Brief Information of the Compound and Protein
Compound Name
2-amino-4-[[(1S)-1-[7-fluoro-1-(4-fluorophenyl)-4-oxo-3-phenylquinolizin-2-yl]ethyl]amino]-6-methylpyrimidine-5-carbonitrile
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PubChem ID
CID: 129262531
Canonical SMILES
C[C@H](Nc1nc(N)nc(C)c1C#N)c1c(-c2ccc(F)cc2)c2ccc(F)cn2c(=O)c1-c1ccccc1
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Compound Formula C29H22F2N6O
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42336
Gene Name
PIK3CA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000284 MDA-MB-453 Homo sapiens (Human)  1
1
IC50 = 1844 nM
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