| Compound ID |
Compound Name |
Compound Formula |
|
CP0117839
|
N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C26H29FN4O4S
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0117838
|
N-[(2R)-1-(3-hydroxypropylamino)-3-methyl-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C27H32N4O5S
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0117832
|
N-[(2S)-1-(3-hydroxypropylamino)-3-methyl-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C27H32N4O5S
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0235666
|
N-[(2S)-1-[[(2S)-2,3-dihydroxypropyl]amino]-3-methyl-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C27H32N4O6S
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0159080
|
N-[(2S)-1-[[(2R)-2,3-dihydroxypropyl]amino]-3-methyl-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C27H32N4O6S
|
1
|
| 1 |
IC50 = 83 nM
|
|
|
|
CP0081669
|
N-[(2R)-1-[[(2S)-2,3-dihydroxypropyl]amino]-3-methyl-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C27H32N4O6S
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0117836
|
5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(1S)-2-(methylamino)-1-(oxan-4-yl)-2-oxoethyl]furan-2-carboxamide
Show/Hide
|
C27H29FN4O5S
|
1
|
| 1 |
IC50 = 113 nM
|
|
|
|
CP0412434
|
N-[(2R)-1-[[(2R)-2,3-dihydroxypropyl]amino]-3-methyl-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C27H32N4O6S
|
1
|
| 1 |
IC50 = 117 nM
|
|
|
|
CP0235665
|
5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2S)-3-hydroxy-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C25H27FN4O5S
|
1
|
| 1 |
IC50 = 128 nM
|
|
|
|
CP0068679
|
N-[(2S)-1-(2-aminoethylamino)-3-methyl-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C26H31N5O4S
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0353851
|
5-[3-fluoro-4-[(6-fluoro-4-oxo-3H-quinazolin-2-yl)sulfanylmethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C26H24F2N4O4S
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0370129
|
5-[3-fluoro-4-[(4-oxo-3H-quinazolin-2-yl)sulfanylmethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C26H25FN4O4S
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0236957
|
N-[(1S)-1-cyclopropyl-2-(methylamino)-2-oxoethyl]-5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C25H25FN4O4S
|
1
|
| 1 |
IC50 = 832 nM
|
|
|
|
CP0068681
|
2-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C24H26FN5O3S2
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0159064
|
N-[(2S)-1-(cyclopropylamino)-3-methyl-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C27H30N4O4S
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0069584
|
N-[(2R)-1-(azetidin-3-ylamino)-3-methyl-1-oxobutan-2-yl]-5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C27H30FN5O4S
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0099232
|
5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C25H27FN4O4S
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0117834
|
5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2R)-3-methyl-1-(oxetan-3-ylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C27H29FN4O5S
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0117835
|
5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2R)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C25H27FN4O4S
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0117840
|
5-[3-fluoro-4-[2-(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)ethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C26H29FN4O4
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0159065
|
N-[(2S)-1-[[(1R,2R)-2-hydroxycyclohexyl]amino]-3-methyl-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C30H36N4O5S
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0159066
|
N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]-5-[6-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]pyridin-3-yl]furan-2-carboxamide
Show/Hide
|
C24H27N5O4S
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0159067
|
5-[3-fluoro-4-[[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)amino]methyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C25H28FN5O4
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0159081
|
N-[(1R)-1-cyclohexyl-2-(methylamino)-2-oxoethyl]-5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C28H31FN4O4S
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0159082
|
5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[1-(methylcarbamoyl)cyclohexyl]furan-2-carboxamide
Show/Hide
|
C27H29FN4O4S
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0159083
|
5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)oxymethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C25H27FN4O5
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0228998
|
N-[(1S)-1-cyclohexyl-2-(methylamino)-2-oxoethyl]-5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C28H31FN4O4S
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0253210
|
5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2S)-1-[[(1R,2R)-2-hydroxycyclohexyl]amino]-3-methyl-1-oxobutan-2-yl]furan-2-carboxamide
Show/Hide
|
C30H35FN4O5S
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0387333
|
N-[(2R)-1-(2-aminoethylamino)-3-methyl-1-oxobutan-2-yl]-5-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
Show/Hide
|
C26H31N5O4S
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
