| Compound ID |
Compound Name |
Compound Formula |
|
CP0005428
|
Duvelisib
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|
C22H17ClN6O
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
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CP0007933
|
2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-1H-benzimidazole
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|
C19H21F2N7O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
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CP0460944
|
2-[4-[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]piperazin-1-yl]-1-[(2R)-pyrrolidin-2-yl]ethanone
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|
C25H31F2N9O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
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CP0460946
|
5-fluoro-3-phenyl-2-[(1R)-1-(7H-purin-6-ylamino)propyl]quinazolin-4-one
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|
C22H18FN7O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0563574
|
1-[4-[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]piperazin-1-yl]-2-[(2S)-pyrrolidin-2-yl]ethanone
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|
C25H31F2N9O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0451483
|
[4-[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]piperazin-1-yl]-[(2R)-pyrrolidin-2-yl]methanone
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|
C24H29F2N9O2
|
2
|
| 1 |
IC50 = 9 nM
|
|
|
| 2 |
IC50 = 12 nM
|
|
|
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CP0548793
|
[4-[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]piperazin-1-yl]-[(2S)-piperidin-2-yl]methanone
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|
C25H31F2N9O2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0568464
|
[4-[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]piperazin-1-yl]-[(2R)-piperidin-2-yl]methanone
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|
C25H31F2N9O2
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
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CP0460945
|
(3S)-N-(2-amino-2-oxoethyl)-1-[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]piperidine-3-carboxamide
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|
C23H27F2N9O3
|
1
|
| 1 |
IC50 = 95 nM
|
|
|
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CP0386176
|
4-[4-[2-(difluoromethyl)-6-methoxybenzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]morpholine
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|
C20H23F2N7O3
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0414296
|
2-amino-1-[4-[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]piperidin-1-yl]ethanone
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|
C22H26F2N8O2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0418043
|
4-[4-morpholin-4-yl-6-(2-propan-2-ylbenzimidazol-1-yl)-1,3,5-triazin-2-yl]morpholine
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|
C21H27N7O2
|
1
|
| 1 |
IC50 = 128 nM
|
|
|
|
CP0553527
|
N-(2-amino-2-oxoethyl)-1-[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]piperidine-4-carboxamide
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|
C23H27F2N9O3
|
1
|
| 1 |
IC50 = 171 nM
|
|
|
|
CP0386175
|
4-[4-(2-methylbenzimidazol-1-yl)-6-morpholin-4-yl-1,3,5-triazin-2-yl]morpholine
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|
C19H23N7O2
|
1
|
| 1 |
IC50 = 187 nM
|
|
|
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CP0414295
|
[4-[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]piperazin-1-yl]-piperidin-4-ylmethanone
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|
C25H31F2N9O2
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0386172
|
4-[4-(6-methoxy-2-propan-2-ylbenzimidazol-1-yl)-6-morpholin-4-yl-1,3,5-triazin-2-yl]morpholine
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|
C22H29N7O3
|
1
|
| 1 |
IC50 = 423 nM
|
|
|
|
CP0473835
|
4-[4-(6-methoxy-2-methylbenzimidazol-1-yl)-6-morpholin-4-yl-1,3,5-triazin-2-yl]morpholine
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|
C20H25N7O3
|
1
|
| 1 |
IC50 = 458 nM
|
|
|
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CP0002420
|
2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
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|
C19H17NO3
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0570284
|
2,4-diamino-6-[(2S,5S)-2-[3-(3-fluorophenyl)-5-(5-methoxypyridin-3-yl)-4-oxoquinazolin-2-yl]-5-methylpyrrolidin-1-yl]pyrimidine-5-carbonitrile
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|
C30H26FN9O2
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0395810
|
(2R)-2-amino-1-[4-[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]piperidin-1-yl]propan-1-one
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|
C23H28F2N8O2
|
1
|
| 1 |
IC50 = 740 nM
|
|
|
|
CP0433684
|
6-methoxy-3-(5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl)quinolin-2(1H)-one
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|
C19H15N3O4
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0395849
|
2-[1-[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]piperidin-4-yl]ethanamine
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|
C22H28F2N8O
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
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CP0568018
|
2,4-diamino-6-[(2S,5S)-2-(5-chloro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-5-methylpyrrolidin-1-yl]pyrimidine-5-carbonitrile
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|
C23H20ClN9O
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
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CP0455020
|
(2S)-2-amino-1-[4-[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]piperidin-1-yl]propan-1-one
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|
C23H28F2N8O2
|
1
|
| 1 |
IC50 = 1090 nM
|
|
|
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CP0386174
|
4-[4-(5-methoxy-2-propan-2-ylbenzimidazol-1-yl)-6-morpholin-4-yl-1,3,5-triazin-2-yl]morpholine
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|
C22H29N7O3
|
1
|
| 1 |
IC50 = 1120 nM
|
|
|
|
CP0549685
|
N-[(2R)-1-amino-1-oxopropan-2-yl]-1-[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]piperidine-4-carboxamide
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|
C24H29F2N9O3
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
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CP0567847
|
2,4-diamino-6-[(2S,5S)-2-[5-chloro-3-(3-fluorophenyl)-4-oxoquinazolin-2-yl]-5-methylpyrrolidin-1-yl]pyrimidine-5-carbonitrile
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|
C24H20ClFN8O
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0386173
|
4-[4-(5-methoxy-2-methylbenzimidazol-1-yl)-6-morpholin-4-yl-1,3,5-triazin-2-yl]morpholine
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|
C20H25N7O3
|
1
|
| 1 |
IC50 = 2770 nM
|
|
|
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CP0420003
|
(3S)-3-amino-1-[4-[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]piperazin-1-yl]-4-phenylbutan-1-one
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|
C29H33F2N9O2
|
1
|
| 1 |
IC50 = 2841 nM
|
|
|
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CP0544188
|
2,4-diamino-6-[(2S,5S)-2-(6,8-difluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-5-methylpyrrolidin-1-yl]pyrimidine-5-carbonitrile
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|
C23H19F2N9O
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
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CP0375548
|
3-(benzo[d]thiazol-2-yl)-7-hydroxy-2H-chromen-2-one
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|
C16H9NO3S
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
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CP0406291
|
(3S)-3-amino-1-[4-[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]piperazin-1-yl]-5-methylhexan-1-one
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|
C26H35F2N9O2
|
1
|
| 1 |
IC50 = 9100 nM
|
|
|
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CP0454691
|
(3S)-3-amino-1-[4-[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]piperazin-1-yl]-3-phenylpropan-1-one
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|
C28H31F2N9O2
|
1
|
| 1 |
IC50 = 17000 nM
|
|
|
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CP0562605
|
4-[(2S,3aS,7aS)-2-[5-chloro-3-(3-fluorophenyl)-4-oxoquinazolin-2-yl]-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-2,6-diaminopyrimidine-5-carbonitrile
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|
C27H24ClFN8O
|
1
|
| 1 |
IC50 = 28000 nM
|
|
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CP0544187
|
4-[(2S,3aS,7aS)-2-(5-chloro-3-morpholin-4-yl-4-oxoquinazolin-2-yl)-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-2,6-diaminopyrimidine-5-carbonitrile
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|
C25H28ClN9O2
|
1
|
| 1 |
IC50 = 41000 nM
|
|
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CP0570818
|
4-[(2S,3aS,7aS)-2-(5-fluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-2,6-diaminopyrimidine-5-carbonitrile
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|
C26H24FN9O
|
1
|
| 1 |
IC50 = 42000 nM
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CP0373900
|
1,7-dimethyl-1H-pyrazolo[3,4-b]quinolin-3-yl 2-phenoxyacetate
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|
C20H17N3O3
|
1
|
| 1 |
IC50 = 47000 nM
|
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CP0296638
|
methyl 5-[(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)sulfanylmethyl]furan-2-carboxylate
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|
C15H14N2O3S2
|
1
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| 1 |
IC50 > 100000 nM
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CP0400330
|
3-(6-chloro-2-oxobenzo[d]oxazol-3(2H)-yl)-N-phenylpropanamide
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|
C16H13ClN2O3
|
1
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| 1 |
IC50 > 100000 nM
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CP0425759
|
4-[4-[2-(difluoromethyl)-5-methoxybenzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]morpholine
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|
C20H23F2N7O3
|
1
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| 1 |
IC50 > 1000 nM
|
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