Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-(4-(3-ethyl-4-hydroxyphenoxy)-3,5-diiodobenzyl)imidazolidine-2,4-dione
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 PubChem ID
CID: 44452419
Canonical SMILES
CCc1cc(Oc2c(I)cc(CC3NC(=O)NC3=O)cc2I)ccc1O
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Compound Formula C18H16I2N2O4
Compound Structure
Protein Name
 Protein Info 
Thyroid hormone receptor beta
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group A
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Nuclear hormone receptor subfamily 1 group A member 2
Uniprot ID
P10828
Gene Name
THRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 27 nM
   TI
   LI
   LO
   TS
CL000043 U2OS
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 1400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 18 nM