| Compound ID |
Compound Name |
Compound Formula |
|
CP0140793
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[3-[1-[(4-fluorophenyl)methyl]piperidin-4-yl]propoxy]-1,3-thiazole-5-carboxamide
Show/Hide
|
C28H32FN5O3S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0225239
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[1-[(2,6-difluorophenyl)methyl]piperidin-4-yl]ethoxy]-1,3-thiazole-5-carboxamide
Show/Hide
|
C27H29F2N5O3S
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0558215
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-N-methyl-4-[[1-[(3-nitrophenyl)methyl]piperidin-4-yl]methoxy]-1,3-thiazole-5-carboxamide
Show/Hide
|
C27H30N6O5S
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0219125
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[1-(1,2,3,4-tetrahydroacridin-9-yl)triazol-4-yl]ethoxy]-1,3-thiazole-5-carboxamide
Show/Hide
|
C30H28N8O3S
|
1
|
| 1 |
IC50 = 6.5 nM
|
|
|
|
CP0495532
|
4-(1-benzylpiperidin-4-yl)oxy-2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C26H29N5O3S
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0483865
|
4-[3-(1-benzylpiperidin-4-yl)propoxy]-2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-1,3-thiazole-5-carboxamide
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|
C28H33N5O3S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0274102
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[3-[1-[(3-fluorophenyl)methyl]piperidin-4-yl]propoxy]-1,3-thiazole-5-carboxamide
Show/Hide
|
C28H32FN5O3S
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0558272
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[1-[(3,4-difluorophenyl)methyl]piperidin-4-yl]ethoxy]-1,3-thiazole-5-carboxamide
Show/Hide
|
C27H29F2N5O3S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0352700
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-hydroxy-1,3-thiazole-5-carboxamide
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|
C13H12N4O3S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0349316
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[[1-[(2-fluorophenyl)methyl]piperidin-4-yl]methoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C27H30FN5O3S
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0219128
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[3-[1-[2-[(7-methoxy-1,2,3,4-tetrahydroacridin-9-yl)amino]ethyl]triazol-4-yl]propoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C35H39N9O4S
|
1
|
| 1 |
IC50 = 14.6 nM
|
|
|
|
CP0532243
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[3-[1-[(2-fluorophenyl)methyl]piperidin-4-yl]propoxy]-1,3-thiazole-5-carboxamide
Show/Hide
|
C28H32FN5O3S
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0274100
|
4-[(1-benzylpiperidin-4-yl)methoxy]-2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C27H31N5O3S
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0219130
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-methoxy-1,3-thiazole-5-carboxamide
Show/Hide
|
C14H14N4O3S
|
1
|
| 1 |
IC50 = 17.2 nM
|
|
|
|
CP0140788
|
4-[2-(1-benzylpiperidin-4-yl)ethoxy]-2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-1,3-thiazole-5-carboxamide
Show/Hide
|
C27H31N5O3S
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0546155
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[3-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]prop-2-ynoxy]ethoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C32H28N6O8S
|
1
|
| 1 |
IC50 = 19.7 nM
|
|
|
|
CP0016685
|
3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione
Show/Hide
|
C19H12Cl2N2O2
|
2
|
| 1 |
IC50 = 19.8 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
|
CP0363574
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-N-methyl-4-[2-[[1-[2-(1,2,3,4-tetrahydroacridin-9-ylamino)ethyl]triazol-4-yl]methoxy]ethoxy]-1,3-thiazole-5-carboxamide
Show/Hide
|
C34H37N9O4S
|
1
|
| 1 |
IC50 = 20.8 nM
|
|
|
|
CP0219111
|
4-(cyclopropylmethoxy)-N-methyl-2-[2-[[2-[2-(1,2,3,4-tetrahydroacridin-9-ylamino)ethylamino]acetyl]amino]pyridin-4-yl]-1,3-thiazole-5-carboxamide
Show/Hide
|
C31H35N7O3S
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0569287
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[8-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyoctoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C35H38N6O8S
|
1
|
| 1 |
IC50 = 23.8 nM
|
|
|
|
CP0225242
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[1-[(3-fluorophenyl)methyl]piperidin-4-yl]ethoxy]-1,3-thiazole-5-carboxamide
Show/Hide
|
C27H30FN5O3S
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0495533
|
4-[[1-[(4-bromophenyl)methyl]piperidin-4-yl]methoxy]-2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C27H30BrN5O3S
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0219129
|
4-[2-[[1-[2-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]ethyl]triazol-4-yl]methoxy]ethoxy]-2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C34H36ClN9O4S
|
1
|
| 1 |
IC50 = 26.3 nM
|
|
|
|
CP0251448
|
4-[2-[1-[(2-chlorophenyl)methyl]piperidin-4-yl]ethoxy]-2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-1,3-thiazole-5-carboxamide
Show/Hide
|
C27H30ClN5O3S
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0553277
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[3-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]prop-2-ynoxy]ethoxy]-1,3-thiazole-5-carboxamide
Show/Hide
|
C31H26N6O8S
|
1
|
| 1 |
IC50 = 27.7 nM
|
|
|
|
CP0571383
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[[1-[2-[(7-methoxy-1,2,3,4-tetrahydroacridin-9-yl)amino]ethyl]triazol-4-yl]methoxy]ethoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C35H39N9O5S
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0361727
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[1-[2-[(7-methoxy-1,2,3,4-tetrahydroacridin-9-yl)amino]ethyl]triazol-4-yl]ethoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C34H37N9O4S
|
1
|
| 1 |
IC50 = 37.1 nM
|
|
|
|
CP0225240
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[1-[(4-fluorophenyl)methyl]piperidin-4-yl]ethoxy]-1,3-thiazole-5-carboxamide
Show/Hide
|
C27H30FN5O3S
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0264580
|
4-(cyclopropylmethoxy)-2-[2-[[2-[2-[(7-methoxy-1,2,3,4-tetrahydroacridin-9-yl)amino]ethylamino]acetyl]amino]pyridin-4-yl]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C32H37N7O4S
|
1
|
| 1 |
IC50 = 39.3 nM
|
|
|
|
CP0483864
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[[1-[(3,4-dichlorophenyl)methyl]piperidin-4-yl]methoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C27H29Cl2N5O3S
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0570072
|
4-methoxy-N-methyl-2-[2-[[2-[2-(1,2,3,4-tetrahydroacridin-9-ylamino)ethylamino]acetyl]amino]pyridin-4-yl]-1,3-thiazole-5-carboxamide
Show/Hide
|
C28H31N7O3S
|
1
|
| 1 |
IC50 = 41.1 nM
|
|
|
|
CP0190505
|
4-(cyclopropylmethoxy)-N-methyl-2-[2-[[2-[4-(1,2,3,4-tetrahydroacridin-9-ylamino)butylamino]acetyl]amino]pyridin-4-yl]-1,3-thiazole-5-carboxamide
Show/Hide
|
C33H39N7O3S
|
1
|
| 1 |
IC50 = 41.6 nM
|
|
|
|
CP0219131
|
4-(cyclopropylmethoxy)-2-[2-[[2-[2-(1,2,3,4-tetrahydroacridin-9-ylamino)ethylamino]acetyl]amino]pyridin-4-yl]-1,3-thiazole-5-carboxamide
Show/Hide
|
C30H33N7O3S
|
1
|
| 1 |
IC50 = 42.6 nM
|
|
|
|
CP0274096
|
4-[[1-[(4-chlorophenyl)methyl]piperidin-4-yl]methoxy]-2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C27H30ClN5O3S
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0361730
|
4-[2-[1-[2-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]ethyl]triazol-4-yl]ethoxy]-2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C33H34ClN9O3S
|
1
|
| 1 |
IC50 = 46.7 nM
|
|
|
|
CP0538787
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[2-[2-[4-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxymethyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C36H37N9O10S
|
1
|
| 1 |
IC50 = 46.9 nM
|
|
|
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CP0469259
|
4-[[1-[(3-bromophenyl)methyl]piperidin-4-yl]methoxy]-2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C27H30BrN5O3S
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0553276
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[3-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-4-yl]prop-2-ynoxy]ethoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C32H30N6O7S
|
1
|
| 1 |
IC50 = 49.2 nM
|
|
|
|
CP0190507
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-N-methyl-4-[2-[1-(1,2,3,4-tetrahydroacridin-9-yl)triazol-4-yl]ethoxy]-1,3-thiazole-5-carboxamide
Show/Hide
|
C31H30N8O3S
|
1
|
| 1 |
IC50 = 51.7 nM
|
|
|
|
CP0274098
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[[1-[(3,4-difluorophenyl)methyl]piperidin-4-yl]methoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C27H29F2N5O3S
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0537018
|
4-(cyclopropylmethoxy)-N-methyl-2-[2-[[2-[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexylamino]acetyl]amino]pyridin-4-yl]-1,3-thiazole-5-carboxamide
Show/Hide
|
C35H43N7O3S
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0264596
|
4-(cyclopropylmethoxy)-N-methyl-2-[2-[[2-[8-(1,2,3,4-tetrahydroacridin-9-ylamino)octylamino]acetyl]amino]pyridin-4-yl]-1,3-thiazole-5-carboxamide
Show/Hide
|
C37H47N7O3S
|
1
|
| 1 |
IC50 = 62.2 nM
|
|
|
|
CP0264579
|
2-[2-[[2-[2-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]ethylamino]acetyl]amino]pyridin-4-yl]-4-(cyclopropylmethoxy)-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C31H34ClN7O3S
|
1
|
| 1 |
IC50 = 62.6 nM
|
|
|
|
CP0569286
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[3-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-4-yl]prop-2-ynoxy]ethoxy]-1,3-thiazole-5-carboxamide
Show/Hide
|
C31H28N6O7S
|
1
|
| 1 |
IC50 = 63.8 nM
|
|
|
|
CP0190504
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-N-methyl-4-[3-[1-[2-(1,2,3,4-tetrahydroacridin-9-ylamino)ethyl]triazol-4-yl]propoxy]-1,3-thiazole-5-carboxamide
Show/Hide
|
C34H37N9O3S
|
1
|
| 1 |
IC50 = 64.3 nM
|
|
|
|
CP0538090
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[2-[2-[2-[2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C37H42N6O12S
|
1
|
| 1 |
IC50 = 69.3 nM
|
|
|
|
CP0538788
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[10-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxydecoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C37H42N6O8S
|
1
|
| 1 |
IC50 = 70.4 nM
|
|
|
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CP0361728
|
N-methyl-4-propan-2-yloxy-2-[2-[[2-[2-(1,2,3,4-tetrahydroacridin-9-ylamino)ethylamino]acetyl]amino]pyridin-4-yl]-1,3-thiazole-5-carboxamide
Show/Hide
|
C30H35N7O3S
|
1
|
| 1 |
IC50 = 71.6 nM
|
|
|
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CP0564136
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[6-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyhexoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C33H34N6O8S
|
1
|
| 1 |
IC50 = 71.6 nM
|
|
|
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CP0219127
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-N-methyl-4-[2-[1-[2-(1,2,3,4-tetrahydroacridin-9-ylamino)ethyl]triazol-4-yl]ethoxy]-1,3-thiazole-5-carboxamide
Show/Hide
|
C33H35N9O3S
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
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CP0466305
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[2-[2-[2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyethoxy]ethoxy]ethoxy]ethoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C35H38N6O11S
|
1
|
| 1 |
IC50 = 73.2 nM
|
|
|
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CP0564135
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[5-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]pent-4-ynoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C32H28N6O7S
|
1
|
| 1 |
IC50 = 79.1 nM
|
|
|
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CP0466304
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[2-[2-[2-[4-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxymethyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C38H41N9O11S
|
1
|
| 1 |
IC50 = 79.5 nM
|
|
|
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CP0264578
|
2-[2-(cyclobutanecarbonylamino)pyridin-4-yl]-4-(cyclopropylmethoxy)-N-[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]-1,3-thiazole-5-carboxamide
Show/Hide
|
C34H38N6O3S
|
1
|
| 1 |
IC50 = 80.7 nM
|
|
|
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CP0143396
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[8-[4-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxymethyl]triazol-1-yl]octoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C38H41N9O8S
|
1
|
| 1 |
IC50 = 83.1 nM
|
|
|
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CP0301337
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-N-methyl-4-[2-[[1-(1,2,3,4-tetrahydroacridin-9-yl)triazol-4-yl]methoxy]ethoxy]-1,3-thiazole-5-carboxamide
Show/Hide
|
C32H32N8O4S
|
1
|
| 1 |
IC50 = 83.9 nM
|
|
|
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CP0363575
|
2-(2-acetamidopyridin-4-yl)-4-(cyclopropylmethoxy)-N-[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]-1,3-thiazole-5-carboxamide
Show/Hide
|
C31H34N6O3S
|
1
|
| 1 |
IC50 = 92.8 nM
|
|
|
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CP0483866
|
4-[(1-benzylpiperidin-4-yl)methoxy]-2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-1,3-thiazole-5-carboxamide
Show/Hide
|
C26H29N5O3S
|
1
|
| 1 |
IC50 = 94 nM
|
|
|
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CP0560477
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[12-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxydodecoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C39H46N6O8S
|
1
|
| 1 |
IC50 = 98 nM
|
|
|
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CP0552174
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-(cyclopropylmethoxy)-N-[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]-1,3-thiazole-5-carboxamide
Show/Hide
|
C33H36N6O3S
|
1
|
| 1 |
IC50 = 103.6 nM
|
|
|
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CP0017214
|
1-(4-methoxybenzyl)-3-(5-nitrothiazol-2-yl)urea
Show/Hide
|
C12H12N4O4S
|
1
|
| 1 |
IC50 = 104 nM
|
|
|
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CP0560478
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[2-[2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyethoxy]ethoxy]ethoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C33H34N6O10S
|
1
|
| 1 |
IC50 = 104.9 nM
|
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CP0251287
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4-(cyclopropylmethoxy)-N-ethyl-2-[2-[[2-[2-(1,2,3,4-tetrahydroacridin-9-ylamino)ethylamino]acetyl]amino]pyridin-4-yl]-1,3-thiazole-5-carboxamide
Show/Hide
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C32H37N7O3S
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1
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| 1 |
IC50 = 114.4 nM
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CP0572922
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4-(cyclobutylmethoxy)-N-methyl-2-[2-[[2-[2-(1,2,3,4-tetrahydroacridin-9-ylamino)ethylamino]acetyl]amino]pyridin-4-yl]-1,3-thiazole-5-carboxamide
Show/Hide
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C32H37N7O3S
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1
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| 1 |
IC50 = 130.4 nM
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CP0219132
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N-methyl-4-(2-methylpropoxy)-2-[2-[[2-[2-(1,2,3,4-tetrahydroacridin-9-ylamino)ethylamino]acetyl]amino]pyridin-4-yl]-1,3-thiazole-5-carboxamide
Show/Hide
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C31H37N7O3S
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1
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| 1 |
IC50 = 132.4 nM
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CP0578720
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4-(2,2-dimethylpropoxy)-N-methyl-2-[2-[[2-[2-(1,2,3,4-tetrahydroacridin-9-ylamino)ethylamino]acetyl]amino]pyridin-4-yl]-1,3-thiazole-5-carboxamide
Show/Hide
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C32H39N7O3S
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1
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| 1 |
IC50 = 165.3 nM
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CP0352701
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2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[1-(pyridin-2-ylmethyl)piperidin-4-yl]ethoxy]-1,3-thiazole-5-carboxamide
Show/Hide
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C26H30N6O3S
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1
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| 1 |
IC50 = 193 nM
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CP0570071
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4-(cyclopropylmethoxy)-N-propyl-2-[2-[[2-[2-(1,2,3,4-tetrahydroacridin-9-ylamino)ethylamino]acetyl]amino]pyridin-4-yl]-1,3-thiazole-5-carboxamide
Show/Hide
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C33H39N7O3S
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1
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| 1 |
IC50 = 239.3 nM
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CP0552584
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2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-N-[6-[[2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetyl]amino]hexyl]-4-methoxy-1,3-thiazole-5-carboxamide
Show/Hide
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C35H37N7O9S
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1
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| 1 |
IC50 = 242.7 nM
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CP0251449
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2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[1-[(2-fluorophenyl)methyl]piperidin-4-yl]ethoxy]-1,3-thiazole-5-carboxamide
Show/Hide
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C27H30FN5O3S
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1
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| 1 |
IC50 = 261 nM
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CP0546154
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2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[5-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-4-yl]pent-4-ynoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
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C32H30N6O6S
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1
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| 1 |
IC50 = 294.7 nM
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CP0569285
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2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-N-[4-[[2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetyl]amino]butyl]-4-methoxy-1,3-thiazole-5-carboxamide
Show/Hide
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C33H33N7O9S
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1
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| 1 |
IC50 = 639.2 nM
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CP0564134
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2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-N-[3-[[2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetyl]amino]propyl]-4-methoxy-1,3-thiazole-5-carboxamide
Show/Hide
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C32H31N7O9S
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1
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| 1 |
IC50 = 874.3 nM
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CP0016948
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4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione
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C10H10N2O2S
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1
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| 1 |
IC50 = 1400 nM
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CP0366627
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4-ethyl-2-(4-hexadecanoylpiperazine-1-carbonyl)-1,4-benzothiazin-3-one
Show/Hide
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C31H49N3O3S
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1
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| 1 |
IC50 = 8700 nM
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CP0127677
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N-[1-(4-ethyl-3-oxo-1,4-benzothiazine-2-carbonyl)piperidin-4-yl]hexadecanamide
Show/Hide
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C32H51N3O3S
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1
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| 1 |
IC50 = 11700 nM
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CP0360928
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N'-dodecanoyl-4-ethyl-3-oxo-1,4-benzothiazine-2-carbohydrazide
Show/Hide
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C23H35N3O3S
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1
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| 1 |
IC50 = 11900 nM
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CP0959742
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4-Ethyl-3-oxo-N-(1-pentadecanoylpiperidin-4-yl)-3,4-dihydro-2H-benzo[b][1,4]thiazine-2-carboxamide
Show/Hide
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C31H49N3O3S
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1
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| 1 |
IC50 = 17900 nM
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CP0924447
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4-Ethyl-3-oxo-N-(1-palmitoylpiperidin-4-yl)-3,4-dihydro-2H-benzo[b][1,4]thiazine-2-carboxamide
Show/Hide
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C32H51N3O3S
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1
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| 1 |
IC50 = 18600 nM
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CP0408825
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4-ethyl-2-(4-tetradecanoylpiperazine-1-carbonyl)-1,4-benzothiazin-3-one
Show/Hide
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C29H45N3O3S
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1
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| 1 |
IC50 = 18900 nM
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CP0023996
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N-[1-(4-ethyl-3-oxo-1,4-benzothiazine-2-carbonyl)piperidin-4-yl]pentadecanamide
Show/Hide
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C31H49N3O3S
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1
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| 1 |
IC50 = 22400 nM
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CP0964889
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N-dodecyl-4-ethyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-2-carboxamide
Show/Hide
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C23H36N2O2S
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1
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| 1 |
IC50 = 22900 nM
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CP0329998
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2-(4-dodecanoylpiperazine-1-carbonyl)-4-ethyl-1,4-benzothiazin-3-one
Show/Hide
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C27H41N3O3S
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1
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| 1 |
IC50 = 23200 nM
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CP0950887
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4-Ethyl-2-(4-undecanoylpiperazine-1-carbonyl)-2H-benzo[b][1,4]thiazin-3(4H)-one
Show/Hide
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C26H39N3O3S
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1
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| 1 |
IC50 = 27100 nM
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CP0954636
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4-Ethyl-3-oxo-N-(1-tetradecanoylpiperidin-4-yl)-3,4-dihydro-2H-benzo[b][1,4]thiazine-2-carboxamide
Show/Hide
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C30H47N3O3S
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1
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| 1 |
IC50 = 27300 nM
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CP0930477
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N-(1-dodecanoylpiperidin-4-yl)-4-ethyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-2-carboxamide
Show/Hide
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C28H43N3O3S
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1
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| 1 |
IC50 = 29700 nM
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CP0930478
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N-(1-(4-Ethyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-2-carbonyl)piperidin-4-yl)-tetradecanamide
Show/Hide
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C30H47N3O3S
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1
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| 1 |
IC50 = 33400 nM
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CP0968829
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N-(1-(4-Ethyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-2-carbonyl)piperidin-4-yl)-dodecanamide
Show/Hide
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C28H43N3O3S
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1
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| 1 |
IC50 = 33400 nM
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CP0954635
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4-Ethyl-3-oxo-N-(1-undecanoylpiperidin-4-yl)-3,4-dihydro-2H-benzo[b][1,4]thiazine-2-carboxamide
Show/Hide
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C27H41N3O3S
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1
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| 1 |
IC50 = 44300 nM
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CP0959743
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N-(1-(4-Ethyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-2-carbonyl)piperidin-4-yl)-undecanamide
Show/Hide
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C27H41N3O3S
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1
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| 1 |
IC50 = 45900 nM
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CP0954109
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N-(1-(4-Ethyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-2-carbonyl)piperidin-4-yl)-heptadecanamide
Show/Hide
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C33H53N3O3S
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1
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| 1 |
IC50 = 46700 nM
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CP0931147
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2-(4-Decanoylpiperazine-1-carbonyl)-4-ethyl-2H-benzo[b][1,4]thiazin-3(4H)-one
Show/Hide
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C25H37N3O3S
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1
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| 1 |
IC50 = 51700 nM
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CP0954107
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N-(1-(4-Ethyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-2-carbonyl)piperidin-4-yl)-decanamide
Show/Hide
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C26H39N3O3S
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1
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| 1 |
IC50 = 68300 nM
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CP0853919
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N-(1-decanoylpiperidin-4-yl)-4-ethyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-2-carboxamide
Show/Hide
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C26H39N3O3S
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1
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| 1 |
IC50 = 74900 nM
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CP0902470
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N-(1-(4-Ethyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-2-carbonyl)piperidin-4-yl)-nonanamide
Show/Hide
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C25H37N3O3S
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1
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| 1 |
IC50 > 100000 nM
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CP0904855
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4-Ethyl-N-(1-nonanoylpiperidin-4-yl)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-2-carboxamide
Show/Hide
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C25H37N3O3S
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1
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| 1 |
IC50 > 100000 nM
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CP0904856
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N-(1-(4-Ethyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-2-carbonyl)piperidin-4-yl)-6-phenylhexanamide
Show/Hide
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C28H35N3O3S
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1
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| 1 |
IC50 > 100000 nM
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CP0959745
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4-Ethyl-2-(4-nonanoylpiperazine-1-carbonyl)-2H-benzo[b][1,4]thiazin-3(4H)-one
Show/Hide
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C24H35N3O3S
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1
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| 1 |
IC50 > 100000 nM
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CP0012721
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[3-[4-[(4-cyclopropylphenyl)methoxy]-3-methoxyphenyl]azetidin-1-yl]-[4-[[(2S)-2,3-dihydroxypropoxy]methyl]pyridin-2-yl]methanone
Show/Hide
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C30H34N2O6
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1
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| 1 |
IC50 > 1000 nM
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CP0001598
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1,2,3,4-tetrahydro-9-acridinamine
Show/Hide
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C13H14N2
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1
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| 1 |
IC50 > 1000 nM
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CP0013001
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(+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-indan-1-one
Show/Hide
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C24H29NO3
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1
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| 1 |
IC50 > 1000 nM
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CP0426369
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2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[4-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]but-3-ynoxy]-1,3-thiazole-5-carboxamide
Show/Hide
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C30H24N6O7S
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1
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| 1 |
IC50 > 1000 nM
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CP0486329
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2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[4-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-4-yl]but-3-ynoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
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C31H28N6O6S
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1
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| 1 |
IC50 > 1000 nM
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CP0902817
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(2S,3R)-((1R,3S)-3-(3-(2-(6-methoxypyridin-3-yl)acetamido)-1H-pyrazol-5-yl)cyclopentyl)3-cyano-2-methylazetidine-1-carboxylate
Show/Hide
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C22H26N6O4
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1
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| 1 |
Ki = 0.78 nM
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CP0953378
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(1S,3R)-3-(3-(2-(6-methoxypyridin-3-yl)acetamido)-1H-pyrazol-5-yl)cyclopentyl 2,2-dimethylazetidine-1-carboxylate
Show/Hide
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C22H29N5O4
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1
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| 1 |
Ki = 0.95 nM
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CP0871811
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(1R,3S)-3-(3-(2-(6-methoxypyridin-3-yl)acetamido)-1H-pyrazol-5-yl)cyclopentyl 2,2-dimethylazetidine-1-carboxylate
Show/Hide
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C22H29N5O4
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1
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| 1 |
Ki = 1.26 nM
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CP0943873
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(1R,3S)-3-(3-(2-(6-methoxypyridin-3-yl)acetamido)-1H-pyrazol-5-yl)cyclopentyl 2-(hydroxymethyl)butylcarbamate
Show/Hide
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C22H31N5O5
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1
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| 1 |
Ki = 1.41 nM
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CP0902818
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(2S,3R)-((1R,3S)-3-(3-(2-(2-methylthiazol-5-yl)acetamido)-1H-pyrazol-5-yl)cyclopentyl)3-cyano-2-methylazetidine-1-carboxylate
Show/Hide
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C20H24N6O3S
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1
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| 1 |
Ki = 1.72 nM
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CP0902819
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(1S,3R)-3-(3-(2-(6-methoxypyridin-3-yl)acetamido)-1H-pyrazol-5-yl)cyclopentyl (1r,4S)-4-hydroxycyclohexylcarbamate
Show/Hide
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C23H31N5O5
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1
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| 1 |
Ki = 1.85 nM
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CP0409691
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AZ-11548415
Show/Hide
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C19H18N4O2
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1
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| 1 |
Ki = 31 nM
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