Brief Information of the Compound and Protein
Compound Name
N-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-4-(6-methoxyspiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-yl)butanamide
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PubChem ID
CID: 122181149
Canonical SMILES
COc1ccc2c(CCOC22CCN(CCCC(=O)NCc3cc(F)cc(c3)C(F)(F)F)CC2)c1
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Compound Formula C26H30F4N2O3
Compound Structure
Protein Name
C-C chemokine receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P41597
Gene Name
CCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000064 Chem-1 Rattus norvegicus (Rat)  1
1
IC50 = 318 nM
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