| Compound ID |
Compound Name |
Compound Formula |
|
CP0531526
|
US9428501, 58
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|
C32H36F3N7O2
|
1
|
| 1 |
IC50 = 0.55 nM
|
|
|
|
CP0512293
|
US9428501, 57
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|
C32H35F3N6O2
|
1
|
| 1 |
IC50 = 0.65 nM
|
|
|
|
CP0531492
|
US9428501, 18
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|
C33H37F3N6O2
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0512292
|
US9428501, 49
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|
C32H35F3N6O2
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0563775
|
US9428501, 69
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|
C34H39N7O2
|
1
|
| 1 |
IC50 = 3.2 nM
|
|
|
|
CP0488364
|
US9428501, 50
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|
C31H34F3N7O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0480786
|
US9428501, 44
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|
C33H37F3N6O2
|
1
|
| 1 |
IC50 = 4.2 nM
|
|
|
|
CP0518577
|
US9428501, 35
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|
C32H35F3N6O2
|
1
|
| 1 |
IC50 = 5.2 nM
|
|
|
|
CP0544276
|
US9428501, 66
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|
C34H39N7O2
|
1
|
| 1 |
IC50 = 6.2 nM
|
|
|
|
CP0492576
|
US9428501, 14
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|
C33H36F3N5O2
|
1
|
| 1 |
IC50 = 7.6 nM
|
|
|
|
CP0560878
|
US9428501, 79
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|
C33H37N7O2
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0562873
|
US9428501, 38
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|
C32H34F4N6O2
|
1
|
| 1 |
IC50 = 8.1 nM
|
|
|
|
CP0529407
|
US9428501, 19
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|
C33H37F3N6O2
|
1
|
| 1 |
IC50 = 8.5 nM
|
|
|
|
CP0492577
|
US9428501, 37
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|
C32H34F2N6O4
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
|
CP0544274
|
US9428501, 36
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|
C32H35F3N6O2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0516321
|
US9428501, 1
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|
C32H35F3N6O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0354016
|
(2S)-1-[[4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl]carbamoyl]pyrrolidine-2-carboxylic acid
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|
C19H21F3N4O3S
|
1
|
| 1 |
IC50 = 13.2 nM
|
|
|
|
CP0516320
|
US9428501, 23
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|
C32H35N7O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0252440
|
4-[2-[(1S)-1-[(2,6-diamino-5-cyanopyrimidin-4-yl)amino]ethyl]-7-fluoro-4-oxo-3-phenylquinolizin-1-yl]benzamide
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|
C29H23FN8O2
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0136524
|
2,4-diamino-6-[[(1S)-1-(7-fluoro-4-oxo-3-phenylquinolizin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
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|
C22H18FN7O
|
1
|
| 1 |
IC50 = 371 nM
|
|
|
|
CP0136523
|
2,4-diamino-6-[[(1S)-1-[7-fluoro-3-(4-fluorophenyl)-4-oxoquinolizin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
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|
C22H17F2N7O
|
1
|
| 1 |
IC50 = 384 nM
|
|
|
|
CP0242686
|
2-amino-4-[[(1S)-1-(7-fluoro-4-oxo-3-phenylquinolizin-2-yl)ethyl]amino]-6-methylpyrimidine-5-carbonitrile
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|
C23H19FN6O
|
1
|
| 1 |
IC50 = 826 nM
|
|
|
|
CP0256046
|
2,4-diamino-6-[[(1S)-1-(1-cyclopropyl-7-fluoro-4-oxo-3-phenylquinolizin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
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|
C25H22FN7O
|
1
|
| 1 |
IC50 = 980 nM
|
|
|
|
CP0952933
|
(S)-2-(1-((9H-Purin-6-yl)amino)ethyl)-6-methyl-3-phenyl-4H-quinolizin-4-one
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|
C23H20N6O
|
1
|
| 1 |
IC50 = 1156 nM
|
|
|
|
CP0219705
|
2-amino-4-[[(1S)-1-[7-fluoro-1-(4-fluorophenyl)-4-oxo-3-phenylquinolizin-2-yl]ethyl]amino]-6-methylpyrimidine-5-carbonitrile
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|
C29H22F2N6O
|
1
|
| 1 |
IC50 = 1844 nM
|
|
|
|
CP0549420
|
2,4-diamino-6-[[(1S)-1-(7-fluoro-4-oxo-1,3-diphenylquinolizin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
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|
C28H22FN7O
|
1
|
| 1 |
IC50 = 1918 nM
|
|
|
|
CP0484380
|
2,4-diamino-6-[[(1S)-1-(7-fluoro-1-methyl-4-oxo-3-phenylquinolizin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile
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|
C23H20FN7O
|
1
|
| 1 |
IC50 = 8297 nM
|
|
|
|
CP0142407
|
2,4-diamino-6-[[(1S)-1-[7-fluoro-3-(3-methylphenyl)-4-oxoquinolizin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile
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|
C23H20FN7O
|
1
|
| 1 |
IC50 > 2000 nM
|
|
|
