Brief Information of the Cell Line and Protein
Cell Line ID: CL000043 , U2OS
 Cell Line Info 
Synonyms
U-2 OS
U-2OS
U-2-OS
U2-OS
U20-S
U20S
2T
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0042
Protein ID: PT01018 , Thyroid hormone receptor beta
 Protein Info 
Gene Name THRB
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P10828
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000043
 Cell Line Info 
 Protein ID: PT01018
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0026502
 Compound Info 
(2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid
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C15H12I3NO4
  1
1
EC50 = 11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0646460
 Compound Info 
5-(4-(4-hydroxy-3-isopropylphenoxy)-3,5-diiodobenzyl)imidazolidine-2,4-dione
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C19H18I2N2O4
  1
1
EC50 = 390 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0843267
 Compound Info 
5-(3,5-dibromo-4-(4-hydroxy-3-isopropylphenoxy)benzyl)imidazolidine-2,4-dione
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C19H18Br2N2O4
  1
1
EC50 = 421 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0823542
 Compound Info 
5-(4-(3-ethyl-4-hydroxyphenoxy)-3,5-diiodobenzyl)imidazolidine-2,4-dione
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C18H16I2N2O4
  1
1
EC50 = 1400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0733970
 Compound Info 
5-(4-(3-cyclopropyl-4-hydroxyphenoxy)-3,5-diiodobenzyl)imidazolidine-2,4-dione
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C19H16I2N2O4
  1
1
EC50 = 2000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0748742
 Compound Info 
5-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodobenzyl)imidazolidine-2,4-dione
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C16H11I3N2O4
  1
1
EC50 = 2000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0647090
 Compound Info 
5-(4-(4-hydroxy-3-methylphenoxy)-3,5-diiodobenzyl)imidazolidine-2,4-dione
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C17H14I2N2O4
  1
1
EC50 = 4000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0647089
 Compound Info 
5-(4-(4-hydroxy-3-bromophenoxy)-3,5-diiodobenzyl)imidazolidine-2,4-dione
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C16H11BrI2N2O4
  1
1
EC50 = 5200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0700404
 Compound Info 
5-(4-(4-hydroxy-3-methoxyphenoxy)-3,5-diiodobenzyl)imidazolidine-2,4-dione
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C17H14I2N2O5
  1
1
EC50 = 8000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0893813
 Compound Info 
5-(4-(4-hydroxyphenoxy)-3,5-diiodobenzyl)imidazolidine-2,4-dione
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C16H12I2N2O4
  1
1
EC50 > 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS