| Compound ID |
Compound Name |
Compound Formula |
|
CP0666580
|
Dimethyl-(tetrahydro-pyran-4-yl)-{4-[(3-p-tolyl-8,9-dihydro-7H-benzocycloheptene-6-carbonyl)-amino]-benzyl}-ammonium chloride(TAK-779)
Show/Hide
|
C33H39ClN2O2
|
1
|
| 1 |
IC50 = 0.95 nM
|
|
|
|
CP0433403
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-cyclopropyl-4-spiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-ylbutanamide
Show/Hide
|
C29H32F6N2O2
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0433402
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(4-fluorophenyl)-4-spiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-ylbutanamide
Show/Hide
|
C32H31F7N2O2
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0355486
|
N-[4-[[methyl(oxan-4-yl)amino]methyl]phenyl]-7-(4-methylphenyl)-2-(2-methylpropyl)-1-oxo-3H-2-benzazepine-4-carboxamide
Show/Hide
|
C35H41N3O3
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0431450
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(4-fluorophenyl)-4-(6-methoxyspiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-yl)butanamide
Show/Hide
|
C33H33F7N2O3
|
1
|
| 1 |
IC50 = 163 nM
|
|
|
|
CP0433404
|
2-(4-fluorophenyl)-N-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-4-spiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-ylbutanamide
Show/Hide
|
C31H31F5N2O2
|
1
|
| 1 |
IC50 = 173 nM
|
|
|
|
CP0494799
|
N-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-4-spiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-ylbutanamide
Show/Hide
|
C25H28F4N2O2
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0385865
|
N-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-4-(6-methoxyspiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-yl)butanamide
Show/Hide
|
C26H30F4N2O3
|
1
|
| 1 |
IC50 = 318 nM
|
|
|
|
CP0415033
|
2-(4-fluorophenyl)-N-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-4-(6-methoxyspiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-yl)butanamide
Show/Hide
|
C32H33F5N2O3
|
1
|
| 1 |
IC50 = 353 nM
|
|
|
|
CP0376513
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(4-fluorophenyl)-4-(3-methylspiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-yl)butanamide
Show/Hide
|
C33H33F7N2O2
|
1
|
| 1 |
IC50 = 462 nM
|
|
|
|
CP0494800
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-4-spiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-ylbutanamide
Show/Hide
|
C26H28F6N2O2
|
1
|
| 1 |
IC50 = 684 nM
|
|
|
|
CP0433401
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-4-(6-methoxyspiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-yl)butanamide
Show/Hide
|
C27H30F6N2O3
|
1
|
| 1 |
IC50 = 1240 nM
|
|
|
|
CP0415035
|
2-(4-fluorophenyl)-N-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-4-(3-methylspiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-yl)butanamide
Show/Hide
|
C32H33F5N2O2
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0231889
|
N-[4-[[methyl(oxan-4-yl)amino]methyl]phenyl]-8-(4-methylphenyl)-2-(2-methylpropyl)-1-oxo-3H-2-benzazepine-4-carboxamide
Show/Hide
|
C35H41N3O3
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0415034
|
2-(4-fluorophenyl)-N-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-4-(6-hydroxyspiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-yl)butanamide
Show/Hide
|
C31H31F5N2O3
|
1
|
| 1 |
IC50 = 6100 nM
|
|
|
|
CP0448948
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-4-(3-methylspiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-yl)butanamide
Show/Hide
|
C27H30F6N2O2
|
1
|
| 1 |
IC50 = 7540 nM
|
|
|
|
CP0494796
|
N-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-4-(3-methylspiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-yl)butanamide
Show/Hide
|
C26H30F4N2O2
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
