylamino)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazin-2-ylamino)acetonitrile
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PubChem ID
CID: 50990922
Canonical SMILES
Oc1cccc(Nc2nc3ccccc3n2-c2ncnc(NCC#N)n2)c1
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Compound Formula C18H14N8O
Compound Structure
Protein Name
Serine/threonine-protein kinase mTOR
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
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Atypical protein kinase FRAP subfamily
Uniprot ID
P42345
Gene Name
MTOR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000102 U-87MG ATCC Homo sapiens (Human)  2
1
IC50 = 700 nM
   TI
   LI
   LO
   TS
2
IC50 = 1700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 93 nM
2 IC50 = 97 nM