| Compound ID |
Compound Name |
Compound Formula |
|
CP0528167
|
(R)-3-(4-fluorophenyl)-N-((R)-7-(piperidin-1-ylmethyl)-3,4-dihydro-2H-chromen-4-yl)-3-(3-(trifluoromethyl)phenylsulfonamido)propanamide
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|
C31H33F4N3O4S
|
2
|
| 1 |
IC50 = 0.8 nM
|
|
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| 2 |
Ki = 0.4 nM
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CP0409334
|
(R)-3-(naphthalene-7-sulfonamido)-3-phenyl-N-((R)-7-(piperidin-1-ylmethyl)-3,4-dihydro-2H-chromen-4-yl)propanamide
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|
C34H37N3O4S
|
3
|
| 1 |
IC50 = 3.4 nM
|
|
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| 2 |
Ki = 0.7 nM
|
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| 3 |
Ki = 0.77 nM
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CP0454187
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(R)-3-(3,4-dichlorophenylsulfonamido)-3-(4-fluorophenyl)-N-((R)-7-((2-methoxyethylamino)methyl)chroman-4-yl)propanamide
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|
C28H30Cl2FN3O5S
|
2
|
| 1 |
IC50 = 9.4 nM
|
|
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| 2 |
Ki = 6.7 nM
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CP0458794
|
(R)-N-((R)-7-((tert-butylamino)methyl)chroman-4-yl)-3-(3,4-dichlorophenylsulfonamido)-3-(4-fluorophenyl)propanamide
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|
C29H32Cl2FN3O4S
|
2
|
| 1 |
IC50 = 9.6 nM
|
|
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| 2 |
Ki = 5 nM
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CP0454188
|
(R)-N-((R)-7-((tert-butylamino)methyl)chroman-4-yl)-3-(4-fluorophenyl)-3-(3-(trifluoromethyl)phenylsulfonamido)-propanamide
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|
C30H33F4N3O4S
|
2
|
| 1 |
IC50 = 9.9 nM
|
|
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| 2 |
Ki = 4.8 nM
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CP0419970
|
(R)-N-((R)-7-((isobutylamino)methyl)chroman-4-yl)-3-(naphthalene-3-sulfonamido)-3-phenylpropanamide
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|
C33H37N3O4S
|
2
|
| 1 |
IC50 = 10.5 nM
|
|
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| 2 |
Ki = 5 nM
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CP0378638
|
(R)-N-((R)-7-(morpholinomethyl)chroman-4-yl)-3-(naphthalene-3-sulfonamido)-3-phenylpropanamide
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|
C33H35N3O5S
|
2
|
| 1 |
IC50 = 10.9 nM
|
|
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| 2 |
Ki = 3.7 nM
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CP0454177
|
(R)-3-(4-fluorophenyl)-N-((R)-7-((isobutylamino)methyl)chroman-4-yl)-3-(3-(trifluoromethyl)phenylsulfonamido)-propanamide
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|
C30H33F4N3O4S
|
2
|
| 1 |
IC50 = 14.8 nM
|
|
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| 2 |
Ki = 5.9 nM
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CP0520451
|
(R)-3-(naphthalene-3-sulfonamido)-3-phenyl-N-((R)-7-(pyrrolidin-1-ylmethyl)chroman-4-yl)propanamide
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|
C33H35N3O4S
|
2
|
| 1 |
IC50 = 14.8 nM
|
|
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| 2 |
Ki = 5.7 nM
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|
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CP0457737
|
(R)-N-((R)-7-((tert-butylamino)methyl)chroman-4-yl)-3-(naphthalene-3-sulfonamido)-3-phenylpropanamide
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|
C33H37N3O4S
|
2
|
| 1 |
IC50 = 17 nM
|
|
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| 2 |
Ki = 5.4 nM
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CP0441529
|
(R)-3-(4-fluorophenyl)-N-((R)-7-((2-methoxyethylamino)methyl)chroman-4-yl)-3-(3-(trifluoromethyl)phenylsulfonamido)-propanamide
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|
C29H31F4N3O5S
|
2
|
| 1 |
IC50 = 17.4 nM
|
|
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| 2 |
Ki = 14 nM
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CP0378627
|
(R)-3-(4-fluorophenyl)-N-((R)-7-(pyrrolidin-1-ylmethyl)chroman-4-yl)-3-(3-(trifluoromethyl)phenylsulfonamido)-propanamide
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|
C30H31F4N3O4S
|
2
|
| 1 |
IC50 = 19.7 nM
|
|
|
| 2 |
Ki = 5.5 nM
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CP0528209
|
(R)-3-(4-fluorophenyl)-N-((R)-7-((isopropylamino)methyl)-chroman-4-yl)-3-(3-(trifluoromethyl)phenylsulfonamido)-propanamide
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|
C29H31F4N3O4S
|
2
|
| 1 |
IC50 = 20.1 nM
|
|
|
| 2 |
Ki = 4.7 nM
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CP0457734
|
(R)-N-((R)-7-((tert-butylamino)methyl)chroman-4-yl)-3-(3,4-dichlorophenylsulfonamido)-3-phenylpropanamide
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|
C29H33Cl2N3O4S
|
2
|
| 1 |
IC50 = 24.3 nM
|
|
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| 2 |
Ki = 7.6 nM
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|
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CP0378631
|
(R)-N-((R)-7-((isopropylamino)methyl)chroman-4-yl)-3-(naphthalene-3-sulfonamido)-3-phenylpropanamide
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|
C32H35N3O4S
|
2
|
| 1 |
IC50 = 45.9 nM
|
|
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| 2 |
Ki = 8.3 nM
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CP0378632
|
(R)-N-((R)-7-((cyclobutylamino)methyl)chroman-4-yl)-3-(4-fluorophenyl)-3-(3-(trifluoromethyl)phenylsulfonamido)-propanamide
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|
C30H31F4N3O4S
|
2
|
| 1 |
IC50 = 46.2 nM
|
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| 2 |
Ki = 10 nM
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CP0502976
|
(R)-N-((R)-7-((ethylamino)methyl)chroman-4-yl)-3-(naphthalene-3-sulfonamido)-3-phenylpropanamide
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|
C31H33N3O4S
|
2
|
| 1 |
IC50 = 60.2 nM
|
|
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| 2 |
Ki = 8.9 nM
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CP0378635
|
(R)-N-((R)-7-((tert-butylamino)methyl)chroman-4-yl)-3-(4-tert-butylphenylsulfonamido)-3-phenylpropanamide
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|
C33H43N3O4S
|
2
|
| 1 |
IC50 = 60.9 nM
|
|
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| 2 |
Ki = 24.8 nM
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CP0454186
|
(R)-N-((R)-7-((cyclohexylamino)methyl)chroman-4-yl)-3-(naphthalene-3-sulfonamido)-3-phenylpropanamide
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|
C35H39N3O4S
|
2
|
| 1 |
IC50 = 69.9 nM
|
|
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| 2 |
Ki = 21.8 nM
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CP0457735
|
(R)-N-((R)-7-((tert-butylamino)methyl)chroman-4-yl)-3-phenyl-3-(3-(trifluoromethyl)phenylsulfonamido)propanamide
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|
C30H34F3N3O4S
|
2
|
| 1 |
IC50 = 78.4 nM
|
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| 2 |
Ki = 17.9 nM
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CP0457736
|
(R)-N-((R)-7-(((2R,6S)-2,6-dimethylpiperidin-1-yl)methyl)-chroman-4-yl)-3-(naphthalene-3-sulfonamido)-3-phenylpropanamide
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|
C36H41N3O4S
|
2
|
| 1 |
IC50 = 96.3 nM
|
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| 2 |
Ki = 13.4 nM
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CP0378637
|
(3R)-N-[(4R)-7-[(tert-butylamino)methyl]-3,4-dihydro-2H-chromen-4-yl]-3-[(3-chlorophenyl)sulfonylamino]-3-phenylpropanamide
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|
C29H34ClN3O4S
|
2
|
| 1 |
IC50 = 113 nM
|
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| 2 |
Ki = 27.7 nM
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CP0378633
|
(R)-N-((R)-7-((tert-butylamino)methyl)chroman-4-yl)-3-(5-chloro-2,4-difluorophenylsulfonamido)-3-phenylpropanamide
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|
C29H32ClF2N3O4S
|
2
|
| 1 |
IC50 = 127 nM
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| 2 |
Ki = 20.6 nM
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CP0378629
|
(R)-N-((R)-7-((dimethylamino)methyl)chroman-4-yl)-3-(naphthalene-3-sulfonamido)-3-phenylpropanamide
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|
C31H33N3O4S
|
2
|
| 1 |
IC50 = 167 nM
|
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| 2 |
Ki = 84.8 nM
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CP0378634
|
(R)-N-((R)-7-((tert-butylamino)methyl)chroman-4-yl)-3-(3-chloro-4-fluorophenylsulfonamido)-3-phenylpropanamide
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|
C29H33ClFN3O4S
|
2
|
| 1 |
IC50 = 203 nM
|
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| 2 |
Ki = 25.2 nM
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CP0524333
|
(R)-N-((R)-7-((tert-butylamino)methyl)chroman-4-yl)-3-(3-chloro-2-methylphenylsulfonamido)-3-phenylpropanamide
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|
C30H36ClN3O4S
|
2
|
| 1 |
IC50 = 207 nM
|
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| 2 |
Ki = 40.6 nM
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CP0419971
|
(R)-N-((R)-7-((methylamino)methyl)chroman-4-yl)-3-(naphthalene-3-sulfonamido)-3-phenylpropanamide
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|
C30H31N3O4S
|
2
|
| 1 |
IC50 = 212 nM
|
|
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| 2 |
Ki = 138 nM
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CP0386051
|
(R)-N-((R)-7-((tert-butylamino)methyl)chroman-4-yl)-3-(2,4-dichlorophenylsulfonamido)-3-phenylpropanamide
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|
C29H33Cl2N3O4S
|
2
|
| 1 |
IC50 = 255 nM
|
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| 2 |
Ki = 127 nM
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CP0378628
|
(R)-N-((R)-7-((tert-butylamino)methyl)chroman-4-yl)-3-phenyl-3-(4-(trifluoromethyl)phenylsulfonamido)propanamide
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|
C30H34F3N3O4S
|
2
|
| 1 |
IC50 = 330 nM
|
|
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| 2 |
Ki = 77.6 nM
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CP0386052
|
(R)-N-((R)-7-(aminomethyl)chroman-4-yl)-3-(naphthalene-3-sulfonamido)-3-phenylpropanamide
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|
C29H29N3O4S
|
2
|
| 1 |
IC50 = 352 nM
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| 2 |
Ki = 308 nM
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CP0441534
|
(R)-N-((R)-7-((tert-butylamino)methyl)chroman-4-yl)-3-(4-cyanophenyl)-3-(3-(trifluoromethyl)phenylsulfonamido)-propanamide
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|
C31H33F3N4O4S
|
2
|
| 1 |
IC50 = 566.2 nM
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| 2 |
Ki = 120 nM
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CP0378636
|
(R)-N-((R)-7-((tert-butylamino)methyl)chroman-4-yl)-3-(4-chlorophenylsulfonamido)-3-phenylpropanamide
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|
C29H34ClN3O4S
|
2
|
| 1 |
IC50 = 580 nM
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| 2 |
Ki = 132 nM
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CP0492851
|
(R)-N-((R)-7-((tert-butylamino)methyl)chroman-4-yl)-3-phenyl-3-(2-(trifluoromethyl)phenylsulfonamido)propanamide
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|
C30H34F3N3O4S
|
2
|
| 1 |
IC50 = 2000 nM
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| 2 |
Ki = 367 nM
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CP0458795
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(R)-N-((R)-7-((tert-butylamino)methyl)chroman-4-yl)-3-(2-chlorophenylsulfonamido)-3-phenylpropanamide
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|
C29H34ClN3O4S
|
2
|
| 1 |
IC50 = 2030 nM
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| 2 |
Ki = 393 nM
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CP0419974
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(R)-N-((R)-7-(hydroxymethyl)chroman-4-yl)-3-(naphthalene-3-sulfonamido)-3-phenylpropanamide
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|
C29H28N2O5S
|
2
|
| 1 |
IC50 > 4000 nM
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| 2 |
Ki > 50000 nM
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CP0409335
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(R)-3-(naphthalene-3-sulfonamido)-3-phenyl-N-((R)-6-(piperidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl)propanamide
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|
C35H39N3O3S
|
1
|
| 1 |
Ki = 0.24 nM
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CP0462797
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(R)-3-(naphthalene-7-sulfonamido)-3-phenyl-N-((R)-7-(piperidin-1-ylmethyl)-2,2-dioxo-1,2,3,4-tetrahydro-1-methyl-2,1-benzothiazine-4-yl)propanamide
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|
C34H38N4O5S2
|
1
|
| 1 |
Ki = 1.3 nM
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CP0503902
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(R)-3-(naphthalene-7-sulfonamido)-3-phenyl-N-((R)-5-(piperidin-1-ylmethyl)-2,3-dihydro-1H-inden-1-yl)propanamide
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|
C34H37N3O3S
|
1
|
| 1 |
Ki = 1.6 nM
|
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CP0503903
|
(R)-3-(naphthalene-7-sulfonamido)-3-phenyl-N-((S)-7-(piperidin-1-ylmethyl)-2,2-dioxo-1,2,3,4-tetrahydro-1-methyl-2,1-benzothiazine-4-yl)propanamide
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|
C34H38N4O5S2
|
1
|
| 1 |
Ki = 15.8 nM
|
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CP0442283
|
(R)-3-(naphthalene-3-sulfonamido)-3-phenyl-N-((R)-1-(4-(piperidin-1-ylmethyl)phenyl)ethyl)propanamide
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|
C33H37N3O3S
|
1
|
| 1 |
Ki = 17 nM
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CP0461556
|
(R)-3-(naphthalene-7-sulfonamido)-3-phenyl-N-((S)-7-(piperidin-1-ylmethyl)chroman-4-yl)propanamide
Show/Hide
|
C34H37N3O4S
|
1
|
| 1 |
Ki = 17 nM
|
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CP0466971
|
(R)-3-(naphthalene-7-sulfonamido)-3-phenyl-N-((S)-6-(piperidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl)propanamide
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|
C35H39N3O3S
|
1
|
| 1 |
Ki = 31 nM
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CP0442288
|
(R)-N-(4-(piperidin-1-ylmethyl)benzyl)-3-(naphthalene-7-sulfonamido)-3-phenylpropanamide
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|
C32H35N3O3S
|
1
|
| 1 |
Ki = 132 nM
|
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CP0523737
|
(S)-3-(naphthalene-7-sulfonamido)-3-phenyl-N-((R)-7-(piperidin-1-ylmethyl)chroman-4-yl)propanamide
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|
C34H37N3O4S
|
1
|
| 1 |
Ki = 143 nM
|
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CP0442289
|
3-(RS)-N-(4-(piperidin-1-ylmethyl)benzyl)-3-(naphthalene-7-sulfonamido)-3-phenylpropanamide
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|
C32H35N3O3S
|
1
|
| 1 |
Ki = 382 nM
|
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CP0462799
|
(S)-3-(naphthalene-7-sulfonamido)-3-phenyl-N-((S)-7-(piperidin-1-ylmethyl)chroman-4-yl)propanamide
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|
C34H37N3O4S
|
1
|
| 1 |
Ki = 1900 nM
|
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