Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(1S)-2-(methylamino)-1-(oxan-4-yl)-2-oxoethyl]furan-2-carboxamide
    Show/Hide
 PubChem ID
CID: 145949693
Canonical SMILES
CNC(=O)[C@@H](NC(=O)c1ccc(o1)-c1ccc(CSc2nc3CCCc3c(=O)[nH]2)c(F)c1)C1CCOCC1
    Show/Hide
Compound Formula C27H29FN4O5S
Compound Structure
Protein Name
 Protein Info 
Neutrophil collagenase
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MAM clan
>
Metallo protease M10A subfamily
Uniprot ID
P22894
Gene Name
MMP8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000265 NS0
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 113 nM
   TI
   LI
   LO
   TS